PL1732556T3 - Sposób wytwarzania 3-amino-8-(1-piperazynylo)-2H-1-benzopiran-2-onu oraz jego soli i hydratów - Google Patents
Sposób wytwarzania 3-amino-8-(1-piperazynylo)-2H-1-benzopiran-2-onu oraz jego soli i hydratówInfo
- Publication number
- PL1732556T3 PL1732556T3 PL05717126T PL05717126T PL1732556T3 PL 1732556 T3 PL1732556 T3 PL 1732556T3 PL 05717126 T PL05717126 T PL 05717126T PL 05717126 T PL05717126 T PL 05717126T PL 1732556 T3 PL1732556 T3 PL 1732556T3
- Authority
- PL
- Poland
- Prior art keywords
- benzopyran
- piperazinyl
- hydrates
- salts
- amino
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/06—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2
- C07D311/08—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring
- C07D311/18—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring substituted otherwise than in position 3 or 7
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurosurgery (AREA)
- Medicinal Chemistry (AREA)
- Neurology (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Psychology (AREA)
- Anesthesiology (AREA)
- Otolaryngology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Pyrane Compounds (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US55595804P | 2004-03-25 | 2004-03-25 | |
EP04101228 | 2004-03-25 | ||
EP05717126A EP1732556B1 (en) | 2004-03-25 | 2005-03-23 | Process for the preparation of 3-amino-8-(1-piperazinyl)-2h-1-benzopyran-2-one and salts and hydrates thereof |
PCT/EP2005/051326 WO2005092338A1 (en) | 2004-03-25 | 2005-03-23 | Process for the preparation of 3-amino-8-(1-piperazinyl) -2h-1-benzopyran-2-one and salts and hydrates thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
PL1732556T3 true PL1732556T3 (pl) | 2008-09-30 |
Family
ID=34928926
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PL05717126T PL1732556T3 (pl) | 2004-03-25 | 2005-03-23 | Sposób wytwarzania 3-amino-8-(1-piperazynylo)-2H-1-benzopiran-2-onu oraz jego soli i hydratów |
Country Status (12)
Country | Link |
---|---|
US (2) | US7776860B2 (pl) |
EP (1) | EP1732556B1 (pl) |
JP (1) | JP2007530507A (pl) |
AR (1) | AR049478A1 (pl) |
AT (1) | ATE388709T1 (pl) |
CA (1) | CA2554041A1 (pl) |
DE (1) | DE602005005308T2 (pl) |
ES (1) | ES2303674T3 (pl) |
PL (1) | PL1732556T3 (pl) |
SA (1) | SA05260061B1 (pl) |
TW (1) | TWI340136B (pl) |
WO (1) | WO2005092338A1 (pl) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AR048112A1 (es) * | 2004-03-25 | 2006-03-29 | Solvay Pharm Bv | Derivados de 1-(2h-1-benzopiran-2-on-8-il)-piperazina para el tratamiento de dolor |
JP6061373B2 (ja) * | 2012-07-24 | 2017-01-18 | 国立研究開発法人産業技術総合研究所 | 2−ヒドロキシベンズアルデヒド化合物、これを含有するコラーゲン細胞外分泌阻害剤及び医薬品組成物 |
WO2020183011A1 (en) | 2019-03-14 | 2020-09-17 | Institut Curie | Htr1d inhibitors and uses thereof in the treatment of cancer |
Family Cites Families (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3586794T2 (de) | 1984-12-21 | 1993-05-27 | Duphar Int Res | Arzneimittel mit psychotroper wirkung. |
DK611489A (da) | 1988-12-08 | 1990-06-09 | Duphar Int Res | Anxiolytisk aktive piperazinderivater og farmaceutiske praeparater med indhold af saadanne forbindelser |
US5009895A (en) * | 1990-02-02 | 1991-04-23 | Merck & Co., Inc. | Sustained release with high and low viscosity HPMC |
FR2670491B1 (fr) * | 1990-12-14 | 1993-02-05 | Adir | Nouvelles piperazines 1,4-disubstituees, leur procede de preparation et les compositions pharmaceutiques les renfermant. |
ATE204262T1 (de) | 1991-09-18 | 2001-09-15 | Glaxo Group Ltd | Benzanilidderivate als 5-ht1d-antagonisten |
AU3241093A (en) | 1992-01-07 | 1993-08-03 | Merrell Dow Pharmaceuticals Inc. | Treatment of involuntary movements with 5HT-1A receptor agonists |
EP0650964A1 (en) * | 1993-11-02 | 1995-05-03 | Duphar International Research B.V | 1 2H-1-benzopyran-2-one-8-yl -piperazine derivatives |
US5478572A (en) * | 1994-09-06 | 1995-12-26 | Bristol-Myers Squibb Co. | Gepirone dosage form |
NL9401572A (nl) | 1994-09-27 | 1996-05-01 | Avebe Coop Verkoop Prod | Zetmeelprodukten als tabletteerhulpstof, werkwijze voor het bereiden daarvan alsmede werkwijze voor het maken van tabletten. |
PL189256B1 (pl) | 1996-03-29 | 2005-07-29 | Duphar Int Res | Związki piperazyny i piperydyny, sposób ich wytwarzania, kompozycja farmaceutyczna zawierająca te związki, zastosowanie tych związków do wytwarzania leków |
GB9706089D0 (en) | 1997-03-24 | 1997-05-14 | Scherer Ltd R P | Pharmaceutical composition |
PA8469101A1 (es) | 1998-04-09 | 2000-09-29 | Pfizer Prod Inc | Ligandos azabiciclicos de receptores 5ht1 |
US6376494B1 (en) * | 1998-06-15 | 2002-04-23 | American Home Products Corporation | Cycloalkyl-substituted aryl-piperazines, piperidines and tetrahydropyridines as serotonergic agents |
US6312717B1 (en) * | 1998-07-07 | 2001-11-06 | Bristol-Myers Squibb Company | Method for treatment of anxiety and depression |
UA62015C2 (en) | 1998-12-28 | 2003-12-15 | Pfizer Prod Inc | Benzoizoxazol derivatives, a pharmaceutical composition (variants) based thereon (variants) and a method for treatment (variants) |
GB0008563D0 (en) * | 2000-04-07 | 2000-05-24 | Cambridge Discovery Chemistry | Investigating different physical and/or chemical forms of materials |
JP2004231514A (ja) | 2000-08-31 | 2004-08-19 | Meiji Seika Kaisha Ltd | 5−ht7受容体結合能を有し、かつ代謝的に安定なテトラヒドロベンズインドール誘導体 |
US20030008880A1 (en) * | 2001-05-02 | 2003-01-09 | Pfizer Inc. | 4-(2-Pyridyl) piperizines having 5HT7 receptor agonist activity |
US6696496B2 (en) * | 2002-03-28 | 2004-02-24 | Synthon Bv | Low water-soluble venlafaxine salts |
FR2837822B1 (fr) * | 2002-03-29 | 2004-06-04 | Bioprojet Soc Civ | Formes polymorphes du fasidotril, leurs procedes de preparation et compositions pharmaceutiques les contenant |
AR048112A1 (es) * | 2004-03-25 | 2006-03-29 | Solvay Pharm Bv | Derivados de 1-(2h-1-benzopiran-2-on-8-il)-piperazina para el tratamiento de dolor |
US20050215551A1 (en) * | 2004-03-25 | 2005-09-29 | Solvay Pharmaceuticals B.V. | 1-[2H-1-benzopyran-2-one-8-yl]- piperazine derivatives for the treatment of movement disorders |
-
2005
- 2005-03-21 AR ARP050101091A patent/AR049478A1/es not_active Application Discontinuation
- 2005-03-22 SA SA05260061A patent/SA05260061B1/ar unknown
- 2005-03-22 TW TW094108777A patent/TWI340136B/zh not_active IP Right Cessation
- 2005-03-22 US US11/085,136 patent/US7776860B2/en not_active Expired - Fee Related
- 2005-03-23 JP JP2007504416A patent/JP2007530507A/ja active Pending
- 2005-03-23 WO PCT/EP2005/051326 patent/WO2005092338A1/en active IP Right Grant
- 2005-03-23 CA CA002554041A patent/CA2554041A1/en not_active Abandoned
- 2005-03-23 PL PL05717126T patent/PL1732556T3/pl unknown
- 2005-03-23 AT AT05717126T patent/ATE388709T1/de not_active IP Right Cessation
- 2005-03-23 ES ES05717126T patent/ES2303674T3/es active Active
- 2005-03-23 EP EP05717126A patent/EP1732556B1/en not_active Not-in-force
- 2005-03-23 DE DE602005005308T patent/DE602005005308T2/de active Active
-
2010
- 2010-07-02 US US12/829,554 patent/US8173660B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
EP1732556A1 (en) | 2006-12-20 |
ES2303674T3 (es) | 2008-08-16 |
CA2554041A1 (en) | 2005-10-06 |
AR049478A1 (es) | 2006-08-09 |
TWI340136B (en) | 2011-04-11 |
DE602005005308D1 (de) | 2008-04-24 |
US7776860B2 (en) | 2010-08-17 |
TW200611900A (en) | 2006-04-16 |
US20110003830A1 (en) | 2011-01-06 |
JP2007530507A (ja) | 2007-11-01 |
US8173660B2 (en) | 2012-05-08 |
DE602005005308T2 (de) | 2009-10-08 |
EP1732556B1 (en) | 2008-03-12 |
WO2005092338A1 (en) | 2005-10-06 |
ATE388709T1 (de) | 2008-03-15 |
US20050215566A1 (en) | 2005-09-29 |
SA05260061B1 (ar) | 2009-01-19 |
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