PL2590966T3 - Związki chinazolinowe - Google Patents

Związki chinazolinowe

Info

Publication number
PL2590966T3
PL2590966T3 PL11800101T PL11800101T PL2590966T3 PL 2590966 T3 PL2590966 T3 PL 2590966T3 PL 11800101 T PL11800101 T PL 11800101T PL 11800101 T PL11800101 T PL 11800101T PL 2590966 T3 PL2590966 T3 PL 2590966T3
Authority
PL
Poland
Prior art keywords
quinazoline compounds
quinazoline
compounds
Prior art date
Application number
PL11800101T
Other languages
English (en)
Inventor
Weihan Zhang
Wei-Guo Su
Haibin Yang
Yumin Cui
Yongxin Ren
Xiaoqiang Yan
Original Assignee
Hutchison Medipharma Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hutchison Medipharma Limited filed Critical Hutchison Medipharma Limited
Publication of PL2590966T3 publication Critical patent/PL2590966T3/pl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/86—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
    • C07D239/94—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Pulmonology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
PL11800101T 2010-06-30 2011-05-25 Związki chinazolinowe PL2590966T3 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PCT/CN2010/074792 WO2012000182A1 (en) 2010-06-30 2010-06-30 Quinazoline compounds
EP11800101.5A EP2590966B1 (en) 2010-06-30 2011-05-25 Quinazoline compounds

Publications (1)

Publication Number Publication Date
PL2590966T3 true PL2590966T3 (pl) 2017-05-31

Family

ID=45401313

Family Applications (1)

Application Number Title Priority Date Filing Date
PL11800101T PL2590966T3 (pl) 2010-06-30 2011-05-25 Związki chinazolinowe

Country Status (23)

Country Link
US (1) US9168253B2 (pl)
EP (1) EP2590966B1 (pl)
JP (1) JP5736452B2 (pl)
KR (1) KR101480481B1 (pl)
CN (1) CN102906086B (pl)
AU (1) AU2011274183B2 (pl)
BR (1) BR112012033344B1 (pl)
CA (1) CA2801814C (pl)
DK (1) DK2590966T3 (pl)
ES (1) ES2604929T3 (pl)
HR (1) HRP20161490T1 (pl)
HU (1) HUE029801T2 (pl)
LT (1) LT2590966T (pl)
MX (1) MX2012015047A (pl)
MY (1) MY172201A (pl)
PH (1) PH12012502578A1 (pl)
PL (1) PL2590966T3 (pl)
PT (1) PT2590966T (pl)
RS (1) RS55470B1 (pl)
RU (1) RU2530887C2 (pl)
SG (1) SG186410A1 (pl)
SI (1) SI2590966T1 (pl)
WO (2) WO2012000182A1 (pl)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR092289A1 (es) 2011-11-14 2015-04-15 Sunshine Lake Pharma Co Ltd Derivados de aminoquinazolina y sus sales y metodos de uso
CN106117182B (zh) * 2016-06-20 2019-08-30 中国药科大学 喹唑啉-n-苯乙基四氢异喹啉类化合物及其制备方法和应用
CN110023318A (zh) * 2016-12-01 2019-07-16 和记黄埔医药(上海)有限公司 化合物的晶型
CN109694356A (zh) * 2017-10-20 2019-04-30 和记黄埔医药(上海)有限公司 N-(3-炔基苯基)-4,6-二氨基喹唑啉类化合物的合成方法及相关中间体
CN110407837A (zh) * 2018-04-28 2019-11-05 和记黄埔医药(上海)有限公司 化合物的盐、其晶型及其应用
KR101957464B1 (ko) 2018-10-18 2019-03-12 대흥전력기술 주식회사 활선 상태에서 지상기기의 점검 및 누유 보수방법

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3989816A (en) 1975-06-19 1976-11-02 Nelson Research & Development Company Vehicle composition containing 1-substituted azacycloheptan-2-ones
US4444762A (en) 1980-04-04 1984-04-24 Nelson Research & Development Company Vehicle composition containing 1-substituted azacyclopentan-2-ones
GB9718972D0 (en) * 1996-09-25 1997-11-12 Zeneca Ltd Chemical compounds
KR100735639B1 (ko) * 2004-12-29 2007-07-04 한미약품 주식회사 암세포 성장 억제 효과를 갖는 퀴나졸린 유도체 및 이의제조방법
US8426430B2 (en) * 2008-06-30 2013-04-23 Hutchison Medipharma Enterprises Limited Quinazoline derivatives
CN101619043B (zh) * 2008-06-30 2013-06-05 和记黄埔医药(上海)有限公司 喹唑啉衍生物及其医药用途
CN102311438A (zh) * 2010-06-30 2012-01-11 和记黄埔医药(上海)有限公司 喹唑啉化合物

Also Published As

Publication number Publication date
US9168253B2 (en) 2015-10-27
RU2530887C2 (ru) 2014-10-20
KR101480481B1 (ko) 2015-01-09
ES2604929T3 (es) 2017-03-10
DK2590966T3 (en) 2016-12-19
CA2801814C (en) 2015-04-07
JP5736452B2 (ja) 2015-06-17
MX2012015047A (es) 2013-02-07
LT2590966T (lt) 2016-11-25
SI2590966T1 (sl) 2016-12-30
CN102906086A (zh) 2013-01-30
US20130172373A1 (en) 2013-07-04
JP2013529653A (ja) 2013-07-22
MY172201A (en) 2019-11-15
CA2801814A1 (en) 2012-01-05
EP2590966A4 (en) 2014-01-15
HRP20161490T1 (hr) 2016-12-16
BR112012033344B1 (pt) 2020-12-15
BR112012033344A2 (pt) 2016-11-29
PH12012502578A1 (en) 2013-02-11
PT2590966T (pt) 2016-11-29
RU2012153174A (ru) 2014-08-10
HUE029801T2 (en) 2017-04-28
SG186410A1 (en) 2013-01-30
RS55470B1 (sr) 2017-04-28
EP2590966A1 (en) 2013-05-15
WO2012000356A1 (en) 2012-01-05
WO2012000182A1 (en) 2012-01-05
EP2590966B1 (en) 2016-08-31
KR20130031358A (ko) 2013-03-28
AU2011274183B2 (en) 2013-09-26
CN102906086B (zh) 2014-02-12
HK1179954A1 (en) 2013-10-11
AU2011274183A1 (en) 2013-01-10

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