PL2678000T3 - Stabilizowane granulaty zawierające triazotan glicerolu - Google Patents
Stabilizowane granulaty zawierające triazotan gliceroluInfo
- Publication number
- PL2678000T3 PL2678000T3 PL12707232T PL12707232T PL2678000T3 PL 2678000 T3 PL2678000 T3 PL 2678000T3 PL 12707232 T PL12707232 T PL 12707232T PL 12707232 T PL12707232 T PL 12707232T PL 2678000 T3 PL2678000 T3 PL 2678000T3
- Authority
- PL
- Poland
- Prior art keywords
- granules containing
- glyceryl trinitrate
- containing glyceryl
- stabilized granules
- stabilized
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/143—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
- B65D85/00—Containers, packaging elements or packages, specially adapted for particular articles or materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/03—Containers specially adapted for medical or pharmaceutical purposes for pills or tablets
- A61J1/035—Blister-type containers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
- A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Emergency Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Zoology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Mechanical Engineering (AREA)
- Inorganic Chemistry (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Organic Chemistry (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE102011012491 | 2011-02-25 | ||
EP12707232.0A EP2678000B1 (en) | 2011-02-25 | 2012-02-24 | Stabilized granules containing glyceryl trinitrate |
PCT/EP2012/000803 WO2012113564A1 (en) | 2011-02-25 | 2012-02-24 | Stabilized granules containing glyceryl trinitrate |
Publications (1)
Publication Number | Publication Date |
---|---|
PL2678000T3 true PL2678000T3 (pl) | 2018-08-31 |
Family
ID=45787158
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PL12706778T PL2678006T3 (pl) | 2011-02-25 | 2012-02-24 | Pakowanie stałych preparatów farmaceutycznych zawierających substancję aktywną triazotan glicerolu |
PL12707232T PL2678000T3 (pl) | 2011-02-25 | 2012-02-24 | Stabilizowane granulaty zawierające triazotan glicerolu |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PL12706778T PL2678006T3 (pl) | 2011-02-25 | 2012-02-24 | Pakowanie stałych preparatów farmaceutycznych zawierających substancję aktywną triazotan glicerolu |
Country Status (7)
Country | Link |
---|---|
US (4) | US20130331461A1 (pl) |
EP (3) | EP2678006B1 (pl) |
AU (2) | AU2012219926B2 (pl) |
CA (2) | CA2827714A1 (pl) |
ES (2) | ES2672261T3 (pl) |
PL (2) | PL2678006T3 (pl) |
WO (2) | WO2012113563A1 (pl) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
HUE033092T2 (hu) * | 2012-05-31 | 2017-11-28 | G Pohl-Boskamp Gmbh & Co Kg | Arteriogenezis indukálása nitroglicerinnel mint nitrogén-oxid donorral |
WO2019009927A1 (en) * | 2017-07-06 | 2019-01-10 | Adorus Pharmaceuticals Llc | MIXTURE COMPOSITIONS FOR ORAL ADMINISTRATION AS POWDER AND / OR SUSPENSION WITH RAPID DISSOLUTION |
Family Cites Families (50)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BE632504A (pl) | 1962-05-24 | |||
US3432593A (en) * | 1963-09-18 | 1969-03-11 | Key Pharm Inc | Delayed and sustained release type pharmaceutical preparation |
GB1205019A (en) * | 1966-12-07 | 1970-09-09 | Sterwin Ag | Improvements in or relating to oral dosage forms |
US3789119A (en) * | 1971-06-01 | 1974-01-29 | Parke Davis & Co | Stabilized molded sublingual nitroglycerin tablets |
JPS599539B2 (ja) | 1979-11-13 | 1984-03-03 | 日本化薬株式会社 | ニトログリセリン水溶液及びその製造法 |
CA1163195A (en) | 1980-06-26 | 1984-03-06 | Alec D. Keith | Polymeric diffusion matrix containing a vasodilator |
US4542013A (en) * | 1981-07-08 | 1985-09-17 | Key Pharmaceuticals, Inc. | Trinitroglycerol sustained release vehicles and preparation therefrom |
DE3246081A1 (de) | 1982-12-13 | 1984-06-14 | G. Pohl-Boskamp GmbH & Co Chemisch-pharmazeutische Fabrik, 2214 Hohenlockstedt | Nitroglycerin-spray |
ATE191145T1 (de) | 1987-01-23 | 2000-04-15 | Gen Hospital Corp | Hydralazin zur topischen behandlung von glaukom |
JPH0645538B2 (ja) | 1987-09-30 | 1994-06-15 | 日本化薬株式会社 | ニトログリセリンスプレー剤 |
HU199678B (en) | 1988-07-08 | 1990-03-28 | Egyt Gyogyszervegyeszeti Gyar | Process for producing aerosols containing nitroglicerol |
DE4007705C1 (pl) | 1990-03-10 | 1991-09-26 | G. Pohl-Boskamp Gmbh & Co. Chemisch-Pharmazeutische Fabrik, 2214 Hohenlockstedt, De | |
US5370862A (en) | 1990-06-13 | 1994-12-06 | Schwarz Pharma Ag | Pharmaceutical hydrophilic spray containing nitroglycerin for treating angina |
DE4018919C2 (de) | 1990-06-13 | 1994-08-25 | Sanol Arznei Schwarz Gmbh | Nitroglycerin-Spray |
DE4026072A1 (de) | 1990-08-17 | 1992-02-20 | Sanol Arznei Schwarz Gmbh | Nitroglycerinhaltiger, hydrophiler, waessriger pumpspray |
DE4038203A1 (de) | 1990-11-30 | 1992-06-04 | Kali Chemie Pharma Gmbh | Pharmazeutische spray-zubereitungen mit coronaraktiven wirkstoffen |
US5698589A (en) | 1993-06-01 | 1997-12-16 | International Medical Innovations, Inc. | Water-based topical cream containing nitroglycerin and method of preparation and use thereof |
US5869082A (en) | 1996-04-12 | 1999-02-09 | Flemington Pharmaceutical Corp. | Buccal, non-polar spray for nitroglycerin |
US20010044584A1 (en) | 1997-08-28 | 2001-11-22 | Kensey Kenneth R. | In vivo delivery methods and compositions |
US20030095925A1 (en) | 1997-10-01 | 2003-05-22 | Dugger Harry A. | Buccal, polar and non-polar spray or capsule containing drugs for treating metabolic disorders |
EP1019039B1 (en) * | 1997-10-03 | 2001-12-05 | Warner-Lambert Company | Compressed nitroglycerin tablet and its method of manufacture |
US6796966B2 (en) | 1997-10-15 | 2004-09-28 | Jeffrey E. Thomas | Apparatus, and kits for preventing of alleviating vasoconstriction or vasospasm in a mammal |
AU2479099A (en) | 1998-01-28 | 1999-08-16 | Seatrace Pharmaceuticals, Inc. | Topical vasodilatory gel composition and methods of use and production |
US5989529A (en) | 1998-11-20 | 1999-11-23 | Schering-Plough Healthcare Products, Inc. | Substantive topical composition |
IT1303793B1 (it) * | 1998-11-27 | 2001-02-23 | Promefarm S R L | "composizione farmaceutica comprendente un composto organico donatoredi ossido nitrico (no)" |
US6962691B1 (en) | 1999-05-20 | 2005-11-08 | U & I Pharmaceuticals Ltd. | Topical spray compositions |
RU2174838C2 (ru) | 1999-11-04 | 2001-10-20 | Ивановская государственная медицинская академия | Способ лечения тяжелого бронхообструктивного синдрома у детей раннего возраста |
WO2001043735A1 (en) | 1999-12-15 | 2001-06-21 | Cellegy Pharmaceuticals, Inc. | Nitroglycerin ointment for treatment of pain associated with anal disease |
US6443307B1 (en) * | 2000-01-25 | 2002-09-03 | Michael D. Burridge | Medication dispenser with an internal ejector |
AU4916501A (en) * | 2000-03-14 | 2001-09-24 | Noven Pharmaceuticals, Inc. | Packaging materials for transdermal drug delivery systems |
US6538033B2 (en) | 2000-08-29 | 2003-03-25 | Huntington Medical Research Institutes | Nitric oxide donor compounds |
CA2450762A1 (en) | 2001-06-22 | 2003-01-03 | Pfizer Products Inc. | Pharmaceutical compositions comprising low-solubility and/or acid-sensitive drugs and neutralized acidic polymers |
MXPA04007657A (es) * | 2002-02-08 | 2004-11-10 | Procter & Gamble | Sachet a prueba de ninos. |
US20050095278A1 (en) | 2003-01-14 | 2005-05-05 | Viorel Nicolaescu | Use of nitroglycerin to relieve nocturnal muscle cramps |
US20040228883A1 (en) | 2003-02-21 | 2004-11-18 | Mitchell Karl | Prepackaged aqueous pharmaceutical formulation for the treatment of cardiac conditions containing at least two different active agents and method of formulation |
US20070059346A1 (en) | 2003-07-01 | 2007-03-15 | Todd Maibach | Film comprising therapeutic agents |
US20070053966A1 (en) | 2003-10-17 | 2007-03-08 | Robert Ang | Medicated orthopedic support structures for treatment of damaged musculoskeletal tissue |
US7781226B2 (en) * | 2004-02-27 | 2010-08-24 | The Board Of Regents Of The University Of Texas System | Particle on membrane assay system |
JP2007526316A (ja) | 2004-03-01 | 2007-09-13 | ルーメン セラピューティックス リミテッド ライアビリティ カンパニー | 疾患を処置するための組成物および方法 |
US20080260861A1 (en) | 2004-04-07 | 2008-10-23 | The General Hospital Corporation | Modulating Lymphatic Function |
WO2007081206A1 (en) | 2006-01-09 | 2007-07-19 | Pantarhei Bioscience B.V. | A method of treating an acute vascular disorder |
JP2009534387A (ja) | 2006-04-19 | 2009-09-24 | ノヴァデル ファーマ インコーポレイテッド | 安定な含水アルコール性経口噴霧調剤物および方法 |
US20080311162A1 (en) * | 2007-05-16 | 2008-12-18 | Olivia Darmuzey | Solid form |
CN101229148A (zh) * | 2007-12-28 | 2008-07-30 | 天津医科大学 | 硝酸甘油口腔(舌下)崩解片的制剂及其制备方法 |
DE102008005484A1 (de) | 2008-01-22 | 2009-07-23 | Schaper, Wolfgang, Dr. | Induktion und Förderung der Arteriogenese |
PT2098249E (pt) * | 2008-03-05 | 2013-01-07 | Rivopharm Sa | Veículos para nicorandil com estabilidade melhorada |
DE202008007318U1 (de) | 2008-03-14 | 2008-07-31 | G. Pohl-Boskamp Gmbh & Co. Kg | Langzeitstabile pharmazeutische Zubereitung mit dem Wirkstoff Glyceroltrinitrat |
US20100184870A1 (en) | 2008-03-14 | 2010-07-22 | Rolf Groteluschen | Long-term stable pharmaceutical preparation containing the active ingredient glycerol trinitrate |
US20100016446A1 (en) | 2008-07-21 | 2010-01-21 | Sylvia Gonda | Stable water-based topical pharmaceutical creams and methods of making and using same |
JP2011010865A (ja) | 2009-06-30 | 2011-01-20 | Ikaria Holdings Inc | 肺高血圧の臨床的または超音波心臓検査上の証拠を伴う低酸素性呼吸器不全に罹った満期産およびほぼ満期産の新生児を治療する方法 |
-
2012
- 2012-02-24 EP EP12706778.3A patent/EP2678006B1/en not_active Not-in-force
- 2012-02-24 PL PL12706778T patent/PL2678006T3/pl unknown
- 2012-02-24 AU AU2012219926A patent/AU2012219926B2/en not_active Ceased
- 2012-02-24 WO PCT/EP2012/000802 patent/WO2012113563A1/en active Application Filing
- 2012-02-24 ES ES12707232.0T patent/ES2672261T3/es active Active
- 2012-02-24 ES ES12706778.3T patent/ES2565632T3/es active Active
- 2012-02-24 CA CA2827714A patent/CA2827714A1/en not_active Abandoned
- 2012-02-24 EP EP18159399.7A patent/EP3354259A1/en not_active Withdrawn
- 2012-02-24 US US14/001,018 patent/US20130331461A1/en not_active Abandoned
- 2012-02-24 CA CA2827716A patent/CA2827716C/en active Active
- 2012-02-24 US US14/001,032 patent/US20130327676A1/en not_active Abandoned
- 2012-02-24 WO PCT/EP2012/000803 patent/WO2012113564A1/en active Application Filing
- 2012-02-24 PL PL12707232T patent/PL2678000T3/pl unknown
- 2012-02-24 AU AU2012219925A patent/AU2012219925B2/en not_active Ceased
- 2012-02-24 EP EP12707232.0A patent/EP2678000B1/en active Active
-
2014
- 2014-08-29 US US14/473,415 patent/US9101592B2/en active Active
-
2015
- 2015-07-06 US US14/792,158 patent/US9616023B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
ES2565632T3 (es) | 2016-04-06 |
US9101592B2 (en) | 2015-08-11 |
US20140370109A1 (en) | 2014-12-18 |
AU2012219925A1 (en) | 2013-10-03 |
US20160000711A1 (en) | 2016-01-07 |
CA2827716A1 (en) | 2012-08-30 |
EP2678000A1 (en) | 2014-01-01 |
ES2672261T3 (es) | 2018-06-13 |
EP2678006B1 (en) | 2015-12-30 |
CA2827714A1 (en) | 2012-08-30 |
WO2012113563A1 (en) | 2012-08-30 |
WO2012113564A1 (en) | 2012-08-30 |
EP2678006A1 (en) | 2014-01-01 |
AU2012219925B2 (en) | 2017-02-23 |
EP2678000B1 (en) | 2018-03-07 |
US9616023B2 (en) | 2017-04-11 |
US20130331461A1 (en) | 2013-12-12 |
PL2678006T3 (pl) | 2016-06-30 |
AU2012219926B2 (en) | 2016-11-17 |
US20130327676A1 (en) | 2013-12-12 |
EP3354259A1 (en) | 2018-08-01 |
CA2827716C (en) | 2019-05-14 |
AU2012219926A1 (en) | 2013-09-12 |
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