PL2578212T3 - Związek hamujący aktywację enzymu Erk 1/2 do zastosowania w leczeniu chorób neurodegeneracyjnych - Google Patents
Związek hamujący aktywację enzymu Erk 1/2 do zastosowania w leczeniu chorób neurodegeneracyjnychInfo
- Publication number
- PL2578212T3 PL2578212T3 PL10852058T PL10852058T PL2578212T3 PL 2578212 T3 PL2578212 T3 PL 2578212T3 PL 10852058 T PL10852058 T PL 10852058T PL 10852058 T PL10852058 T PL 10852058T PL 2578212 T3 PL2578212 T3 PL 2578212T3
- Authority
- PL
- Poland
- Prior art keywords
- neurogenerative
- erk1
- illnesses
- enzyme
- treatment
- Prior art date
Links
- 101100226056 Dictyostelium discoideum erkA gene Proteins 0.000 title 1
- 102000004190 Enzymes Human genes 0.000 title 1
- 108090000790 Enzymes Proteins 0.000 title 1
- 230000004913 activation Effects 0.000 title 1
- 150000001875 compounds Chemical class 0.000 title 1
- 230000002401 inhibitory effect Effects 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
Landscapes
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Psychology (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP10852058.6A EP2578212B1 (en) | 2010-05-24 | 2010-05-24 | Compound inhibiting activation of the enzyme erk1/2 for use in the treatment of neurogenerative illnesses |
| PCT/ES2010/000228 WO2011147999A1 (es) | 2010-05-24 | 2010-05-24 | Compuesto inhibidor de la activación de la enzima erk1/2 para su uso en el tratamiento de enfermedades neurodegenerativas |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL2578212T3 true PL2578212T3 (pl) | 2017-01-31 |
Family
ID=45003358
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL10852058T PL2578212T3 (pl) | 2010-05-24 | 2010-05-24 | Związek hamujący aktywację enzymu Erk 1/2 do zastosowania w leczeniu chorób neurodegeneracyjnych |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US9000047B2 (pl) |
| EP (1) | EP2578212B1 (pl) |
| PL (1) | PL2578212T3 (pl) |
| WO (1) | WO2011147999A1 (pl) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP4282479A3 (en) | 2015-02-25 | 2024-02-21 | Prilenia Neurotherapeutics Ltd. | Use of pridopidine to treat depression or anxiety |
| CN115697386A (zh) * | 2020-03-24 | 2023-02-03 | 泰伦基国际有限公司 | 一种治疗帕金森病的方法和药物 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4061774A (en) * | 1974-03-02 | 1977-12-06 | Lilly Industries, Limited | Halogenated amino methyl adamantane derivatives |
| ATE94384T1 (de) | 1989-04-14 | 1993-10-15 | Merz & Co Gmbh & Co | Verwendung von adamantan-derivaten zur praevention und behandlung der cerebralen ischaemie. |
| GB9901691D0 (en) * | 1999-01-26 | 1999-03-17 | Cerebrus Ltd | Chemical compounds |
| GB0018272D0 (en) | 2000-07-25 | 2000-09-13 | Vernalis Research Limited | Chemical compounds IV |
| GEP20094759B (en) * | 2002-10-24 | 2009-08-25 | Merz Pharma Gmbh & Co Kgaa | Combination therapy using 1-aminocyclohexane derivatives and acetylcholinesterase inhibitors |
| CN1870984A (zh) | 2003-10-22 | 2006-11-29 | 莫茨药物股份两合公司 | 1-氨基环己烷衍生物用于调节淀粉样病变中原纤维生成Aβ肽的沉积的用途 |
| US8044100B2 (en) | 2004-12-22 | 2011-10-25 | Bellus Health Inc. | Methods and compositions for treating amyloid-related diseases |
| EP1746092A1 (en) | 2005-07-22 | 2007-01-24 | Exonhit Therapeutics SA | Compounds and methods for treatment of amyloid-B-peptide related disorders |
| WO2007017510A2 (de) | 2005-08-11 | 2007-02-15 | Boehringer Ingelheim International Gmbh | Isophthalsäurediamide zur behandlung der alzheimer erkrankung |
| WO2007017507A1 (de) | 2005-08-11 | 2007-02-15 | Boehringer Ingelheim International Gmbh | Inhibitoren der beta-sekretase zur behandlung der alzheimer- erkrankung |
| JP2009504614A (ja) | 2005-08-11 | 2009-02-05 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | アルツハイマー病の治療用化合物 |
| JP2009504612A (ja) | 2005-08-11 | 2009-02-05 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | アルツハイマー病の治療用化合物 |
| ES2341517B1 (es) * | 2008-03-28 | 2011-01-25 | Farmalider, S.A | Utilizacion de un compuesto inhibidor de la activacion de la enzima erk 1/2 en el tratamiento de enfermedades neurodegenerativas. |
-
2010
- 2010-05-24 EP EP10852058.6A patent/EP2578212B1/en not_active Not-in-force
- 2010-05-24 US US13/699,355 patent/US9000047B2/en not_active Expired - Fee Related
- 2010-05-24 WO PCT/ES2010/000228 patent/WO2011147999A1/es not_active Ceased
- 2010-05-24 PL PL10852058T patent/PL2578212T3/pl unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP2578212A1 (en) | 2013-04-10 |
| WO2011147999A1 (es) | 2011-12-01 |
| US20130065966A1 (en) | 2013-03-14 |
| EP2578212B1 (en) | 2016-07-06 |
| US9000047B2 (en) | 2015-04-07 |
| EP2578212A4 (en) | 2013-11-06 |
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