DE69406406D1 - Derivate von n,n,n',n'-tetrasubstituierten 1,2-ethylendiamin-verbindungen - Google Patents
Derivate von n,n,n',n'-tetrasubstituierten 1,2-ethylendiamin-verbindungenInfo
- Publication number
- DE69406406D1 DE69406406D1 DE69406406T DE69406406T DE69406406D1 DE 69406406 D1 DE69406406 D1 DE 69406406D1 DE 69406406 T DE69406406 T DE 69406406T DE 69406406 T DE69406406 T DE 69406406T DE 69406406 D1 DE69406406 D1 DE 69406406D1
- Authority
- DE
- Germany
- Prior art keywords
- pct
- substituted
- tetra
- compounds
- derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/32—One oxygen, sulfur or nitrogen atom
- C07D239/42—One nitrogen atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C211/00—Compounds containing amino groups bound to a carbon skeleton
- C07C211/01—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms
- C07C211/26—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring
- C07C211/29—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring the carbon skeleton being further substituted by halogen atoms or by nitro or nitroso groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
- C07C215/02—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C215/22—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated
- C07C215/28—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings
- C07C215/30—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings containing hydroxy groups and carbon atoms of six-membered aromatic rings bound to the same carbon atom of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C225/00—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones
- C07C225/02—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones having amino groups bound to acyclic carbon atoms of the carbon skeleton
- C07C225/04—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones having amino groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being saturated
- C07C225/06—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones having amino groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being saturated and acyclic
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES09301616A ES2074946B1 (es) | 1993-07-19 | 1993-07-19 | Nuevos compuestos derivados de la 1,2-etanodiamina-n,n,n',n'-tetrasustituida. |
| PCT/EP1994/002363 WO1995003270A1 (en) | 1993-07-19 | 1994-07-18 | New n,n,n',n'-tetrasubstituted-1,2-ethanediamine derivative compounds |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69406406D1 true DE69406406D1 (de) | 1997-11-27 |
| DE69406406T2 DE69406406T2 (de) | 1998-05-20 |
Family
ID=8282595
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69406406T Expired - Fee Related DE69406406T2 (de) | 1993-07-19 | 1994-07-18 | Derivate von n,n,n',n'-tetrasubstituierten 1,2-ethylendiamin-verbindungen |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US5561135A (de) |
| EP (1) | EP0660819B1 (de) |
| JP (1) | JPH08503962A (de) |
| KR (1) | KR950703515A (de) |
| AT (1) | ATE159511T1 (de) |
| AU (1) | AU670716B2 (de) |
| CA (1) | CA2144758A1 (de) |
| DE (1) | DE69406406T2 (de) |
| DK (1) | DK0660819T3 (de) |
| ES (1) | ES2074946B1 (de) |
| FI (1) | FI951277A0 (de) |
| GR (1) | GR3025941T3 (de) |
| MX (1) | MX9403011A (de) |
| NO (1) | NO950974D0 (de) |
| NZ (1) | NZ271076A (de) |
| PH (1) | PH30969A (de) |
| TW (1) | TW262460B (de) |
| WO (1) | WO1995003270A1 (de) |
| ZA (1) | ZA943035B (de) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1940389A2 (de) | 2005-10-21 | 2008-07-09 | Braincells, Inc. | Modulation von neurogenese durch pde-hemmung |
| CA2625210A1 (en) | 2005-10-31 | 2007-05-10 | Braincells, Inc. | Gaba receptor mediated modulation of neurogenesis |
| US20100216734A1 (en) | 2006-03-08 | 2010-08-26 | Braincells, Inc. | Modulation of neurogenesis by nootropic agents |
| MX2008014320A (es) | 2006-05-09 | 2009-03-25 | Braincells Inc | Neurogenesis mediada por el receptor de 5-hidroxitriptamina. |
| AU2007249399A1 (en) | 2006-05-09 | 2007-11-22 | Braincells, Inc. | Neurogenesis by modulating angiotensin |
| MX2009002496A (es) | 2006-09-08 | 2009-07-10 | Braincells Inc | Combinaciones que contienen un derivado de 4-acilaminopiridina. |
| US20100184806A1 (en) | 2006-09-19 | 2010-07-22 | Braincells, Inc. | Modulation of neurogenesis by ppar agents |
| US20100216805A1 (en) | 2009-02-25 | 2010-08-26 | Braincells, Inc. | Modulation of neurogenesis using d-cycloserine combinations |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE757408A (fr) * | 1969-10-13 | 1971-04-13 | Thomae Gmbh Dr K | Nouveaux butanols tertiaires a constituants basiques |
| FR2279383A1 (fr) * | 1974-04-25 | 1976-02-20 | Synthelabo | Nouveaux derives tetrasubstitues des alcoylene-diamines, leurs sels, leur preparation et les medicaments qui en contiennent |
| US4605655A (en) * | 1984-03-06 | 1986-08-12 | Bristol-Myers Company | Antipsychotic 1-fluorophenylbutyl-4-(2-pyrimidinyl)piperazine derivatives |
| US4588728A (en) * | 1985-03-27 | 1986-05-13 | Burroughs Wellcome Co. | Treatment of drug induced psychosis |
| US4709094A (en) * | 1986-07-10 | 1987-11-24 | State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education, Acting For And On Behalf Of The Oregon Health Sciences University And The University Of Oregon | Sigma brain receptor ligands and their use |
| US4929734A (en) * | 1987-03-31 | 1990-05-29 | Warner-Lambert Company | Tetrahydropyridine oxime compounds |
| IT1205124B (it) * | 1987-06-05 | 1989-03-15 | Simens Soteta Italiana Medicin | Composto attivo nella terapia carciovascolare |
| US4981870A (en) * | 1989-03-07 | 1991-01-01 | Pfizer Inc. | Use of 4-phenyl-1,2,3,4-tetrahydro-1-naphthalenamine derivatives in the treatment of psychosis, inflammation and as immunosuppressants |
| US5109002A (en) * | 1989-09-08 | 1992-04-28 | Du Pont Merck Pharmaceutical Company | Antipsychotic 1-cycloalkylpiperidines |
| US5149817A (en) * | 1990-03-05 | 1992-09-22 | Shionogi & Co., Ltd. | Teirahydropyridine derivatives |
| US5116995A (en) * | 1990-05-25 | 1992-05-26 | Taisho Pharmaceutical Co., Ltd. | Carbazole compounds |
| JP2935541B2 (ja) * | 1990-06-28 | 1999-08-16 | サントリー株式会社 | 縮合複素環化合物 |
| US5086054A (en) * | 1990-07-31 | 1992-02-04 | Sri International | Novel arylcycloalkanepolyalkylamines |
| DE4032767A1 (de) * | 1990-10-16 | 1992-04-30 | Basf Ag | Phenylpiperidinoylamine und diese enthaltende arzneimittel |
| ATE138061T1 (de) * | 1990-12-19 | 1996-06-15 | Kali Chemie Pharma Gmbh | Alkylaminoalkylamin- und -äther- verbindungen sowie verfahren und zwischenprodukte zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
| US5162341A (en) * | 1991-02-22 | 1992-11-10 | Du Pont Merck Pharmaceutical Company | Use of sigma receptor antagonists for treatment of amphetamine abuse |
| FR2675799B1 (fr) * | 1991-04-24 | 1993-12-24 | Synthelabo | Derives de 2-aminopyrimidine-4-carboxamide, leur preparation et leur application en therapeutique. |
-
1993
- 1993-07-19 ES ES09301616A patent/ES2074946B1/es not_active Expired - Fee Related
-
1994
- 1994-04-22 TW TW083103577A patent/TW262460B/zh active
- 1994-04-26 MX MX9403011A patent/MX9403011A/es unknown
- 1994-05-03 ZA ZA943035A patent/ZA943035B/xx unknown
- 1994-05-16 PH PH48288A patent/PH30969A/en unknown
- 1994-07-18 AU AU74590/94A patent/AU670716B2/en not_active Ceased
- 1994-07-18 US US08/392,987 patent/US5561135A/en not_active Expired - Fee Related
- 1994-07-18 JP JP7504929A patent/JPH08503962A/ja active Pending
- 1994-07-18 EP EP94924260A patent/EP0660819B1/de not_active Expired - Lifetime
- 1994-07-18 DE DE69406406T patent/DE69406406T2/de not_active Expired - Fee Related
- 1994-07-18 NZ NZ271076A patent/NZ271076A/en unknown
- 1994-07-18 AT AT94924260T patent/ATE159511T1/de not_active IP Right Cessation
- 1994-07-18 CA CA002144758A patent/CA2144758A1/en not_active Abandoned
- 1994-07-18 WO PCT/EP1994/002363 patent/WO1995003270A1/en active IP Right Grant
- 1994-07-18 DK DK94924260.6T patent/DK0660819T3/da active
- 1994-07-18 KR KR1019950701049A patent/KR950703515A/ko not_active Application Discontinuation
-
1995
- 1995-03-14 NO NO950974A patent/NO950974D0/no unknown
- 1995-03-17 FI FI951277A patent/FI951277A0/fi not_active Application Discontinuation
-
1998
- 1998-01-16 GR GR980400111T patent/GR3025941T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ATE159511T1 (de) | 1997-11-15 |
| NO950974L (no) | 1995-03-14 |
| ES2074946B1 (es) | 1996-06-16 |
| MX9403011A (es) | 1995-01-31 |
| PH30969A (en) | 1997-12-23 |
| CA2144758A1 (en) | 1995-02-02 |
| DK0660819T3 (da) | 1998-01-12 |
| NZ271076A (en) | 1996-03-26 |
| WO1995003270A1 (en) | 1995-02-02 |
| JPH08503962A (ja) | 1996-04-30 |
| AU670716B2 (en) | 1996-07-25 |
| ZA943035B (en) | 1995-05-02 |
| ES2074946A1 (es) | 1995-09-16 |
| US5561135A (en) | 1996-10-01 |
| AU7459094A (en) | 1995-02-20 |
| FI951277A (fi) | 1995-03-17 |
| FI951277A0 (fi) | 1995-03-17 |
| EP0660819B1 (de) | 1997-10-22 |
| GR3025941T3 (en) | 1998-04-30 |
| TW262460B (de) | 1995-11-11 |
| KR950703515A (ko) | 1995-09-20 |
| NO950974D0 (no) | 1995-03-14 |
| EP0660819A1 (de) | 1995-07-05 |
| DE69406406T2 (de) | 1998-05-20 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8339 | Ceased/non-payment of the annual fee |