PH26781A - Novel pharmaceutical composition for topical application with systemic action - Google Patents
Novel pharmaceutical composition for topical application with systemic action Download PDFInfo
- Publication number
- PH26781A PH26781A PH35441A PH35441A PH26781A PH 26781 A PH26781 A PH 26781A PH 35441 A PH35441 A PH 35441A PH 35441 A PH35441 A PH 35441A PH 26781 A PH26781 A PH 26781A
- Authority
- PH
- Philippines
- Prior art keywords
- diclofenac
- pharmaceutical composition
- topical application
- transdermal therapeutic
- effective amount
- Prior art date
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- 239000012982 microporous membrane Substances 0.000 description 1
- 239000000178 monomer Substances 0.000 description 1
- 229940105132 myristate Drugs 0.000 description 1
- IJDNQMDRQITEOD-UHFFFAOYSA-N n-butane Chemical compound CCCC IJDNQMDRQITEOD-UHFFFAOYSA-N 0.000 description 1
- GOQYKNQRPGWPLP-UHFFFAOYSA-N n-heptadecyl alcohol Natural products CCCCCCCCCCCCCCCCCO GOQYKNQRPGWPLP-UHFFFAOYSA-N 0.000 description 1
- OFBQJSOFQDEBGM-UHFFFAOYSA-N n-pentane Natural products CCCCC OFBQJSOFQDEBGM-UHFFFAOYSA-N 0.000 description 1
- QIQXTHQIDYTFRH-UHFFFAOYSA-N octadecanoic acid Chemical compound CCCCCCCCCCCCCCCCCC(O)=O QIQXTHQIDYTFRH-UHFFFAOYSA-N 0.000 description 1
- OQCDKBAXFALNLD-UHFFFAOYSA-N octadecanoic acid Natural products CCCCCCCC(C)CCCCCCCCC(O)=O OQCDKBAXFALNLD-UHFFFAOYSA-N 0.000 description 1
- CXQXSVUQTKDNFP-UHFFFAOYSA-N octamethyltrisiloxane Chemical compound C[Si](C)(C)O[Si](C)(C)O[Si](C)(C)C CXQXSVUQTKDNFP-UHFFFAOYSA-N 0.000 description 1
- 229940049964 oleate Drugs 0.000 description 1
- ZQPPMHVWECSIRJ-KTKRTIGZSA-N oleic acid Chemical compound CCCCCCCC\C=C/CCCCCCCC(O)=O ZQPPMHVWECSIRJ-KTKRTIGZSA-N 0.000 description 1
- 239000006072 paste Substances 0.000 description 1
- 239000000312 peanut oil Substances 0.000 description 1
- 229940049953 phenylacetate Drugs 0.000 description 1
- WLJVXDMOQOGPHL-UHFFFAOYSA-N phenylacetic acid Chemical compound OC(=O)CC1=CC=CC=C1 WLJVXDMOQOGPHL-UHFFFAOYSA-N 0.000 description 1
- 239000011505 plaster Substances 0.000 description 1
- 229920000435 poly(dimethylsiloxane) Polymers 0.000 description 1
- 229920000058 polyacrylate Polymers 0.000 description 1
- 229920001748 polybutylene Polymers 0.000 description 1
- 229920000223 polyglycerol Polymers 0.000 description 1
- 229920000193 polymethacrylate Polymers 0.000 description 1
- 229920001282 polysaccharide Polymers 0.000 description 1
- 239000005017 polysaccharide Substances 0.000 description 1
- 150000004804 polysaccharides Chemical class 0.000 description 1
- 229920000915 polyvinyl chloride Polymers 0.000 description 1
- 239000004800 polyvinyl chloride Substances 0.000 description 1
- 229920000036 polyvinylpyrrolidone Polymers 0.000 description 1
- 235000013855 polyvinylpyrrolidone Nutrition 0.000 description 1
- XAEFZNCEHLXOMS-UHFFFAOYSA-M potassium benzoate Chemical compound [K+].[O-]C(=O)C1=CC=CC=C1 XAEFZNCEHLXOMS-UHFFFAOYSA-M 0.000 description 1
- 230000002035 prolonged effect Effects 0.000 description 1
- 239000001294 propane Substances 0.000 description 1
- 125000001453 quaternary ammonium group Chemical group 0.000 description 1
- 150000003248 quinolines Chemical class 0.000 description 1
- 229920006395 saturated elastomer Polymers 0.000 description 1
- 229920002545 silicone oil Polymers 0.000 description 1
- 235000019333 sodium laurylsulphate Nutrition 0.000 description 1
- VCLVUNFJTOOMIR-UHFFFAOYSA-M sodium;acetyl sulfate Chemical compound [Na+].CC(=O)OS([O-])(=O)=O VCLVUNFJTOOMIR-UHFFFAOYSA-M 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 229940057429 sorbitan isostearate Drugs 0.000 description 1
- 241000894007 species Species 0.000 description 1
- 239000008117 stearic acid Substances 0.000 description 1
- 229940012831 stearyl alcohol Drugs 0.000 description 1
- 150000005846 sugar alcohols Polymers 0.000 description 1
- 229920001059 synthetic polymer Polymers 0.000 description 1
- 230000009967 tasteless effect Effects 0.000 description 1
- TUNFSRHWOTWDNC-UHFFFAOYSA-N tetradecanoic acid Chemical compound CCCCCCCCCCCCCC(O)=O TUNFSRHWOTWDNC-UHFFFAOYSA-N 0.000 description 1
- QEMXHQIAXOOASZ-UHFFFAOYSA-N tetramethylammonium Chemical compound C[N+](C)(C)C QEMXHQIAXOOASZ-UHFFFAOYSA-N 0.000 description 1
- 239000004408 titanium dioxide Substances 0.000 description 1
- 239000003860 topical agent Substances 0.000 description 1
- 239000012049 topical pharmaceutical composition Substances 0.000 description 1
- 235000010487 tragacanth Nutrition 0.000 description 1
- 239000000196 tragacanth Substances 0.000 description 1
- 229940116362 tragacanth Drugs 0.000 description 1
- 125000002948 undecyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
- 210000002700 urine Anatomy 0.000 description 1
- 229940099259 vaseline Drugs 0.000 description 1
- 125000000391 vinyl group Chemical group [H]C([*])=C([H])[H] 0.000 description 1
- 229920002554 vinyl polymer Polymers 0.000 description 1
- 239000001993 wax Substances 0.000 description 1
- 239000011787 zinc oxide Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Dermatology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CH2597/86A CH666621A5 (de) | 1986-06-27 | 1986-06-27 | Topisch applizierbare pharmazeutische zusammensetzungen mit systemischer wirkung. |
Publications (1)
Publication Number | Publication Date |
---|---|
PH26781A true PH26781A (en) | 1992-10-13 |
Family
ID=4237351
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PH35441A PH26781A (en) | 1986-06-27 | 1987-06-22 | Novel pharmaceutical composition for topical application with systemic action |
Country Status (27)
Country | Link |
---|---|
US (1) | US4999379A (it) |
JP (1) | JPS638329A (it) |
KR (1) | KR880000093A (it) |
AT (1) | AT397199B (it) |
AU (1) | AU612323B2 (it) |
BE (1) | BE1000233A4 (it) |
CA (1) | CA1315692C (it) |
CH (1) | CH666621A5 (it) |
DD (1) | DD263448A5 (it) |
DE (1) | DE3720896A1 (it) |
DK (1) | DK326587A (it) |
ES (1) | ES2010224A6 (it) |
FI (1) | FI872808A (it) |
FR (1) | FR2601588B1 (it) |
GB (1) | GB2192539B (it) |
GR (1) | GR871002B (it) |
HU (1) | HU197984B (it) |
IT (1) | IT1216827B (it) |
LU (1) | LU86929A1 (it) |
MY (1) | MY101570A (it) |
NL (1) | NL8701508A (it) |
NO (1) | NO872685L (it) |
NZ (1) | NZ220861A (it) |
PH (1) | PH26781A (it) |
PT (1) | PT85158B (it) |
SE (1) | SE8702642L (it) |
ZA (1) | ZA874621B (it) |
Families Citing this family (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4808414A (en) * | 1986-09-29 | 1989-02-28 | Nelson Research & Development Co. | Amide penetration enhancers for transdermal delivery of systemic agents |
US4902676A (en) * | 1986-09-29 | 1990-02-20 | Nelson Research & Development Co. | Compositions comprising N,N-dialkylalkanamides |
CA1334646C (en) * | 1988-04-08 | 1995-03-07 | James Vanolden Peck | Transdermal penetration enhancers |
JPH04193826A (ja) * | 1990-11-27 | 1992-07-13 | Shirogane Seiyaku Kk | ジクロフェナクナトリウム含有の経皮吸収型消炎・鎮痛貼布剤 |
DE9016291U1 (de) * | 1990-11-30 | 1991-03-28 | Kali-Chemie Pharma Gmbh, 3000 Hannover | Topisch applizierbare Diclofenac-Zubereitungen |
ATE121724T1 (de) * | 1991-02-07 | 1995-05-15 | Heumann Pharma Gmbh & Co | Neue salze der 2-(2,6-dichloranilino)- phenylessigsäure, verfahren zu ihrer herstellung und ihre verwendung für topisch anwendbare pharmazeutische zubereitungen. |
AU2259692A (en) * | 1991-07-03 | 1993-02-11 | Sano Corporation | Composition and method for transdermal delivery of diclofenac |
JP2523428B2 (ja) * | 1992-12-04 | 1996-08-07 | エスエス製薬株式会社 | 消炎鎮痛ゲル製剤 |
US5750141A (en) * | 1993-04-08 | 1998-05-12 | The University Of Queensland | Administration of vaso-active agent and therapeutic agent |
DE4313402A1 (de) * | 1993-04-23 | 1994-10-27 | Hexal Pharma Gmbh | Transdermale Wirkstoffzubereitung |
US5474985A (en) * | 1993-12-22 | 1995-12-12 | The Regents Of The University Of California | Preventing and treating elevated intraocular pressure associated with administered or endogenous steroids using non-steroidal cyclooxygenase inhibitors |
EP0788794A4 (en) * | 1994-08-09 | 2000-06-28 | Tsumura & Co | COMPOSITION FOR PREPARATION FOR EXTERNAL USE |
US5665378A (en) * | 1994-09-30 | 1997-09-09 | Davis; Roosevelt | Transdermal therapeutic formulation |
AU3609795A (en) * | 1994-10-10 | 1996-05-02 | Novartis Ag | Ophthalmic and aural compositions containing diclofenac potassium |
US5674888A (en) * | 1995-06-07 | 1997-10-07 | University Of California | Method for the treatment of a trabecular meshwork whose cells are subject to inhibition of cell division |
US5599535A (en) * | 1995-06-07 | 1997-02-04 | Regents Of The University Of California | Methods for the cyto-protection of the trabecular meshwork |
US5897880A (en) * | 1995-09-29 | 1999-04-27 | Lam Pharmaceuticals, Llc. | Topical drug preparations |
KR19990082208A (ko) * | 1996-02-07 | 1999-11-25 | 오이시 고지 | 디클로페낙 나트륨의 투명 수용액 및 이를 이용한 의약 조성물 |
KR19990026792A (ko) * | 1997-09-26 | 1999-04-15 | 김윤 | 디클로페낙 디에틸암모늄염을 함유한 매트릭스형 패취제제 |
US6586000B2 (en) * | 1999-12-16 | 2003-07-01 | Dermatrends, Inc. | Hydroxide-releasing agents as skin permeation enhancers |
CN1200696C (zh) * | 2000-04-18 | 2005-05-11 | 久光制药株式会社 | 含有抗炎药的贴剂 |
JP4865958B2 (ja) * | 2001-05-23 | 2012-02-01 | 株式会社トクホン | 鎮痛抗炎症局所作用型の貼付剤 |
DE102007038413A1 (de) * | 2007-08-09 | 2009-02-12 | Beiersdorf Ag | Kosmetische Emulgatorkombination |
ITMI20111355A1 (it) | 2011-07-20 | 2013-01-21 | Epifarma Srl | Cerotto transdermico contenente diclofenac e tiocolchicoside |
WO2014068600A1 (en) | 2012-11-02 | 2014-05-08 | Zydus Technologies Limited | Stable transdermal pharmaceutical drug delivery system comprising diclofenac |
US9012402B1 (en) | 2014-06-11 | 2015-04-21 | James Blanchard | Gel for topical delivery of NSAIDs to provide relief of musculoskeletal pain and methods for its preparation |
US10821075B1 (en) | 2017-07-12 | 2020-11-03 | James Blanchard | Compositions for topical application of a medicaments onto a mammalian body surface |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3558690A (en) * | 1965-04-08 | 1971-01-26 | Gelgy Chemical Corp | Substituted derivatives of 2-anilinophenylacetic acids and a process of preparation |
US3989816A (en) * | 1975-06-19 | 1976-11-02 | Nelson Research & Development Company | Vehicle composition containing 1-substituted azacycloheptan-2-ones |
US4405616A (en) * | 1975-06-19 | 1983-09-20 | Nelson Research & Development Company | Penetration enhancers for transdermal drug delivery of systemic agents |
US4316893A (en) * | 1975-06-19 | 1982-02-23 | Nelson Research & Development Co. | Vehicle composition containing 1-substituted azacycloalkan-2-ones |
US4444762A (en) * | 1980-04-04 | 1984-04-24 | Nelson Research & Development Company | Vehicle composition containing 1-substituted azacyclopentan-2-ones |
CH655656B (it) * | 1982-10-07 | 1986-05-15 | ||
CA1225594A (en) * | 1983-05-20 | 1987-08-18 | Jourge Heller | Method for percutaneously administering physiologically active agents |
EP0139127A1 (en) * | 1983-08-22 | 1985-05-02 | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft | Transdermal drug delivery device and its preparation |
DE3344691A1 (de) * | 1983-12-10 | 1985-06-20 | Bayer Ag, 5090 Leverkusen | Wirkstoffabgasesysteme |
JPS60156080A (ja) * | 1984-01-25 | 1985-08-16 | Konishiroku Photo Ind Co Ltd | 温度制御手段を備えた複写装置 |
GB2156215B (en) * | 1984-03-05 | 1988-03-02 | Nitto Electric Ind Co | Percutaneous absorption type adhesive pharmaceutical preparation |
JPH06104624B2 (ja) * | 1986-05-07 | 1994-12-21 | 太郎 小木曽 | 経皮吸収剤 |
-
1986
- 1986-06-27 CH CH2597/86A patent/CH666621A5/de not_active IP Right Cessation
-
1987
- 1987-06-22 PH PH35441A patent/PH26781A/en unknown
- 1987-06-22 MY MYPI87000861A patent/MY101570A/en unknown
- 1987-06-23 GB GB8714625A patent/GB2192539B/en not_active Expired - Lifetime
- 1987-06-24 BE BE8700692A patent/BE1000233A4/fr not_active IP Right Cessation
- 1987-06-24 FI FI872808A patent/FI872808A/fi not_active IP Right Cessation
- 1987-06-24 LU LU86929A patent/LU86929A1/de unknown
- 1987-06-24 PT PT85158A patent/PT85158B/pt not_active IP Right Cessation
- 1987-06-24 IT IT8748097A patent/IT1216827B/it active
- 1987-06-24 DE DE19873720896 patent/DE3720896A1/de not_active Withdrawn
- 1987-06-25 DD DD87304164A patent/DD263448A5/de not_active IP Right Cessation
- 1987-06-25 AT AT0160487A patent/AT397199B/de not_active IP Right Cessation
- 1987-06-25 CA CA000540502A patent/CA1315692C/en not_active Expired - Fee Related
- 1987-06-25 SE SE8702642A patent/SE8702642L/xx not_active Application Discontinuation
- 1987-06-25 FR FR8708961A patent/FR2601588B1/fr not_active Expired - Lifetime
- 1987-06-25 GR GR871002A patent/GR871002B/el unknown
- 1987-06-26 HU HU872910A patent/HU197984B/hu not_active IP Right Cessation
- 1987-06-26 NO NO872685A patent/NO872685L/no unknown
- 1987-06-26 KR KR1019870006498A patent/KR880000093A/ko not_active Application Discontinuation
- 1987-06-26 ES ES8701870A patent/ES2010224A6/es not_active Expired
- 1987-06-26 JP JP62157951A patent/JPS638329A/ja active Pending
- 1987-06-26 NZ NZ220861A patent/NZ220861A/xx unknown
- 1987-06-26 ZA ZA874621A patent/ZA874621B/xx unknown
- 1987-06-26 DK DK326587A patent/DK326587A/da not_active Application Discontinuation
- 1987-06-26 AU AU74762/87A patent/AU612323B2/en not_active Ceased
- 1987-06-26 NL NL8701508A patent/NL8701508A/nl not_active Application Discontinuation
-
1989
- 1989-05-05 US US07/348,325 patent/US4999379A/en not_active Expired - Fee Related
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