PL1742947T3 - Wytwarzanie pochodnych pirydoindolowych podstawionych w pozycji-6 i ich zastosowanie terapeutyczne - Google Patents

Wytwarzanie pochodnych pirydoindolowych podstawionych w pozycji-6 i ich zastosowanie terapeutyczne

Info

Publication number
PL1742947T3
PL1742947T3 PL05759933T PL05759933T PL1742947T3 PL 1742947 T3 PL1742947 T3 PL 1742947T3 PL 05759933 T PL05759933 T PL 05759933T PL 05759933 T PL05759933 T PL 05759933T PL 1742947 T3 PL1742947 T3 PL 1742947T3
Authority
PL
Poland
Prior art keywords
therapeutic use
derivatives production
substituted
pyridoindolone derivatives
substituted pyridoindolone
Prior art date
Application number
PL05759933T
Other languages
English (en)
Inventor
Bernard Bourrie
Pierre Casellas
Paola Ciapetti
Jean Marie Derocq
Samir Jegham
Yvette Muneaux
Camille-George Wermuth
Original Assignee
Sanofi Aventis
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Aventis filed Critical Sanofi Aventis
Publication of PL1742947T3 publication Critical patent/PL1742947T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Indole Compounds (AREA)
PL05759933T 2004-04-21 2005-04-20 Wytwarzanie pochodnych pirydoindolowych podstawionych w pozycji-6 i ich zastosowanie terapeutyczne PL1742947T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR0404251A FR2869316B1 (fr) 2004-04-21 2004-04-21 Derives de pyridoindolone substitues en -6, leur preparation et leur application en therapeutique.
EP05759933A EP1742947B1 (fr) 2004-04-21 2005-04-20 Derives de pyridoindolone substitues en -6, leur preparation, leur application en therapeutique.
PCT/FR2005/000971 WO2005108398A1 (fr) 2004-04-21 2005-04-20 Derives de pyridoindolone substitues en -6, leur preparation, leur application en therapeutique.

Publications (1)

Publication Number Publication Date
PL1742947T3 true PL1742947T3 (pl) 2009-01-30

Family

ID=34945552

Family Applications (1)

Application Number Title Priority Date Filing Date
PL05759933T PL1742947T3 (pl) 2004-04-21 2005-04-20 Wytwarzanie pochodnych pirydoindolowych podstawionych w pozycji-6 i ich zastosowanie terapeutyczne

Country Status (31)

Country Link
US (1) US7812165B2 (pl)
EP (1) EP1742947B1 (pl)
JP (1) JP4809830B2 (pl)
KR (1) KR20070002094A (pl)
CN (1) CN100537568C (pl)
AR (1) AR048932A1 (pl)
AT (1) ATE405565T1 (pl)
AU (1) AU2005240816A1 (pl)
BR (1) BRPI0510060A (pl)
CA (1) CA2562561A1 (pl)
CR (1) CR8677A (pl)
DE (1) DE602005009166D1 (pl)
DK (1) DK1742947T3 (pl)
EC (1) ECSP066918A (pl)
ES (1) ES2313371T3 (pl)
FR (1) FR2869316B1 (pl)
HK (1) HK1106223A1 (pl)
IL (1) IL178444A0 (pl)
MA (1) MA28546B1 (pl)
MX (1) MXPA06012127A (pl)
MY (1) MY137599A (pl)
NO (1) NO20065323L (pl)
PL (1) PL1742947T3 (pl)
PT (1) PT1742947E (pl)
RU (1) RU2364595C2 (pl)
TN (1) TNSN06337A1 (pl)
TW (1) TW200538114A (pl)
UA (1) UA85709C2 (pl)
UY (1) UY28864A1 (pl)
WO (1) WO2005108398A1 (pl)
ZA (1) ZA200608646B (pl)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2823975B1 (fr) 2001-04-27 2003-05-30 Sanofi Synthelabo Nouvelle utilisation de pyridoindolone
US7456193B2 (en) 2002-10-23 2008-11-25 Sanofi-Aventis Pyridoindolone derivatives substituted in the 3-position by a heterocyclic group, their preparation and their application in therapeutics
FR2846329B1 (fr) 2002-10-23 2004-12-03 Sanofi Synthelabo Derives de pyridoindolone substitues en -3 par un phenyle, leur preparation et leur application en therapeutique
FR2892416B1 (fr) 2005-10-20 2008-06-27 Sanofi Aventis Sa Derives de 6-heteroarylpyridoindolone, leur preparation et leur application en therapeutique

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1268772A (en) 1968-03-15 1972-03-29 Glaxo Lab Ltd NOVEL alpha-CARBOLINE DERIVATIVES, THE PREPARATION THEREOF AND COMPOSITIONS CONTAINING THE SAME
US4263304A (en) * 1978-06-05 1981-04-21 Sumitomo Chemical Company, Limited 7 H-indolo[2,3-c]isoquinolines
SU833971A1 (ru) 1979-07-10 1981-05-30 Ленинградский Химико-Фармацевтическийинститут Способ получени 3-фенил-2-оксо- - КАРбОлиНОВ
FR2595701B1 (fr) * 1986-03-17 1988-07-01 Sanofi Sa Derives du pyrido-indole, leur application a titre de medicaments et les compositions les renfermant
ATE386131T1 (de) 1994-04-13 2008-03-15 Univ Rockefeller Aav-vermittelte überbringung von dna in zellen des nervensystems
DE19502753A1 (de) * 1995-01-23 1996-07-25 Schering Ag Neue 9H-Pyrido[3,4-b]indol-Derivate
FR2765582B1 (fr) 1997-07-03 1999-08-06 Synthelabo Derives de 3-alkyl-1,9-dihydro-2h-pyrido[2,3-b]indol-2-one leur preparation et leur application en therapeutique
FR2765581B1 (fr) * 1997-07-03 1999-08-06 Synthelabo Derives de 3-aryl-1,9-dihydro-2h-pyrido[2,3-b]indol-2-one, leur preparation et leur application en therapeutique
AU3375999A (en) 1998-04-02 1999-10-25 Neurogen Corporation Aminoalkyl substituted 5,6,7,8-tetrahydro-9h pyrimidino(2,3-b)indole and 5,6,7,8-tetrahydro-9h-pyrimidino(4,5-b)indole derivatives: crf1 specific ligands
IT1313592B1 (it) 1999-08-03 2002-09-09 Novuspharma Spa Derivati di 1h-pirido 3,4-b indol-1-one.
US20020156016A1 (en) 2001-03-30 2002-10-24 Gerald Minuk Control of cell growth by altering cell membrane potentials
FR2823975B1 (fr) * 2001-04-27 2003-05-30 Sanofi Synthelabo Nouvelle utilisation de pyridoindolone
US7456193B2 (en) * 2002-10-23 2008-11-25 Sanofi-Aventis Pyridoindolone derivatives substituted in the 3-position by a heterocyclic group, their preparation and their application in therapeutics
FR2846329B1 (fr) * 2002-10-23 2004-12-03 Sanofi Synthelabo Derives de pyridoindolone substitues en -3 par un phenyle, leur preparation et leur application en therapeutique
FR2846330B1 (fr) 2002-10-23 2004-12-03 Sanofi Synthelabo Derives de pyridoindolone substitues en -3 par groupe heterocyclique, leur preparation et leur application en therapeutique
FR2892416B1 (fr) * 2005-10-20 2008-06-27 Sanofi Aventis Sa Derives de 6-heteroarylpyridoindolone, leur preparation et leur application en therapeutique

Also Published As

Publication number Publication date
PT1742947E (pt) 2008-11-25
JP4809830B2 (ja) 2011-11-09
JP2007533710A (ja) 2007-11-22
TW200538114A (en) 2005-12-01
FR2869316B1 (fr) 2006-06-02
ECSP066918A (es) 2007-01-26
MA28546B1 (fr) 2007-04-03
WO2005108398A1 (fr) 2005-11-17
HK1106223A1 (en) 2008-03-07
KR20070002094A (ko) 2007-01-04
BRPI0510060A (pt) 2007-10-16
UY28864A1 (es) 2005-11-30
AR048932A1 (es) 2006-06-14
CN1956986A (zh) 2007-05-02
ZA200608646B (en) 2008-02-27
DK1742947T3 (da) 2009-01-05
EP1742947A1 (fr) 2007-01-17
US7812165B2 (en) 2010-10-12
DE602005009166D1 (de) 2008-10-02
CN100537568C (zh) 2009-09-09
ES2313371T3 (es) 2009-03-01
RU2006140998A (ru) 2008-05-27
CA2562561A1 (fr) 2005-11-17
EP1742947B1 (fr) 2008-08-20
MY137599A (en) 2009-02-27
TNSN06337A1 (en) 2008-02-22
RU2364595C2 (ru) 2009-08-20
IL178444A0 (en) 2007-02-11
FR2869316A1 (fr) 2005-10-28
MXPA06012127A (es) 2007-01-31
UA85709C2 (ru) 2009-02-25
AU2005240816A1 (en) 2005-11-17
CR8677A (es) 2007-08-28
ATE405565T1 (de) 2008-09-15
NO20065323L (no) 2006-12-08
US20070129365A1 (en) 2007-06-07

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