PL222088A1 - - Google Patents

Info

Publication number
PL222088A1
PL222088A1 PL22208880A PL22208880A PL222088A1 PL 222088 A1 PL222088 A1 PL 222088A1 PL 22208880 A PL22208880 A PL 22208880A PL 22208880 A PL22208880 A PL 22208880A PL 222088 A1 PL222088 A1 PL 222088A1
Authority
PL
Poland
Application number
PL22208880A
Other versions
PL129707B1 (en
Original Assignee
Boehringer Mannheim Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Mannheim Gmbh filed Critical Boehringer Mannheim Gmbh
Publication of PL222088A1 publication Critical patent/PL222088A1/xx
Publication of PL129707B1 publication Critical patent/PL129707B1/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D203/00Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D203/04Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D203/06Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D203/22Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to the ring nitrogen atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Transplantation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
PL1980222088A 1979-02-21 1980-02-18 Process for preparing novel n-substituted derivatives of aziridine-2-carboxylic acid PL129707B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19792906603 DE2906603A1 (de) 1979-02-21 1979-02-21 N-substituierte aziridin-2-carbonsaeurederivate, verfahren zu deren herstellung sowie diese substanzen enthaltende arzneimittel

Publications (2)

Publication Number Publication Date
PL222088A1 true PL222088A1 (en, 2012) 1980-12-01
PL129707B1 PL129707B1 (en) 1984-06-30

Family

ID=6063481

Family Applications (1)

Application Number Title Priority Date Filing Date
PL1980222088A PL129707B1 (en) 1979-02-21 1980-02-18 Process for preparing novel n-substituted derivatives of aziridine-2-carboxylic acid

Country Status (19)

Country Link
US (2) US4397848A (en, 2012)
EP (1) EP0014976B1 (en, 2012)
JP (1) JPS55113760A (en, 2012)
AR (1) AR223863A1 (en, 2012)
AT (1) ATE818T1 (en, 2012)
AU (1) AU529982B2 (en, 2012)
CA (1) CA1148962A (en, 2012)
CS (1) CS208798B2 (en, 2012)
DD (1) DD148772A5 (en, 2012)
DE (2) DE2906603A1 (en, 2012)
ES (1) ES488656A1 (en, 2012)
FI (1) FI70702C (en, 2012)
HU (1) HU182801B (en, 2012)
IE (1) IE49267B1 (en, 2012)
IL (1) IL59425A (en, 2012)
PL (1) PL129707B1 (en, 2012)
PT (1) PT70847A (en, 2012)
SU (1) SU1181541A3 (en, 2012)
ZA (1) ZA80902B (en, 2012)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4925835A (en) * 1986-05-01 1990-05-15 Sloan-Kettering Institute For Cancer Research Aziridinyl putrescine containing compositions and their uses in treating prostate cancer
JPH07301287A (ja) * 1995-03-23 1995-11-14 Sumitomo Heavy Ind Ltd 制御装置に用いられる内接噛合遊星歯車機構
DE69819192T2 (de) 1997-06-27 2004-06-09 Amplimed, Inc., Tucson Neue cyanoaziridine zur behandlung von krebs
WO2002041871A2 (en) * 2000-11-21 2002-05-30 Board Of Regents, The University Of Texas System Composition comprising an imexon or derivatives thereof and lipids
US20030129222A1 (en) * 2000-11-21 2003-07-10 Gabriel Lopez-Berestein Liposomal imexon
US7011846B2 (en) * 2001-12-21 2006-03-14 Shire Laboratories, Inc. Oral capsule formulation with increased physical stability
US20040005339A1 (en) * 2002-06-28 2004-01-08 Shojaei Amir H. Formulations of fenofibrate and/or fenofibrate derivatives with improved oral bioavailability
DK1599468T3 (da) 2003-01-14 2008-02-04 Arena Pharm Inc 1,2,3-trisubstituerede aryl- og heteroarylderivater som modulatorer af metabolisme og forebyggelse og behandling af forstyrrelser forbundet dermed såsom diabetes og hyperglykæmi
DE602004017703D1 (de) * 2003-02-24 2008-12-24 Arena Pharm Inc Phenyl- und pyridylpiperidinderivate als modulatoren des glucose-metabolismus
AR045047A1 (es) 2003-07-11 2005-10-12 Arena Pharm Inc Derivados arilo y heteroarilo trisustituidos como moduladores del metabolismo y de la profilaxis y tratamiento de desordenes relacionados con los mismos
CN101870690A (zh) * 2004-06-04 2010-10-27 艾尼纳制药公司 作为代谢调节剂的经取代芳基和杂芳基衍生物及其相关病症的预防和治疗
MY148521A (en) 2005-01-10 2013-04-30 Arena Pharm Inc Substituted pyridinyl and pyrimidinyl derivatives as modulators of metabolism and the treatment of disorders related thereto
DOP2006000010A (es) 2005-01-10 2006-07-31 Arena Pharm Inc Procedimiento para preparar eteres aromáticos
CA2619093A1 (en) * 2005-09-16 2007-03-29 Arena Pharmaceuticals, Inc. Modulators of metabolism and the treatment of disorders related thereto
TW200811147A (en) * 2006-07-06 2008-03-01 Arena Pharm Inc Modulators of metabolism and the treatment of disorders related thereto
TW200811140A (en) * 2006-07-06 2008-03-01 Arena Pharm Inc Modulators of metabolism and the treatment of disorders related thereto
SG182610A1 (en) 2010-01-27 2012-08-30 Arena Pharm Inc Processes for the preparation of (r)-2-(7-(4-cyclopentyl-3-(trifluoromethyl)benzyloxy)-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl)acetic acid and salts thereof
JP5941916B2 (ja) 2010-09-22 2016-06-29 アリーナ ファーマシューティカルズ, インコーポレイテッド Gpr119レセプターのモジュレーターおよびそれに関連する障害の処置
ES2995737T3 (en) 2015-01-06 2025-02-11 Arena Pharm Inc Compound for use in treating conditions related to the s1p1 receptor
US10301262B2 (en) 2015-06-22 2019-05-28 Arena Pharmaceuticals, Inc. Crystalline L-arginine salt of (R)-2-(7-(4-cyclopentyl-3-(trifluoromethyl)benzyloxy)-1,2,3,4-tetrahydrocyclo-penta [b]indol-3-yl)acetic acid(Compund1) for use in SIPI receptor-associated disorders
AU2018220521A1 (en) 2017-02-16 2019-09-05 Arena Pharmaceuticals, Inc. Compounds and methods for treatment of primary biliary cholangitis
ES2987794T3 (es) 2018-06-06 2024-11-18 Arena Pharm Inc Procedimientos de tratamiento de afecciones relacionadas con el receptor S1P1
CN113816887A (zh) * 2021-08-31 2021-12-21 华中科技大学 一种氮杂环丙烷类化合物及其制备方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2644820A1 (de) * 1976-10-05 1978-04-06 Boehringer Mannheim Gmbh Cancerostatisch und immunstimulierend wirkende 1-(n-acyl-carbamoyl)-2-cyanaziridine sowie verfahren zur herstellung derselben
DE2731264A1 (de) 1977-07-11 1979-02-01 Boehringer Mannheim Gmbh Neue 1-acyl-2-cyanaziridine, verfahren zu deren herstellung und diese verbindungen enthaltende pharmazeutische zubereitungen

Also Published As

Publication number Publication date
ES488656A1 (es) 1980-09-16
PT70847A (de) 1980-03-01
FI70702C (fi) 1986-10-06
DD148772A5 (de) 1981-06-10
US4517183A (en) 1985-05-14
PL129707B1 (en) 1984-06-30
IL59425A0 (en) 1980-05-30
DE3060268D1 (en) 1982-05-19
JPS55113760A (en) 1980-09-02
AU529982B2 (en) 1983-06-30
US4397848A (en) 1983-08-09
AU5564980A (en) 1980-08-28
JPH0150700B2 (en, 2012) 1989-10-31
FI70702B (fi) 1986-06-26
DE2906603A1 (de) 1980-09-04
AR223863A1 (es) 1981-09-30
IL59425A (en) 1984-05-31
CA1148962A (en) 1983-06-28
ATE818T1 (de) 1982-04-15
EP0014976B1 (de) 1982-04-07
IE49267B1 (en) 1985-09-04
ZA80902B (en) 1981-03-25
HU182801B (en) 1984-03-28
CS208798B2 (en) 1981-09-15
SU1181541A3 (ru) 1985-09-23
IE800327L (en) 1980-08-21
EP0014976A1 (de) 1980-09-03
FI800510A7 (fi) 1980-08-22

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