PL1618111T3 - Sole klopidogrelu i sposób wytwarzania - Google Patents
Sole klopidogrelu i sposób wytwarzaniaInfo
- Publication number
- PL1618111T3 PL1618111T3 PL04770646T PL04770646T PL1618111T3 PL 1618111 T3 PL1618111 T3 PL 1618111T3 PL 04770646 T PL04770646 T PL 04770646T PL 04770646 T PL04770646 T PL 04770646T PL 1618111 T3 PL1618111 T3 PL 1618111T3
- Authority
- PL
- Poland
- Prior art keywords
- clopidogrel
- salts
- preparation
- Prior art date
Links
- 239000005552 B01AC04 - Clopidogrel Substances 0.000 title 1
- GKTWGGQPFAXNFI-HNNXBMFYSA-N clopidogrel Chemical class C1([C@H](N2CC=3C=CSC=3CC2)C(=O)OC)=CC=CC=C1Cl GKTWGGQPFAXNFI-HNNXBMFYSA-N 0.000 title 1
- 229960003009 clopidogrel Drugs 0.000 title 1
- 150000003839 salts Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Cardiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Heart & Thoracic Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN413MU2003 | 2003-04-25 | ||
| EP04770646.0A EP1618111B1 (en) | 2003-04-25 | 2004-04-22 | Salts of clopidogrel and process for preparation |
| PCT/IN2004/000112 WO2004106344A2 (en) | 2003-04-25 | 2004-04-22 | Salts of clopidogrel and process for preparation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL1618111T3 true PL1618111T3 (pl) | 2015-06-30 |
Family
ID=33485475
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL04770646T PL1618111T3 (pl) | 2003-04-25 | 2004-04-22 | Sole klopidogrelu i sposób wytwarzania |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US7732608B2 (pl) |
| EP (4) | EP1927595B1 (pl) |
| KR (1) | KR20060013376A (pl) |
| CY (1) | CY1116554T1 (pl) |
| DE (1) | DE04770646T1 (pl) |
| DK (1) | DK1618111T3 (pl) |
| ES (1) | ES2531088T3 (pl) |
| HR (1) | HRP20150056T1 (pl) |
| NO (1) | NO333586B1 (pl) |
| PL (1) | PL1618111T3 (pl) |
| PT (1) | PT1618111E (pl) |
| SI (1) | SI1618111T1 (pl) |
| WO (1) | WO2004106344A2 (pl) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10305984A1 (de) * | 2003-02-13 | 2004-09-02 | Helm Ag | Salze organischer Säuren mit Clopidogrel und deren Verwendung zur Herstellung phamazeutischer Formulierungen |
| EP1603920A1 (en) * | 2003-03-12 | 2005-12-14 | Cadila Healthcare Ltd. | Polymorph and amorphous form of (s)-(+)-clopidogrel bisulfate |
| EP1927595B1 (en) | 2003-04-25 | 2013-03-06 | Cadila Healthcare Limited | Salts of clopidogrel and process for preparation |
| DK1680430T3 (da) * | 2003-11-03 | 2010-05-25 | Cadila Healthcare Ltd | Fremgangsmåder til fremstilling af form I af (S)-(+)-Clopidogrel-bisulfat |
| CN1922188A (zh) * | 2004-02-24 | 2007-02-28 | 齐格弗里德通用国际股份公司 | 氯吡格雷之药学可接受的盐 |
| WO2005103059A1 (en) * | 2004-04-20 | 2005-11-03 | Sanofi-Aventis | Clopidogrel salt and polymorphic forms thereof |
| WO2006074066A1 (en) * | 2004-12-30 | 2006-07-13 | Nektar Therapeutics | Non-crystalline formulation comprising clopidogrel |
| EP1934229B1 (en) | 2005-09-05 | 2012-09-26 | Cadila Healthcare Limited | Processes for the preparation of different forms of (s)-(+)-clopidogrel besylate |
| DE602007012497D1 (de) * | 2006-09-25 | 2011-03-31 | Adamed Sp Zoo | Neues Clopidogrel-Salz und seine kristallinen Formen |
| KR101378596B1 (ko) | 2006-12-27 | 2014-03-26 | 경동제약 주식회사 | 결정성 클로피도그렐 · 황산염 형태 ｉ의 제조방법 |
| US7935697B2 (en) | 2006-12-28 | 2011-05-03 | Kinex Pharmaceuticals, Llc | Compositions for modulating a kinase cascade and methods of use thereof |
| KR100805675B1 (ko) | 2007-03-07 | 2008-02-21 | 한림제약(주) | 클로피도그렐 베실레이트를 포함하는 약학 조성물 및 그의제조방법 |
| EP2062909A1 (en) * | 2007-11-21 | 2009-05-27 | SOLVAY (Société Anonyme) | Peptide production and purification process |
| KR100920932B1 (ko) * | 2007-12-05 | 2009-10-20 | 한림제약(주) | 결정형의 클로피도그렐 벤젠술폰산염의 제조방법 |
| EP2107061A1 (en) | 2008-04-02 | 2009-10-07 | Krka Tovarna Zdravil, D.D., Novo Mesto | Process for the preparation of optically enriched clopidogrel |
| WO2012123958A1 (en) | 2011-02-14 | 2012-09-20 | Cadila Healthcare Limited | Highly pure salts of clopidogrel free of genotoxic impurities |
| CN102199161B (zh) * | 2011-03-30 | 2013-07-03 | 天津红日药业股份有限公司 | 一种苯磺酸氯吡格雷晶型ⅰ及其制备方法和用途 |
| CN102285996A (zh) * | 2011-03-30 | 2011-12-21 | 天津红日药业股份有限公司 | 一种苯磺酸氯吡格雷晶型ⅱ及其制备方法和用途 |
| CN104193762B (zh) * | 2014-08-04 | 2017-02-15 | 浙江车头制药股份有限公司 | 一种制备苯磺酸氯吡格雷晶型ⅲ的方法 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2530247B1 (fr) | 1982-07-13 | 1986-05-16 | Sanofi Sa | Nouveaux derives de la thieno (3, 2-c) pyridine, leur procede de preparation et leur application therapeutique |
| GB8608335D0 (en) | 1986-04-04 | 1986-05-08 | Pfizer Ltd | Pharmaceutically acceptable salts |
| FR2623810B2 (fr) | 1987-02-17 | 1992-01-24 | Sanofi Sa | Sels de l'alpha-(tetrahydro-4,5,6,7 thieno(3,2-c) pyridyl-5) (chloro-2 phenyl) -acetate de methyle dextrogyre et compositions pharmaceutiques en contenant |
| FR2779726B1 (fr) * | 1998-06-15 | 2001-05-18 | Sanofi Sa | Forme polymorphe de l'hydrogenosulfate de clopidogrel |
| US6509348B1 (en) | 1998-11-03 | 2003-01-21 | Bristol-Myers Squibb Company | Combination of an ADP-receptor blocking antiplatelet drug and a thromboxane A2 receptor antagonist and a method for inhibiting thrombus formation employing such combination |
| DE19857137A1 (de) | 1998-12-11 | 2000-06-15 | Bayer Ag | Integriertes Verfahren zur Herstellung von Epoxiden aus Olefinen |
| IN191030B (pl) | 2001-01-24 | 2003-09-13 | Cadila Healthcare Ltd | |
| US6767913B2 (en) | 2001-12-18 | 2004-07-27 | Teva Pharmaceutical Industries Ltd. | Crystal forms iii, iv, v, and novel amorphous form of clopidogrel hydrogensulfate, processes for their preparation, processes for the preparation of form i, compositions containing the new forms and methods of administering the new forms |
| IL166593A0 (en) | 2002-08-02 | 2006-01-15 | Racemization and enantiomer separation of clopidogrel | |
| EP1606231A1 (en) | 2003-02-03 | 2005-12-21 | Nadkarni, Sunil Sadanand | Process for preparation of clopidogrel, its salts and pharmaceutical compositions |
| DE10305984A1 (de) | 2003-02-13 | 2004-09-02 | Helm Ag | Salze organischer Säuren mit Clopidogrel und deren Verwendung zur Herstellung phamazeutischer Formulierungen |
| EP1603920A1 (en) | 2003-03-12 | 2005-12-14 | Cadila Healthcare Ltd. | Polymorph and amorphous form of (s)-(+)-clopidogrel bisulfate |
| EP1927595B1 (en) | 2003-04-25 | 2013-03-06 | Cadila Healthcare Limited | Salts of clopidogrel and process for preparation |
| DK1680430T3 (da) | 2003-11-03 | 2010-05-25 | Cadila Healthcare Ltd | Fremgangsmåder til fremstilling af form I af (S)-(+)-Clopidogrel-bisulfat |
| EP1900358A1 (en) | 2006-09-16 | 2008-03-19 | Cimex Pharma AG | Pharmaceutical formulations comprising clopidogrel |
-
2004
- 2004-04-22 EP EP08001523A patent/EP1927595B1/en not_active Expired - Lifetime
- 2004-04-22 DE DE4770646T patent/DE04770646T1/de active Pending
- 2004-04-22 KR KR1020057020142A patent/KR20060013376A/ko not_active Ceased
- 2004-04-22 ES ES04770646T patent/ES2531088T3/es not_active Expired - Lifetime
- 2004-04-22 HR HRP20150056TT patent/HRP20150056T1/hr unknown
- 2004-04-22 PL PL04770646T patent/PL1618111T3/pl unknown
- 2004-04-22 SI SI200432209T patent/SI1618111T1/sl unknown
- 2004-04-22 US US10/554,367 patent/US7732608B2/en not_active Expired - Fee Related
- 2004-04-22 EP EP04770646.0A patent/EP1618111B1/en not_active Expired - Lifetime
- 2004-04-22 EP EP09010218A patent/EP2113506A3/en not_active Withdrawn
- 2004-04-22 WO PCT/IN2004/000112 patent/WO2004106344A2/en not_active Ceased
- 2004-04-22 PT PT47706460T patent/PT1618111E/pt unknown
- 2004-04-22 EP EP14192561.0A patent/EP2865681A3/en not_active Withdrawn
- 2004-04-22 DK DK04770646.0T patent/DK1618111T3/en active
-
2005
- 2005-10-17 NO NO20054763A patent/NO333586B1/no not_active IP Right Cessation
-
2010
- 2010-04-14 US US12/760,523 patent/US8053579B2/en not_active Expired - Fee Related
-
2015
- 2015-02-17 CY CY20151100161T patent/CY1116554T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP2113506A2 (en) | 2009-11-04 |
| PT1618111E (pt) | 2015-02-05 |
| KR20060013376A (ko) | 2006-02-09 |
| EP1927595B1 (en) | 2013-03-06 |
| SI1618111T1 (sl) | 2015-05-29 |
| EP1618111A2 (en) | 2006-01-25 |
| EP1927595A3 (en) | 2008-09-24 |
| WO2004106344A3 (en) | 2005-03-24 |
| HRP20150056T1 (hr) | 2015-04-24 |
| US7732608B2 (en) | 2010-06-08 |
| EP1927595A2 (en) | 2008-06-04 |
| DE04770646T1 (de) | 2011-12-08 |
| EP2865681A2 (en) | 2015-04-29 |
| NO333586B1 (no) | 2013-07-15 |
| WO2004106344A2 (en) | 2004-12-09 |
| EP1618111B1 (en) | 2014-12-24 |
| CY1116554T1 (el) | 2017-03-15 |
| US20100197923A1 (en) | 2010-08-05 |
| US8053579B2 (en) | 2011-11-08 |
| EP2113506A3 (en) | 2010-02-24 |
| ES2531088T3 (es) | 2015-03-10 |
| NO20054763L (no) | 2006-01-16 |
| EP2865681A3 (en) | 2015-08-19 |
| DK1618111T3 (en) | 2015-02-16 |
| US20060264636A1 (en) | 2006-11-23 |
| NO20054763D0 (no) | 2005-10-17 |
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