PL1778265T3 - Związki guanylohydrazonowe, kompozycje, sposoby wytwarzania i stosowania - Google Patents
Związki guanylohydrazonowe, kompozycje, sposoby wytwarzania i stosowaniaInfo
- Publication number
- PL1778265T3 PL1778265T3 PL05785277T PL05785277T PL1778265T3 PL 1778265 T3 PL1778265 T3 PL 1778265T3 PL 05785277 T PL05785277 T PL 05785277T PL 05785277 T PL05785277 T PL 05785277T PL 1778265 T3 PL1778265 T3 PL 1778265T3
- Authority
- PL
- Poland
- Prior art keywords
- compositions
- making
- methods
- guanylhydrazone compounds
- guanylhydrazone
- Prior art date
Links
- MXWHMTNPTTVWDM-NXOFHUPFSA-N mitoguazone Chemical class NC(N)=N\N=C(/C)\C=N\N=C(N)N MXWHMTNPTTVWDM-NXOFHUPFSA-N 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C281/00—Derivatives of carbonic acid containing functional groups covered by groups C07C269/00 - C07C279/00 in which at least one nitrogen atom of these functional groups is further bound to another nitrogen atom not being part of a nitro or nitroso group
- C07C281/16—Compounds containing any of the groups, e.g. aminoguanidine
- C07C281/18—Compounds containing any of the groups, e.g. aminoguanidine the other nitrogen atom being further doubly-bound to a carbon atom, e.g. guanylhydrazones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/30—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by doubly-bound oxygen atoms
- C07C233/33—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by doubly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
- C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
- C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
- C07D261/08—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US60199204P | 2004-08-17 | 2004-08-17 | |
| EP05785277.4A EP1778265B1 (en) | 2004-08-17 | 2005-08-17 | Guanylhydrazone compounds, compositions, methods of making and using |
| PCT/US2005/029301 WO2006023586A2 (en) | 2004-08-17 | 2005-08-17 | Guanylhydrazone compounds, compositions, methods of making and using |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL1778265T3 true PL1778265T3 (pl) | 2013-10-31 |
Family
ID=35968147
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL05785277T PL1778265T3 (pl) | 2004-08-17 | 2005-08-17 | Związki guanylohydrazonowe, kompozycje, sposoby wytwarzania i stosowania |
Country Status (13)
| Country | Link |
|---|---|
| US (3) | US7291647B2 (pl) |
| EP (2) | EP2543661B1 (pl) |
| JP (2) | JP5198863B2 (pl) |
| CN (2) | CN102936212A (pl) |
| AU (1) | AU2005277456B2 (pl) |
| BR (1) | BRPI0514452A8 (pl) |
| CA (1) | CA2577156C (pl) |
| DK (1) | DK1778265T3 (pl) |
| ES (1) | ES2422425T3 (pl) |
| MX (1) | MX2007001928A (pl) |
| PL (1) | PL1778265T3 (pl) |
| PT (1) | PT1778265E (pl) |
| WO (1) | WO2006023586A2 (pl) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX2007001928A (es) * | 2004-08-17 | 2007-04-17 | Cytokine Pharmasciences Inc | Metodos para producir y utilizar los compuestos o composiciones de guanilhidrazona. |
| CA2655632A1 (en) * | 2006-06-23 | 2008-01-03 | The Feinstein Institute For Medical Research | Inhibitors of a.beta. and synuclein aggregation |
| RU2477271C2 (ru) * | 2011-01-12 | 2013-03-10 | Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Кабардино-Балкарский государственный университет им. Х.М. Бербекова" (КБГУ) | Моно- и дикетимины на основе 4,4'-диацетилдифенилоксида и гуанидина и способ их получения |
| CN109580873A (zh) * | 2018-12-27 | 2019-04-05 | 湖北航天化学技术研究所 | 一种三氨基硝酸胍纯度的测定方法 |
| CN116102468B (zh) * | 2023-02-22 | 2024-07-09 | 中国科学技术大学 | 靶向人脂质运载蛋白2的先导化合物或其药学上可接受的盐及其制备方法与应用 |
| WO2025045826A1 (en) * | 2023-08-25 | 2025-03-06 | The Cultivated B. Gmbh | Compounds for activation of fgfr1 signaling |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH474486A (de) * | 1965-11-19 | 1969-06-30 | Ciba Geigy | Verfahren zur Herstellung neuer Diphenylharnstoffe |
| IT1055433B (it) * | 1976-02-23 | 1981-12-21 | Anic Spa | Metodo per la purificazione di acqua di scarico contenenti composti organici di carattere anioni co e mezzi adatti allo scopo |
| US5272165A (en) * | 1984-03-19 | 1993-12-21 | The Rockefeller University | 2-alkylidene-aminoguanidines and methods of use therefor |
| US7425543B2 (en) * | 1992-11-16 | 2008-09-16 | The Corporation Of Mercer University | Microencapsulated materials and method of making same |
| US5599984A (en) * | 1994-01-21 | 1997-02-04 | The Picower Institute For Medical Research | Guanylhydrazones and their use to treat inflammatory conditions |
| US6008255A (en) * | 1994-01-21 | 1999-12-28 | The Picower Institute For Medical Research | Guanylhydrazones and their use to treat inflammatory conditions |
| JP3823330B2 (ja) * | 1994-11-09 | 2006-09-20 | 昭和電工株式会社 | N−ホスホノメチルグリシンの単離方法 |
| JP2001503775A (ja) | 1996-11-15 | 2001-03-21 | ザ ピコワー インスティテュート フォー メディカル リサーチ | T細胞の活性化に関係する疾患を治療するために有用なグアニルヒドラゾン |
| US6319894B1 (en) | 1997-01-08 | 2001-11-20 | The Picower Institute For Medical Research | Complexes and combinations of fetuin with therapeutic agents |
| ES2250363T3 (es) * | 2000-02-02 | 2006-04-16 | Dorian Bevec | Guanilhidrazonas aromaticas farmaceuticamente activas. |
| WO2002000613A2 (en) * | 2000-06-27 | 2002-01-03 | Axxima Pharmaceuticals Ag | Inhibitors of hepatitis b virus infection |
| WO2003006426A1 (en) * | 2001-07-13 | 2003-01-23 | Axxima Pharmaceuticals Ag | Aromatic guanylhydrazones as effective compounds against neurodiseases |
| EP1435932A4 (en) * | 2001-09-21 | 2006-12-06 | Message Pharmaceuticals Inc | INHIBITORS OF RNASE-P PROTEINS AS ANTIBACTERIAL COMPOUNDS |
| CA2476896A1 (en) * | 2002-02-26 | 2003-09-04 | North Shore-Long Island Jewish Research Institute | Inhibition of inflammatory cytokine production by stimulation of brain muscarinic receptors |
| EP1389480A1 (en) * | 2002-08-14 | 2004-02-18 | Mondobiotech Interferon SA | Therapeutical use of guanylhydrazones for the inhibition of CD83 dependent processes and dendritic cell maturation |
| US7244765B2 (en) * | 2004-06-25 | 2007-07-17 | Cytokine Pharmasciences, Inc | Guanylhydrazone salts, compositions, processes of making and methods of using |
| MX2007001928A (es) * | 2004-08-17 | 2007-04-17 | Cytokine Pharmasciences Inc | Metodos para producir y utilizar los compuestos o composiciones de guanilhidrazona. |
-
2005
- 2005-08-17 MX MX2007001928A patent/MX2007001928A/es active IP Right Grant
- 2005-08-17 US US11/205,187 patent/US7291647B2/en not_active Expired - Lifetime
- 2005-08-17 PL PL05785277T patent/PL1778265T3/pl unknown
- 2005-08-17 EP EP12179899.5A patent/EP2543661B1/en not_active Expired - Lifetime
- 2005-08-17 CA CA2577156A patent/CA2577156C/en not_active Expired - Lifetime
- 2005-08-17 CN CN2012103951620A patent/CN102936212A/zh active Pending
- 2005-08-17 CN CN2005800281235A patent/CN101010094B/zh not_active Expired - Lifetime
- 2005-08-17 BR BRPI0514452A patent/BRPI0514452A8/pt not_active Application Discontinuation
- 2005-08-17 JP JP2007527986A patent/JP5198863B2/ja not_active Expired - Lifetime
- 2005-08-17 WO PCT/US2005/029301 patent/WO2006023586A2/en not_active Ceased
- 2005-08-17 AU AU2005277456A patent/AU2005277456B2/en not_active Expired
- 2005-08-17 ES ES05785277T patent/ES2422425T3/es not_active Expired - Lifetime
- 2005-08-17 DK DK05785277.4T patent/DK1778265T3/da active
- 2005-08-17 EP EP05785277.4A patent/EP1778265B1/en not_active Expired - Lifetime
- 2005-08-17 PT PT57852774T patent/PT1778265E/pt unknown
-
2007
- 2007-09-17 US US11/856,226 patent/US7863334B2/en not_active Expired - Lifetime
-
2010
- 2010-12-07 US US12/961,657 patent/US8247455B2/en not_active Expired - Lifetime
-
2012
- 2012-11-28 JP JP2012259862A patent/JP5551755B2/ja not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| BRPI0514452A8 (pt) | 2018-02-06 |
| JP2008510703A (ja) | 2008-04-10 |
| CN101010094B (zh) | 2013-05-22 |
| PT1778265E (pt) | 2013-08-05 |
| CA2577156A1 (en) | 2006-03-02 |
| CA2577156C (en) | 2013-11-26 |
| JP5198863B2 (ja) | 2013-05-15 |
| EP1778265A2 (en) | 2007-05-02 |
| CN102936212A (zh) | 2013-02-20 |
| US20110144189A1 (en) | 2011-06-16 |
| BRPI0514452A (pt) | 2008-06-10 |
| WO2006023586A2 (en) | 2006-03-02 |
| CN101010094A (zh) | 2007-08-01 |
| WO2006023586A3 (en) | 2007-01-04 |
| US7863334B2 (en) | 2011-01-04 |
| US20060041002A1 (en) | 2006-02-23 |
| AU2005277456B2 (en) | 2011-12-01 |
| US7291647B2 (en) | 2007-11-06 |
| MX2007001928A (es) | 2007-04-17 |
| US20080070959A1 (en) | 2008-03-20 |
| ES2422425T3 (es) | 2013-09-11 |
| JP5551755B2 (ja) | 2014-07-16 |
| EP2543661B1 (en) | 2016-12-07 |
| JP2013100291A (ja) | 2013-05-23 |
| EP1778265A4 (en) | 2010-01-06 |
| AU2005277456A1 (en) | 2006-03-02 |
| DK1778265T3 (da) | 2013-06-24 |
| US8247455B2 (en) | 2012-08-21 |
| EP1778265B1 (en) | 2013-04-24 |
| EP2543661A1 (en) | 2013-01-09 |
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