PL1901736T3 - Kompozycja farmaceutyczna zawierająca symwastatynę i ezetymib - Google Patents
Kompozycja farmaceutyczna zawierająca symwastatynę i ezetymibInfo
- Publication number
- PL1901736T3 PL1901736T3 PL06762303T PL06762303T PL1901736T3 PL 1901736 T3 PL1901736 T3 PL 1901736T3 PL 06762303 T PL06762303 T PL 06762303T PL 06762303 T PL06762303 T PL 06762303T PL 1901736 T3 PL1901736 T3 PL 1901736T3
- Authority
- PL
- Poland
- Prior art keywords
- ezetimibe
- simvastatin
- pharmaceutical composition
- oxygen
- present
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/397—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having four-membered rings, e.g. azetidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
- A61K31/366—Lactones having six-membered rings, e.g. delta-lactones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
- A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP05014680A EP1741427A1 (en) | 2005-07-06 | 2005-07-06 | Pharmaceutical composition comprising simvastatin and ezetimibe |
EP06762303A EP1901736B1 (en) | 2005-07-06 | 2006-06-30 | Pharmaceutical composition comprising simvastatin and ezetimibe |
PCT/EP2006/006369 WO2007003365A1 (en) | 2005-07-06 | 2006-06-30 | Pharmaceutical composition comprising simvastatin and ezetimibe |
Publications (1)
Publication Number | Publication Date |
---|---|
PL1901736T3 true PL1901736T3 (pl) | 2010-09-30 |
Family
ID=34937786
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PL06762303T PL1901736T3 (pl) | 2005-07-06 | 2006-06-30 | Kompozycja farmaceutyczna zawierająca symwastatynę i ezetymib |
Country Status (17)
Country | Link |
---|---|
US (1) | US8921352B2 (pl) |
EP (2) | EP1741427A1 (pl) |
AT (1) | ATE464882T1 (pl) |
CA (1) | CA2614347A1 (pl) |
DE (1) | DE602006013821D1 (pl) |
DK (1) | DK1901736T3 (pl) |
EA (1) | EA013266B1 (pl) |
ES (1) | ES2341731T3 (pl) |
HR (1) | HRP20100282T1 (pl) |
NO (1) | NO340496B1 (pl) |
PL (1) | PL1901736T3 (pl) |
PT (1) | PT1901736E (pl) |
RS (1) | RS51338B (pl) |
SI (1) | SI1901736T1 (pl) |
UA (1) | UA90521C2 (pl) |
WO (1) | WO2007003365A1 (pl) |
ZA (1) | ZA200800111B (pl) |
Families Citing this family (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7871998B2 (en) | 2003-12-23 | 2011-01-18 | Astrazeneca Ab | Diphenylazetidinone derivatives possessing cholesterol absorption inhibitory activity |
UY29607A1 (es) | 2005-06-20 | 2007-01-31 | Astrazeneca Ab | Compuestos quimicos |
SA06270191B1 (ar) | 2005-06-22 | 2010-03-29 | استرازينيكا ايه بي | مشتقات من 2- أزيتيدينون جديدة باعتبارها مثبطات لامتصاص الكوليسترول لعلاج حالات فرط نسبة الدهون في الدم |
AR057072A1 (es) | 2005-06-22 | 2007-11-14 | Astrazeneca Ab | Compuestos quimicos derivados de 2-azetidinona, formulacion farmaceutica y un proceso de preparacion del compuesto |
AR060623A1 (es) | 2006-04-27 | 2008-07-02 | Astrazeneca Ab | Compuestos derivados de 2-azetidinona y un metodo de preparacion |
WO2008101723A2 (en) * | 2007-02-23 | 2008-08-28 | Krka | Pharmaceutical composition containing a cholesterol absorption inhibitor |
WO2009024889A2 (en) * | 2007-08-21 | 2009-02-26 | Ranbaxy Laboratories Limited | Pharmaceutical composition comprising a hmg-coa reductase inhibitor and ezetimibe |
CA2708159C (en) | 2007-12-10 | 2016-01-26 | Ratiopharm Gmbh | Pharmaceutical formulation comprising ezetimibe |
EP2231118B2 (en) * | 2007-12-17 | 2017-05-17 | KRKA, tovarna zdravil, d.d., Novo mesto | Suspension comprising non-micronized ezetimibe micro-particles |
TR200806300A2 (tr) * | 2008-08-22 | 2010-03-22 | B�Lg�� Mahmut | Çözünürlük artırıcı farmasötlk formulasyon |
TR200806302A2 (tr) * | 2008-08-22 | 2010-03-22 | Bi̇lgi̇ç Mahmut | Çözünürlük ve stabilite artırıcı farmasötik formülasyon. |
MX344885B (es) * | 2008-11-10 | 2017-01-10 | Psicofarma S A De C V | Proceso para la obtencion de una composicion de rosuvastatina calcica y producto obtenido. |
EP2204170A1 (en) * | 2008-12-01 | 2010-07-07 | LEK Pharmaceuticals D.D. | Pharmaceutical composition comprising ezetimibe and simvastatin |
EP2216016A1 (en) * | 2009-02-06 | 2010-08-11 | LEK Pharmaceuticals d.d. | Process for the preparation of a pharmaceutical composition comprising ezetimibe |
WO2011002424A2 (en) | 2009-07-02 | 2011-01-06 | Bilgic Mahmut | Solubility and stability enchancing pharmaceutical formulation |
WO2011002422A2 (en) * | 2009-07-02 | 2011-01-06 | Bilgic Mahmut | Solubility enhancing pharmaceutical formulation |
EP2448919A2 (en) * | 2009-07-02 | 2012-05-09 | Mahmut Bilgic | Solubility and stability enchancing pharmaceutical formulation |
EP2368543A1 (en) | 2010-03-25 | 2011-09-28 | KRKA, tovarna zdravil, d.d., Novo mesto | Method of preparing a granulated pharmaceutical composition comprising simvastatin and/or ezetimibe |
EP2468258A1 (en) | 2010-12-22 | 2012-06-27 | LEK Pharmaceuticals d.d. | Process for the preparation of a pharmaceutical composition comprising a low soluble pharmaceutically active ingredient |
AR086675A1 (es) * | 2011-06-14 | 2014-01-15 | Merck Sharp & Dohme | Composiciones farmaceuticas de combinaciones de inhibidores de la dipeptidil peptidasa-4 con simvastatina |
CN102266323B (zh) * | 2011-08-04 | 2013-03-27 | 海南锦瑞制药股份有限公司 | 依折麦布和辛伐他汀组合物及其制备方法 |
KR102578578B1 (ko) * | 2016-02-03 | 2023-09-14 | 삼성전자주식회사 | 암모니아수 내의 불순물 검출방법 |
JP7115825B2 (ja) * | 2017-06-28 | 2022-08-09 | 日医工株式会社 | エゼチミブ含有経口製剤及びその製造方法 |
JP2019014700A (ja) * | 2017-07-11 | 2019-01-31 | 大原薬品工業株式会社 | エゼチミブ含有口腔内崩壊錠及びその製造方法 |
PL425975A1 (pl) * | 2018-06-19 | 2020-01-02 | Invest Bielany Spółka Z Ograniczoną Odpowiedzialnością | Złożona kompozycja farmaceutyczna do leczenia dyslipidemii i sposób jej wytwarzania |
WO2022023206A1 (en) * | 2020-07-27 | 2022-02-03 | Krka, D.D., Novo Mesto | Bilayer tablet comprising ezetimibe and atorvastatin |
CN115227659B (zh) * | 2022-08-19 | 2023-05-02 | 北京百奥药业有限责任公司 | 一种依折麦布辛伐他汀组合物及其制备方法 |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU548996B2 (en) | 1980-02-04 | 1986-01-09 | Merck & Co., Inc. | Tetrahydro-2h-pyran-2-one derivatives |
US4820850A (en) | 1987-07-10 | 1989-04-11 | Merck & Co., Inc. | Process for α-C-alkylation of the 8-acyl group on mevinolin and analogs thereof |
US4916239A (en) | 1988-07-19 | 1990-04-10 | Merck & Co., Inc. | Process for the lactonization of mevinic acids and analogs thereof |
US5631365A (en) * | 1993-09-21 | 1997-05-20 | Schering Corporation | Hydroxy-substituted azetidinone compounds useful as hypocholesterolemic agents |
US6235311B1 (en) * | 1998-03-18 | 2001-05-22 | Bristol-Myers Squibb Company | Pharmaceutical composition containing a combination of a statin and aspirin and method |
ATE374641T1 (de) * | 2001-01-26 | 2007-10-15 | Schering Corp | Kombinationen vom ppar-aktivator fenofibrat mit dem hemmer der sterol-absorption ezetimibe zur behandlung von kardiovaskulären indikationen |
EP1241110A1 (en) * | 2001-03-16 | 2002-09-18 | Pfizer Products Inc. | Dispensing unit for oxygen-sensitive drugs |
US6669955B2 (en) * | 2001-08-28 | 2003-12-30 | Longwood Pharmaceutical Research, Inc. | Combination dosage form containing individual dosage units of a cholesterol-lowering agent, an inhibitor of the renin-angiotensin system, and aspirin |
AU2002353659A1 (en) * | 2001-12-18 | 2003-07-15 | Synthon B.V. | Simvastatin dosage forms |
AR040588A1 (es) * | 2002-07-26 | 2005-04-13 | Schering Corp | Formulacion farmaceutica que comprende un inhibidor de la absorcion del colesterol y un inhibidor de una hmg- co a reductasa |
SI21400A (sl) * | 2003-02-12 | 2004-08-31 | LEK farmacevtska družba d.d. | Stabilna farmacevtska oblika z inhibitorjem HMG-CoA reduktaze |
AU2003259547A1 (en) | 2003-07-31 | 2005-02-14 | Hetero Drugs Limited | Ezetimibe polymorphs |
DE602004010817T2 (de) * | 2003-08-05 | 2008-12-11 | Zentiva, A.S. | Verfahren zur stabilisierung von atorvastatin |
US20060223882A1 (en) * | 2005-03-23 | 2006-10-05 | Venkataraman Sundaram | Amorphous simvastatin |
-
2005
- 2005-07-06 EP EP05014680A patent/EP1741427A1/en not_active Withdrawn
-
2006
- 2006-06-30 US US11/994,782 patent/US8921352B2/en not_active Expired - Fee Related
- 2006-06-30 EP EP06762303A patent/EP1901736B1/en active Active
- 2006-06-30 SI SI200630707T patent/SI1901736T1/sl unknown
- 2006-06-30 CA CA002614347A patent/CA2614347A1/en not_active Abandoned
- 2006-06-30 DE DE602006013821T patent/DE602006013821D1/de active Active
- 2006-06-30 PL PL06762303T patent/PL1901736T3/pl unknown
- 2006-06-30 RS RSP-2010/0213A patent/RS51338B/en unknown
- 2006-06-30 UA UAA200714923A patent/UA90521C2/uk unknown
- 2006-06-30 PT PT06762303T patent/PT1901736E/pt unknown
- 2006-06-30 DK DK06762303.3T patent/DK1901736T3/da active
- 2006-06-30 WO PCT/EP2006/006369 patent/WO2007003365A1/en active Application Filing
- 2006-06-30 ES ES06762303T patent/ES2341731T3/es active Active
- 2006-06-30 EA EA200702416A patent/EA013266B1/ru not_active IP Right Cessation
- 2006-06-30 AT AT06762303T patent/ATE464882T1/de active
-
2008
- 2008-01-04 ZA ZA200800111A patent/ZA200800111B/xx unknown
- 2008-02-04 NO NO20080627A patent/NO340496B1/no not_active IP Right Cessation
-
2010
- 2010-05-21 HR HR20100282T patent/HRP20100282T1/hr unknown
Also Published As
Publication number | Publication date |
---|---|
CA2614347A1 (en) | 2007-01-11 |
EA013266B1 (ru) | 2010-04-30 |
NO340496B1 (no) | 2017-05-02 |
EP1901736B1 (en) | 2010-04-21 |
EP1901736A1 (en) | 2008-03-26 |
US8921352B2 (en) | 2014-12-30 |
ZA200800111B (en) | 2008-12-31 |
HRP20100282T1 (hr) | 2010-07-31 |
PT1901736E (pt) | 2010-05-31 |
EP1741427A1 (en) | 2007-01-10 |
EA200702416A1 (ru) | 2008-04-28 |
SI1901736T1 (sl) | 2010-08-31 |
US20080300233A1 (en) | 2008-12-04 |
RS51338B (en) | 2011-02-28 |
DK1901736T3 (da) | 2010-08-16 |
UA90521C2 (uk) | 2010-05-11 |
DE602006013821D1 (en) | 2010-06-02 |
ES2341731T3 (es) | 2010-06-25 |
WO2007003365A1 (en) | 2007-01-11 |
NO20080627L (no) | 2008-04-02 |
ATE464882T1 (de) | 2010-05-15 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ZA200800111B (en) | Pharmaceutical composition comprising simvastatin and ezetimibe | |
EA201390409A1 (ru) | Составы с низкой дозой панкрелипазы и кишечно-растворимым покрытием | |
WO2007051811A3 (en) | Pharmaceutical use of substituted amides | |
MY147373A (en) | Piperazine derivatives as antimalarial agents | |
WO2010030180A3 (en) | Peptide formulations and uses thereof | |
UA94901C2 (ru) | Антибактериальные производные пиперидина | |
MY150958A (en) | Compounds for the treatment of multi-drug resistant bacterial infections | |
HK1084582A1 (en) | Stable solid medicinal composition for oral administration | |
BR0314612A (pt) | Composição farmacêutica estabilizada, contendo excipientes básicos | |
WO2007112000A3 (en) | Treatment of pain | |
EP2392322A3 (en) | Dosing regimes for trans-clomiphene | |
WO2007112272A3 (en) | Formulations of low dose diclofenac and beta-cyclodextrin | |
EP2648704B1 (en) | Anti-microbial composition | |
IL192611A0 (en) | Biologically active composition comprising ethylcellulose | |
NZ591204A (en) | Pharmaceutical compositions and methods for stabilizing the same | |
WO2007062333A3 (en) | New pleuromutilin derivative and its use | |
EP2801359A3 (en) | The use of nicotine for the treatment of sepsis in humans caused by antibiotic | |
EP1713439B1 (en) | Pharmaceutical preparation for the oral cavity | |
EA201100104A1 (ru) | Фармацевтическая композиция, содержащая статин | |
BRPI0407529A (pt) | uso de r-10-hidróxi-10,11-dihidro-carbamazepina em dor neuropática | |
WO2007138233A3 (fr) | Utilisation du zatosetron pour le traitement de la rosacee | |
MY174362A (en) | Nephelium lappaceum extracts for cosmeceutical and nutraceutical applications | |
CY1110814T1 (el) | Νεα υποκατεστημενα αρυλοεξαδιενικα οξεα και εστερες αυτων τα οποια μπορουν να χρησιμοποιηθουν για την αγωγη και προληψη του διαβητη, δυσλιπιδαιμιας και αθηροσκληρωσης, φαρμακευτικες συνθεσεις που τα περιλαμβανουν και διεργασιες για την παρασκευη αυτων | |
HRP20090102T3 (en) | Improved pharmaceutical composition containing ace inhibitor and method for the preparation thereof | |
MX2009002254A (es) | Dosis de bifeprunox para tratar esquizofrenia. |