PH25896A - Inhibitors of glycoprotein processing having antiretroviral activity - Google Patents

Inhibitors of glycoprotein processing having antiretroviral activity

Info

Publication number
PH25896A
PH25896A PH37019A PH37019A PH25896A PH 25896 A PH25896 A PH 25896A PH 37019 A PH37019 A PH 37019A PH 37019 A PH37019 A PH 37019A PH 25896 A PH25896 A PH 25896A
Authority
PH
Philippines
Prior art keywords
inhibitors
antiretroviral activity
glycoprotein processing
glycoprotein
processing
Prior art date
Application number
PH37019A
Other languages
English (en)
Inventor
Sai Prasad Sunkara
Paul S Liu
Terry L Bowlin
Original Assignee
Merrell Dow Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma
Publication of PH25896A publication Critical patent/PH25896A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7004—Monosaccharides having only carbon, hydrogen and oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
PH37019A 1987-06-08 1988-06-07 Inhibitors of glycoprotein processing having antiretroviral activity PH25896A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US5896287A 1987-06-08 1987-06-08

Publications (1)

Publication Number Publication Date
PH25896A true PH25896A (en) 1991-12-19

Family

ID=22019972

Family Applications (1)

Application Number Title Priority Date Filing Date
PH37019A PH25896A (en) 1987-06-08 1988-06-07 Inhibitors of glycoprotein processing having antiretroviral activity

Country Status (7)

Country Link
EP (1) EP0295538A3 (xx)
JP (1) JP2720169B2 (xx)
KR (1) KR890000097A (xx)
AU (1) AU608853B2 (xx)
DK (1) DK308488A (xx)
PH (1) PH25896A (xx)
ZA (1) ZA883925B (xx)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0252962B1 (en) * 1985-12-23 1995-08-23 Fred Hutchinson Cancer Research Center Regulating retroviral replication, infection, and pathogenesis
US5004746A (en) * 1987-09-29 1991-04-02 Merrell Dow Pharmaceuticals Inc. Anti-retroviral castanospermine esters
US5192772A (en) * 1987-12-09 1993-03-09 Nippon Shinyaku Co. Ltd. Therapeutic agents
GB8827701D0 (en) * 1987-12-09 1988-12-29 Nippon Shinyaku Co Ltd Thrombolytic &c compositions
FR2632526B1 (fr) * 1988-06-10 1994-05-13 Pasteur Institut Composition pharmaceutique active sur les residus glucose de la glycoproteine gp 150
AU618838B2 (en) * 1988-08-10 1992-01-09 Praxis Pharmaceuticals, Inc. Use of castanospermine as an anti-inflammatory and immunosuppressant agent
WO1990001319A1 (en) * 1988-08-10 1990-02-22 The Australian National University Use of castanospermine as an anti-inflammatory and immunosuppressant agent
US5650413A (en) * 1995-06-07 1997-07-22 Glycodesign Inc. Derivatives of swainsonine, processes for their preparation and their use as therapeutic agents
US5908867A (en) * 1996-07-18 1999-06-01 Henry; James P. Reduction of hair growth
AU736668B2 (en) * 1996-10-01 2001-08-02 Glycodesign Inc. Novel 3, 5, and/or 6 substituted analogues of swainsonine, processes for their preparation and their use as therapeutic agents
CA2286766A1 (en) 1997-04-15 1998-10-22 Glycodesign Inc. Alkaloid halide salts of swainsonine and methods of use
EP1023290A1 (en) * 1997-10-24 2000-08-02 Glycodesign Inc. Synthesis of swainsonine salts
CN1290168A (zh) * 1997-12-11 2001-04-04 牛津大学院长校长专家委员会 膜相关病毒复制的抑制
US6670374B1 (en) * 2002-06-11 2003-12-30 The United States Of America As Represented By The Secretary Of Agriculture Swainsonine compounds as inhibitors of toxin receptor expression
GB0501352D0 (en) * 2005-01-21 2005-03-02 Slingsby Jason H Use of glycosylation modulators in combination with membrane fusion inhibitors for treatment of infections caused by viruses bearing glycosylated envelope
AU2006221080A1 (en) * 2005-02-09 2006-09-14 Migenix Inc. Compositions and methods for treating or preventing flaviviridae infections

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0252962B1 (en) * 1985-12-23 1995-08-23 Fred Hutchinson Cancer Research Center Regulating retroviral replication, infection, and pathogenesis
EP0282618A1 (en) * 1987-03-18 1988-09-21 Vereniging Het Nederlands Kanker Instituut 1-Deoxynojirimycin as an anti-HIV therapeutic
DK175094B1 (da) * 1987-12-21 2004-06-01 Monsanto Co Anvendelse af N-butyl-derivatet af deoxynojirimycin til fremstilling af farmaceutisk præparat

Also Published As

Publication number Publication date
JP2720169B2 (ja) 1998-02-25
JPS63310819A (ja) 1988-12-19
AU1739788A (en) 1988-12-08
DK308488D0 (da) 1988-06-07
EP0295538A3 (en) 1991-04-03
KR890000097A (ko) 1989-03-11
AU608853B2 (en) 1991-04-18
EP0295538A2 (en) 1988-12-21
DK308488A (da) 1988-12-09
ZA883925B (en) 1989-02-22

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