PL2959005T3 - Zastosowanie medyczne dotyczące wydłużania telomerów - Google Patents
Zastosowanie medyczne dotyczące wydłużania telomerówInfo
- Publication number
- PL2959005T3 PL2959005T3 PL14754545T PL14754545T PL2959005T3 PL 2959005 T3 PL2959005 T3 PL 2959005T3 PL 14754545 T PL14754545 T PL 14754545T PL 14754545 T PL14754545 T PL 14754545T PL 2959005 T3 PL2959005 T3 PL 2959005T3
- Authority
- PL
- Poland
- Prior art keywords
- medical use
- use relating
- telomere extension
- telomere
- extension
- Prior art date
Links
- 210000003411 telomere Anatomy 0.000 title 1
- 102000055501 telomere Human genes 0.000 title 1
- 108091035539 telomere Proteins 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
- A61K31/7115—Nucleic acids or oligonucleotides having modified bases, i.e. other than adenine, guanine, cytosine, uracil or thymine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/45—Transferases (2)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/12—Ophthalmic agents for cataracts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/52—Genes encoding for enzymes or proenzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
- C12N9/1241—Nucleotidyltransferases (2.7.7)
- C12N9/1276—RNA-directed DNA polymerase (2.7.7.49), i.e. reverse transcriptase or telomerase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y207/00—Transferases transferring phosphorus-containing groups (2.7)
- C12Y207/07—Nucleotidyltransferases (2.7.7)
- C12Y207/07049—RNA-directed DNA polymerase (2.7.7.49), i.e. telomerase or reverse-transcriptase
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- General Engineering & Computer Science (AREA)
- Diabetes (AREA)
- Physical Education & Sports Medicine (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Immunology (AREA)
- Hematology (AREA)
- Rheumatology (AREA)
- Ophthalmology & Optometry (AREA)
- Epidemiology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Obesity (AREA)
- Microbiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Urology & Nephrology (AREA)
- Psychiatry (AREA)
- Virology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361768047P | 2013-02-22 | 2013-02-22 | |
| EP14754545.3A EP2959005B1 (en) | 2013-02-22 | 2014-02-22 | Medical use relating to telomere extension |
| PCT/US2014/017867 WO2014130909A1 (en) | 2013-02-22 | 2014-02-22 | Compounds, compositions, methods, and kits relating to telomere extension |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL2959005T3 true PL2959005T3 (pl) | 2022-01-31 |
Family
ID=51388399
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL14754545T PL2959005T3 (pl) | 2013-02-22 | 2014-02-22 | Zastosowanie medyczne dotyczące wydłużania telomerów |
Country Status (21)
| Country | Link |
|---|---|
| US (6) | US10525075B2 (pl) |
| EP (2) | EP3988112B1 (pl) |
| JP (3) | JP2016514953A (pl) |
| CN (3) | CN105164269A (pl) |
| AU (1) | AU2014218667A1 (pl) |
| CA (1) | CA2902237C (pl) |
| CY (1) | CY1125092T1 (pl) |
| DK (1) | DK2959005T3 (pl) |
| ES (2) | ES2901402T3 (pl) |
| FI (1) | FI2959005T3 (pl) |
| HK (1) | HK1218934A1 (pl) |
| HR (1) | HRP20211842T1 (pl) |
| HU (1) | HUE056638T2 (pl) |
| IL (2) | IL240680B2 (pl) |
| LT (1) | LT2959005T (pl) |
| PL (1) | PL2959005T3 (pl) |
| PT (1) | PT2959005T (pl) |
| RS (1) | RS62824B1 (pl) |
| RU (2) | RU2022101438A (pl) |
| SI (1) | SI2959005T1 (pl) |
| WO (1) | WO2014130909A1 (pl) |
Families Citing this family (49)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111893140A (zh) | 2011-12-05 | 2020-11-06 | 菲克特生物科学股份有限公司 | 用于转染细胞的方法和产品 |
| US8497124B2 (en) | 2011-12-05 | 2013-07-30 | Factor Bioscience Inc. | Methods and products for reprogramming cells to a less differentiated state |
| CN115927242A (zh) | 2012-05-11 | 2023-04-07 | 珍白斯凯尔有限公司 | 具有抗炎活性的肽及其在制备抗炎组合物中的应用 |
| ES2981865T3 (es) | 2012-07-11 | 2024-10-10 | Gemvax & Kael Co Ltd | Conjugado que comprende un péptido de penetración celular y composiciones que comprenden el mismo |
| KR102315098B1 (ko) | 2012-11-01 | 2021-10-21 | 팩터 바이오사이언스 인크. | 세포에서 단백질을 발현시키는 방법들과 생성물들 |
| HUE056638T2 (hu) | 2013-02-22 | 2022-02-28 | Univ Leland Stanford Junior | Telomer kiterjesztéssel kapcsolatos gyógyászati alkalmazás |
| IL296889A (en) | 2013-10-30 | 2022-12-01 | Univ Missouri | A method for breeding and genealogical description of quantitative skeletal muscle |
| JP6367950B2 (ja) | 2013-12-17 | 2018-08-01 | ジェムバックス アンド カエル カンパニー,リミティド | 前立腺癌治療用組成物 |
| EP3690056B1 (en) | 2014-01-31 | 2022-12-28 | Factor Bioscience Inc. | Methods and products for nucleic acid production and delivery |
| KR102413243B1 (ko) | 2014-12-23 | 2022-06-27 | 주식회사 젬백스앤카엘 | 안질환 치료 펩티드 및 이를 포함하는 안질환 치료용 조성물 |
| IL253149B2 (en) | 2014-12-29 | 2023-11-01 | Novartis Ag | Methods of making chimeric antigen receptor-expressing cells |
| CA2976376A1 (en) | 2015-02-13 | 2016-08-18 | Factor Bioscience Inc. | Nucleic acid products and methods of administration thereof |
| CN107405380B (zh) * | 2015-02-27 | 2021-04-20 | 珍白斯凯尔有限公司 | 用于预防听觉损伤的肽及其包含该肽的组合物 |
| WO2016168595A1 (en) | 2015-04-17 | 2016-10-20 | Barrett David Maxwell | Methods for improving the efficacy and expansion of chimeric antigen receptor-expressing cells |
| ES2861001T3 (es) * | 2015-06-30 | 2021-10-05 | Ethris Gmbh | Polirribonucleótidos que codifican la familia del casete de unión a ATP y formulaciones de los mismos |
| EP3318265B1 (en) | 2015-07-02 | 2021-08-18 | Gemvax & Kael Co., Ltd. | Peptide having anti-viral effect and composition containing same |
| AR105433A1 (es) | 2015-07-21 | 2017-10-04 | Novartis Ag | Métodos para mejorar la eficacia y expansión de las células inmunes |
| CN108431021B (zh) * | 2015-11-03 | 2021-09-07 | 珍白斯凯尔有限公司 | 具有神经元损失预防和再生效果的肽以及包含该肽的组合物 |
| US20180360924A1 (en) * | 2015-11-25 | 2018-12-20 | The Methodist Hospital System | Telomere extension and anti-inflammatory agents for cell regeneration |
| CA3009852A1 (en) | 2015-12-28 | 2017-07-06 | Novartis Ag | Methods of making chimeric antigen receptor-expressing cells |
| ES2949697T3 (es) | 2016-04-07 | 2023-10-02 | Gemvax & Kael Co Ltd | Péptido que tiene efectos de aumento de la actividad telomerasa y de extensión de los telómeros, y composición que contienen el mismo |
| CN109689894A (zh) * | 2016-06-19 | 2019-04-26 | 耶路撒冷希伯来大学伊萨姆研发有限公司 | 在人单倍体细胞中筛选化学疗法抗性 |
| AU2017312113B2 (en) | 2016-08-17 | 2023-05-25 | Factor Bioscience Inc. | Nucleic acid products and methods of administration thereof |
| ES2985769T3 (es) | 2017-05-06 | 2024-11-07 | Upside Foods Inc | Composiciones y métodos para aumentar la densidad de cultivo de una biomasa celular dentro de una infraestructura de cultivo |
| WO2019014652A1 (en) | 2017-07-13 | 2019-01-17 | Memphis Meats, Inc. | COMPOSITIONS AND METHODS FOR INCREASING THE EFFICACY OF CELL CULTURES USED IN FOOD PRODUCTION |
| CN111566124A (zh) | 2017-10-25 | 2020-08-21 | 诺华股份有限公司 | 制备表达嵌合抗原受体的细胞的方法 |
| AU2019242912B2 (en) | 2018-03-28 | 2025-07-17 | Board Of Regents, The University Of Texas System | Identification of epigenetic alterations in DNA isolated from exosomes |
| SG11202101825QA (en) | 2018-08-31 | 2021-03-30 | Novartis Ag | Methods of making chimeric antigen receptor-expressing cells |
| WO2020047449A2 (en) | 2018-08-31 | 2020-03-05 | Novartis Ag | Methods of making chimeric antigen receptor-expressing cells |
| CA3109063A1 (en) * | 2018-09-06 | 2020-03-12 | The Board Of Regents Of The University Of Texas System | Telomerase holoenzyme complex and methods of use thereof |
| JP7653146B2 (ja) | 2018-10-02 | 2025-03-28 | ステムオン インコーポレーテッド | 細胞のテロメアを伸長させる方法 |
| US20220073901A1 (en) * | 2018-10-02 | 2022-03-10 | Stemon Inc. | Composition for extending telomere of cell and preparation method therefor |
| KR102209234B1 (ko) * | 2018-10-02 | 2021-02-01 | 주식회사 스템온 | 세포의 텔로미어를 신장시키는 방법 |
| JP2022519718A (ja) * | 2019-02-08 | 2022-03-24 | ボード オブ リージェンツ,ザ ユニバーシティ オブ テキサス システム | 加齢および加齢性臓器不全に関連する疾患の処置のためのテロメラーゼ含有エキソソーム |
| US20220168389A1 (en) | 2019-04-12 | 2022-06-02 | Novartis Ag | Methods of making chimeric antigen receptor-expressing cells |
| CN114364392B (zh) * | 2019-05-02 | 2025-12-16 | 德克萨斯大学系统董事会 | 涉及tert激活治疗剂的方法和组合物 |
| EP3997059A4 (en) | 2019-07-03 | 2023-12-13 | Factor Bioscience Inc. | CATIONIC LIPIDS AND THEIR USES |
| US10501404B1 (en) | 2019-07-30 | 2019-12-10 | Factor Bioscience Inc. | Cationic lipids and transfection methods |
| AR120566A1 (es) | 2019-11-26 | 2022-02-23 | Novartis Ag | Receptores de antígeno quiméricos y sus usos |
| WO2021142355A1 (en) * | 2020-01-10 | 2021-07-15 | Andranik Andrew Aprikyan | Nanoparticles for expression of genes of interest and/or regulation of signaling pathways |
| WO2021167879A1 (en) * | 2020-02-17 | 2021-08-26 | Spinalcyte, Llc | Telomere length modulation using fibroblasts |
| KR20220147109A (ko) | 2020-02-27 | 2022-11-02 | 노파르티스 아게 | 키메라 항원 수용체 발현 세포의 제조 방법 |
| CN112063601B (zh) * | 2020-09-22 | 2023-06-02 | 浙江愈方生物科技有限公司 | 一种灭活性端粒酶、具有其的腺病毒和人造mRNA及应用 |
| CA3206970A1 (en) * | 2020-12-29 | 2022-07-07 | Rejuvenation Technologies Inc. | Compositions and methods for delivery of rna |
| IL307319A (en) * | 2021-03-31 | 2023-11-01 | Rejuvenation Tech Inc | Compositions and methods for delivery of rna |
| CN115678904B (zh) * | 2021-07-22 | 2025-12-09 | 刘小川 | 一种突变的人端粒酶rna基因及其在预防和治疗泛癌种中的应用 |
| KR20250067174A (ko) | 2022-09-15 | 2025-05-14 | 노파르티스 아게 | 키메라 항원 수용체 요법을 사용한 자가면역 장애의 치료 |
| CN117530952A (zh) * | 2023-07-19 | 2024-02-09 | 南京医科大学 | 一种囊胚期移植恢复端粒长度的动物模型构建方法及用途 |
| EP4644561A1 (en) * | 2024-05-03 | 2025-11-05 | Hochschule für Technik und Wirtschaft (HTW) Berlin | Optical, cell-based, high-throughput capable method for the determination of telomere length and dynamics in yeast |
Family Cites Families (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5686306A (en) | 1992-05-13 | 1997-11-11 | Board Of Regents, The University Of Texas System | Methods and reagents for lengthening telomeres |
| US5583016A (en) | 1994-07-07 | 1996-12-10 | Geron Corporation | Mammalian telomerase |
| US5770422A (en) | 1996-07-08 | 1998-06-23 | The Regents Of The University Of California | Human telomerase |
| US6093809A (en) | 1996-10-01 | 2000-07-25 | University Technology Corporation | Telomerase |
| US6610839B1 (en) | 1997-08-14 | 2003-08-26 | Geron Corporation | Promoter for telomerase reverse transcriptase |
| IL129222A0 (en) | 1996-10-01 | 2000-02-17 | Geron Corp | Telomerase reverse transcriptase |
| US8323975B2 (en) | 2002-01-04 | 2012-12-04 | The Board Of Trustees Of The Leland Stanford Junior University | Telomere-encoding synthetic DNA nanocircles, and their use for the elongation of telomere repeats |
| US7897752B2 (en) | 2002-02-20 | 2011-03-01 | Sirna Therapeutics, Inc. | RNA interference mediated inhibition of telomerase gene expression using short interfering nucleic acid (siNA) |
| NZ545516A (en) | 2003-09-09 | 2009-06-26 | Geron Corp | Modified oligonucleotides for telomerase inhibition |
| DE102004035227A1 (de) * | 2004-07-21 | 2006-02-16 | Curevac Gmbh | mRNA-Gemisch zur Vakzinierung gegen Tumorerkrankungen |
| EP4174179B1 (en) | 2005-08-23 | 2025-05-07 | The Trustees of the University of Pennsylvania | Rna containing modified nucleosides and methods of use thereof |
| US9012219B2 (en) * | 2005-08-23 | 2015-04-21 | The Trustees Of The University Of Pennsylvania | RNA preparations comprising purified modified RNA for reprogramming cells |
| US20090032427A1 (en) | 2005-09-29 | 2009-02-05 | Nektar Therapeutics | Receptacles and Kits, Such as for Dry Powder Packaging |
| GB0720486D0 (en) | 2007-10-19 | 2007-11-28 | Univ Edinburgh | Cationic lipids |
| WO2010036813A1 (en) | 2008-09-24 | 2010-04-01 | University Of South Florida | Materials and methods for preventing or treating neurodegenerative conditions associated with abeta peptide accumulation |
| LT3287525T (lt) | 2009-12-07 | 2020-02-10 | The Trustees Of The University Of Pennsylvania | Rnr preparatai, apimantys išgrynintą modifikuotą rnr, skirti ląstelių reprogramavimui |
| RU2443777C2 (ru) * | 2010-03-24 | 2012-02-27 | Учреждение Российской академии медицинских наук Научно-исследовательский институт клинической иммунологии Сибирского отделения РАМН | Способ одномоментного определения длины теломер и количества делений популяции пролиферирующих клеток in vitro |
| CA3122219A1 (en) * | 2010-04-16 | 2011-10-20 | The Children's Hospital Corporation | Sustained polypeptide expression from synthetic, modified rnas and uses thereof |
| US20120177611A1 (en) | 2010-07-15 | 2012-07-12 | Blau Helen M | Elastic substrates and methods of use in cell manipulation and culture |
| CN102433297A (zh) * | 2011-10-14 | 2012-05-02 | 黄必录 | 延伸成体多能干细胞端粒的方法 |
| US8497124B2 (en) | 2011-12-05 | 2013-07-30 | Factor Bioscience Inc. | Methods and products for reprogramming cells to a less differentiated state |
| CN111893140A (zh) | 2011-12-05 | 2020-11-06 | 菲克特生物科学股份有限公司 | 用于转染细胞的方法和产品 |
| DE12858350T1 (de) | 2011-12-16 | 2021-10-07 | Modernatx, Inc. | Modifizierte mrna zusammensetzungen |
| HUE056638T2 (hu) | 2013-02-22 | 2022-02-28 | Univ Leland Stanford Junior | Telomer kiterjesztéssel kapcsolatos gyógyászati alkalmazás |
| JP6123561B2 (ja) | 2013-08-08 | 2017-05-10 | ソニー株式会社 | 発光素子及びその製造方法、並びに、表示装置 |
-
2014
- 2014-02-22 HU HUE14754545A patent/HUE056638T2/hu unknown
- 2014-02-22 EP EP21200777.7A patent/EP3988112B1/en active Active
- 2014-02-22 ES ES14754545T patent/ES2901402T3/es active Active
- 2014-02-22 CA CA2902237A patent/CA2902237C/en active Active
- 2014-02-22 RS RS20220007A patent/RS62824B1/sr unknown
- 2014-02-22 HK HK16106812.5A patent/HK1218934A1/zh unknown
- 2014-02-22 PL PL14754545T patent/PL2959005T3/pl unknown
- 2014-02-22 CN CN201480021010.1A patent/CN105164269A/zh active Pending
- 2014-02-22 EP EP14754545.3A patent/EP2959005B1/en active Active
- 2014-02-22 ES ES21200777T patent/ES3047667T3/es active Active
- 2014-02-22 FI FIEP14754545.3T patent/FI2959005T3/fi active
- 2014-02-22 JP JP2015559027A patent/JP2016514953A/ja active Pending
- 2014-02-22 HR HRP20211842TT patent/HRP20211842T1/hr unknown
- 2014-02-22 CN CN202410035855.1A patent/CN117838716A/zh active Pending
- 2014-02-22 RU RU2022101438A patent/RU2022101438A/ru unknown
- 2014-02-22 IL IL240680A patent/IL240680B2/en unknown
- 2014-02-22 LT LTEPPCT/US2014/017867T patent/LT2959005T/lt unknown
- 2014-02-22 WO PCT/US2014/017867 patent/WO2014130909A1/en not_active Ceased
- 2014-02-22 DK DK14754545.3T patent/DK2959005T3/da active
- 2014-02-22 SI SI201431929T patent/SI2959005T1/sl unknown
- 2014-02-22 AU AU2014218667A patent/AU2014218667A1/en not_active Abandoned
- 2014-02-22 US US14/187,265 patent/US10525075B2/en active Active
- 2014-02-22 US US14/187,264 patent/US20140242154A1/en not_active Abandoned
- 2014-02-22 CN CN202510410957.1A patent/CN120241975A/zh active Pending
- 2014-02-22 IL IL296870A patent/IL296870A/en unknown
- 2014-02-22 RU RU2015140125A patent/RU2766120C2/ru not_active Application Discontinuation
- 2014-02-22 PT PT147545453T patent/PT2959005T/pt unknown
-
2019
- 2019-07-16 JP JP2019131040A patent/JP7103653B2/ja active Active
-
2020
- 2020-01-06 US US16/735,681 patent/US11007210B2/en active Active
- 2020-01-06 US US16/735,683 patent/US11872243B2/en active Active
- 2020-01-06 US US16/735,684 patent/US12053483B2/en active Active
-
2021
- 2021-12-28 CY CY20211101135T patent/CY1125092T1/el unknown
-
2022
- 2022-06-30 JP JP2022105849A patent/JP7486836B2/ja active Active
-
2024
- 2024-04-17 US US18/637,899 patent/US20240277752A1/en active Pending
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| SI2959005T1 (sl) | Medicinska uporaba v zvezi z ekstenzijo telomera | |
| PL2922514T3 (pl) | Dwupromieniowy interfejs dla pacjenta | |
| AU357213S (en) | Patient interface | |
| AU353287S (en) | Patient interface | |
| AU353289S (en) | Patient interface | |
| EP2896352A4 (en) | ENDOSCOPE | |
| EP2950702A4 (en) | Borescope | |
| EP2870909A4 (en) | ENDOSCOPE | |
| EP2974647A4 (en) | ENDOSCOPE | |
| GB2510497B (en) | Catheter | |
| SG11201508879XA (en) | Skin cleansing composition | |
| GB201405503D0 (en) | Novel Use | |
| EP2942002A4 (en) | ENDOSCOPE | |
| PL2777671T3 (pl) | Stół dla pacjenta | |
| EP2878254A4 (en) | ENDOSCOPE | |
| SG11201508529RA (en) | Skin cleansing composition | |
| ZA201504604B (en) | Skin care composition | |
| PL2862502T3 (pl) | Endoskop | |
| EP2893865A4 (en) | ENDOSCOPE | |
| IL233698B (en) | A catheter of multiple shapes | |
| EP2989991A4 (en) | Borescope | |
| PL2818093T3 (pl) | Endoskop | |
| SG2013002829A (en) | Endoscope | |
| GB201307872D0 (en) | Medical use | |
| GB201300324D0 (en) | Improvements to letter-plates |