PL2755973T3 - Podstawione 4,5,6,7-tetrahydro-1H-pirazolo[4,3-c]pirydyny, ich zastosowanie jako lek i preparaty farmaceutyczne je zawierające - Google Patents

Podstawione 4,5,6,7-tetrahydro-1H-pirazolo[4,3-c]pirydyny, ich zastosowanie jako lek i preparaty farmaceutyczne je zawierające

Info

Publication number
PL2755973T3
PL2755973T3 PL11757858T PL11757858T PL2755973T3 PL 2755973 T3 PL2755973 T3 PL 2755973T3 PL 11757858 T PL11757858 T PL 11757858T PL 11757858 T PL11757858 T PL 11757858T PL 2755973 T3 PL2755973 T3 PL 2755973T3
Authority
PL
Poland
Prior art keywords
pyrazolo
pyridines
tetrahydro
medicament
substituted
Prior art date
Application number
PL11757858T
Other languages
English (en)
Inventor
Laurent Bialy
Katrin Lorenz
Klaus Wirth
Klaus Steinmeyer
Gerhard Hessler
Josef Pernerstorfer
Joachim Brendel
Original Assignee
Sanofi Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Sa filed Critical Sanofi Sa
Publication of PL2755973T3 publication Critical patent/PL2755973T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/16—Central respiratory analeptics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/18—Bridged systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pulmonology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyridine Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
PL11757858T 2011-09-16 2011-09-16 Podstawione 4,5,6,7-tetrahydro-1H-pirazolo[4,3-c]pirydyny, ich zastosowanie jako lek i preparaty farmaceutyczne je zawierające PL2755973T3 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PCT/EP2011/066061 WO2013037415A1 (en) 2011-09-16 2011-09-16 Substituted 4,5,6,7-tetrahydro-1h-pyrazolo[4,3-c]pyridines, their use as medicament, and pharmaceutical preparations comprising them
EP11757858.3A EP2755973B1 (en) 2011-09-16 2011-09-16 Substituted 4,5,6,7-tetrahydro-1h-pyrazolo[4,3-c]pyridines, their use as medicament, and pharmaceutical preparations comprising them

Publications (1)

Publication Number Publication Date
PL2755973T3 true PL2755973T3 (pl) 2016-04-29

Family

ID=44653324

Family Applications (1)

Application Number Title Priority Date Filing Date
PL11757858T PL2755973T3 (pl) 2011-09-16 2011-09-16 Podstawione 4,5,6,7-tetrahydro-1H-pirazolo[4,3-c]pirydyny, ich zastosowanie jako lek i preparaty farmaceutyczne je zawierające

Country Status (18)

Country Link
US (2) US9127001B2 (pl)
EP (1) EP2755973B1 (pl)
JP (1) JP5957525B2 (pl)
KR (1) KR20140077912A (pl)
CN (1) CN103930421B (pl)
AU (1) AU2011376721B2 (pl)
CA (1) CA2846366A1 (pl)
CY (1) CY1117396T1 (pl)
DK (1) DK2755973T3 (pl)
ES (1) ES2559450T3 (pl)
HR (1) HRP20160049T1 (pl)
HU (1) HUE028378T2 (pl)
IL (1) IL231050A (pl)
PL (1) PL2755973T3 (pl)
PT (1) PT2755973E (pl)
SG (1) SG11201400092VA (pl)
SI (1) SI2755973T1 (pl)
WO (1) WO2013037415A1 (pl)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2755973B1 (en) 2011-09-16 2015-11-04 Sanofi Substituted 4,5,6,7-tetrahydro-1h-pyrazolo[4,3-c]pyridines, their use as medicament, and pharmaceutical preparations comprising them
US9016191B2 (en) 2012-04-20 2015-04-28 Robert S. Krolick Portable baking oven
EP3134406A1 (en) * 2014-04-24 2017-03-01 Dart Neuroscience (Cayman) Ltd Substituted 2,4,5,6-tetrahydropyrrolo[3,4-c]pyrazole and 4,5,6,7-tetrahydro-2h-pyrazolo [4,3-c]pyridine compounds as glyt1 inhibitors
EP3215500A1 (en) 2014-11-05 2017-09-13 Dart NeuroScience (Cayman) Ltd. Substituted azetidinyl compounds as glyt1 inhibitors
WO2016109684A2 (en) 2014-12-30 2016-07-07 Novira Therapeutics, Inc. Derivatives and methods of treating hepatitis b infections
WO2017097671A1 (de) * 2015-12-10 2017-06-15 Bayer Pharma Aktiengesellschaft Substituierte perhydropyrrolo[3,4-c]pyrrol-derivate und ihre verwendung
KR20180088462A (ko) 2015-12-10 2018-08-03 바이엘 파마 악티엔게젤샤프트 수면-관련 호흡기 장애의 치료를 위한 TASK-1 및 TASK-2 채널의 차단제로서의 2-페닐-3-(피페라지노메틸)이미다조[1,2-a]피리딘 유도체
JOP20190005A1 (ar) * 2016-07-20 2019-01-20 Bayer Ag مركبات ديازاهيترو ثنائية الحلقة مستبدلة واستخداماتها
JOP20190284A1 (ar) 2017-06-14 2019-12-11 Bayer Pharma AG مركبات إيميدازوبيريميدين مستبدلة بديازا ثنائي الحلقة واستخدامها للمعالجة من اضطرابات التنفس
WO2018227427A1 (en) * 2017-06-14 2018-12-20 Bayer Aktiengesellschaft Substituted bridged diazepane derivatives and use thereof
US20200308582A1 (en) * 2017-10-12 2020-10-01 Universität Heidelberg Kcnk3-based gene therapy of cardiac arrhythmia
WO2023083286A1 (en) 2021-11-12 2023-05-19 Insilico Medicine Ip Limited Small molecule inhibitors of ubiquitin specific protease 1 (usp1) and uses thereof

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK27383A (da) * 1982-02-17 1983-08-18 Lepetit Spa Fremgangsmaade til fremstilling af pyrazol(4,3-c)pyridiner
DE10332685A1 (de) 2003-07-18 2005-02-17 Bayer Healthcare Ag Vorhof-selektiv exprimierte Kaliumkanäle
US7772232B2 (en) * 2004-04-15 2010-08-10 Bristol-Myers Squibb Company Quinazolinyl compounds as inhibitors of potassium channel function
DE102005028845A1 (de) 2005-06-22 2006-12-28 Sanofi-Aventis Deutschland Gmbh Substituierte Heterocyclen, ihre Verwendung als Medikament sowie enthaltende pharmazeutische Zubereitungen
DE102005028862A1 (de) 2005-06-22 2007-01-11 Sanofi-Aventis Deutschland Gmbh Substituierte Heterocyclen, ihre Verwendung als Medikament sowie sie enthaltende pharmazeutische Zubereitungen
KR101390239B1 (ko) 2006-04-27 2014-04-30 사노피-아벤티스 도이칠란트 게엠베하 Ｔａｓｋ-1 및 ｔａｓｋ-3 이온 채널 억제제
US20130178475A1 (en) * 2010-03-17 2013-07-11 Ironwood Pharmaceuticals, Inc. sGC STIMULATORS
EP2755973B1 (en) 2011-09-16 2015-11-04 Sanofi Substituted 4,5,6,7-tetrahydro-1h-pyrazolo[4,3-c]pyridines, their use as medicament, and pharmaceutical preparations comprising them

Also Published As

Publication number Publication date
HK1194740A1 (en) 2014-10-24
HUE028378T2 (hu) 2016-12-28
JP5957525B2 (ja) 2016-07-27
AU2011376721B2 (en) 2017-06-08
IL231050A0 (en) 2014-03-31
US20160060259A1 (en) 2016-03-03
SI2755973T1 (sl) 2016-02-29
KR20140077912A (ko) 2014-06-24
SG11201400092VA (en) 2014-07-30
CA2846366A1 (en) 2013-03-21
IL231050A (en) 2016-06-30
PT2755973E (pt) 2016-02-16
US9127001B2 (en) 2015-09-08
DK2755973T3 (en) 2016-01-25
CN103930421A (zh) 2014-07-16
ES2559450T3 (es) 2016-02-12
EP2755973B1 (en) 2015-11-04
US20140330009A1 (en) 2014-11-06
CN103930421B (zh) 2016-06-29
WO2013037415A1 (en) 2013-03-21
CY1117396T1 (el) 2017-04-26
EP2755973A1 (en) 2014-07-23
HRP20160049T1 (hr) 2016-02-12
JP2014526479A (ja) 2014-10-06
US9598410B2 (en) 2017-03-21
AU2011376721A1 (en) 2014-04-03

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