PL1778265T3 - Związki guanylohydrazonowe, kompozycje, sposoby wytwarzania i stosowania - Google Patents

Związki guanylohydrazonowe, kompozycje, sposoby wytwarzania i stosowania

Info

Publication number
PL1778265T3
PL1778265T3 PL05785277T PL05785277T PL1778265T3 PL 1778265 T3 PL1778265 T3 PL 1778265T3 PL 05785277 T PL05785277 T PL 05785277T PL 05785277 T PL05785277 T PL 05785277T PL 1778265 T3 PL1778265 T3 PL 1778265T3
Authority
PL
Poland
Prior art keywords
compositions
making
methods
guanylhydrazone compounds
guanylhydrazone
Prior art date
Application number
PL05785277T
Other languages
English (en)
Inventor
Thais M Sielecki-Dzurdz
Original Assignee
Ferring Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ferring Bv filed Critical Ferring Bv
Publication of PL1778265T3 publication Critical patent/PL1778265T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C281/00Derivatives of carbonic acid containing functional groups covered by groups C07C269/00 - C07C279/00 in which at least one nitrogen atom of these functional groups is further bound to another nitrogen atom not being part of a nitro or nitroso group
    • C07C281/16Compounds containing any of the groups, e.g. aminoguanidine
    • C07C281/18Compounds containing any of the groups, e.g. aminoguanidine the other nitrogen atom being further doubly-bound to a carbon atom, e.g. guanylhydrazones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00Carboxylic acid amides
    • C07C233/01Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/30Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by doubly-bound oxygen atoms
    • C07C233/33Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by doubly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D261/00Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/02Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
    • C07D261/06Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
    • C07D261/08Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/38Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Medicinal Preparation (AREA)
PL05785277T 2004-08-17 2005-08-17 Związki guanylohydrazonowe, kompozycje, sposoby wytwarzania i stosowania PL1778265T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US60199204P 2004-08-17 2004-08-17
EP05785277.4A EP1778265B1 (en) 2004-08-17 2005-08-17 Guanylhydrazone compounds, compositions, methods of making and using
PCT/US2005/029301 WO2006023586A2 (en) 2004-08-17 2005-08-17 Guanylhydrazone compounds, compositions, methods of making and using

Publications (1)

Publication Number Publication Date
PL1778265T3 true PL1778265T3 (pl) 2013-10-31

Family

ID=35968147

Family Applications (1)

Application Number Title Priority Date Filing Date
PL05785277T PL1778265T3 (pl) 2004-08-17 2005-08-17 Związki guanylohydrazonowe, kompozycje, sposoby wytwarzania i stosowania

Country Status (13)

Country Link
US (3) US7291647B2 (pl)
EP (2) EP2543661B1 (pl)
JP (2) JP5198863B2 (pl)
CN (2) CN102936212A (pl)
AU (1) AU2005277456B2 (pl)
BR (1) BRPI0514452A8 (pl)
CA (1) CA2577156C (pl)
DK (1) DK1778265T3 (pl)
ES (1) ES2422425T3 (pl)
MX (1) MX2007001928A (pl)
PL (1) PL1778265T3 (pl)
PT (1) PT1778265E (pl)
WO (1) WO2006023586A2 (pl)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2007001928A (es) * 2004-08-17 2007-04-17 Cytokine Pharmasciences Inc Metodos para producir y utilizar los compuestos o composiciones de guanilhidrazona.
CA2655632A1 (en) * 2006-06-23 2008-01-03 The Feinstein Institute For Medical Research Inhibitors of a.beta. and synuclein aggregation
RU2477271C2 (ru) * 2011-01-12 2013-03-10 Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Кабардино-Балкарский государственный университет им. Х.М. Бербекова" (КБГУ) Моно- и дикетимины на основе 4,4'-диацетилдифенилоксида и гуанидина и способ их получения
CN109580873A (zh) * 2018-12-27 2019-04-05 湖北航天化学技术研究所 一种三氨基硝酸胍纯度的测定方法
CN116102468B (zh) * 2023-02-22 2024-07-09 中国科学技术大学 靶向人脂质运载蛋白2的先导化合物或其药学上可接受的盐及其制备方法与应用
WO2025045826A1 (en) * 2023-08-25 2025-03-06 The Cultivated B. Gmbh Compounds for activation of fgfr1 signaling

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH474486A (de) * 1965-11-19 1969-06-30 Ciba Geigy Verfahren zur Herstellung neuer Diphenylharnstoffe
IT1055433B (it) * 1976-02-23 1981-12-21 Anic Spa Metodo per la purificazione di acqua di scarico contenenti composti organici di carattere anioni co e mezzi adatti allo scopo
US5272165A (en) * 1984-03-19 1993-12-21 The Rockefeller University 2-alkylidene-aminoguanidines and methods of use therefor
US7425543B2 (en) * 1992-11-16 2008-09-16 The Corporation Of Mercer University Microencapsulated materials and method of making same
US5599984A (en) * 1994-01-21 1997-02-04 The Picower Institute For Medical Research Guanylhydrazones and their use to treat inflammatory conditions
US6008255A (en) * 1994-01-21 1999-12-28 The Picower Institute For Medical Research Guanylhydrazones and their use to treat inflammatory conditions
JP3823330B2 (ja) * 1994-11-09 2006-09-20 昭和電工株式会社 N−ホスホノメチルグリシンの単離方法
JP2001503775A (ja) 1996-11-15 2001-03-21 ザ ピコワー インスティテュート フォー メディカル リサーチ T細胞の活性化に関係する疾患を治療するために有用なグアニルヒドラゾン
US6319894B1 (en) 1997-01-08 2001-11-20 The Picower Institute For Medical Research Complexes and combinations of fetuin with therapeutic agents
ES2250363T3 (es) * 2000-02-02 2006-04-16 Dorian Bevec Guanilhidrazonas aromaticas farmaceuticamente activas.
WO2002000613A2 (en) * 2000-06-27 2002-01-03 Axxima Pharmaceuticals Ag Inhibitors of hepatitis b virus infection
WO2003006426A1 (en) * 2001-07-13 2003-01-23 Axxima Pharmaceuticals Ag Aromatic guanylhydrazones as effective compounds against neurodiseases
EP1435932A4 (en) * 2001-09-21 2006-12-06 Message Pharmaceuticals Inc INHIBITORS OF RNASE-P PROTEINS AS ANTIBACTERIAL COMPOUNDS
CA2476896A1 (en) * 2002-02-26 2003-09-04 North Shore-Long Island Jewish Research Institute Inhibition of inflammatory cytokine production by stimulation of brain muscarinic receptors
EP1389480A1 (en) * 2002-08-14 2004-02-18 Mondobiotech Interferon SA Therapeutical use of guanylhydrazones for the inhibition of CD83 dependent processes and dendritic cell maturation
US7244765B2 (en) * 2004-06-25 2007-07-17 Cytokine Pharmasciences, Inc Guanylhydrazone salts, compositions, processes of making and methods of using
MX2007001928A (es) * 2004-08-17 2007-04-17 Cytokine Pharmasciences Inc Metodos para producir y utilizar los compuestos o composiciones de guanilhidrazona.

Also Published As

Publication number Publication date
BRPI0514452A8 (pt) 2018-02-06
JP2008510703A (ja) 2008-04-10
CN101010094B (zh) 2013-05-22
PT1778265E (pt) 2013-08-05
CA2577156A1 (en) 2006-03-02
CA2577156C (en) 2013-11-26
JP5198863B2 (ja) 2013-05-15
EP1778265A2 (en) 2007-05-02
CN102936212A (zh) 2013-02-20
US20110144189A1 (en) 2011-06-16
BRPI0514452A (pt) 2008-06-10
WO2006023586A2 (en) 2006-03-02
CN101010094A (zh) 2007-08-01
WO2006023586A3 (en) 2007-01-04
US7863334B2 (en) 2011-01-04
US20060041002A1 (en) 2006-02-23
AU2005277456B2 (en) 2011-12-01
US7291647B2 (en) 2007-11-06
MX2007001928A (es) 2007-04-17
US20080070959A1 (en) 2008-03-20
ES2422425T3 (es) 2013-09-11
JP5551755B2 (ja) 2014-07-16
EP2543661B1 (en) 2016-12-07
JP2013100291A (ja) 2013-05-23
EP1778265A4 (en) 2010-01-06
AU2005277456A1 (en) 2006-03-02
DK1778265T3 (da) 2013-06-24
US8247455B2 (en) 2012-08-21
EP1778265B1 (en) 2013-04-24
EP2543661A1 (en) 2013-01-09

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