PL2600865T3 - Związek użyteczny do leczenia chorób, w których pośredniczy mutacja nonsensowna oraz kompozycje farmaceutyczne zawierające wymieniony związek - Google Patents
Związek użyteczny do leczenia chorób, w których pośredniczy mutacja nonsensowna oraz kompozycje farmaceutyczne zawierające wymieniony związekInfo
- Publication number
- PL2600865T3 PL2600865T3 PL11736401T PL11736401T PL2600865T3 PL 2600865 T3 PL2600865 T3 PL 2600865T3 PL 11736401 T PL11736401 T PL 11736401T PL 11736401 T PL11736401 T PL 11736401T PL 2600865 T3 PL2600865 T3 PL 2600865T3
- Authority
- PL
- Poland
- Prior art keywords
- compound
- nonsense
- mutation
- treatment
- pharmaceutical composition
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/436—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/12—Ketones
- A61K31/122—Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4245—Oxadiazoles
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- A—HUMAN NECESSITIES
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
-
- A—HUMAN NECESSITIES
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- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR1056472 | 2010-08-05 | ||
| PCT/EP2011/063126 WO2012016930A1 (en) | 2010-08-05 | 2011-07-29 | Compound useful for the treatment of nonsense-mutation-mediated diseases and pharmaceutical composition comprising said compound |
| EP11736401.8A EP2600865B1 (en) | 2010-08-05 | 2011-07-29 | Compound useful for the treatment of nonsense-mutation-mediated diseases and pharmaceutical composition comprising said compound |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL2600865T3 true PL2600865T3 (pl) | 2019-05-31 |
Family
ID=43447136
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL11736401T PL2600865T3 (pl) | 2010-08-05 | 2011-07-29 | Związek użyteczny do leczenia chorób, w których pośredniczy mutacja nonsensowna oraz kompozycje farmaceutyczne zawierające wymieniony związek |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US9913829B2 (pl) |
| EP (1) | EP2600865B1 (pl) |
| JP (1) | JP5877200B2 (pl) |
| CN (1) | CN103189060A (pl) |
| CA (1) | CA2806825C (pl) |
| DK (1) | DK2600865T3 (pl) |
| ES (1) | ES2710854T3 (pl) |
| IL (1) | IL224544B (pl) |
| PL (1) | PL2600865T3 (pl) |
| WO (1) | WO2012016930A1 (pl) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2659763T3 (es) | 2011-02-14 | 2018-03-19 | The Regents Of The University Of Michigan | Composiciones y procedimientos para el tratamiento de obesidad y trastornos relacionados |
| CN107569487A (zh) | 2012-12-13 | 2018-01-12 | 诺华股份有限公司 | 作为无义突变抑制子的嘧啶并[4,5‑b]喹啉‑4,5(3H,10H)‑二酮 |
| US10987370B2 (en) * | 2012-12-24 | 2021-04-27 | Ramot At Tel-Aviv University Ltd. | Methods of inducing read-through of a nonsense mutation associated with ataxia telangiectasia, Rett syndrome or spinal muscular atrophy by erythromycin or azithromycin |
| WO2014179734A1 (en) | 2013-05-02 | 2014-11-06 | The Regents Of The University Of Michigan | Deuterated amlexanox |
| JP2017507930A (ja) * | 2014-02-07 | 2017-03-23 | ザ リージェンツ オブ ザ ユニヴァシティ オブ ミシガン | ＩＫＫε／ＴＢＫ１阻害剤とベータアドレナリン作動性アゴニストまたは交感神経系活性化剤との組合せ |
| AP2016009545A0 (en) * | 2014-06-03 | 2016-11-30 | Novartis Ag | Naphthyridinedione derivatives |
| ES2743184T3 (es) * | 2014-06-03 | 2020-02-18 | Novartis Ag | Derivados de pirimido[4,5-b]quinolin-4,5(3H,10H)-diona como supresores de mutaciones finalizadoras |
| ES2743183T3 (es) | 2014-06-03 | 2020-02-18 | Novartis Ag | Derivados de piridopirimidinodiona como supresores de mutaciones finalizadoras |
| US20170196842A1 (en) * | 2014-06-06 | 2017-07-13 | Ptc Therapeutics, Inc. | Methods of treatment using a 1,2,4-oxadiazole benzoic acid |
| WO2015198329A1 (en) | 2014-06-25 | 2015-12-30 | Bio Blast Pharma Ltd. | Injectable formulations for intrathecal administration of antibiotic agents |
| WO2016073545A1 (en) | 2014-11-06 | 2016-05-12 | Concert Pharmaceuticals, Inc. | Phenyloxadiazole benzoic acids |
| CN104450727A (zh) * | 2014-11-13 | 2015-03-25 | 深圳华大基因科技有限公司 | X-连锁低磷酸盐血症性佝偻病的致病基因及其编码蛋白质和应用 |
| CA3003132A1 (en) * | 2015-10-30 | 2017-05-04 | Ptc Therapeutics, Inc. | Methods for treating epilepsy |
| WO2017112955A1 (en) | 2015-12-23 | 2017-06-29 | Pharma Llc Moonshot | Methods for inducing an immune response by inhibition of nonsense mediated decay |
| WO2017132538A1 (en) | 2016-01-29 | 2017-08-03 | The Regents Of The University Of Michigan | Amlexanox analogs |
| WO2018050706A1 (en) * | 2016-09-13 | 2018-03-22 | Marco Cipolli | Method of treatment of shwachman-diamond syndrome |
| FR3057776A1 (fr) | 2016-10-21 | 2018-04-27 | Museum National D'histoire Naturelle | Lepista flaccida destine a etre utilise dans le traitement d'une maladie due a une mutation non-sens |
| FR3057774A1 (fr) | 2016-10-21 | 2018-04-27 | Museum National D'histoire Naturelle | Derives de la purine pour leur utilisation dans le traitement ou la prevention de maladies dues a une mutation non-sens |
| US11654135B2 (en) | 2017-06-22 | 2023-05-23 | Moonshot Pharma Llc | Methods for treating colon cancer with compositions comprising amlexanox and immune checkpoint inhibitors |
| CN109200053A (zh) * | 2018-11-17 | 2019-01-15 | 王海玲 | 一种抗癫痫外用药物及其用途 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2770035T3 (es) * | 2003-04-11 | 2020-06-30 | Ptc Therapeutics Inc | Compuesto de ácido 1,2,4-oxadiazol benzoico y su uso para la supresión sin sentido y el tratamiento de enfermedades |
| MX2007012206A (es) * | 2005-04-08 | 2007-12-05 | Ptc Therapeutics Inc | Composiciones de 1,2,4-oxadiazol activo por via oral para terapia de supresion de mutacion interruptora. |
| US7772255B2 (en) | 2005-12-13 | 2010-08-10 | Supratek Pharma, Inc. | Method of treating tumors with azaxanthones |
| WO2008021210A2 (en) | 2006-08-11 | 2008-02-21 | Combinatorx, Incorporated | Methods and compositions for the treatment of neurodegenerative disorders |
| FR2912745A1 (fr) | 2007-02-19 | 2008-08-22 | Centre Nat Rech Scient | Nouveaux composes derives d'indole et compositions pharmaceutiques les contenant |
| AU2008273997A1 (en) * | 2007-07-11 | 2009-01-15 | Cardoz Ab | Combination for use in the treatment of atherosclerosis comprising a mast cell inhibitor and a PPAR gamma agonist |
| WO2009151569A2 (en) | 2008-06-09 | 2009-12-17 | Combinatorx, Incorporated | Beta adrenergic receptor agonists for the treatment of b-cell proliferative disorders |
| WO2010062366A1 (en) * | 2008-10-31 | 2010-06-03 | Arginetix, Inc. | Compositions and methods of treating endothelial disorders |
| WO2010139985A1 (en) | 2009-06-01 | 2010-12-09 | Biocopea Limited | The use of amlexanox in the therapy of neutrophil-driven diseases |
-
2011
- 2011-07-29 ES ES11736401T patent/ES2710854T3/es active Active
- 2011-07-29 PL PL11736401T patent/PL2600865T3/pl unknown
- 2011-07-29 CA CA2806825A patent/CA2806825C/en not_active Expired - Fee Related
- 2011-07-29 WO PCT/EP2011/063126 patent/WO2012016930A1/en active Application Filing
- 2011-07-29 JP JP2013522217A patent/JP5877200B2/ja not_active Expired - Fee Related
- 2011-07-29 DK DK11736401.8T patent/DK2600865T3/en active
- 2011-07-29 EP EP11736401.8A patent/EP2600865B1/en not_active Not-in-force
- 2011-07-29 CN CN2011800479171A patent/CN103189060A/zh active Pending
- 2011-07-29 US US13/813,914 patent/US9913829B2/en active Active
-
2013
- 2013-02-03 IL IL224544A patent/IL224544B/en active IP Right Grant
-
2018
- 2018-01-29 US US15/882,548 patent/US10265302B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP2600865A1 (en) | 2013-06-12 |
| US10265302B2 (en) | 2019-04-23 |
| EP2600865B1 (en) | 2018-11-14 |
| US9913829B2 (en) | 2018-03-13 |
| JP2013535479A (ja) | 2013-09-12 |
| CA2806825A1 (en) | 2012-02-09 |
| US20180147191A1 (en) | 2018-05-31 |
| JP5877200B2 (ja) | 2016-03-02 |
| CN103189060A (zh) | 2013-07-03 |
| DK2600865T3 (en) | 2019-02-25 |
| CA2806825C (en) | 2018-08-21 |
| IL224544B (en) | 2018-07-31 |
| US20130217717A1 (en) | 2013-08-22 |
| ES2710854T3 (es) | 2019-04-29 |
| WO2012016930A1 (en) | 2012-02-09 |
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