PL1668152T3 - Identyfikacja sygnatury ekspresji genów ERBB2 w rakach sutka - Google Patents
Identyfikacja sygnatury ekspresji genów ERBB2 w rakach sutkaInfo
- Publication number
- PL1668152T3 PL1668152T3 PL04769358T PL04769358T PL1668152T3 PL 1668152 T3 PL1668152 T3 PL 1668152T3 PL 04769358 T PL04769358 T PL 04769358T PL 04769358 T PL04769358 T PL 04769358T PL 1668152 T3 PL1668152 T3 PL 1668152T3
- Authority
- PL
- Poland
- Prior art keywords
- gene expression
- identification
- breast cancer
- expression signature
- erbb2 gene
- Prior art date
Links
- 206010006187 Breast cancer Diseases 0.000 title abstract 2
- 208000026310 Breast neoplasm Diseases 0.000 title abstract 2
- 108700020302 erbB-2 Genes Proteins 0.000 title 1
- 230000014509 gene expression Effects 0.000 title 1
- 102000040430 polynucleotide Human genes 0.000 abstract 3
- 108091033319 polynucleotide Proteins 0.000 abstract 3
- 239000002157 polynucleotide Substances 0.000 abstract 3
- 230000002018 overexpression Effects 0.000 abstract 2
- 239000012472 biological sample Substances 0.000 abstract 1
- 230000000295 complement effect Effects 0.000 abstract 1
- 238000001514 detection method Methods 0.000 abstract 1
- 230000009274 differential gene expression Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 230000009452 underexpressoin Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
- C12Q1/6837—Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/112—Disease subtyping, staging or classification
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Analytical Chemistry (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Hospice & Palliative Care (AREA)
- Biophysics (AREA)
- Oncology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US49849703P | 2003-08-28 | 2003-08-28 | |
| US10/928,465 US20050089899A1 (en) | 2003-08-28 | 2004-08-27 | Identification of an ERBB2 gene expression signature in breast cancers |
| EP04769358A EP1668152B1 (en) | 2003-08-28 | 2004-08-27 | Identification of an erbb2 gene expression signature in breast cancer |
| PCT/IB2004/002968 WO2005021788A1 (en) | 2003-08-28 | 2004-08-27 | Identification of an erbb2 gene expression signature in breast cancer |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL1668152T3 true PL1668152T3 (pl) | 2009-06-30 |
Family
ID=34278600
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL04769358T PL1668152T3 (pl) | 2003-08-28 | 2004-08-27 | Identyfikacja sygnatury ekspresji genów ERBB2 w rakach sutka |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US20050089899A1 (pl) |
| EP (2) | EP1980629A3 (pl) |
| AT (1) | ATE403755T1 (pl) |
| DE (1) | DE602004015626D1 (pl) |
| ES (1) | ES2311852T3 (pl) |
| PL (1) | PL1668152T3 (pl) |
| WO (1) | WO2005021788A1 (pl) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2007530075A (ja) * | 2004-04-23 | 2007-11-01 | エグザジェン ダイアグノスティクス インコーポレイテッド | 乳がんの予後診断のための組成物および方法 |
| EP1907410B1 (en) | 2005-06-10 | 2012-07-04 | Saint Louis University | Methods for the selection of aptamers |
| ATE476529T1 (de) * | 2005-07-08 | 2010-08-15 | Siemens Healthcare Diagnostics | Verfahren zur vorhersage und überwachung einer unmittelbaren reaktion auf eine krebstherapie |
| CN103217520A (zh) * | 2006-02-27 | 2013-07-24 | 靶向分子诊断有限责任公司 | 用于减少细胞脂肪和预测用酪氨酸激酶抑制剂治疗后的心脏毒性的组合物和方法 |
| US12366585B2 (en) | 2006-05-18 | 2025-07-22 | Caris Mpi, Inc. | Molecular profiling of tumors |
| CN103424541B (zh) * | 2006-05-18 | 2018-01-30 | 分子压型学会股份有限公司 | 确定针对病状的个性化医疗介入的系统和方法 |
| US8768629B2 (en) | 2009-02-11 | 2014-07-01 | Caris Mpi, Inc. | Molecular profiling of tumors |
| WO2007140958A2 (en) * | 2006-06-02 | 2007-12-13 | Glaxosmithkline Biologicals S.A. | Method for identifying whether a patient will be responder or not to immunotherapy |
| WO2009049966A2 (en) * | 2007-09-07 | 2009-04-23 | Universite Libre De Bruxelles | Methods and tools for prognosis of cancer in her2+ patients |
| WO2009103790A2 (en) | 2008-02-21 | 2009-08-27 | Universite Libre De Bruxelles | Method and kit for the detection of genes associated with pik3ca mutation and involved in pi3k/akt pathway activation in the er-positive and her2-positive subtypes with clinical implications |
| WO2009114534A1 (en) * | 2008-03-14 | 2009-09-17 | The Regents Of The University Of California | Multi-gene classifiers and prognostic indicators for cancers |
| WO2010045318A2 (en) * | 2008-10-14 | 2010-04-22 | Caris Mpi, Inc. | Gene and gene expressed protein targets depicting biomarker patterns and signature sets by tumor type |
| US20100267803A1 (en) * | 2008-11-07 | 2010-10-21 | The Research Foundation Of State University Of New York | Regulators Of Fat Metabolism As Anti-Cancer Targets |
| WO2010056337A2 (en) | 2008-11-12 | 2010-05-20 | Caris Mpi, Inc. | Methods and systems of using exosomes for determining phenotypes |
| EP2373809A1 (en) * | 2008-12-10 | 2011-10-12 | Ipsogen | Methods for identifying erbb2 alteration in tumors |
| EP2253715A1 (en) * | 2009-05-14 | 2010-11-24 | RWTH Aachen | New targets for cancer therapy and/or diagnosis |
| GB0917457D0 (en) * | 2009-10-06 | 2009-11-18 | Glaxosmithkline Biolog Sa | Method |
| WO2011100561A1 (en) | 2010-02-12 | 2011-08-18 | Saint Louis University | Molecular biosensors capable of signal amplification |
| EP2542696B1 (en) | 2010-03-01 | 2016-09-28 | Caris Life Sciences Switzerland Holdings GmbH | Biomarkers for theranostics |
| JP2013526852A (ja) | 2010-04-06 | 2013-06-27 | カリス ライフ サイエンシズ ルクセンブルク ホールディングス | 疾患に対する循環バイオマーカー |
| WO2012149014A1 (en) | 2011-04-25 | 2012-11-01 | OSI Pharmaceuticals, LLC | Use of emt gene signatures in cancer drug discovery, diagnostics, and treatment |
| US10633710B2 (en) | 2014-08-15 | 2020-04-28 | Arizona Board Of Regents On Behalf Of The University Of Arizona | Methods for characterizing cancer |
| WO2016040830A1 (en) | 2014-09-12 | 2016-03-17 | Mediomics, Llc | Molecular biosensors with a modular design |
| JP6793451B2 (ja) * | 2014-11-14 | 2020-12-02 | キヤノンメディカルシステムズ株式会社 | 被検細胞の細胞特性を評価するための遺伝子マーカー、方法、レポーターベクター、プライマーセットおよびアッセイキット、並びに細胞特性評価装置 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2002010436A2 (en) * | 2000-07-28 | 2002-02-07 | The Brigham And Women's Hospital, Inc. | Prognostic classification of breast cancer |
| US20030096237A1 (en) * | 2000-08-28 | 2003-05-22 | Ulrich Certa | Determination of the ability of patients to respond to a tumor treatment |
| AU2002255478A1 (en) * | 2001-01-10 | 2002-09-12 | Pe Corporation (Ny) | Kits, such as nucleic acid arrays, comprising a majority of human exons or transcripts, for detecting expression and other uses thereof |
| WO2002059271A2 (en) * | 2001-01-25 | 2002-08-01 | Gene Logic, Inc. | Gene expression profiles in breast tissue |
| EP1410011B1 (en) * | 2001-06-18 | 2011-03-23 | Rosetta Inpharmatics LLC | Diagnosis and prognosis of breast cancer patients |
| US20030099974A1 (en) * | 2001-07-18 | 2003-05-29 | Millennium Pharmaceuticals, Inc. | Novel genes, compositions, kits and methods for identification, assessment, prevention, and therapy of breast cancer |
| US20030198972A1 (en) * | 2001-12-21 | 2003-10-23 | Erlander Mark G. | Grading of breast cancer |
| US20030190689A1 (en) * | 2002-04-05 | 2003-10-09 | Cell Signaling Technology,Inc. | Molecular profiling of disease and therapeutic response using phospho-specific antibodies |
-
2004
- 2004-08-27 AT AT04769358T patent/ATE403755T1/de not_active IP Right Cessation
- 2004-08-27 ES ES04769358T patent/ES2311852T3/es not_active Expired - Lifetime
- 2004-08-27 DE DE602004015626T patent/DE602004015626D1/de not_active Expired - Lifetime
- 2004-08-27 US US10/928,465 patent/US20050089899A1/en not_active Abandoned
- 2004-08-27 PL PL04769358T patent/PL1668152T3/pl unknown
- 2004-08-27 EP EP08007447A patent/EP1980629A3/en not_active Withdrawn
- 2004-08-27 EP EP04769358A patent/EP1668152B1/en not_active Expired - Lifetime
- 2004-08-27 WO PCT/IB2004/002968 patent/WO2005021788A1/en not_active Ceased
-
2008
- 2008-09-17 US US12/212,282 patent/US20090092983A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP1668152B1 (en) | 2008-08-06 |
| EP1668152A1 (en) | 2006-06-14 |
| US20090092983A1 (en) | 2009-04-09 |
| WO2005021788A1 (en) | 2005-03-10 |
| ES2311852T3 (es) | 2009-02-16 |
| EP1980629A3 (en) | 2008-12-17 |
| ATE403755T1 (de) | 2008-08-15 |
| DE602004015626D1 (de) | 2008-09-18 |
| US20050089899A1 (en) | 2005-04-28 |
| EP1980629A2 (en) | 2008-10-15 |
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