PL318501A1 - Pharmaceutic compositions containing a tnc bonding chimeric protein - Google Patents

Pharmaceutic compositions containing a tnc bonding chimeric protein

Info

Publication number
PL318501A1
PL318501A1 PL95318501A PL31850195A PL318501A1 PL 318501 A1 PL318501 A1 PL 318501A1 PL 95318501 A PL95318501 A PL 95318501A PL 31850195 A PL31850195 A PL 31850195A PL 318501 A1 PL318501 A1 PL 318501A1
Authority
PL
Poland
Prior art keywords
tnc
bonding
compositions containing
chimeric protein
pharmaceutic compositions
Prior art date
Application number
PL95318501A
Other languages
English (en)
Inventor
Robert Fredrick Geoffrey Booth
Werner Lesslauer
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of PL318501A1 publication Critical patent/PL318501A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • C07K14/7151—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for tumor necrosis factor [TNF], for lymphotoxin [LT]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Neurology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
PL95318501A 1994-07-22 1995-07-15 Pharmaceutic compositions containing a tnc bonding chimeric protein PL318501A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP94111455 1994-07-22
PCT/EP1995/002788 WO1996003141A1 (en) 1994-07-22 1995-07-15 Pharmaceutical compositions comprising a chimaeric tnf binding protein

Publications (1)

Publication Number Publication Date
PL318501A1 true PL318501A1 (en) 1997-06-23

Family

ID=8216138

Family Applications (1)

Application Number Title Priority Date Filing Date
PL95318501A PL318501A1 (en) 1994-07-22 1995-07-15 Pharmaceutic compositions containing a tnc bonding chimeric protein

Country Status (11)

Country Link
EP (1) EP0772449A1 (no)
JP (1) JPH09508140A (no)
AU (1) AU3111995A (no)
BR (1) BR9508419A (no)
CA (1) CA2195665A1 (no)
CZ (1) CZ283219B6 (no)
FI (1) FI970247A (no)
HU (1) HUT76666A (no)
NO (1) NO970264L (no)
PL (1) PL318501A1 (no)
WO (1) WO1996003141A1 (no)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6350730B1 (en) 1994-08-17 2002-02-26 The Rockefeller University OB polypeptides and modified forms as modulators of body weight
US6471956B1 (en) 1994-08-17 2002-10-29 The Rockefeller University Ob polypeptides, modified forms and compositions thereto
US6001968A (en) 1994-08-17 1999-12-14 The Rockefeller University OB polypeptides, modified forms and compositions
US6429290B1 (en) 1994-08-17 2002-08-06 The Rockefeller University OB polypeptides, modified forms and derivatives
US6936439B2 (en) 1995-11-22 2005-08-30 Amgen Inc. OB fusion protein compositions and methods
US20030040467A1 (en) 1998-06-15 2003-02-27 Mary Ann Pelleymounter Ig/ob fusions and uses thereof.
CN1233189A (zh) * 1996-05-08 1999-10-27 弗·哈夫曼-拉罗切有限公司 用TNFR-Ig治疗哮喘
TW555765B (en) * 1996-07-09 2003-10-01 Amgen Inc Low molecular weight soluble tumor necrosis factor type-I and type-II proteins
US7070771B1 (en) 1996-12-09 2006-07-04 Regents Of The University Of California Methods of expressing chimeric mouse and human CD40 ligand in human CD40+ cells
EP0948543A1 (en) * 1996-12-12 1999-10-13 Genentech, Inc. Hvem polypeptides and uses thereof
ATE250784T1 (de) 1998-11-27 2003-10-15 Synaptics Uk Ltd Positionssensor
HUP0303246A2 (hu) 2001-02-23 2003-12-29 Immunex Corporation Aktív fehérjék fokozott kinyerése
WO2003011323A1 (en) * 2001-07-30 2003-02-13 Genset S.A. Agonists and antagonists of contabix for use in the treatment of metabolic disorders
US7786282B2 (en) 2001-12-06 2010-08-31 The Regents Of The University Of California Nucleic acid molecules encoding TNF-α ligand polypeptides having a CD154 domain
PT1471974E (pt) 2002-02-06 2007-10-12 Ares Trading Sa Factor de necrose tumural combinado com interferão em doenças desmielinizantes
JP5553963B2 (ja) 2004-10-22 2014-07-23 アムジエン・インコーポレーテツド 組換え抗体をリフォールディングする方法
CA2958578A1 (en) 2014-08-21 2016-02-25 The General Hospital Corporation Tumor necrosis factor superfamily and tnf-like ligand muteins and methods of preparing and using the same

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL98078A0 (en) * 1991-05-07 1992-06-21 Yeda Res & Dev Pharmaceutical compositions comprising an anticytokyne
DK0417563T3 (da) * 1989-09-12 2000-11-06 Hoffmann La Roche TNF-bindende proteiner
GB9015908D0 (en) * 1990-07-19 1990-09-05 Celltech Ltd Multivalent immunoglobulin
KR100232688B1 (ko) * 1992-09-15 1999-12-01 스코트 쥐. 홀퀴스트 종양 괴사 인자 길항제를 함유하는 tnf-의존성 염증 치료용 제약 조성물
CA2147180A1 (en) * 1992-10-15 1994-04-28 Gokhan S. Hotamisligil Treatment of insulin resistance in obesity linked type ii diabetes using antagonists to tnf-.alpha. function

Also Published As

Publication number Publication date
AU3111995A (en) 1996-02-22
HUT76666A (en) 1997-10-28
CZ283219B6 (cs) 1998-02-18
WO1996003141A1 (en) 1996-02-08
NO970264L (no) 1997-03-24
CA2195665A1 (en) 1996-02-08
BR9508419A (pt) 1997-11-18
FI970247A0 (fi) 1997-01-21
CZ19397A3 (en) 1997-06-11
NO970264D0 (no) 1997-01-21
EP0772449A1 (en) 1997-05-14
FI970247A (fi) 1997-01-21
JPH09508140A (ja) 1997-08-19

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