PH25652A - Esters of n-alkyl-nortropines, their quaternary derivatives having anti-bronchospatic activity, process for their preparation, pharmaceutical compositions containing them - Google Patents

Esters of n-alkyl-nortropines, their quaternary derivatives having anti-bronchospatic activity, process for their preparation, pharmaceutical compositions containing them

Info

Publication number
PH25652A
PH25652A PH34845A PH34845A PH25652A PH 25652 A PH25652 A PH 25652A PH 34845 A PH34845 A PH 34845A PH 34845 A PH34845 A PH 34845A PH 25652 A PH25652 A PH 25652A
Authority
PH
Philippines
Prior art keywords
nortropines
bronchospatic
esters
alkyl
activity
Prior art date
Application number
PH34845A
Other languages
English (en)
Inventor
Luigi Turbanti
Guido Cerbai
Pisa
Original Assignee
Lab Guidotti
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lab Guidotti filed Critical Lab Guidotti
Publication of PH25652A publication Critical patent/PH25652A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
    • C07D451/06—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
    • C07D451/06—Oxygen atoms
    • C07D451/10—Oxygen atoms acylated by aliphatic or araliphatic carboxylic acids, e.g. atropine, scopolamine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
PH34845A 1986-02-11 1987-02-11 Esters of n-alkyl-nortropines, their quaternary derivatives having anti-bronchospatic activity, process for their preparation, pharmaceutical compositions containing them PH25652A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT8619371A IT1213033B (it) 1986-02-11 1986-02-11 Esteri di n-alchil-nortropine eloro derivati ammonioquaternari aventi attivita'anti-broncospastica, procedimento per la loro preparazione e composizioni farmaceutiche che licontengono.

Publications (1)

Publication Number Publication Date
PH25652A true PH25652A (en) 1991-08-21

Family

ID=11157123

Family Applications (1)

Application Number Title Priority Date Filing Date
PH34845A PH25652A (en) 1986-02-11 1987-02-11 Esters of n-alkyl-nortropines, their quaternary derivatives having anti-bronchospatic activity, process for their preparation, pharmaceutical compositions containing them

Country Status (16)

Country Link
US (1) US4780467A (ko)
EP (1) EP0234400B1 (ko)
JP (1) JPH0723374B2 (ko)
KR (1) KR940009783B1 (ko)
AR (1) AR244225A1 (ko)
AT (1) ATE58734T1 (ko)
CA (1) CA1303043C (ko)
DE (1) DE3766377D1 (ko)
DK (1) DK170254B1 (ko)
GR (1) GR3001228T3 (ko)
IL (1) IL81519A0 (ko)
IN (1) IN165884B (ko)
IT (1) IT1213033B (ko)
NO (1) NO166861C (ko)
PH (1) PH25652A (ko)
ZA (1) ZA87983B (ko)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2706198A (en) * 1952-03-29 1955-04-12 Merck & Co Inc Benzhydryl ethers of tropine and processes of preparation
FR1444661A (fr) * 1960-10-18 1966-07-08 Egyt Gyogyszervegyeszeti Gyar Procédé de préparation de dérivés de p-alkyl-benzyl-tropinium
CH533082A (it) * 1967-10-07 1973-01-31 Guidotti & C Spa Labor Metodo di preparazione di prodotti ad attività antispastica e antiulcera
FR2168881A1 (en) * 1972-01-25 1973-09-07 Synthelabo Tropanol 1-phenylcycloalkane carboxylic ester salts - spasmolytics and cholinergics

Also Published As

Publication number Publication date
CA1303043C (en) 1992-06-09
KR870007929A (ko) 1987-09-23
NO166861B (no) 1991-06-03
DE3766377D1 (de) 1991-01-10
DK170254B1 (da) 1995-07-17
EP0234400B1 (en) 1990-11-28
IT8619371A0 (it) 1986-02-11
GR3001228T3 (en) 1992-07-30
DK66587A (da) 1987-08-12
IN165884B (ko) 1990-02-03
EP0234400A1 (en) 1987-09-02
NO166861C (no) 1991-09-11
NO870515L (no) 1987-08-12
ATE58734T1 (de) 1990-12-15
DK66587D0 (da) 1987-02-10
KR940009783B1 (ko) 1994-10-17
NO870515D0 (no) 1987-02-10
AR244225A1 (es) 1993-10-29
ZA87983B (en) 1987-08-03
IL81519A0 (en) 1987-09-16
JPH0723374B2 (ja) 1995-03-15
US4780467A (en) 1988-10-25
JPS62246572A (ja) 1987-10-27
IT1213033B (it) 1989-12-07

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