PL2326307T3 - Sposób wytwarzania krystalicznych mikrocząstek substancji czynnej - Google Patents

Sposób wytwarzania krystalicznych mikrocząstek substancji czynnej

Info

Publication number
PL2326307T3
PL2326307T3 PL09776893T PL09776893T PL2326307T3 PL 2326307 T3 PL2326307 T3 PL 2326307T3 PL 09776893 T PL09776893 T PL 09776893T PL 09776893 T PL09776893 T PL 09776893T PL 2326307 T3 PL2326307 T3 PL 2326307T3
Authority
PL
Poland
Prior art keywords
active ingredient
producing crystalline
crystalline active
ingredient microparticles
microparticles
Prior art date
Application number
PL09776893T
Other languages
English (en)
Inventor
Detlef Grawe
Sabine Gliesing
Robert Eilers
Original Assignee
Jesalis Pharma Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=41138903&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PL2326307(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Jesalis Pharma Gmbh filed Critical Jesalis Pharma Gmbh
Publication of PL2326307T3 publication Critical patent/PL2326307T3/pl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • H—ELECTRICITY
    • H04—ELECTRIC COMMUNICATION TECHNIQUE
    • H04R—LOUDSPEAKERS, MICROPHONES, GRAMOPHONE PICK-UPS OR LIKE ACOUSTIC ELECTROMECHANICAL TRANSDUCERS; DEAF-AID SETS; PUBLIC ADDRESS SYSTEMS
    • H04R5/00—Stereophonic arrangements

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Physics & Mathematics (AREA)
  • Acoustics & Sound (AREA)
  • Signal Processing (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Steroid Compounds (AREA)
PL09776893T 2008-08-08 2009-06-30 Sposób wytwarzania krystalicznych mikrocząstek substancji czynnej PL2326307T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE102008037025.8A DE102008037025C5 (de) 2008-08-08 2008-08-08 Verfahren zur Herstellung kristalliner Wirkstoff-Mikropartikel bzw. einer Wirkstoffpartikel-Festkörperform
PCT/EP2009/004724 WO2010015298A2 (de) 2008-08-08 2009-06-30 Kristalline wirkstoff-mikropartikel, verfahren zu deren herstellung und verwendung in arzneimitteln
EP09776893.1A EP2326307B1 (de) 2008-08-08 2009-06-30 Verfahren zur herstellung kristalliner wirkstoff-mikropartikel

Publications (1)

Publication Number Publication Date
PL2326307T3 true PL2326307T3 (pl) 2016-04-29

Family

ID=41138903

Family Applications (1)

Application Number Title Priority Date Filing Date
PL09776893T PL2326307T3 (pl) 2008-08-08 2009-06-30 Sposób wytwarzania krystalicznych mikrocząstek substancji czynnej

Country Status (14)

Country Link
US (1) US9173843B2 (pl)
EP (2) EP2944307A1 (pl)
CN (1) CN102112113B (pl)
AU (1) AU2009278348B2 (pl)
CA (1) CA2732952C (pl)
CH (1) CH701977B1 (pl)
DE (1) DE102008037025C5 (pl)
DK (1) DK2326307T3 (pl)
ES (1) ES2557904T3 (pl)
HU (1) HUE027232T2 (pl)
PL (1) PL2326307T3 (pl)
PT (1) PT2326307E (pl)
RU (1) RU2011108220A (pl)
WO (1) WO2010015298A2 (pl)

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DE102009056916B4 (de) 2009-12-03 2011-07-21 Siemens Medical Instruments Pte. Ltd. Hörgerät mit einer platzsparenden Anordnung von Mikrofonen und Schallöffnungen
DE102010003711B4 (de) * 2010-04-08 2015-04-09 Jesalis Pharma Gmbh Verfahren zur Herstellung kristalliner Wirkstoffpartikel
US11351122B1 (en) 2010-07-28 2022-06-07 Laboratorios Leon Farma Sa Synthetic progestogens and pharmaceutical compositions comprising the same
US10849857B2 (en) 2010-07-28 2020-12-01 Laboratorios Leon Farma Sa Pharmaceutical compositions comprising active drugs, contraceptive kits comprising active drugs, and methods of administering the same
AR081670A1 (es) 2010-06-29 2012-10-10 Leon Farma Sa Lab Composicion farmaceutica que comprende drospirenona y kit anticonceptivo
DE102011051635B4 (de) 2011-07-07 2015-02-19 Borgwarner Ludwigsburg Gmbh Verfahren zum Steuern einer Korona Zündeinrichtung
JO3387B1 (ar) 2011-12-16 2019-03-13 Glaxosmithkline Llc مشتقات بيتولين
US8765725B2 (en) 2012-05-08 2014-07-01 Aciex Therapeutics, Inc. Preparations of hydrophobic therapeutic agents, methods of manufacture and use thereof
EP2847207B1 (en) 2012-05-08 2019-03-27 Nicox Ophthalmics, Inc. Fluticasone propionate nanocrystals
DE102012221219B4 (de) 2012-11-20 2014-05-28 Jesalis Pharma Gmbh Verfahren zur Vergrößerung der Partikelgröße kristalliner Wirkstoff-Mikropartikel
WO2014093941A1 (en) * 2012-12-14 2014-06-19 Glaxosmithkline Llc Pharmaceutical compositions
US9815865B2 (en) 2013-01-07 2017-11-14 Nicox Ophthalmics, Inc. Preparations of hydrophobic therapeutic agents, methods of manufacture and use thereof
DE102013108705B4 (de) * 2013-08-12 2017-04-27 Borgwarner Ludwigsburg Gmbh Koronazündsystem und Verfahren zum Steuern einer Koronazündeinrichtung
KR20170056702A (ko) 2014-09-26 2017-05-23 글락소스미스클라인 인털렉츄얼 프로퍼티 (넘버 2) 리미티드 지효성 약제학적 조성물
CN108490793B (zh) * 2018-05-21 2021-07-27 山东大学 一种结晶过程粒度分布建模与控制方法
CN110655551A (zh) * 2019-09-23 2020-01-07 华润紫竹药业有限公司 一种地诺孕素药物单一新晶型及其制备方法
IT202100008834A1 (it) * 2021-04-08 2022-10-08 Ind Chimica Srl Processo per la preparazione di drospirenone come polvere fine tramite duplice cambio di forma cristallina
GB2620876A (en) * 2021-04-08 2024-01-24 Ind Chimica Srl Process for the preparation of drospirenone as a fine powder through a double change of crystalline form

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FR2602423B1 (fr) * 1986-08-08 1989-05-05 Ethypharm Sa Procede de preparation d'un medicament a base de fenofibrate, medicament obtenu par ce procede
NL194638C (nl) 1986-12-19 2002-10-04 Novartis Ag Hydrosol die vaste deeltjes van een farmaceutisch actieve stof bevat en farmaceutisch preparaat dat deze hydrosol bevat.
JP2642486B2 (ja) * 1989-08-04 1997-08-20 田辺製薬株式会社 難溶性薬物の超微粒子化法
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US5091187A (en) 1990-04-26 1992-02-25 Haynes Duncan H Phospholipid-coated microcrystals: injectable formulations of water-insoluble drugs
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DK19393D0 (da) * 1993-02-19 1993-02-19 Danochemo As Fremgangsmaade til fremstilling af et i vand dispergerbart pulverformigt carotenoidpraeparat
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US5622938A (en) * 1995-02-09 1997-04-22 Nano Systems L.L.C. Sugar base surfactant for nanocrystals
DE19652196A1 (de) 1996-12-16 1998-06-18 Jenapharm Gmbh Homogene steroidhaltige Präformulierungen zur Herstellung niedrigdosierter fester und halbfester pharmazeutischer Zubereitungen
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JP4354667B2 (ja) 1999-08-31 2009-10-28 バイエル・シエーリング・ファーマ・アクチエンゲゼルシャフト 避妊薬としての使用へのエチニルエストラジオールとドロスピレノンの医薬用組合せ
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DE10218107A1 (de) * 2002-04-23 2003-11-20 Jenapharm Gmbh Verfahren zum Herstellen von Kristallen von Steroiden, danach erhältliche Kristalle und deren Verwendung in pharmazeutischen Formulierungen
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EP1625849A1 (en) * 2004-08-09 2006-02-15 Liconsa, Liberacion Controlada de Sustancias Activas, S.A. Pharmaceutical composition comprising drospirenone and ethynylestradiol
US7388096B2 (en) * 2004-09-28 2008-06-17 Bristol-Myers Squibb Company Crystalline forms of a factor Xa inhibitor
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JP5197564B2 (ja) * 2006-03-14 2013-05-15 メルク・シャープ・エンド・ドーム・コーポレイション 微細粉砕及び微細な種での結晶化により有機結晶微細粒子組成物を製造する方法
EP1944018A1 (en) * 2007-01-10 2008-07-16 CHIESI FARMACEUTICI S.p.A. Micronised particles of low-dosage strength active agents for powder formulations for inhalation

Also Published As

Publication number Publication date
CH701977B1 (de) 2013-07-15
AU2009278348A1 (en) 2010-02-11
US9173843B2 (en) 2015-11-03
DE102008037025C5 (de) 2016-07-07
CN102112113A (zh) 2011-06-29
ES2557904T3 (es) 2016-01-29
RU2011108220A (ru) 2012-09-20
CN102112113B (zh) 2014-06-25
PT2326307E (pt) 2016-02-02
EP2326307A2 (de) 2011-06-01
EP2944307A1 (de) 2015-11-18
DE102008037025A1 (de) 2010-02-11
WO2010015298A2 (de) 2010-02-11
WO2010015298A3 (de) 2011-03-10
AU2009278348B2 (en) 2014-07-31
CA2732952C (en) 2016-08-23
US20110144071A1 (en) 2011-06-16
DE102008037025B4 (de) 2011-09-22
EP2326307B1 (de) 2015-10-28
DK2326307T3 (en) 2016-01-25
HUE027232T2 (en) 2016-08-29
CA2732952A1 (en) 2010-02-11

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