PH30969A - New N,N,N',N' tetrasubstituted-1,2-ethanediamine compounds. - Google Patents

New N,N,N',N' tetrasubstituted-1,2-ethanediamine compounds.

Info

Publication number
PH30969A
PH30969A PH48288A PH48288A PH30969A PH 30969 A PH30969 A PH 30969A PH 48288 A PH48288 A PH 48288A PH 48288 A PH48288 A PH 48288A PH 30969 A PH30969 A PH 30969A
Authority
PH
Philippines
Prior art keywords
pct
compounds
new
methylen
fluorophenyl
Prior art date
Application number
PH48288A
Other languages
English (en)
Inventor
Foguet Rafael
Gubert Santiago
Jose A Ortiz
Sacristan Aurelio
Josep M Castello
Original Assignee
Ferrer Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ferrer Int filed Critical Ferrer Int
Publication of PH30969A publication Critical patent/PH30969A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32One oxygen, sulfur or nitrogen atom
    • C07D239/42One nitrogen atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C211/00Compounds containing amino groups bound to a carbon skeleton
    • C07C211/01Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms
    • C07C211/26Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring
    • C07C211/29Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring the carbon skeleton being further substituted by halogen atoms or by nitro or nitroso groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/02Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C215/22Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated
    • C07C215/28Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings
    • C07C215/30Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings containing hydroxy groups and carbon atoms of six-membered aromatic rings bound to the same carbon atom of the carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C225/00Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones
    • C07C225/02Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones having amino groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C225/04Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones having amino groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being saturated
    • C07C225/06Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones having amino groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being saturated and acyclic

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Psychiatry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
PH48288A 1993-07-19 1994-05-16 New N,N,N',N' tetrasubstituted-1,2-ethanediamine compounds. PH30969A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES09301616A ES2074946B1 (es) 1993-07-19 1993-07-19 Nuevos compuestos derivados de la 1,2-etanodiamina-n,n,n',n'-tetrasustituida.

Publications (1)

Publication Number Publication Date
PH30969A true PH30969A (en) 1997-12-23

Family

ID=8282595

Family Applications (1)

Application Number Title Priority Date Filing Date
PH48288A PH30969A (en) 1993-07-19 1994-05-16 New N,N,N',N' tetrasubstituted-1,2-ethanediamine compounds.

Country Status (19)

Country Link
US (1) US5561135A (fi)
EP (1) EP0660819B1 (fi)
JP (1) JPH08503962A (fi)
KR (1) KR950703515A (fi)
AT (1) ATE159511T1 (fi)
AU (1) AU670716B2 (fi)
CA (1) CA2144758A1 (fi)
DE (1) DE69406406T2 (fi)
DK (1) DK0660819T3 (fi)
ES (1) ES2074946B1 (fi)
FI (1) FI951277A0 (fi)
GR (1) GR3025941T3 (fi)
MX (1) MX9403011A (fi)
NO (1) NO950974L (fi)
NZ (1) NZ271076A (fi)
PH (1) PH30969A (fi)
TW (1) TW262460B (fi)
WO (1) WO1995003270A1 (fi)
ZA (1) ZA943035B (fi)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1940389A2 (en) 2005-10-21 2008-07-09 Braincells, Inc. Modulation of neurogenesis by pde inhibition
US20070112017A1 (en) 2005-10-31 2007-05-17 Braincells, Inc. Gaba receptor mediated modulation of neurogenesis
US20100216734A1 (en) 2006-03-08 2010-08-26 Braincells, Inc. Modulation of neurogenesis by nootropic agents
MX2008014320A (es) 2006-05-09 2009-03-25 Braincells Inc Neurogenesis mediada por el receptor de 5-hidroxitriptamina.
AU2007249399A1 (en) 2006-05-09 2007-11-22 Braincells, Inc. Neurogenesis by modulating angiotensin
JP2010502722A (ja) 2006-09-08 2010-01-28 ブレインセルス,インコーポレイティド 4−アシルアミノピリジン誘導体を含む組み合わせ
US20100184806A1 (en) 2006-09-19 2010-07-22 Braincells, Inc. Modulation of neurogenesis by ppar agents
WO2010099217A1 (en) 2009-02-25 2010-09-02 Braincells, Inc. Modulation of neurogenesis using d-cycloserine combinations

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE757408A (fr) * 1969-10-13 1971-04-13 Thomae Gmbh Dr K Nouveaux butanols tertiaires a constituants basiques
FR2279383A1 (fr) * 1974-04-25 1976-02-20 Synthelabo Nouveaux derives tetrasubstitues des alcoylene-diamines, leurs sels, leur preparation et les medicaments qui en contiennent
US4605655A (en) * 1984-03-06 1986-08-12 Bristol-Myers Company Antipsychotic 1-fluorophenylbutyl-4-(2-pyrimidinyl)piperazine derivatives
US4588728A (en) * 1985-03-27 1986-05-13 Burroughs Wellcome Co. Treatment of drug induced psychosis
US4709094A (en) * 1986-07-10 1987-11-24 State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education, Acting For And On Behalf Of The Oregon Health Sciences University And The University Of Oregon Sigma brain receptor ligands and their use
US4929734A (en) * 1987-03-31 1990-05-29 Warner-Lambert Company Tetrahydropyridine oxime compounds
IT1205124B (it) * 1987-06-05 1989-03-15 Simens Soteta Italiana Medicin Composto attivo nella terapia carciovascolare
US4981870A (en) * 1989-03-07 1991-01-01 Pfizer Inc. Use of 4-phenyl-1,2,3,4-tetrahydro-1-naphthalenamine derivatives in the treatment of psychosis, inflammation and as immunosuppressants
US5109002A (en) * 1989-09-08 1992-04-28 Du Pont Merck Pharmaceutical Company Antipsychotic 1-cycloalkylpiperidines
US5149817A (en) * 1990-03-05 1992-09-22 Shionogi & Co., Ltd. Teirahydropyridine derivatives
US5116995A (en) * 1990-05-25 1992-05-26 Taisho Pharmaceutical Co., Ltd. Carbazole compounds
JP2935541B2 (ja) * 1990-06-28 1999-08-16 サントリー株式会社 縮合複素環化合物
US5086054A (en) * 1990-07-31 1992-02-04 Sri International Novel arylcycloalkanepolyalkylamines
DE4032767A1 (de) * 1990-10-16 1992-04-30 Basf Ag Phenylpiperidinoylamine und diese enthaltende arzneimittel
ATE138061T1 (de) * 1990-12-19 1996-06-15 Kali Chemie Pharma Gmbh Alkylaminoalkylamin- und -äther- verbindungen sowie verfahren und zwischenprodukte zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
US5162341A (en) * 1991-02-22 1992-11-10 Du Pont Merck Pharmaceutical Company Use of sigma receptor antagonists for treatment of amphetamine abuse
FR2675799B1 (fr) * 1991-04-24 1993-12-24 Synthelabo Derives de 2-aminopyrimidine-4-carboxamide, leur preparation et leur application en therapeutique.

Also Published As

Publication number Publication date
EP0660819A1 (en) 1995-07-05
DK0660819T3 (da) 1998-01-12
AU7459094A (en) 1995-02-20
DE69406406D1 (de) 1997-11-27
ATE159511T1 (de) 1997-11-15
NO950974D0 (no) 1995-03-14
ES2074946B1 (es) 1996-06-16
ES2074946A1 (es) 1995-09-16
DE69406406T2 (de) 1998-05-20
MX9403011A (es) 1995-01-31
EP0660819B1 (en) 1997-10-22
GR3025941T3 (en) 1998-04-30
NO950974L (no) 1995-03-14
CA2144758A1 (en) 1995-02-02
WO1995003270A1 (en) 1995-02-02
KR950703515A (ko) 1995-09-20
US5561135A (en) 1996-10-01
JPH08503962A (ja) 1996-04-30
TW262460B (fi) 1995-11-11
NZ271076A (en) 1996-03-26
FI951277A (fi) 1995-03-17
FI951277A0 (fi) 1995-03-17
ZA943035B (en) 1995-05-02
AU670716B2 (en) 1996-07-25

Similar Documents

Publication Publication Date Title
LU91751I2 (fr) Asenapin et ses dérivés pharmaceutiquement acceptables (SYCREST®)
BG103740A (en) Phytostyrene composition for the prevention of the alzheimer's disease
PL313821A1 (en) Analogues of distamycin a as anticarcinogenic and antiviral agents
IL115357A (en) Stable compositions containing N-propargyl-1-aminoindan and polyhydric alcohols
CY2461B1 (en) Polymorphic compounds.
EP0938317A4 (en) COMPOSITIONS AND METHODS FOR REDUCING RESPIRATORY DEPRESSION
GR3030371T3 (en) Triazole compounds and their use as dopamine-d 3?-ligands
GB9418912D0 (en) Pharmaceutically active compounds
GB9424766D0 (en) Pharmaceutical composition
TW262460B (fi)
TW254945B (fi)
IL108288A0 (en) Pyrrolidine derivatives, their preparation and medicaments containing them
GB9012157D0 (en) Compounds for the treatment of age related memory impairment and other cognitive disorders
IL104049A0 (en) 7'-amino-naphthazarin antibiotic derivatives
UY23362A1 (es) Procedimiento para la preparacion de derivado de triciclo de la piridona
IL108841A0 (en) Benzopyrans
MXPA02007454A (es) Compuestos utiles para tratamiento o prevencion de una enfermedad mediada por el alfa-2b-adrenoceptor.
ES2190373A1 (es) Uso del acido 2-hidroxi- o 2-acetiloxi-4-trifluorometilbenzoico como agente para el tratamiento y prevencion del deterioro cognitivo ligero.
GR3021604T3 (en) Application of riluzole as a radiorestorer.
AU3347895A (en) Triphenylethylenes for the prevention and treatment of osteoporosis
MX9701528A (es) Derivados de 1, 1, 2,- trifenilbut-1-eno para tratar la enfermedad de alzheimer.