PL1858851T3 - Sposób otrzymywania amorficznej lerkanidypiny - Google Patents

Sposób otrzymywania amorficznej lerkanidypiny

Info

Publication number
PL1858851T3
PL1858851T3 PL05817765T PL05817765T PL1858851T3 PL 1858851 T3 PL1858851 T3 PL 1858851T3 PL 05817765 T PL05817765 T PL 05817765T PL 05817765 T PL05817765 T PL 05817765T PL 1858851 T3 PL1858851 T3 PL 1858851T3
Authority
PL
Poland
Prior art keywords
preparing method
amorphous lercanidipine
lercanidipine
amorphous
preparing
Prior art date
Application number
PL05817765T
Other languages
English (en)
Inventor
So Mi Choo
Hong Joo Ha
Jung Gi An
Won Jung Lee
S G Lee
Young-Seok Byun
Young Il Moon
Original Assignee
Recordati Ireland Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Recordati Ireland Ltd filed Critical Recordati Ireland Ltd
Publication of PL1858851T3 publication Critical patent/PL1858851T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/44221,4-Dihydropyridines, e.g. nifedipine, nicardipine
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B63/00Purification; Separation; Stabilisation; Use of additives
    • C07B63/04Use of additives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
PL05817765T 2004-10-27 2005-10-26 Sposób otrzymywania amorficznej lerkanidypiny PL1858851T3 (pl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
KR20040086179 2004-10-27
KR1020050031041A KR100651212B1 (ko) 2004-10-27 2005-04-14 무정형 레르카니디핀의 제조방법
EP05817765.0A EP1858851B1 (en) 2004-10-27 2005-10-26 Preparing method for amorphous lercanidipine
PCT/KR2005/003576 WO2006046830A1 (en) 2004-10-27 2005-10-26 Preparing method for amorphous lercanidipine

Publications (1)

Publication Number Publication Date
PL1858851T3 true PL1858851T3 (pl) 2015-11-30

Family

ID=36228043

Family Applications (1)

Application Number Title Priority Date Filing Date
PL05817765T PL1858851T3 (pl) 2004-10-27 2005-10-26 Sposób otrzymywania amorficznej lerkanidypiny

Country Status (13)

Country Link
EP (1) EP1858851B1 (pl)
KR (1) KR100651212B1 (pl)
CA (1) CA2624934C (pl)
CY (1) CY1116752T1 (pl)
DK (1) DK1858851T3 (pl)
ES (1) ES2546930T3 (pl)
HR (1) HRP20150989T1 (pl)
HU (1) HUE025506T2 (pl)
PL (1) PL1858851T3 (pl)
PT (1) PT1858851E (pl)
RS (1) RS54174B1 (pl)
SI (1) SI1858851T1 (pl)
WO (1) WO2006046830A1 (pl)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR052918A1 (es) 2005-02-25 2007-04-11 Recordati Ireland Ltd Clorhidrato de lercanidipina amorfo
CN101868442A (zh) * 2007-03-05 2010-10-20 阿克塔维什集团Ptc公司 盐酸乐卡地平多晶型物和1,1,n-三甲基-n-(3,3-二苯基丙基)-2-氨基乙酰醋酸乙酯的改进制法
CN102531999B (zh) * 2011-12-16 2014-02-26 华润赛科药业有限责任公司 无定形盐酸乐卡地平及其制备方法
CN102558032B (zh) * 2011-12-16 2014-02-26 华润赛科药业有限责任公司 一种无定形盐酸乐卡地平及其制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8403866D0 (en) 1984-02-14 1984-03-21 Recordati Chem Pharm Diphenylalkylaminoalkyl esters
US5696139A (en) 1995-05-12 1997-12-09 Recordati S.A., Chemical And Pharmaceutical Company Use of S-enantiomers of 1,4-dihydropyridine derivatives for treating heart failure
US5767136A (en) 1995-05-12 1998-06-16 Recordati, S.A. Chemical And Pharmaceutical Company 1,4-Dihydropyridines useful for prevention or reduction of atherosclerotic lesions on arterial walls
US6852737B2 (en) * 2001-08-06 2005-02-08 Recordati Ireland Limited Crude and crystalline forms of lercanidipine hydrochloride
ITMI20011727A1 (it) 2001-08-06 2003-02-06 Recordati Ind Chimica E Farma Solvati della lercanidipina cloridrato e nuove forme cristalline della lercanidipina cloridrato ottenute da essi
AR053023A1 (es) * 2005-02-25 2007-04-18 Recordati Ireland Ltd Base libre de lercanidipina, metodos para su preparacion y composiciones farmaceuticas que las contienen

Also Published As

Publication number Publication date
CA2624934C (en) 2013-04-23
HRP20150989T1 (hr) 2015-10-23
RS54174B1 (en) 2015-12-31
KR20060045705A (ko) 2006-05-17
ES2546930T3 (es) 2015-09-30
WO2006046830A1 (en) 2006-05-04
SI1858851T1 (sl) 2015-11-30
KR100651212B1 (ko) 2006-12-01
PT1858851E (pt) 2015-10-12
CY1116752T1 (el) 2017-03-15
CA2624934A1 (en) 2006-05-04
EP1858851A4 (en) 2009-12-30
DK1858851T3 (en) 2015-09-14
HUE025506T2 (en) 2016-02-29
EP1858851B1 (en) 2015-06-24
EP1858851A1 (en) 2007-11-28

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