PL297716A1 - Benzimidazolyl derivatives, method of obtaining them and therapeutic agents containing such compounds - Google Patents
Benzimidazolyl derivatives, method of obtaining them and therapeutic agents containing such compoundsInfo
- Publication number
- PL297716A1 PL297716A1 PL29771693A PL29771693A PL297716A1 PL 297716 A1 PL297716 A1 PL 297716A1 PL 29771693 A PL29771693 A PL 29771693A PL 29771693 A PL29771693 A PL 29771693A PL 297716 A1 PL297716 A1 PL 297716A1
- Authority
- PL
- Poland
- Prior art keywords
- compounds
- obtaining
- therapeutic agents
- agents containing
- benzimidazolyl derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains three hetero rings
- C07D513/14—Ortho-condensed systems
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE4204270A DE4204270A1 (de) | 1992-02-13 | 1992-02-13 | Benzimidazolylderivate, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL297716A1 true PL297716A1 (en) | 1994-01-24 |
Family
ID=6451613
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL29771693A PL297716A1 (en) | 1992-02-13 | 1993-02-12 | Benzimidazolyl derivatives, method of obtaining them and therapeutic agents containing such compounds |
Country Status (18)
Families Citing this family (37)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4129603A1 (de) * | 1991-09-06 | 1993-03-11 | Thomae Gmbh Dr K | Kondensierte 5-gliedrige heterocyclen, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
| DE4430755A1 (de) * | 1994-08-30 | 1996-03-07 | Boehringer Mannheim Gmbh | Neue Phosphanoxide, Verfahren zu ihrer Herstellung sowie diese Verbindungen enthaltende Arzneimittel |
| IL115420A0 (en) | 1994-09-26 | 1995-12-31 | Zeneca Ltd | Aminoheterocyclic derivatives |
| GB9505538D0 (en) * | 1995-03-18 | 1995-05-03 | Ciba Geigy Ag | New compounds |
| EP0880501A1 (en) | 1996-02-02 | 1998-12-02 | Zeneca Limited | Heterocyclic compounds useful as pharmaceutical agents |
| GB9602166D0 (en) * | 1996-02-02 | 1996-04-03 | Zeneca Ltd | Aminoheterocyclic derivatives |
| GB9602294D0 (en) * | 1996-02-05 | 1996-04-03 | Zeneca Ltd | Heterocyclic compounds |
| GB9611461D0 (en) * | 1996-06-01 | 1996-08-07 | Ciba Geigy Ag | New compounds |
| SK18499A3 (en) * | 1996-08-14 | 1999-07-12 | Zeneca Ltd | Substituted pyrimidine derivatives and their pharmaceutical use |
| KR20000068415A (ko) * | 1996-09-04 | 2000-11-25 | 로즈 암스트롱, 크리스틴 에이. 트러트웨인 | 매트릭스 메탈로프로테이나제 억제용 화합물 및 방법 |
| US6011155A (en) * | 1996-11-07 | 2000-01-04 | Novartis Ag | N-(substituted glycyl)-2-cyanopyrrolidines, pharmaceutical compositions containing them and their use in inhibiting dipeptidyl peptidase-IV |
| UA56197C2 (uk) | 1996-11-08 | 2003-05-15 | Зенека Лімітед | Гетероциклічні похідні |
| US6391880B1 (en) | 1997-02-13 | 2002-05-21 | Zeneca Limited | Heterocyclic compounds useful as oxido-squalene cyclase inhibitors |
| WO1998035956A1 (en) | 1997-02-13 | 1998-08-20 | Zeneca Limited | Heterocyclic compounds useful as oxido-squalene cyclase inhibitors |
| KR100361827B1 (ko) * | 1997-04-07 | 2003-01-24 | 주식회사 엘지생명과학 | 트롬빈 억제제로서 유용한 헤테로사이클릭알라닌 유도체 |
| IL123986A (en) | 1997-04-24 | 2011-10-31 | Organon Nv | Medicinal compounds |
| GB9715895D0 (en) | 1997-07-29 | 1997-10-01 | Zeneca Ltd | Heterocyclic compounds |
| US6350885B1 (en) | 1998-07-30 | 2002-02-26 | Warner-Lambert Company | Tricyclic heteroaromatics and their derivatives as inhibitors of matrix metalloproteinases |
| AP2001002037A0 (en) | 1998-07-30 | 2001-03-31 | Warner Lambert Co | Tricyclic sulfonamides and their derivatives as inhibitors of matrix metalloproteinases. |
| CO5150173A1 (es) * | 1998-12-10 | 2002-04-29 | Novartis Ag | Compuestos n-(glicilo sustituido)-2-cianopirrolidinas inhibidores de peptidasa de dipeptidilo-iv (dpp-iv) los cuales son efectivos en el tratamiento de condiciones mediadas por la inhibicion de dpp-iv |
| GB9902989D0 (en) | 1999-02-11 | 1999-03-31 | Zeneca Ltd | Heterocyclic derivatives |
| US6713473B1 (en) | 1999-04-20 | 2004-03-30 | Meiji Seika Kaisha, Ltd. | Tricyclic compounds |
| US6172081B1 (en) | 1999-06-24 | 2001-01-09 | Novartis Ag | Tetrahydroisoquinoline 3-carboxamide derivatives |
| US6110949A (en) * | 1999-06-24 | 2000-08-29 | Novartis Ag | N-(substituted glycyl)-4-cyanothiazolidines, pharmaceutical compositions containing them and their use in inhibiting dipeptidyl peptidase-IV |
| US6617340B1 (en) | 1999-07-29 | 2003-09-09 | Novartis Ag | N-(substituted glycyl)-pyrrolidines, pharmaceutical compositions containing them and their use in inhibiting dipeptidyl peptidase-IV |
| US7229986B2 (en) | 2000-05-16 | 2007-06-12 | Takeda Pharmaceutical Company Ltd. | Melanin-concentrating hormone antagonist |
| CA2545644C (en) * | 2003-11-12 | 2011-11-01 | Lg Life Sciences Ltd. | Melanocortin receptor agonists |
| CN101277949A (zh) * | 2005-04-22 | 2008-10-01 | 阿兰托斯制药控股公司 | 二肽基肽酶-ⅳ抑制剂 |
| KR101772834B1 (ko) | 2009-12-04 | 2017-08-29 | 선오비온 파마슈티컬스 인코포레이티드 | 다환형 화합물 및 이의 사용 방법 |
| CN110087687A (zh) | 2016-07-29 | 2019-08-02 | 赛诺维信制药公司 | 化合物、组合物及其用途 |
| HRP20241631T1 (hr) | 2016-07-29 | 2025-02-28 | Sumitomo Pharma America, Inc. | Spojevi i pripravci i njihove uporabe |
| WO2018118838A1 (en) * | 2016-12-20 | 2018-06-28 | Biomarin Pharmaceutical Inc. | Ceramide galactosyltransferase inhibitors for the treatment of disease |
| IL303177A (en) | 2017-02-16 | 2023-07-01 | Sunovion Pharmaceuticals Inc | Treatment of schizophrenia |
| BR112020001433A2 (pt) | 2017-08-02 | 2020-07-28 | Sunovion Pharmaceuticals Inc. | compostos de isocromano e usos dos mesmos |
| KR102746817B1 (ko) | 2018-02-16 | 2024-12-24 | 스미토모 파마 아메리카, 인크. | 염, 결정 형태 및 이들의 제조 방법 |
| WO2020186165A1 (en) | 2019-03-14 | 2020-09-17 | Sunovion Pharmaceuticals Inc. | Salts of a isochromanyl compound and crystalline forms, processes for preparing, therapeutic uses, and pharmaceutical compositions thereof |
| JP2023523569A (ja) | 2020-04-14 | 2023-06-06 | サノビオン ファーマシューティカルズ インク | 神経学的および精神障害の治療方法 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DD142804A3 (de) * | 1977-11-07 | 1980-07-16 | Wagner Guenter | Verfahren zur herstellung von na-alkyl-bzw.na-aryl-sulfonylierten omega-amidinophenyl-alpha-aminoalkylcarbonsaeureamiden |
| SE8203887D0 (sv) * | 1982-06-23 | 1982-06-23 | Kabivitrum Ab | Nya trombininhiberande foreningar |
| EP0511347A1 (de) * | 1990-11-15 | 1992-11-04 | Pentapharm A.G. | Meta-substituierte phenylalanin-derivate |
-
1992
- 1992-01-12 PH PH45722A patent/PH31294A/en unknown
- 1992-02-13 DE DE4204270A patent/DE4204270A1/de not_active Withdrawn
-
1993
- 1993-01-20 TW TW082100359A patent/TW222271B/zh active
- 1993-02-08 US US08/014,598 patent/US5391556A/en not_active Expired - Fee Related
- 1993-02-10 EP EP93102052A patent/EP0555824A1/de not_active Ceased
- 1993-02-11 NZ NZ245886A patent/NZ245886A/en unknown
- 1993-02-11 MX MX9300735A patent/MX9300735A/es not_active IP Right Cessation
- 1993-02-11 AU AU32968/93A patent/AU663556B2/en not_active Ceased
- 1993-02-11 KR KR1019930001831A patent/KR930017900A/ko not_active Ceased
- 1993-02-12 PL PL29771693A patent/PL297716A1/xx unknown
- 1993-02-12 ZA ZA93975A patent/ZA93975B/xx unknown
- 1993-02-12 JP JP5024205A patent/JPH0616648A/ja active Pending
- 1993-02-12 HU HU9300385A patent/HUT63624A/hu unknown
- 1993-02-12 CA CA002089466A patent/CA2089466A1/en not_active Abandoned
- 1993-02-12 IL IL104703A patent/IL104703A/xx not_active IP Right Cessation
- 1993-02-12 CZ CZ93185A patent/CZ18593A3/cs unknown
- 1993-02-12 NO NO93930517A patent/NO930517L/no unknown
- 1993-02-12 FI FI930620A patent/FI930620A7/fi unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US5391556A (en) | 1995-02-21 |
| JPH0616648A (ja) | 1994-01-25 |
| NO930517L (no) | 1993-08-16 |
| IL104703A (en) | 1997-07-13 |
| HUT63624A (en) | 1993-09-28 |
| CZ18593A3 (en) | 1993-12-15 |
| FI930620A7 (fi) | 1993-08-14 |
| AU663556B2 (en) | 1995-10-12 |
| CA2089466A1 (en) | 1993-08-14 |
| PH31294A (en) | 1998-07-06 |
| HU9300385D0 (en) | 1993-04-28 |
| ZA93975B (en) | 1994-08-12 |
| KR930017900A (ko) | 1993-09-20 |
| DE4204270A1 (de) | 1993-11-04 |
| MX9300735A (es) | 1993-08-01 |
| NO930517D0 (no) | 1993-02-12 |
| NZ245886A (en) | 1995-12-21 |
| TW222271B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1994-04-11 |
| FI930620A0 (fi) | 1993-02-12 |
| AU3296893A (en) | 1993-08-19 |
| EP0555824A1 (de) | 1993-08-18 |
| IL104703A0 (en) | 1993-06-10 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| PL297716A1 (en) | Benzimidazolyl derivatives, method of obtaining them and therapeutic agents containing such compounds | |
| PL300335A1 (en) | Pharmaceutical agent, novel derivatives of 4-thiazinylinone and method of obtaining such novel derivatives | |
| PL301396A1 (en) | Derivatives of carboxylic acids, therapeutic agent containing such compounds and method of obtaining them | |
| PL313433A1 (en) | Derivatives of benzazepin-, benzoxazepin- and benzothiazepin-n-acetic acids, method of obtaining them and therapeutic agents containing such derivatives | |
| PL297870A1 (en) | Substituted sulfonylbenzylopyridones as well as method of obtaining and drugs containing them | |
| PL300673A1 (en) | Derivatives of carboxylic acids, therapeutic agents containing them and method of obtaining sames | |
| PL299176A1 (en) | Novel heterocyclic compounds, pharmaceutical agent, method of obtaining such novel heterocyclic compounds and initial compounds for obtaining them | |
| PL311999A1 (en) | Piperazine derivatives, therapeutic agents containing them and method of obtaining such derivatives | |
| HUT64774A (en) | Method for producing peptones inhibiting activity of hiv-protease and one for prdeparing such medical preparatives | |
| PL321201A1 (en) | Derivatives of 4-hydroxypiepridine, method of obtaining them and therapeutic agents containing such derivatives | |
| PL307669A1 (en) | Benzimidazoles, therapeutic agents containing them and method of obtaining such compounds | |
| PL299260A1 (en) | Biphenyl derivatives, therapeutic agents containing them and method of obtaining the sames | |
| PL324436A1 (en) | Novel derivatives of oxazolydinone, method of obtaining them and therapeutic agents containing such compounds | |
| ZA9410056B (en) | Indoline derivatives method of preparation and use | |
| HUT53779A (en) | Insecticide preparations containing phenyl-substituted heterocyclic compounds as agents and method for producing the agents | |
| PL308361A1 (en) | Novel taxane derivatives, method of obtaining them and pharmaceutical agents containing such derivatives | |
| PL299754A1 (en) | Benzimidazoles, therapeutic agent containing them and method of obtaining the sames | |
| PL298718A1 (en) | Cyclic imine derivatives, therapeutic agents containing such compounds and method of obtaining them | |
| PL301059A1 (en) | Novel quinoline derivatives, method of obtaining quinoline derivatives and pharmaceutical agent containing them | |
| PL298449A1 (en) | Novel benzimidazoles, method of obtaining sames and therapeutic agents containing them | |
| PL301187A1 (en) | Derivatives of 2-alkoxt 2-imidazolyn-5-ones, method of obtaining them and fungicides containing such compounds | |
| GB2267089B (en) | Cycloheptimidazole derivatives,method of manufacturing the same and therapeutic agents containing these compounds | |
| PL300585A1 (en) | Benzimidazoles, therapeutic agents containing them and method of obtaining sames | |
| PL311467A1 (en) | Substituted benzoyloguanidines, method of obtaining them and therapeutic agent containing such compounds | |
| PL301355A1 (en) | Sybstituted hydroxy cimmamides, method of obtaining them and agents containing such compounds and their application |