MXPA02007454A - Compuestos utiles para tratamiento o prevencion de una enfermedad mediada por el alfa-2b-adrenoceptor. - Google Patents

Compuestos utiles para tratamiento o prevencion de una enfermedad mediada por el alfa-2b-adrenoceptor.

Info

Publication number
MXPA02007454A
MXPA02007454A MXPA02007454A MXPA02007454A MXPA02007454A MX PA02007454 A MXPA02007454 A MX PA02007454A MX PA02007454 A MXPA02007454 A MX PA02007454A MX PA02007454 A MXPA02007454 A MX PA02007454A MX PA02007454 A MXPA02007454 A MX PA02007454A
Authority
MX
Mexico
Prior art keywords
adrenoceptor
alpha
prevention
treatment
disease mediated
Prior art date
Application number
MXPA02007454A
Other languages
English (en)
Inventor
Eeva-Liisa Savola
Original Assignee
Juvantia Pharma Ltd Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FI20000303A external-priority patent/FI20000303A0/fi
Application filed by Juvantia Pharma Ltd Oy filed Critical Juvantia Pharma Ltd Oy
Publication of MXPA02007454A publication Critical patent/MXPA02007454A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/63—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32—One oxygen, sulfur or nitrogen atom
    • C07D239/42—One nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/63—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide
    • A61K31/635—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide having a heterocyclic ring, e.g. sulfadiazine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Abstract

La presente invencion se refiere al uso de un antagonista alfa-2B-adrenoceptor selectivo para la fabricacion de una preparacion farmaceutica util para el tratamiento o prevencion de una enfermedad mediada por el alfa-2B-adrenoceptor en un mamifero. El antagonista es un compuesto seleccionado del grupo que consiste de los compuestos A, B, C y D descritos en el Esquema I o una sal farmaceuticamente aceptable del compuesto. La presente invencion tambien se refiere a un metodo para tratamiento o prevencion de una enfermedad mediada por el alfa-2B-adrenoceptor en un mamifero. El metodo comprende administrar al mamifero una cantidad efectiva del antagonista alfa-2B-adrenoceptor selectivo.
MXPA02007454A 2000-02-11 2001-02-07 Compuestos utiles para tratamiento o prevencion de una enfermedad mediada por el alfa-2b-adrenoceptor. MXPA02007454A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US18202100P 2000-02-11 2000-02-11
FI20000303A FI20000303A0 (fi) 2000-02-14 2000-02-14 Alfa-2B-adrenoseptorivälitteisen sairauden hoitoon tai ehkäisyyn käyttökelpoiset yhdisteet
PCT/FI2001/000105 WO2001058454A1 (en) 2000-02-11 2001-02-07 Compounds useful for the treatment or prevention of a disease mediated by the alpha-2b-adrenoceptor

Publications (1)

Publication Number Publication Date
MXPA02007454A true MXPA02007454A (es) 2004-08-23

Family

ID=26160944

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA02007454A MXPA02007454A (es) 2000-02-11 2001-02-07 Compuestos utiles para tratamiento o prevencion de una enfermedad mediada por el alfa-2b-adrenoceptor.

Country Status (22)

Country Link
EP (1) EP1253926A1 (es)
JP (1) JP2003522148A (es)
KR (1) KR20020080413A (es)
AU (1) AU780802B2 (es)
BR (1) BR0108221A (es)
CA (1) CA2399421A1 (es)
CZ (1) CZ20022884A3 (es)
EA (1) EA200200846A1 (es)
EE (1) EE200200435A (es)
GE (1) GEP20043356B (es)
HR (1) HRP20020746A2 (es)
HU (1) HUP0300032A3 (es)
IL (1) IL151017A0 (es)
IS (1) IS6476A (es)
MX (1) MXPA02007454A (es)
MY (1) MY133957A (es)
NO (1) NO20023773L (es)
NZ (1) NZ520500A (es)
PL (1) PL357872A1 (es)
SK (1) SK11472002A3 (es)
WO (1) WO2001058454A1 (es)
YU (1) YU59102A (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MXPA04000615A (es) * 2001-07-20 2004-04-20 Juvantia Pharma Ltd Oy Compuestos utiles para el tratamiento o la prevencion de enfermedades mediadas por alfa-2b-adrenoceptor.
FI116940B (fi) 2001-07-20 2006-04-13 Juvantia Pharma Ltd Oy Alfa-2B-adrenoseptorivälitteisen sairauden hoitoon tai ehkäisyyn käyttökelpoiset yhdisteet

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8416432D0 (en) * 1984-06-28 1984-08-01 Wyeth John & Brother Ltd Benzoquinolizines
RU2086544C1 (ru) * 1991-06-13 1997-08-10 Хоффманн-Ля Рош АГ Бензолсульфонамидные производные пиримидина или их соли, фармацевтическая композиция для лечения заболеваний, связанных с активностью эндотелина
US6150389A (en) * 1994-07-11 2000-11-21 Allergan Sales, Inc. Comformationally rigid bicyclic and adamantane derivatives useful as α2 -adrenergic blocking agents

Also Published As

Publication number Publication date
KR20020080413A (ko) 2002-10-23
HUP0300032A3 (en) 2006-01-30
PL357872A1 (en) 2004-07-26
NZ520500A (en) 2005-01-28
CZ20022884A3 (cs) 2003-02-12
YU59102A (sh) 2005-11-28
WO2001058454A1 (en) 2001-08-16
MY133957A (en) 2007-11-30
JP2003522148A (ja) 2003-07-22
AU3551001A (en) 2001-08-20
BR0108221A (pt) 2003-03-05
AU780802B2 (en) 2005-04-21
NO20023773D0 (no) 2002-08-09
EP1253926A1 (en) 2002-11-06
CA2399421A1 (en) 2001-08-16
HRP20020746A2 (en) 2004-12-31
EA200200846A1 (ru) 2002-12-26
IL151017A0 (en) 2003-02-12
IS6476A (is) 2002-07-19
NO20023773L (no) 2002-08-09
EE200200435A (et) 2003-12-15
GEP20043356B (en) 2004-04-13
SK11472002A3 (sk) 2003-02-04
HUP0300032A2 (en) 2003-05-28

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