PL2744831T3 - Białko fuzyjne transferryna-tumstatyna oraz sposoby jego wytwarzania i stosowania - Google Patents

Białko fuzyjne transferryna-tumstatyna oraz sposoby jego wytwarzania i stosowania

Info

Publication number
PL2744831T3
PL2744831T3 PL12824616T PL12824616T PL2744831T3 PL 2744831 T3 PL2744831 T3 PL 2744831T3 PL 12824616 T PL12824616 T PL 12824616T PL 12824616 T PL12824616 T PL 12824616T PL 2744831 T3 PL2744831 T3 PL 2744831T3
Authority
PL
Poland
Prior art keywords
transferrin
producing
methods
same
fusion protein
Prior art date
Application number
PL12824616T
Other languages
English (en)
Polish (pl)
Inventor
Uday B. Kompella
Robert I. SCHEINMAN
Puneet Tyagi
Original Assignee
The Regents Of The University Of Colorado, A Body Corporate
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by The Regents Of The University Of Colorado, A Body Corporate filed Critical The Regents Of The University Of Colorado, A Body Corporate
Publication of PL2744831T3 publication Critical patent/PL2744831T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/79—Transferrins, e.g. lactoferrins, ovotransferrins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/20—Fusion polypeptide containing a tag with affinity for a non-protein ligand
    • C07K2319/21—Fusion polypeptide containing a tag with affinity for a non-protein ligand containing a His-tag
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/60—Fusion polypeptide containing spectroscopic/fluorescent detection, e.g. green fluorescent protein [GFP]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
PL12824616T 2011-08-17 2012-08-15 Białko fuzyjne transferryna-tumstatyna oraz sposoby jego wytwarzania i stosowania PL2744831T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161524508P 2011-08-17 2011-08-17
EP12824616.2A EP2744831B1 (en) 2011-08-17 2012-08-15 Transferrin-tumstatin fusion protein and methods for producing and using the same
PCT/US2012/051013 WO2013025846A2 (en) 2011-08-17 2012-08-15 Transferrin-tumstatin fusion protein and methods for producing and using the same

Publications (1)

Publication Number Publication Date
PL2744831T3 true PL2744831T3 (pl) 2018-05-30

Family

ID=47715692

Family Applications (1)

Application Number Title Priority Date Filing Date
PL12824616T PL2744831T3 (pl) 2011-08-17 2012-08-15 Białko fuzyjne transferryna-tumstatyna oraz sposoby jego wytwarzania i stosowania

Country Status (15)

Country Link
US (1) US9290562B2 (enrdf_load_stackoverflow)
EP (1) EP2744831B1 (enrdf_load_stackoverflow)
JP (1) JP6073888B2 (enrdf_load_stackoverflow)
CN (2) CN110105453A (enrdf_load_stackoverflow)
AU (1) AU2012296588B2 (enrdf_load_stackoverflow)
BR (1) BR112014008680A2 (enrdf_load_stackoverflow)
CA (1) CA2849015C (enrdf_load_stackoverflow)
DK (1) DK2744831T3 (enrdf_load_stackoverflow)
ES (1) ES2659161T3 (enrdf_load_stackoverflow)
NO (1) NO2820418T3 (enrdf_load_stackoverflow)
PL (1) PL2744831T3 (enrdf_load_stackoverflow)
PT (1) PT2744831T (enrdf_load_stackoverflow)
SI (1) SI2744831T1 (enrdf_load_stackoverflow)
TR (1) TR201802686T4 (enrdf_load_stackoverflow)
WO (1) WO2013025846A2 (enrdf_load_stackoverflow)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2995626B1 (en) * 2013-05-06 2018-07-11 China Pharmaceutical University Bifunctional fusion proteins to inhibit angiogenesis in tumour microenvironment and to activate adaptive immune responses and the genes and uses thereof
JP2016522249A (ja) * 2013-06-20 2016-07-28 ノバルティス アーゲー 脈絡膜血管新生の治療におけるｖｅｇｆアンタゴニストの使用
US11058750B2 (en) * 2015-12-03 2021-07-13 Mor Research Applications Ltd. Compositions and methods for treatment of ocular diseases
KR101818151B1 (ko) 2016-03-25 2018-01-16 한국과학기술원 트렌스페린을 포함하는 허혈성망막병증 예방 및 치료용 조성물
CN109053899B (zh) * 2017-12-22 2021-11-16 湖南远泰生物技术有限公司 一种含人转铁蛋白抗原表位序列的嵌合体抗原受体

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5672683A (en) 1989-09-07 1997-09-30 Alkermes, Inc. Transferrin neuropharmaceutical agent fusion protein
US20050192242A1 (en) 1995-10-11 2005-09-01 Neal Zane C. Therapeutic fusion protein transgenes
EP1086129A1 (en) * 1998-06-17 2001-03-28 Beth Israel Deaconess Medical Center Anti-angiogenic proteins and methods of use thereof
AU3075801A (en) 1999-12-23 2001-07-03 Human Genome Sciences, Inc. Transferrin polynucleotides, polypeptides, and antibodies
KR20040059490A (ko) 2001-08-30 2004-07-05 바이오렉시스 파마슈티칼 코포레이션 변형 트랜스페린 융합 단백질
US8129504B2 (en) * 2001-08-30 2012-03-06 Biorexis Technology, Inc. Oral delivery of modified transferrin fusion proteins
WO2003060071A2 (en) 2001-12-21 2003-07-24 Human Genome Sciences, Inc. Albumin fusion proteins
KR20050002823A (ko) * 2002-02-07 2005-01-10 델타 바이오테크놀로지 리미티드 알부민-융합 쿠니츠 도메인 펩타이드
EP1670428A4 (en) 2003-10-10 2008-03-12 Univ Southern California HYBRID PROTEINS G-CSF-TRANSFERRIN
CN101031287A (zh) * 2004-03-02 2007-09-05 麻省理工学院 纳米细胞药物递送系统
CA2583399A1 (en) 2004-10-14 2006-04-27 Sopherion Therapeutics, Inc. Anti-angiogenic peptides and methods of use thereof
WO2006049983A2 (en) 2004-10-27 2006-05-11 Biorexis Pharmaceutical Corporation Peptide yy modified transferrin fusion proteins
CA2606989A1 (en) * 2005-04-29 2006-11-09 Research Development Foundation Vascular targeting of ocular neovascularization
WO2007087689A1 (en) 2006-02-03 2007-08-09 Crc For Asthma And Airways Ltd A method of modulating cellular activity and agents for use therein
CN101070349B (zh) * 2007-05-22 2010-10-13 山西康宝生物制品股份有限公司 具有选择性杀伤肿瘤新生血管内皮细胞作用的融合蛋白与应用
CN101092452A (zh) * 2007-05-23 2007-12-26 哈尔滨医科大学 肿瘤抑素抗血管生成小分子多肽、融合蛋白及两者制备方法
US7943733B2 (en) * 2007-12-20 2011-05-17 University Of Southern California Spacers to increase the expression of recombinant fusion proteins
CN103732628B (zh) 2011-03-03 2017-06-23 酵活有限公司 多价杂多聚体骨架设计和构建体

Also Published As

Publication number Publication date
CN110105453A (zh) 2019-08-09
BR112014008680A2 (pt) 2017-06-13
WO2013025846A2 (en) 2013-02-21
CA2849015C (en) 2017-08-08
DK2744831T3 (en) 2018-03-05
AU2012296588B2 (en) 2017-07-27
CA2849015A1 (en) 2013-02-21
EP2744831A4 (en) 2015-03-11
ES2659161T3 (es) 2018-03-14
JP2014526890A (ja) 2014-10-09
PT2744831T (pt) 2018-03-05
TR201802686T4 (tr) 2018-03-21
AU2012296588A1 (en) 2014-04-03
EP2744831A2 (en) 2014-06-25
CN103998470A (zh) 2014-08-20
SI2744831T1 (en) 2018-04-30
US9290562B2 (en) 2016-03-22
US20140179612A1 (en) 2014-06-26
JP6073888B2 (ja) 2017-02-01
NO2820418T3 (enrdf_load_stackoverflow) 2018-05-05
WO2013025846A3 (en) 2013-05-02
EP2744831B1 (en) 2017-12-06

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