PL2623604T3 - Biologiczny system dostarczania i ekspresji oparty na adenowirusie do zastosowania w leczeniu choroby zwyrodnieniowej stawów - Google Patents
Biologiczny system dostarczania i ekspresji oparty na adenowirusie do zastosowania w leczeniu choroby zwyrodnieniowej stawówInfo
- Publication number
- PL2623604T3 PL2623604T3 PL12000703T PL12000703T PL2623604T3 PL 2623604 T3 PL2623604 T3 PL 2623604T3 PL 12000703 T PL12000703 T PL 12000703T PL 12000703 T PL12000703 T PL 12000703T PL 2623604 T3 PL2623604 T3 PL 2623604T3
- Authority
- PL
- Poland
- Prior art keywords
- adenoviral
- osteoarthritis
- treatment
- expression system
- based biological
- Prior art date
Links
- 201000008482 osteoarthritis Diseases 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/54—Interleukins [IL]
- C07K14/545—IL-1
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/10011—Adenoviridae
- C12N2710/10041—Use of virus, viral particle or viral elements as a vector
- C12N2710/10043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/10011—Adenoviridae
- C12N2710/10071—Demonstrated in vivo effect
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/10011—Adenoviridae
- C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
- C12N2710/10341—Use of virus, viral particle or viral elements as a vector
- C12N2710/10343—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/10011—Adenoviridae
- C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
- C12N2710/10371—Demonstrated in vivo effect
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2800/00—Nucleic acids vectors
- C12N2800/24—Vectors characterised by the absence of particular element, e.g. selectable marker, viral origin of replication
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Virology (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Immunology (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Physical Education & Sports Medicine (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP20120000703 EP2623604B8 (en) | 2012-02-02 | 2012-02-02 | Adenoviral-based biological delivery and expression system for use in the treatment of osteoarthritis |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL2623604T3 true PL2623604T3 (pl) | 2015-07-31 |
Family
ID=47891791
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL12000703T PL2623604T3 (pl) | 2012-02-02 | 2012-02-02 | Biologiczny system dostarczania i ekspresji oparty na adenowirusie do zastosowania w leczeniu choroby zwyrodnieniowej stawów |
Country Status (12)
| Country | Link |
|---|---|
| US (4) | US10301647B2 (pl) |
| EP (1) | EP2623604B8 (pl) |
| JP (2) | JP6340320B2 (pl) |
| CN (1) | CN104245941B (pl) |
| AU (1) | AU2013213873B2 (pl) |
| CA (1) | CA2861408C (pl) |
| DK (1) | DK2623604T3 (pl) |
| EA (1) | EA033004B1 (pl) |
| ES (1) | ES2534782T3 (pl) |
| IN (1) | IN2014KN01682A (pl) |
| PL (1) | PL2623604T3 (pl) |
| WO (1) | WO2013114199A1 (pl) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK2948553T3 (da) | 2013-01-25 | 2020-06-29 | Baylor College Medicine | Hjælper-afhængigt afgivelses- og ekspressionssystem til adenoviral genterapi |
| GB201410314D0 (en) * | 2014-06-10 | 2014-07-23 | Advanced Risc Mach Ltd | Display controller |
| RU2017130462A (ru) * | 2015-03-02 | 2019-04-02 | Синлоджик, Инк. | Бактерия, созданная для лечения заболеваний, облегчаемых при уменьшении воспаления кишечника и/или укреплении мукозного барьера кишечника |
| WO2017123934A1 (en) * | 2016-01-13 | 2017-07-20 | Merial, Inc. | Recombinant aav vectors expressing osteoprotective genes, including has2 and lubricin, useful in the treatment of osteoarthritis and related joint conditions in mammals |
| KR20230130155A (ko) * | 2016-08-19 | 2023-09-11 | 유니버시티 오브 플로리다 리서치 파운데이션, 인코포레이티드 | 재조합 자기-상보적인 아데노-부속 바이러스를 이용한 병태의 치료 방법 및 조성물 |
| WO2018071295A1 (en) | 2016-10-10 | 2018-04-19 | The Board Of Trustees Of The Leland Stanford Junior University | Methods and compositions for inducible production of anti-inflammatory cytokines |
| WO2018106956A2 (en) | 2016-12-07 | 2018-06-14 | University Of Florida Research Foundation, Incorporated | IL-1RA CDNAs |
| AU2018254566B2 (en) | 2017-04-21 | 2025-02-13 | Baylor College Of Medicine | Oncolytic virotherapy and immunotherapy |
| CN114616001A (zh) * | 2019-09-18 | 2022-06-10 | 帕西拉制药有限公司 | 用于治疗人骨关节炎的基于腺病毒的生物递送和表达系统的有效剂量以及包含其的组合物 |
| GB2607452B (en) * | 2019-11-14 | 2024-06-05 | Marengo Therapeutics Inc | Anti-TCR antibody molecules and uses thereof |
| CN117280200A (zh) * | 2021-05-06 | 2023-12-22 | 株式会社理学 | X射线造影剂和x射线图像的取得方法 |
| US20230158170A1 (en) * | 2021-08-24 | 2023-05-25 | Pacira Therapeutics, Inc. | IL-1Ra GENE THERAPY FOR INTERVERTEBRAL DISC DEGENERATION |
| WO2024182549A1 (en) | 2023-03-02 | 2024-09-06 | Pacira Therapeutics, Inc. | Compositions and methods for improved adenoviral- based gene therapy utilizing corticosteroid treatment |
| KR20260013513A (ko) * | 2023-04-13 | 2026-01-28 | 메이라지티엑스 진 레귤레이션 리미티드 | 염증 유도성 프로모터 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5747072A (en) | 1993-07-30 | 1998-05-05 | University Of Michigan | Adenoviral-mediated gene transfer to synovial cells in vivo |
| US20030091536A1 (en) | 1999-09-07 | 2003-05-15 | Colorado State University Research Foundation | In vivo treatment of joint disease using interleukin-1 |
| FR2806418B1 (fr) * | 2000-03-14 | 2004-07-16 | Aventis Pharma Sa | Promoteurs hybrides inductibles par l'inflammation, vecteurs les contenant et utilisations |
| WO2002083080A2 (en) | 2001-04-17 | 2002-10-24 | Genetix Pharmaceuticals, Inc. | Method of treating arthritis using lentiviral vectors in gene therapy |
| EP2163562B1 (en) * | 2005-06-21 | 2013-09-18 | XOMA Technology Ltd. | IL-1beta binding antibodies and fragments thereof |
| US8298533B2 (en) * | 2008-11-07 | 2012-10-30 | Medimmune Limited | Antibodies to IL-1R1 |
| US20120045764A1 (en) * | 2009-05-01 | 2012-02-23 | Markus Grompe | Method of expanding human hepatocytes in vivo |
| WO2010138939A1 (en) * | 2009-05-29 | 2010-12-02 | Xoma Technology Ltd. | CARDIOVASCULAR RELATED USES OF IL-1ß ANTIBODIES AND BINDING FRAGMENTS THEREOF |
-
2012
- 2012-02-02 PL PL12000703T patent/PL2623604T3/pl unknown
- 2012-02-02 DK DK12000703.4T patent/DK2623604T3/da active
- 2012-02-02 ES ES12000703.4T patent/ES2534782T3/es active Active
- 2012-02-02 EP EP20120000703 patent/EP2623604B8/en active Active
-
2013
- 2013-01-23 IN IN1682KON2014 patent/IN2014KN01682A/en unknown
- 2013-01-23 AU AU2013213873A patent/AU2013213873B2/en active Active
- 2013-01-23 WO PCT/IB2013/000198 patent/WO2013114199A1/en not_active Ceased
- 2013-01-23 CN CN201380007814.1A patent/CN104245941B/zh active Active
- 2013-01-23 US US14/375,351 patent/US10301647B2/en active Active
- 2013-01-23 JP JP2014555328A patent/JP6340320B2/ja active Active
- 2013-01-23 CA CA2861408A patent/CA2861408C/en active Active
- 2013-01-23 EA EA201491457A patent/EA033004B1/ru unknown
-
2018
- 2018-02-01 JP JP2018016342A patent/JP2018075035A/ja active Pending
-
2019
- 2019-04-30 US US16/398,691 patent/US20190376080A1/en not_active Abandoned
-
2021
- 2021-10-08 US US17/497,045 patent/US20220073948A1/en not_active Abandoned
-
2022
- 2022-06-30 US US17/855,322 patent/US20220348963A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EP2623604A1 (en) | 2013-08-07 |
| CN104245941B (zh) | 2016-12-07 |
| DK2623604T3 (da) | 2015-06-01 |
| EA201491457A1 (ru) | 2014-11-28 |
| CA2861408A1 (en) | 2013-08-08 |
| US10301647B2 (en) | 2019-05-28 |
| EP2623604B1 (en) | 2015-02-25 |
| JP2015506695A (ja) | 2015-03-05 |
| WO2013114199A1 (en) | 2013-08-08 |
| CA2861408C (en) | 2021-10-26 |
| WO2013114199A8 (en) | 2014-09-25 |
| US20150031083A1 (en) | 2015-01-29 |
| IN2014KN01682A (pl) | 2015-10-23 |
| US20190376080A1 (en) | 2019-12-12 |
| JP2018075035A (ja) | 2018-05-17 |
| CN104245941A (zh) | 2014-12-24 |
| AU2013213873B2 (en) | 2018-06-21 |
| EP2623604B8 (en) | 2015-04-22 |
| US20220073948A1 (en) | 2022-03-10 |
| JP6340320B2 (ja) | 2018-06-06 |
| EA033004B1 (ru) | 2019-08-30 |
| AU2013213873A1 (en) | 2014-09-25 |
| US20220348963A1 (en) | 2022-11-03 |
| ES2534782T3 (es) | 2015-04-28 |
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