PL2902384T3 - Postać chlorowodorku iwabradyny - Google Patents
Postać chlorowodorku iwabradynyInfo
- Publication number
- PL2902384T3 PL2902384T3 PL15151073T PL15151073T PL2902384T3 PL 2902384 T3 PL2902384 T3 PL 2902384T3 PL 15151073 T PL15151073 T PL 15151073T PL 15151073 T PL15151073 T PL 15151073T PL 2902384 T3 PL2902384 T3 PL 2902384T3
- Authority
- PL
- Poland
- Prior art keywords
- ivabradine hydrochloride
- ivabradine
- hydrochloride
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D223/16—Benzazepines; Hydrogenated benzazepines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Cardiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Vascular Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Urology & Nephrology (AREA)
- Pharmacology & Pharmacy (AREA)
- Heart & Thoracic Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SI201000057 | 2010-02-12 | ||
EP11702672A EP2534135A2 (en) | 2010-02-12 | 2011-02-11 | Novel forms of ivabradine hydrochloride |
EP15151073.2A EP2902384B1 (en) | 2010-02-12 | 2011-02-11 | Form of ivabradine hydrochloride |
Publications (1)
Publication Number | Publication Date |
---|---|
PL2902384T3 true PL2902384T3 (pl) | 2018-04-30 |
Family
ID=43770633
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PL15151073T PL2902384T3 (pl) | 2010-02-12 | 2011-02-11 | Postać chlorowodorku iwabradyny |
Country Status (6)
Country | Link |
---|---|
EP (2) | EP2534135A2 (pl) |
EA (1) | EA201290772A1 (pl) |
HU (1) | HUE035588T2 (pl) |
PL (1) | PL2902384T3 (pl) |
SI (2) | SI23290A (pl) |
WO (1) | WO2011098582A2 (pl) |
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8900605B2 (en) * | 2010-06-14 | 2014-12-02 | Ratiopharm Gmbh | Solid ivabradine-containing composition |
WO2012025940A1 (en) * | 2010-08-25 | 2012-03-01 | Cadila Healthcare Limited | Polymorphic form of ivabradine hydrochloride and process for preparation thereof |
MX2014001556A (es) | 2011-08-12 | 2014-03-31 | Boehringer Ingelheim Vetmed | Composicion farmaceutica de sabor enmascarado. |
EP2589594A1 (en) * | 2011-11-04 | 2013-05-08 | Urquima S.A. | Ivabradine hydrochloride Form IV |
EP2780327A1 (en) | 2011-11-14 | 2014-09-24 | Cadila Healthcare Limited | Polymorphic forms of ivabradine hydrochloride |
IN2012CH01309A (pl) * | 2012-04-02 | 2015-06-19 | Hetero Research Foundation | |
WO2014024210A2 (en) * | 2012-08-10 | 2014-02-13 | Hetero Research Foundation | Novel polymorphs of doxercalciferol |
WO2014122248A1 (en) | 2013-02-11 | 2014-08-14 | Boehringer Ingelheim Vetmedica Gmbh | Kit-of-parts |
ITMI20130416A1 (it) * | 2013-03-19 | 2014-09-20 | Chemo Res S L | Nuovo polimorfo del cloridrato di ivabradina e metodo per la sua preparazione |
EP2781509B2 (en) | 2013-03-19 | 2023-06-14 | Chemo Research, S.L. | New polymorph of ivabradine hydrochloride and method for its preparation |
WO2015001569A1 (en) * | 2013-07-02 | 2015-01-08 | Genepharm India Private Limited | A solid pharmaceutical composition of ivabradine for oral administration |
CZ305096B6 (cs) | 2013-10-02 | 2015-04-29 | Zentiva, K.S. | Pevná forma Ivabradin hydrochloridu a (S)-mandlové kyseliny a její farmaceutická kompozice |
WO2015001133A1 (en) | 2013-12-12 | 2015-01-08 | Synthon B.V. | Pharmaceutical composition comprising amorphous ivabradine |
WO2015091992A1 (en) * | 2013-12-20 | 2015-06-25 | Synthon B.V. | Pharmaceutical composition comprising amorphous ivabradine |
ES2717715T3 (es) * | 2014-02-14 | 2019-06-24 | Synthon Bv | Composición farmacéutica que comprende polimorfo IV de clorhidrato de ivabradina |
EP3122362A1 (en) * | 2014-03-27 | 2017-02-01 | Laboratorio Chimico Internazionale S.p.A. | Ivabradine adsorbates |
CZ2014478A3 (cs) | 2014-07-10 | 2015-09-16 | Zentiva, K.S. | Pevná forma Ivabradin hydrochloridu a (R)-mandlové kyseliny a její farmaceutická kompozice |
WO2017005844A1 (en) | 2015-07-07 | 2017-01-12 | Janssen Vaccines & Prevention B.V. | Vaccine against rsv |
TR201703066A2 (tr) * | 2017-02-28 | 2018-09-21 | Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi | İvabradi̇ni̇n kati oral farmasöti̇k kompozi̇syonlari |
EP3366282A1 (en) * | 2017-02-28 | 2018-08-29 | Sanovel Ilac Sanayi ve Ticaret A.S. | Solid oral pharmaceutical compositions of ivabradine |
IT202000025312A1 (it) | 2020-10-26 | 2022-04-26 | Cambrex Profarmaco Milano S R L | Processi per la preparazione di polimorfi di ivabradina hcl |
WO2023094048A1 (en) * | 2021-11-24 | 2023-06-01 | Nutrition & Biosciences Usa 1, Llc | Process for producing microcrystalline cellulose with reduced nitrite salt content |
Family Cites Families (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2681862B1 (fr) | 1991-09-27 | 1993-11-12 | Adir Cie | Nouvelles (benzocycloalkyl)alkylamines, leur procede de preparation, et les compositions pharmaceutiques qui les contiennent. |
FR2868777B1 (fr) | 2004-04-13 | 2006-05-26 | Servier Lab | Nouveau procede de synthese de l'ivabradine et de ses sels d'addition a un acide pharmaceutiquement acceptable |
FR2868776B1 (fr) | 2004-04-13 | 2008-04-18 | Servier Lab | Nouveau procede de synthese de derives de la 1,3-dihydro- 2h-3-benzazepin-2-one, et application a la synthese de l'ivabradine et de ses sels d'addition a un acide pharmaceutiquement acceptable |
FR2868775B1 (fr) | 2004-04-13 | 2008-04-11 | Servier Lab | Nouveau procede de synthese de derives de la 1,3,4,5- tetrahydro-2h-3-benzazepin-2-one, et application a la synthese de l'ivabradine et de ses sels d'addition a un acide pharmaceutiquement acceptable |
FR2870537A1 (fr) | 2004-05-19 | 2005-11-25 | Servier Lab | Nouveau procede de synthese du (1s)-4,5-dimethoxy-1-(methyl aminomethyl-)-benzocyclobutane et de ses sels d'addition, et application a la synthese de l'ivabradine et de ses sels d'addition a un acide pharmaceutiquement acceptable |
FR2882555B1 (fr) | 2005-02-28 | 2007-05-04 | Servier Lab | Forme cristalline gamma du chlorhydrate de l'ivabradine, son procede de preparation, et les compositions pharmaceutiques qui la contiennent |
FR2882553B1 (fr) | 2005-02-28 | 2007-05-04 | Servier Lab | Forme cristalline beta du chlorhydrate de l'ivabradine, son procede de preparation, et les compositions pharmaceutiques qui la contiennent |
FR2882554B1 (fr) | 2005-02-28 | 2007-05-04 | Servier Lab | Forme critalline beta d du chlorhydrate de l'ivabradine, son procede de preparation, et les compositions pharmaceutiques qui la contiennent |
FR2882556B1 (fr) | 2005-02-28 | 2007-05-04 | Servier Lab | Forme cristalline gamma d du chlorhydrate de l'ivabradine, son procede de preparation, et les compositions pharmaceutiques qui la contiennent |
FR2891826B1 (fr) | 2005-10-11 | 2007-12-28 | Servier Lab | Forme cristalline 6 du chlorhydrate de l'ivabradine, son procede de preparation et les compositions pharmaceutiques qui la contiennent |
FR2891827B1 (fr) | 2005-10-11 | 2007-12-28 | Servier Lab | Forme cristalline deltad du chlorhydrate de l'ivabradine, son procede de preparation, et les compositions pharmaceutiques qui la contiennent |
ES2381771T3 (es) | 2006-11-30 | 2012-05-31 | Cadila Healthcare Limited | Procedimiento para la preparación de hidrocloruro de ivabradina |
WO2008125006A1 (fr) | 2007-04-12 | 2008-10-23 | Utopharm (Shanghai) Co., Ltd | Procédés de préparation du chlorhydrate d'ivabradine et de sa forme cristalline stable |
EP2471780B1 (en) | 2007-05-30 | 2014-11-26 | Ind-Swift Laboratories Limited | Crystalline Ivabradine Oxalate Salts and Polymorphs Thereof |
CN101434552B (zh) | 2007-11-16 | 2012-05-23 | 江苏恒瑞医药股份有限公司 | 4,5-二甲氧基-1-(甲基氨基甲基)-苯并环丁烷的拆分 |
CN101544605A (zh) | 2008-03-24 | 2009-09-30 | 北京深蓝海生物医药科技有限公司 | 伊伐布雷定及其药学上可接受的加成盐的制备方法 |
CN101343249A (zh) | 2008-06-10 | 2009-01-14 | 上海医药工业研究院 | 3-(3-氯丙基)-7,8-二甲氧基-1,3-二氢-2h-3-苯并氮杂-2-酮的制备方法 |
FR2932800B1 (fr) | 2008-06-20 | 2015-02-20 | Servier Lab | Nouveau procede de synthese de la 7,8-dimethoxy-1,3-dihydro- 2h-3-benzazepin-2-one, et application a la synthese de l'ivabradine et de ses sels d'addition a un acide pharmaceutiquement acceptable |
FR2933975B1 (fr) | 2008-07-17 | 2011-02-18 | Servier Lab | Nouveau procede de preparation de benzocyclobutenes fonctionnalises,et application a la synthese de l'ivabradine et de ses sels d'addition a un acide pharmaceutiquement acceptable. |
-
2011
- 2011-02-11 EA EA201290772A patent/EA201290772A1/ru unknown
- 2011-02-11 SI SI201100042A patent/SI23290A/sl not_active IP Right Cessation
- 2011-02-11 EP EP11702672A patent/EP2534135A2/en not_active Withdrawn
- 2011-02-11 WO PCT/EP2011/052068 patent/WO2011098582A2/en active Application Filing
- 2011-02-11 HU HUE15151073A patent/HUE035588T2/en unknown
- 2011-02-11 SI SI201131384T patent/SI2902384T1/en unknown
- 2011-02-11 PL PL15151073T patent/PL2902384T3/pl unknown
- 2011-02-11 EP EP15151073.2A patent/EP2902384B1/en active Active
Also Published As
Publication number | Publication date |
---|---|
EA201290772A1 (ru) | 2013-02-28 |
SI2902384T1 (en) | 2018-03-30 |
HUE035588T2 (en) | 2018-05-28 |
WO2011098582A2 (en) | 2011-08-18 |
SI23290A (sl) | 2011-08-31 |
EP2902384A1 (en) | 2015-08-05 |
WO2011098582A3 (en) | 2012-03-01 |
EP2534135A2 (en) | 2012-12-19 |
EP2902384B1 (en) | 2017-11-08 |
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