PL2806892T3 - Połączone terapeutyczne zastosowanie przeciwciał i endoglikozydaz - Google Patents

Połączone terapeutyczne zastosowanie przeciwciał i endoglikozydaz

Info

Publication number
PL2806892T3
PL2806892T3 PL13701871T PL13701871T PL2806892T3 PL 2806892 T3 PL2806892 T3 PL 2806892T3 PL 13701871 T PL13701871 T PL 13701871T PL 13701871 T PL13701871 T PL 13701871T PL 2806892 T3 PL2806892 T3 PL 2806892T3
Authority
PL
Poland
Prior art keywords
endoglycosidases
antibodies
therapeutic use
combined therapeutic
combined
Prior art date
Application number
PL13701871T
Other languages
English (en)
Inventor
Matthew David Max Crispin
Christopher Neil SCANLAN
Original Assignee
Immago Biosystems Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Immago Biosystems Ltd filed Critical Immago Biosystems Ltd
Publication of PL2806892T3 publication Critical patent/PL2806892T3/pl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46Hydrolases (3)
    • A61K38/47Hydrolases (3) acting on glycosyl compounds (3.2), e.g. cellulases, lactases
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/39558Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/40Immunoglobulins specific features characterized by post-translational modification
    • C07K2317/41Glycosylation, sialylation, or fucosylation
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y302/00Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01096Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase (3.2.1.96)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Biomedical Technology (AREA)
  • Communicable Diseases (AREA)
  • Hematology (AREA)
  • Reproductive Health (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
PL13701871T 2012-01-26 2013-01-25 Połączone terapeutyczne zastosowanie przeciwciał i endoglikozydaz PL2806892T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB201201314A GB201201314D0 (en) 2012-01-26 2012-01-26 Composition
EP13701871.9A EP2806892B1 (en) 2012-01-26 2013-01-25 Combined therapeutic use of antibodies and endoglycosidases
PCT/GB2013/050164 WO2013110946A1 (en) 2012-01-26 2013-01-25 Combined therapeutic use of antibodies and endoglycosidases

Publications (1)

Publication Number Publication Date
PL2806892T3 true PL2806892T3 (pl) 2019-09-30

Family

ID=45840985

Family Applications (1)

Application Number Title Priority Date Filing Date
PL13701871T PL2806892T3 (pl) 2012-01-26 2013-01-25 Połączone terapeutyczne zastosowanie przeciwciał i endoglikozydaz

Country Status (17)

Country Link
US (4) US20150125443A1 (pl)
EP (1) EP2806892B1 (pl)
JP (1) JP6249962B2 (pl)
CN (2) CN108619509A (pl)
CY (1) CY1122060T1 (pl)
DK (1) DK2806892T3 (pl)
ES (1) ES2728290T3 (pl)
GB (1) GB201201314D0 (pl)
HR (1) HRP20191022T1 (pl)
HU (1) HUE044632T2 (pl)
IN (1) IN2014DN06722A (pl)
LT (1) LT2806892T (pl)
PL (1) PL2806892T3 (pl)
PT (1) PT2806892T (pl)
SI (1) SI2806892T1 (pl)
TR (1) TR201908367T4 (pl)
WO (1) WO2013110946A1 (pl)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11377485B2 (en) 2009-12-02 2022-07-05 Academia Sinica Methods for modifying human antibodies by glycan engineering
US10087236B2 (en) 2009-12-02 2018-10-02 Academia Sinica Methods for modifying human antibodies by glycan engineering
JP6486368B2 (ja) 2013-09-06 2019-03-20 アカデミア シニカAcademia Sinica 改変されたグリコシル基を含む糖脂質を用いたヒトiNKT細胞の活性化
GB201318490D0 (en) * 2013-10-18 2013-12-04 Genovis Ab Method
JP6894239B2 (ja) 2014-05-27 2021-06-30 アカデミア シニカAcademia Sinica 増強された抗体の有効性のための普遍的グリコフォームに関する組成物および方法
WO2015184002A1 (en) 2014-05-27 2015-12-03 Academia Sinica Anti-her2 glycoantibodies and uses thereof
TWI670078B (zh) 2014-05-27 2019-09-01 中央研究院 抗cd20醣抗體及其用途
AU2015267044A1 (en) 2014-05-28 2016-12-15 Academia Sinica Anti-TNF-alpha glycoantibodies and uses thereof
GB201413240D0 (en) * 2014-07-25 2014-09-10 Hansa Medical Ab Method
GB201502306D0 (en) 2015-02-12 2015-04-01 Hansa Medical Ab Protein
GB201502305D0 (en) 2015-02-12 2015-04-01 Hansa Medical Ab Protein
JP6752203B2 (ja) * 2015-07-16 2020-09-09 第一三共株式会社 新規EndoS変異酵素
AU2017212484C1 (en) * 2016-01-27 2020-11-05 Medimmune, Llc Methods for preparing antibodies with a defined glycosylation pattern
US10434141B2 (en) 2016-05-31 2019-10-08 Abcentra, Llc Methods for treating systemic lupus erythematosus with an anti-apolipoprotein B antibody
US10858422B2 (en) 2016-05-31 2020-12-08 Abcentra, Llc Methods for treating systemic lupus erythematosus with an anti-apolipoprotein B antibody
JP2017226648A (ja) * 2016-06-17 2017-12-28 SonoCore株式会社 分子標的薬バブルおよび分子標的薬バブルの製造方法
US20210228738A1 (en) * 2017-07-17 2021-07-29 INSERM (Institut National de la Santé et de la Recherche Médicale) Compositions and methods for increasing or enhancing transduction of gene therapy vectors and for removing or reducing immunoglobulins
CN110151987B (zh) * 2018-02-11 2023-10-13 汕头大学医学院 对称IgG及其组合物在制备治疗及预防肿瘤的药物中的用途
US20230049145A1 (en) * 2019-12-12 2023-02-16 Fresenius Kabi Deutschland Gmbh Glycosylated polypeptides
GB202007431D0 (en) 2020-05-19 2020-07-01 Hansa Biopharma AB Cysteine protease
CN115066261A (zh) * 2020-06-05 2022-09-16 上海宝济药业有限公司 一种酶和病毒的药物组合及其应用
CN113769058A (zh) * 2020-06-10 2021-12-10 上海宝济药业有限公司 一种药物组合及其应用
WO2022057942A1 (zh) * 2020-09-21 2022-03-24 上海宝济药业有限公司 一种药物组合及其应用
JPWO2022124096A1 (pl) * 2020-12-11 2022-06-16
EP4079848A1 (en) 2021-04-22 2022-10-26 Genovis Ab Immunoglobulin cleaving enzyme

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4366241A (en) 1980-08-07 1982-12-28 Syva Company Concentrating zone method in heterogeneous immunoassays
US20040136986A1 (en) 1997-10-31 2004-07-15 Genentech, Inc. Methods and compositions comprising glycoprotein glycoforms
DE69840412D1 (de) 1997-10-31 2009-02-12 Genentech Inc Methoden und zusammensetzungen bestehend aus glykoprotein-glykoformen
BR0213761A (pt) 2001-10-25 2005-04-12 Genentech Inc Composições, preparação farmacêutica, artigo industrializado, método de tratamento de mamìferos, célula hospedeira, método para a produção de uma glicoproteìna e uso da composição
GB0130228D0 (en) 2001-12-18 2002-02-06 Hansa Medica Ab Protein
EP1485492B1 (en) 2002-03-19 2011-12-21 Stichting Dienst Landbouwkundig Onderzoek Gntiii (udp-n-acetylglucosamine:beta-d mannoside beta(1,4)-n-acetylglucosaminyltransferase iii) expression in plants
EP1523485B1 (en) 2002-07-15 2007-02-14 Janssen Pharmaceutica N.V. 3-furanyl analogs of toxoflavine as kinase inhibitors
GB0624874D0 (en) * 2006-12-13 2007-01-24 Hansa Medical Ab Treatment
CN102584989B (zh) * 2007-09-14 2015-05-13 季诺维斯公司 用于解离Fcgamma-受体-IgG复合物及纯化与检测IgG的方法和试剂盒
JP6894239B2 (ja) * 2014-05-27 2021-06-30 アカデミア シニカAcademia Sinica 増強された抗体の有効性のための普遍的グリコフォームに関する組成物および方法

Also Published As

Publication number Publication date
US20170274070A1 (en) 2017-09-28
EP2806892A1 (en) 2014-12-03
CN104519911B (zh) 2018-07-17
HRP20191022T1 (hr) 2019-09-06
CY1122060T1 (el) 2020-11-25
GB201201314D0 (en) 2012-03-07
IN2014DN06722A (pl) 2015-05-22
PT2806892T (pt) 2019-06-17
TR201908367T4 (tr) 2019-06-21
EP2806892B1 (en) 2019-03-06
CN104519911A (zh) 2015-04-15
HUE044632T2 (hu) 2019-11-28
JP6249962B2 (ja) 2017-12-20
CN108619509A (zh) 2018-10-09
JP2015511223A (ja) 2015-04-16
US20200345844A1 (en) 2020-11-05
LT2806892T (lt) 2019-07-25
DK2806892T3 (da) 2019-06-11
ES2728290T3 (es) 2019-10-23
US20230398212A1 (en) 2023-12-14
US20150125443A1 (en) 2015-05-07
SI2806892T1 (sl) 2019-08-30
WO2013110946A1 (en) 2013-08-01

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