PL1885363T3 - Zastosowanie 3,11b-cis-dihydrotetrabenzyny do leczenia objawów choroby Huntingtona - Google Patents

Zastosowanie 3,11b-cis-dihydrotetrabenzyny do leczenia objawów choroby Huntingtona

Info

Publication number
PL1885363T3
PL1885363T3 PL06764942T PL06764942T PL1885363T3 PL 1885363 T3 PL1885363 T3 PL 1885363T3 PL 06764942 T PL06764942 T PL 06764942T PL 06764942 T PL06764942 T PL 06764942T PL 1885363 T3 PL1885363 T3 PL 1885363T3
Authority
PL
Poland
Prior art keywords
dihydrotetrabenazine
huntington
cis
symptoms
disease
Prior art date
Application number
PL06764942T
Other languages
English (en)
Inventor
Robert Tridgett
T Filloux
Original Assignee
Biovail Laboratories Int Barbados Srl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biovail Laboratories Int Barbados Srl filed Critical Biovail Laboratories Int Barbados Srl
Publication of PL1885363T3 publication Critical patent/PL1885363T3/pl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4375Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having nitrogen as a ring heteroatom, e.g. quinolizines, naphthyridines, berberine, vincamine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/473Quinolines; Isoquinolines ortho- or peri-condensed with carbocyclic ring systems, e.g. acridines, phenanthridines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Psychology (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
PL06764942T 2005-07-14 2006-07-13 Zastosowanie 3,11b-cis-dihydrotetrabenzyny do leczenia objawów choroby Huntingtona PL1885363T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB0514501.6A GB0514501D0 (en) 2005-07-14 2005-07-14 Pharmaceutical compounds
PCT/GB2006/002593 WO2007007105A1 (en) 2005-07-14 2006-07-13 Use of 3,1ib-cis-dihydrotetrabenazine for the treatment of symptons of huntington' s disease
EP06764942A EP1885363B1 (en) 2005-07-14 2006-07-13 Use of 3,11b-cis-dihydrotetrabenazine for the treatment of symptoms of huntington' s disease

Publications (1)

Publication Number Publication Date
PL1885363T3 true PL1885363T3 (pl) 2009-05-29

Family

ID=34897233

Family Applications (1)

Application Number Title Priority Date Filing Date
PL06764942T PL1885363T3 (pl) 2005-07-14 2006-07-13 Zastosowanie 3,11b-cis-dihydrotetrabenzyny do leczenia objawów choroby Huntingtona

Country Status (24)

Country Link
US (1) US20080319000A1 (pl)
EP (2) EP1885363B1 (pl)
JP (1) JP2009501202A (pl)
KR (1) KR20080030666A (pl)
CN (1) CN101282726A (pl)
AT (2) ATE409481T1 (pl)
AU (1) AU2006268098B2 (pl)
CA (1) CA2615077A1 (pl)
CY (1) CY1108653T1 (pl)
DE (1) DE602006002982D1 (pl)
DK (1) DK1885363T3 (pl)
ES (1) ES2314931T3 (pl)
GB (1) GB0514501D0 (pl)
HK (1) HK1111085A1 (pl)
HR (1) HRP20080677T3 (pl)
ME (1) ME01629B (pl)
NZ (1) NZ565522A (pl)
PL (1) PL1885363T3 (pl)
PT (1) PT1885363E (pl)
RS (1) RS50626B (pl)
RU (1) RU2409365C2 (pl)
SI (1) SI1885363T1 (pl)
WO (1) WO2007007105A1 (pl)
ZA (1) ZA200800905B (pl)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2410947B (en) * 2004-02-11 2008-09-17 Cambridge Lab Ltd Pharmaceutical compounds
GB0516168D0 (en) * 2005-08-05 2005-09-14 Cambridge Lab Ireland Ltd Pharmaceutical compounds
PT2081929E (pt) 2006-11-08 2013-04-15 Neurocrine Biosciences Inc Compostos de 3-isobutil-9,10-dimetoxi- 1,3,4,6,7,11b-hexahidro-2h-pirido[2,1-a]isoquinolin- 2-ol substituídos e métodos com estes relacionados
GB0810857D0 (en) * 2008-06-13 2008-07-23 Cambridge Lab Ireland Ltd Pharmaceutical compounds
GB2462611A (en) * 2008-08-12 2010-02-17 Cambridge Lab Pharmaceutical composition comprising tetrabenazine
US20110053866A1 (en) * 2008-08-12 2011-03-03 Biovail Laboratories International (Barbados) S.R.L. Pharmaceutical compositions
US20120208773A1 (en) * 2008-08-12 2012-08-16 Valeant International (Barbados) Srl Pharmaceutical compositions with tetrabenazine
GB2463451A (en) * 2008-09-08 2010-03-17 Cambridge Lab 3, 11b cis-dihydrotetrabenazine compounds for use in the treatment of dementia
GB2463452A (en) * 2008-09-08 2010-03-17 Cambridge Lab Desmethyl derivatives of tetrabenazine and pharmaceutical compositions thereof
GB2463283A (en) * 2008-09-08 2010-03-10 Cambridge Lab 3,11b-cis-dihydrotetrabenazine for use in treating asthma
CA2771539A1 (en) * 2009-08-12 2011-02-17 Valeant International (Barbados) Srl Pharmaceutical compositions with tetrabenzine
WO2011153157A2 (en) * 2010-06-01 2011-12-08 Auspex Pharmaceutical, Inc. Benzoquinolone inhibitors of vmat2
WO2012095548A2 (es) 2011-01-13 2012-07-19 Centro De Investigación Biomédica En Red De Enfermedades Neurodegenerativas (Ciberned) Compuestos para el tratamiento de enfermedades neurodegenerativas
GB201705303D0 (en) 2017-04-01 2017-05-17 Adeptio Pharmaceuticals Ltd Pharmaceutical compositions
GB201705306D0 (en) 2017-04-01 2017-05-17 Adeptio Pharmaceuticals Ltd Pharmaceutical compositions
EP3606530A2 (en) * 2017-04-01 2020-02-12 Adeptio Pharmaceuticals Limited Dihydrotetrabenazine for use in the treatment a movement disorder
GB201705302D0 (en) 2017-04-01 2017-05-17 Adeptio Pharmaceuticals Ltd Pharmaceutical compositions
GB201705304D0 (en) 2017-04-01 2017-05-17 Adeptio Pharmaceuticals Ltd Pharmaceutical compositions
GB201808464D0 (en) * 2018-05-23 2018-07-11 Adeptio Pharmaceuticals Ltd Pharmaceutical compounds for use in treating huntington's disease
JP2022541021A (ja) * 2019-07-16 2022-09-21 ラッシュ・ユニバーシティ・メディカル・センター 神経変性障害を治療するためのベンゾエート含有組成物の使用

Family Cites Families (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3132147A (en) * 1964-05-05
US2954382A (en) * 1960-09-27 Xpreparation of hexahydrobenzoquinol-
US3009918A (en) * 1961-11-21 Chz ch
US3159638A (en) * 1964-12-01 Xcha-chj
US3053845A (en) * 1962-09-11 Benzofykedocolines
US3314966A (en) * 1967-04-18 Substituted benzo[a]quinolizines
US3095419A (en) * 1963-06-25 Process for preparing z-oxo-j-
US2830993A (en) * 1958-04-15 Quinolizine derivatives
US3123609A (en) * 1964-03-03 Benzo
US3209005A (en) * 1965-09-28 Hexahydro-llbh-benzo[a] quinolizines and processes therefor
US2843591A (en) * 1958-07-15 Method for preparing same
US3079395A (en) * 1963-02-26 Novel z-oxq-benzoquinoliaine
US3045021A (en) * 1959-09-24 1962-07-17 Hoffmann La Roche Preparation of substituted 2-oxobenzoquinolizines
GB999092A (en) * 1959-11-24 1965-07-21 Wellcome Found Method for making benzo(a)-quinolizine derivatives
US3375254A (en) * 1961-09-29 1968-03-26 Burroughs Wellcome Co Manufacture of 1, 2, 3, 4, 6, 7-hexahydro-2-oxo-11bh-benzo(a)quinolizines
US3105079A (en) * 1961-12-29 1963-09-24 Pfizer & Co C 10-aminobenzopyridocolines
US3390152A (en) * 1965-10-21 1968-06-25 Abbott Lab 9, 10-alkoxy-3-alkyl-2, 2-(dithiosubstituted)-benzoquinolizines
JPS4836303B1 (pl) * 1968-12-27 1973-11-02
US3635986A (en) * 1969-12-22 1972-01-18 Miles Lab 2-substituted amino-hexahydrobenzo(a)quinolizines
YU264675A (en) * 1974-10-23 1982-05-31 Chinoin Gyogyszer Es Vegyeszet Process for obtaining benzo (a)-quinolizidine derivatives
GB1513824A (en) * 1975-05-22 1978-06-14 Wyeth John & Brother Ltd 1,3,4,6,7,11b-hexahydro-2h-benzo(a)quinolizine derivative
US4133812A (en) * 1975-11-21 1979-01-09 Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara Rt. Process for producing benzo (a) quinolizine derivatives
US4304913A (en) * 1978-11-20 1981-12-08 Miles Laboratories, Inc. Trans-2-substituted-amido-hexahydrobenzo [A]quinolizines
US4353656A (en) * 1980-10-14 1982-10-12 Xerox Corporation Moving coil, multiple energy print hammer system including a closed loop servo
US4778054A (en) * 1982-10-08 1988-10-18 Glaxo Group Limited Pack for administering medicaments to patients
US4811731A (en) * 1985-07-30 1989-03-14 Glaxo Group Limited Devices for administering medicaments to patients
GB9004781D0 (en) * 1990-03-02 1990-04-25 Glaxo Group Ltd Device
US6087376A (en) * 1997-02-05 2000-07-11 University Of Kentucky Research Foundation Use of lobeline compounds in the treatment of central nervous system diseases and pathologies
FR2794742B1 (fr) * 1999-06-11 2005-06-03 Sanofi Synthelabo Nouveaux derives du benzene, un procede pour leur preparation et les compositions pharmaceutiques les contenant
US6632666B2 (en) * 2000-01-14 2003-10-14 Biolife Solutions, Inc. Normothermic, hypothermic and cryopreservation maintenance and storage of cells, tissues and organs in gel-based media
WO2001079198A1 (en) * 2000-04-18 2001-10-25 Agouron Pharmaceuticals, Inc. Pyrazoles for inhibiting protein kinase
CA2673334C (en) * 2003-06-16 2013-11-12 Andrx Pharmaceuticals, Llc Oral extended-release composition
GB2410947B (en) * 2004-02-11 2008-09-17 Cambridge Lab Ltd Pharmaceutical compounds
WO2006053067A2 (en) * 2004-11-09 2006-05-18 Prestwick Pharmaceuticals, Inc. Combination of amantadine and a tetrabenazine compound for treating hyperkinetic disorders
KR100682506B1 (ko) * 2005-01-18 2007-02-15 (주)젠크로스 프라지콴텔, 또는 이의 염을 포함하는 약학 조성물
GB0516168D0 (en) * 2005-08-05 2005-09-14 Cambridge Lab Ireland Ltd Pharmaceutical compounds
US20110053866A1 (en) * 2008-08-12 2011-03-03 Biovail Laboratories International (Barbados) S.R.L. Pharmaceutical compositions
GB2462611A (en) * 2008-08-12 2010-02-17 Cambridge Lab Pharmaceutical composition comprising tetrabenazine
GB2463452A (en) * 2008-09-08 2010-03-17 Cambridge Lab Desmethyl derivatives of tetrabenazine and pharmaceutical compositions thereof
GB2463283A (en) * 2008-09-08 2010-03-10 Cambridge Lab 3,11b-cis-dihydrotetrabenazine for use in treating asthma
GB2463451A (en) * 2008-09-08 2010-03-17 Cambridge Lab 3, 11b cis-dihydrotetrabenazine compounds for use in the treatment of dementia

Also Published As

Publication number Publication date
ES2314931T3 (es) 2009-03-16
US20080319000A1 (en) 2008-12-25
PT1885363E (pt) 2009-01-08
NZ565522A (en) 2010-04-30
EP2027861A1 (en) 2009-02-25
RS50626B (sr) 2010-06-30
ATE522215T1 (de) 2011-09-15
ATE409481T1 (de) 2008-10-15
DE602006002982D1 (de) 2008-11-13
JP2009501202A (ja) 2009-01-15
KR20080030666A (ko) 2008-04-04
EP1885363B1 (en) 2008-10-01
CY1108653T1 (el) 2014-04-09
RU2008105590A (ru) 2009-08-20
SI1885363T1 (sl) 2009-02-28
RU2409365C2 (ru) 2011-01-20
CA2615077A1 (en) 2007-01-18
GB0514501D0 (en) 2005-08-24
CN101282726A (zh) 2008-10-08
WO2007007105A1 (en) 2007-01-18
HRP20080677T3 (en) 2009-02-28
AU2006268098B2 (en) 2011-02-17
ZA200800905B (en) 2010-04-28
EP2027861B1 (en) 2011-08-31
EP1885363A1 (en) 2008-02-13
AU2006268098A1 (en) 2007-01-18
ME01629B (me) 2010-06-30
HK1111085A1 (en) 2008-08-01
DK1885363T3 (da) 2008-12-08

Similar Documents

Publication Publication Date Title
ZA200800905B (en) Use of 3,11B-CIS-Dihydrotetrabenazine for the treatment of symptoms of huntington's disease
CY1121408T1 (el) Προληψη και θεραπεια συνουκλεϊνοπαθειας και αμυλοειδοπαθειας
HK1105893A1 (en) Compounds, compositions and methods of inhibiting a-synuclein toxicity
WO2006091693A3 (en) Extending time to disease progression or survival in cancer patients using a her dimerization inhibitor
ATE534391T1 (de) 3,11b-cis-dihydrotetrabenazin zur behandlung von psychosen
IL176393A0 (en) Patterned laser treatment of the retina
WO2007012061A3 (en) Prevention and treatment of synucleinopathic and amyloidogenic disease
EA200601837A1 (ru) Бензоксазины для лечения заболеваний дыхательных путей
ES2414872T8 (es) Terapia combinada para la prevención o tratamiento de la enfermedad de Alzheimer y kit correspondiente
HK1162931A1 (en) Improved modalities for the treatment of degenerative diseases of the retina
IL189104A (en) Pharmaceutical preparation containing lasalazide or sodium balasalazide for use in the treatment of gastrointestinal disorders.
WO2004004609A3 (fr) Immobilisateur dynamique elastique pour doigts ou orteils
WO2008016640A3 (en) Use of poloxamer for the prevention and/or treatment of heart failure
GB0521716D0 (en) Modulation of 11beta-hydroxysteriod dehydrogenase 1 expression for the treatment of ocular diseases
HK1110768A1 (en) 5,6,7-trihydroxyheptanoic acid and analogs for the treatment of ocular diseases and diseases associated with hyperproliferative and angiogenic responses
PT2366393E (pt) Roflumilaste para o tratamento da hipertensão pulmonar
AU2003303217A8 (en) Use of substituted 2,5-diamidoindoles for the treatment of urological diseases
DK1732648T3 (da) Sygdomsbehandling
IL191208A (en) Use of phenofibrate or its derivative for the preparation of a drug for the treatment of diabetic retinopathy
WO2006062973A3 (en) Use of organic compounds