PL1910538T3 - Sposób syntezy kodowanych bibliotek - Google Patents

Sposób syntezy kodowanych bibliotek

Info

Publication number
PL1910538T3
PL1910538T3 PL06784718T PL06784718T PL1910538T3 PL 1910538 T3 PL1910538 T3 PL 1910538T3 PL 06784718 T PL06784718 T PL 06784718T PL 06784718 T PL06784718 T PL 06784718T PL 1910538 T3 PL1910538 T3 PL 1910538T3
Authority
PL
Poland
Prior art keywords
synthesis
methods
encoded libraries
libraries
encoded
Prior art date
Application number
PL06784718T
Other languages
English (en)
Inventor
Barry Morgan
Stephen Hale
Christopher C Arico-Muendel
Matthew Clark
Richard Wagner
Malcolm J Kavarana
Steffen Phillip Creaser
George J Franklin
Paolo A Centrella
David I Israel
Malcolm L Gefter
Dennis Benjamin
Nils Jakob Vest Hansen
Raksha A Acharya
Original Assignee
Praecis Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=36930432&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PL1910538(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Praecis Pharm Inc filed Critical Praecis Pharm Inc
Publication of PL1910538T3 publication Critical patent/PL1910538T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B61/00—Other general methods
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1068—Template (nucleic acid) mediated chemical library synthesis, e.g. chemical and enzymatical DNA-templated organic molecule synthesis, libraries prepared by non ribosomal polypeptide synthesis [NRPS], DNA/RNA-polymerase mediated polypeptide synthesis

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Steroid Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Saccharide Compounds (AREA)
  • Polyurethanes Or Polyureas (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Compounds Of Unknown Constitution (AREA)
PL06784718T 2005-06-09 2006-06-09 Sposób syntezy kodowanych bibliotek PL1910538T3 (pl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US68946605P 2005-06-09 2005-06-09
US73104105P 2005-10-28 2005-10-28
PCT/US2006/022555 WO2006135786A2 (en) 2005-06-09 2006-06-09 Methods for synthesis of encoded libraries
EP06784718A EP1910538B1 (en) 2005-06-09 2006-06-09 Methods for synthesis of encoded libraries

Publications (1)

Publication Number Publication Date
PL1910538T3 true PL1910538T3 (pl) 2011-12-30

Family

ID=36930432

Family Applications (2)

Application Number Title Priority Date Filing Date
PL06784718T PL1910538T3 (pl) 2005-06-09 2006-06-09 Sposób syntezy kodowanych bibliotek
PL10075295T PL2258870T3 (pl) 2005-06-09 2006-06-09 Sposób identyfikacji związków, które wiążą się z docelową cząsteczką biologiczną

Family Applications After (1)

Application Number Title Priority Date Filing Date
PL10075295T PL2258870T3 (pl) 2005-06-09 2006-06-09 Sposób identyfikacji związków, które wiążą się z docelową cząsteczką biologiczną

Country Status (24)

Country Link
EP (4) EP2311786A3 (pl)
JP (2) JP5508711B2 (pl)
KR (1) KR101346432B1 (pl)
CN (2) CN102392014A (pl)
AT (1) ATE507292T1 (pl)
AU (1) AU2006257915B2 (pl)
BR (1) BRPI0613566B1 (pl)
CA (1) CA2611512C (pl)
CY (1) CY1112036T1 (pl)
DE (1) DE602006021580D1 (pl)
DK (4) DK2258870T3 (pl)
ES (2) ES2365534T3 (pl)
HK (2) HK1120546A1 (pl)
HR (1) HRP20110528T1 (pl)
IL (1) IL187977A (pl)
NO (1) NO343698B1 (pl)
NZ (1) NZ564545A (pl)
PL (2) PL1910538T3 (pl)
PT (2) PT1910538E (pl)
RS (1) RS51868B (pl)
RU (2) RU2459869C2 (pl)
SI (1) SI1910538T1 (pl)
WO (1) WO2006135786A2 (pl)
ZA (2) ZA200800190B (pl)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1401850A1 (en) 2001-06-20 2004-03-31 Nuevolution A/S Nucleoside derivatives for library preparation
IL163822A0 (en) 2002-03-15 2005-12-18 Nuevolution As An improved method for synthesising templated molecules
WO2004013070A2 (en) 2002-08-01 2004-02-12 Nuevolution A/S Multi-step synthesis of templated molecules
WO2004039825A2 (en) 2002-10-30 2004-05-13 Nuevolution A/S Method for the synthesis of a bifunctional complex
AU2003291964A1 (en) 2002-12-19 2004-07-14 Nuevolution A/S Quasirandom structure and function guided synthesis methods
WO2004074429A2 (en) 2003-02-21 2004-09-02 Nuevolution A/S Method for producing second-generation library
EP1670939B1 (en) 2003-09-18 2009-11-04 Nuevolution A/S A method for obtaining structural information concerning an encoded molecule and method for selecting compounds
PT1910538E (pt) 2005-06-09 2011-07-28 Praecis Pharm Inc Métodos para a síntese de bibliotecas codificadas
LT2336315T (lt) 2005-12-01 2017-11-10 Nuevolution A/S Fermentiniai kodavimo būdai, skirti efektyviai didelių bibliotekų sintezei
WO2010094036A1 (en) 2009-02-13 2010-08-19 X-Chem, Inc. Methods of creating and screening dna-encoded libraries
SI2558577T1 (sl) 2010-04-16 2019-05-31 Nuevolution A/S Bifunkcionalni kompleksi in metode za pripravo in uporabo takšnih kompleksov
DK2748357T3 (en) * 2011-09-07 2018-07-16 X Chem Inc Methods for labeling DNA-encoded libraries
CA2879018A1 (en) 2012-07-13 2014-01-16 X-Chem, Inc. Dna-encoded libraries having encoding oligonucleotide linkages not readable by polymerases
US20200149034A1 (en) * 2017-03-17 2020-05-14 Hitgen Ltd. Methods and Compositions for Synthesis of Encoded Libraries
WO2019149198A1 (zh) * 2018-01-31 2019-08-08 成都先导药物开发股份有限公司 一种dna编码化合物库及化合物筛选方法
GB201821109D0 (en) * 2018-12-21 2019-02-06 Philochem Ag Nucleic acid encoded chemical libraries
CN110041390B (zh) * 2019-04-26 2022-05-27 上海药明康德新药开发有限公司 DNA编码化合物库中On-DNA的1,2,3-三氮唑化合物的合成方法
CN112779606A (zh) * 2019-11-06 2021-05-11 成都先导药物开发股份有限公司 一种On-DNA曼尼希反应的方法
CN113089104B (zh) * 2019-12-23 2023-03-28 成都先导药物开发股份有限公司 一种On-DNA二胺化合物关环反应的合成方法
EP4201951B1 (en) * 2021-12-21 2023-11-22 Bachem Holding AG Method for peptide synthesis
CN114920791B (zh) * 2022-04-28 2024-06-18 康龙化成(宁波)科技发展有限公司 一种寡聚核酸-琥珀酰亚胺化合物的合成方法

Family Cites Families (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1545804A (en) 1924-12-26 1925-07-14 Warmerdam Nicholas Sash fastener
US4356270A (en) 1977-11-08 1982-10-26 Genentech, Inc. Recombinant DNA cloning vehicle
US4293652A (en) 1979-05-25 1981-10-06 Cetus Corporation Method for synthesizing DNA sequentially
US4458066A (en) 1980-02-29 1984-07-03 University Patents, Inc. Process for preparing polynucleotides
US4416988A (en) 1980-12-23 1983-11-22 Harvey Rubin Detection and isolation of enkephalin mRNA using a synthetic oligodeoxynucleotide
JPS60222842A (ja) 1984-04-19 1985-11-07 Fuji Photo Film Co Ltd ハロゲン化銀写真乳剤およびその製造方法
US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
US4965188A (en) 1986-08-22 1990-10-23 Cetus Corporation Process for amplifying, detecting, and/or cloning nucleic acid sequences using a thermostable enzyme
US4800159A (en) 1986-02-07 1989-01-24 Cetus Corporation Process for amplifying, detecting, and/or cloning nucleic acid sequences
US5360928A (en) 1989-10-23 1994-11-01 Research Corporation Technologies, Inc. Synthesis and use of amino acid fluorides as peptide coupling reagents
CA2118806A1 (en) 1991-09-18 1993-04-01 William J. Dower Method of synthesizing diverse collections of oligomers
US5573905A (en) * 1992-03-30 1996-11-12 The Scripps Research Institute Encoded combinatorial chemical libraries
US5565324A (en) * 1992-10-01 1996-10-15 The Trustees Of Columbia University In The City Of New York Complex combinatorial chemical libraries encoded with tags
EP0675873A4 (en) 1992-12-11 2000-03-29 Chiron Corp PRODUCTION OF CODED POLYMERS
US6537776B1 (en) * 1999-06-14 2003-03-25 Diversa Corporation Synthetic ligation reassembly in directed evolution
US7479472B1 (en) 1998-10-19 2009-01-20 The Board Of Trustees Of The Leland Stanford Junior University DNA-templated combinatorial library chemistry
US7070928B2 (en) 2001-03-19 2006-07-04 President And Fellows Of Harvard College Evolving new molecular function
EP1905829B1 (en) 2001-06-20 2016-02-17 Nuevolution A/S Templated molecules and methods for using such molecules
ES2346646T5 (es) 2002-05-30 2018-02-15 The Scripps Research Institute Ligación catalizada con cobre de azidas y acetilenos
CA2495881C (en) * 2002-08-19 2014-07-08 The President And Fellows Of Harvard College Evolving new molecular function
WO2004039825A2 (en) * 2002-10-30 2004-05-13 Nuevolution A/S Method for the synthesis of a bifunctional complex
EP2159285B1 (en) 2003-01-29 2012-09-26 454 Life Sciences Corporation Methods of amplifying and sequencing nucleic acids
GB0304433D0 (en) * 2003-02-27 2003-04-02 Xceleron Ltd Improvements relating to chemical libraries
ATE424455T1 (de) * 2003-03-20 2009-03-15 Nuevolution As Ligationsvermittelnde codierung von kleinen molekülen
EP1670939B1 (en) * 2003-09-18 2009-11-04 Nuevolution A/S A method for obtaining structural information concerning an encoded molecule and method for selecting compounds
RU2470077C2 (ru) * 2003-12-17 2012-12-20 ГЛЭКСОСМИТКЛАЙН ЭлЭлСи Биологически активное соединение, содержащее кодирующий олигонуклеотид (варианты), способ его синтеза, библиотека соединений (варианты), способ ее синтеза и способ поиска соединения, связывающегося с биологической мишенью (варианты)
US7116036B2 (en) 2004-08-02 2006-10-03 General Electric Company Energy harvesting system, apparatus and method
WO2006053571A2 (en) * 2004-11-22 2006-05-26 Peter Birk Rasmussen Template directed split and mix systhesis of small molecule libraries
PT1910538E (pt) 2005-06-09 2011-07-28 Praecis Pharm Inc Métodos para a síntese de bibliotecas codificadas

Also Published As

Publication number Publication date
DE602006021580D1 (de) 2011-06-09
CA2611512A1 (en) 2006-12-21
SI1910538T1 (sl) 2011-09-30
ES2401485T3 (es) 2013-04-22
HK1120546A1 (en) 2009-04-03
KR20080036577A (ko) 2008-04-28
IL187977A0 (en) 2008-03-20
EP1910538A2 (en) 2008-04-16
JP5508711B2 (ja) 2014-06-04
NO343698B1 (no) 2019-05-13
ES2365534T3 (es) 2011-10-06
CN101233235B (zh) 2012-10-03
IL187977A (en) 2013-02-28
RU2008100035A (ru) 2009-07-20
CY1112036T1 (el) 2015-11-04
BRPI0613566A2 (pt) 2011-01-18
EP2311786A3 (en) 2014-04-02
ZA200800190B (en) 2010-11-24
JP2008543289A (ja) 2008-12-04
ATE507292T1 (de) 2011-05-15
DK177345B1 (da) 2013-01-28
AU2006257915A1 (en) 2006-12-21
CN101233235A (zh) 2008-07-30
WO2006135786A2 (en) 2006-12-21
PL2258870T3 (pl) 2013-05-31
ZA201004791B (en) 2012-06-27
NZ564545A (en) 2011-03-31
EP2338990A3 (en) 2011-10-19
DK2258870T3 (da) 2013-03-18
DK200800005A (da) 2008-03-04
NO20076362L (no) 2008-03-07
PT1910538E (pt) 2011-07-28
AU2006257915B2 (en) 2011-09-08
CA2611512C (en) 2018-05-22
RU2459869C2 (ru) 2012-08-27
EP2258870A2 (en) 2010-12-08
DK179064B1 (da) 2017-10-02
CN102392014A (zh) 2012-03-28
EP2258870B1 (en) 2013-01-02
RU2011101778A (ru) 2012-07-27
JP2014039550A (ja) 2014-03-06
DK1910538T3 (da) 2011-08-08
BRPI0613566B1 (pt) 2020-01-07
PT2258870E (pt) 2013-04-01
EP2311786A2 (en) 2011-04-20
HK1150454A1 (en) 2011-12-30
EP2258870A3 (en) 2011-11-30
EP1910538B1 (en) 2011-04-27
HRP20110528T1 (hr) 2011-09-30
WO2006135786A3 (en) 2007-06-21
EP2338990A2 (en) 2011-06-29
DK201170734A (en) 2011-12-20
KR101346432B1 (ko) 2014-02-14
RS51868B (en) 2012-02-29

Similar Documents

Publication Publication Date Title
DK201170734A (en) Methods for synthesis of encoded libraries
WO2005058479A3 (en) Methods for synthesis of encoded libraries
WO2007053358A3 (en) Methods for identifying compounds of interest using encoded libraries
HK1213815A1 (zh) 合成種 抑制劑的方法
WO2008033848A3 (en) Self-assembled combinatorial encoding nanoarrays for multiplexed biosensing
SI2292607T1 (sl) Postopek za sintezo organskih spojin
SI1509517T1 (sl) Nova sinteza irbesartana
EP1649080A4 (en) APPARATUS FOR PRODUCING OZONE BY ELECTROLYSIS
IL176321A (en) Process for eco-friendly synthesis of bromobenzene
ZA200805207B (en) Process for producing condensed-phase product from one or more gas-phase reactants
ATE423764T1 (de) Verfahren zur herstellung von hydrazon-derivaten
ZA200707267B (en) Process for enantioselective synthesis of single enantiomers of thio-substituted arylmethanesulfinyl derivatives by asymmetric oxidation field of the invention
TW200621698A (en) Synthesis of idarubicin aglycone
WO2004031745A3 (de) Qualitätskontrolle von mikroarray sensorfeldern
ZA200600529B (en) Methods for synthesis of encoded libraries
CY1114172T1 (el) Μεθοδοι για ταυτοποιηση ενωσεων οι οποιες δεσμευονται σε βιολογικο μοριο στοχο
PT2341140T (pt) Métodos de codificação enzimática para síntese eficaz de bibliotecas grandes
TH112999B (th) วิธีการสำหรับผลิตเครื่องดนตรีประเภทตีหรือเคาะ
PL373880A1 (pl) Preparat wodo- i chemoodporny
GB0503343D0 (en) Methods of chemical synthesis