PL2331554T3 - Makrocykliczne pochodne indolu użyteczne jako inhibitory wirusa zapalenia wątroby typu C - Google Patents
Makrocykliczne pochodne indolu użyteczne jako inhibitory wirusa zapalenia wątroby typu CInfo
- Publication number
- PL2331554T3 PL2331554T3 PL09806438T PL09806438T PL2331554T3 PL 2331554 T3 PL2331554 T3 PL 2331554T3 PL 09806438 T PL09806438 T PL 09806438T PL 09806438 T PL09806438 T PL 09806438T PL 2331554 T3 PL2331554 T3 PL 2331554T3
- Authority
- PL
- Poland
- Prior art keywords
- hepatitis
- indole derivatives
- derivatives useful
- virus inhibitors
- macrocyclic indole
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D515/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen, oxygen, and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D515/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen, oxygen, and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D515/08—Bridged systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Virology (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Oncology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP08162435 | 2008-08-14 | ||
| EP09806438A EP2331554B1 (en) | 2008-08-14 | 2009-08-14 | Macrocyclic indole derivatives useful as hepatitis c virus inhibitors |
| PCT/EP2009/060580 WO2010018233A1 (en) | 2008-08-14 | 2009-08-14 | Macrocyclic indole derivatives useful as hepatitis c virus inhibitors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL2331554T3 true PL2331554T3 (pl) | 2013-08-30 |
Family
ID=40276035
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL09806438T PL2331554T3 (pl) | 2008-08-14 | 2009-08-14 | Makrocykliczne pochodne indolu użyteczne jako inhibitory wirusa zapalenia wątroby typu C |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US8357687B2 (pl) |
| EP (1) | EP2331554B1 (pl) |
| CN (1) | CN102124012B (pl) |
| AU (1) | AU2009281138B2 (pl) |
| BR (1) | BRPI0917830A8 (pl) |
| CA (1) | CA2733762C (pl) |
| DK (1) | DK2331554T3 (pl) |
| ES (1) | ES2411916T3 (pl) |
| PL (1) | PL2331554T3 (pl) |
| PT (1) | PT2331554E (pl) |
| RU (1) | RU2518471C2 (pl) |
| WO (1) | WO2010018233A1 (pl) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8524716B2 (en) * | 2007-12-24 | 2013-09-03 | Janssen R&D Ireland | Macrocyclic indoles as hepatitis C virus inhibitors |
| EP2619215B1 (en) | 2010-09-22 | 2018-09-05 | Alios Biopharma, Inc. | Azido nucleosides and nucleotide analogs |
| AU2020394444B2 (en) * | 2019-11-25 | 2025-05-29 | Alkermes, Inc. | Substituted macrocyclic compounds and related methods of treatment |
| US11760747B2 (en) | 2020-12-21 | 2023-09-19 | Alkermes, Inc. | Substituted piperidino compounds and related methods of treatment |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6054472A (en) | 1996-04-23 | 2000-04-25 | Vertex Pharmaceuticals, Incorporated | Inhibitors of IMPDH enzyme |
| US5807876A (en) | 1996-04-23 | 1998-09-15 | Vertex Pharmaceuticals Incorporated | Inhibitors of IMPDH enzyme |
| CZ298463B6 (cs) | 1996-04-23 | 2007-10-10 | Vertex Pharmaceuticals Incorporated | Deriváty mocoviny pro použití jako inhibitory IMPDH enzymu a farmaceutické prostredky, které je obsahují |
| AU6701598A (en) | 1997-03-14 | 1998-09-29 | Vertex Pharmaceuticals Incorporated | Inhibitors of impdh enzyme |
| SK13332001A3 (sk) | 1999-03-19 | 2002-02-05 | Vertex Pharmaceuticals Incorporated | Inhibítory IMPDH enzýmu a ich použitie |
| US6891331B2 (en) | 2000-08-30 | 2005-05-10 | Matsushita Electric Industrial Co., Ltd. | Plasma display unit and production method thereof |
| DE60112611T2 (de) * | 2000-12-08 | 2006-06-14 | Ortho Mcneil Pharm Inc | Makroheterocyclische verbindungen als kinase inhibitoren |
| EP2335700A1 (en) | 2001-07-25 | 2011-06-22 | Boehringer Ingelheim (Canada) Ltd. | Hepatitis C virus polymerase inhibitors with a heterobicylic structure |
| GB0413087D0 (en) | 2004-06-11 | 2004-07-14 | Angeletti P Ist Richerche Bio | Therapeutic compounds |
| WO2006119061A2 (en) * | 2005-05-02 | 2006-11-09 | Merck & Co., Inc. | Hcv ns3 protease inhibitors |
| WO2007092000A1 (en) | 2006-02-06 | 2007-08-16 | Bristol-Myers Squibb Company | Inhibitors of hcv replication |
| US7521443B2 (en) | 2006-05-17 | 2009-04-21 | Bristol-Myers Squibb Company | Cyclopropyl fused indolobenzazepine HCV NS5B inhibitors |
| EP2079479B1 (en) * | 2006-10-24 | 2014-11-26 | Merck Sharp & Dohme Corp. | Hcv ns3 protease inhibitors |
| CA2672250C (en) | 2006-12-20 | 2013-04-30 | Ian Stansfield | Antiviral indoles |
| JP2010533699A (ja) * | 2007-07-17 | 2010-10-28 | イステイチユート・デイ・リチエルケ・デイ・ビオロジア・モレコラーレ・ピ・アンジエレツテイ・エツセ・ピー・アー | Ｃ型肝炎感染症の治療のための大環状インドール誘導体 |
-
2009
- 2009-08-14 PL PL09806438T patent/PL2331554T3/pl unknown
- 2009-08-14 BR BRPI0917830A patent/BRPI0917830A8/pt not_active Application Discontinuation
- 2009-08-14 ES ES09806438T patent/ES2411916T3/es active Active
- 2009-08-14 AU AU2009281138A patent/AU2009281138B2/en not_active Ceased
- 2009-08-14 US US13/058,990 patent/US8357687B2/en not_active Expired - Fee Related
- 2009-08-14 CA CA2733762A patent/CA2733762C/en not_active Expired - Fee Related
- 2009-08-14 PT PT98064389T patent/PT2331554E/pt unknown
- 2009-08-14 RU RU2011109196/04A patent/RU2518471C2/ru not_active IP Right Cessation
- 2009-08-14 EP EP09806438A patent/EP2331554B1/en not_active Not-in-force
- 2009-08-14 DK DK09806438.9T patent/DK2331554T3/da active
- 2009-08-14 WO PCT/EP2009/060580 patent/WO2010018233A1/en not_active Ceased
- 2009-08-14 CN CN200980131582.4A patent/CN102124012B/zh not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| RU2011109196A (ru) | 2012-09-20 |
| ES2411916T3 (es) | 2013-07-09 |
| RU2518471C2 (ru) | 2014-06-10 |
| PT2331554E (pt) | 2013-05-21 |
| BRPI0917830A2 (pt) | 2015-11-24 |
| EP2331554B1 (en) | 2013-03-06 |
| CA2733762C (en) | 2017-01-17 |
| US8357687B2 (en) | 2013-01-22 |
| BRPI0917830A8 (pt) | 2016-07-26 |
| CN102124012B (zh) | 2014-07-02 |
| US20110152279A1 (en) | 2011-06-23 |
| CA2733762A1 (en) | 2010-02-18 |
| AU2009281138A1 (en) | 2010-02-18 |
| EP2331554A1 (en) | 2011-06-15 |
| AU2009281138B2 (en) | 2014-03-27 |
| DK2331554T3 (da) | 2013-05-27 |
| WO2010018233A1 (en) | 2010-02-18 |
| CN102124012A (zh) | 2011-07-13 |
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