DK66587A - Tropinderivater og fremgangsmaade til fremstilling deraf - Google Patents

Tropinderivater og fremgangsmaade til fremstilling deraf

Info

Publication number
DK66587A
DK66587A DK066587A DK66587A DK66587A DK 66587 A DK66587 A DK 66587A DK 066587 A DK066587 A DK 066587A DK 66587 A DK66587 A DK 66587A DK 66587 A DK66587 A DK 66587A
Authority
DK
Denmark
Prior art keywords
tropin
procedures
derivatives
preparing
tropin derivatives
Prior art date
Application number
DK066587A
Other languages
English (en)
Other versions
DK66587D0 (da
DK170254B1 (da
Inventor
Luigi Turbanti
Guido Cerbai
Original Assignee
Guidotti & C Spa Labor
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Guidotti & C Spa Labor filed Critical Guidotti & C Spa Labor
Publication of DK66587D0 publication Critical patent/DK66587D0/da
Publication of DK66587A publication Critical patent/DK66587A/da
Application granted granted Critical
Publication of DK170254B1 publication Critical patent/DK170254B1/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D451/00Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D451/00Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • C07D451/04Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
    • C07D451/06Oxygen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/08Bronchodilators
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D451/00Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • C07D451/04Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
    • C07D451/06Oxygen atoms
    • C07D451/10Oxygen atoms acylated by aliphatic or araliphatic carboxylic acids, e.g. atropine, scopolamine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK066587A 1986-02-11 1987-02-10 N-Alkyl-nortropinestere med phenyl-cyclohexen-carboxylsyre eller -eddikesyre og deres kvaternære ammoniumderivater, fremgangsmåde til deres fremstilling samt præparat indeholdende disse DK170254B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT1937186 1986-02-11
IT8619371A IT1213033B (it) 1986-02-11 1986-02-11 Esteri di n-alchil-nortropine eloro derivati ammonioquaternari aventi attivita'anti-broncospastica, procedimento per la loro preparazione e composizioni farmaceutiche che licontengono.

Publications (3)

Publication Number Publication Date
DK66587D0 DK66587D0 (da) 1987-02-10
DK66587A true DK66587A (da) 1987-08-12
DK170254B1 DK170254B1 (da) 1995-07-17

Family

ID=11157123

Family Applications (1)

Application Number Title Priority Date Filing Date
DK066587A DK170254B1 (da) 1986-02-11 1987-02-10 N-Alkyl-nortropinestere med phenyl-cyclohexen-carboxylsyre eller -eddikesyre og deres kvaternære ammoniumderivater, fremgangsmåde til deres fremstilling samt præparat indeholdende disse

Country Status (16)

Country Link
US (1) US4780467A (da)
EP (1) EP0234400B1 (da)
JP (1) JPH0723374B2 (da)
KR (1) KR940009783B1 (da)
AR (1) AR244225A1 (da)
AT (1) ATE58734T1 (da)
CA (1) CA1303043C (da)
DE (1) DE3766377D1 (da)
DK (1) DK170254B1 (da)
GR (1) GR3001228T3 (da)
IL (1) IL81519A0 (da)
IN (1) IN165884B (da)
IT (1) IT1213033B (da)
NO (1) NO166861C (da)
PH (1) PH25652A (da)
ZA (1) ZA87983B (da)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2706198A (en) * 1952-03-29 1955-04-12 Merck & Co Inc Benzhydryl ethers of tropine and processes of preparation
FR1444661A (fr) * 1960-10-18 1966-07-08 Egyt Gyogyszervegyeszeti Gyar Procédé de préparation de dérivés de p-alkyl-benzyl-tropinium
IL30816A (en) * 1967-10-07 1973-04-30 Guidotti & C Spa Labor 2-phenyl-cyclohexene-3-carboxylic acid,its derivatives and the preparation thereof
FR2168881A1 (en) * 1972-01-25 1973-09-07 Synthelabo Tropanol 1-phenylcycloalkane carboxylic ester salts - spasmolytics and cholinergics

Also Published As

Publication number Publication date
IT1213033B (it) 1989-12-07
IN165884B (da) 1990-02-03
ZA87983B (en) 1987-08-03
GR3001228T3 (en) 1992-07-30
NO870515D0 (no) 1987-02-10
IL81519A0 (en) 1987-09-16
DK66587D0 (da) 1987-02-10
US4780467A (en) 1988-10-25
EP0234400A1 (en) 1987-09-02
KR940009783B1 (ko) 1994-10-17
AR244225A1 (es) 1993-10-29
DK170254B1 (da) 1995-07-17
NO166861B (no) 1991-06-03
DE3766377D1 (de) 1991-01-10
NO166861C (no) 1991-09-11
JPS62246572A (ja) 1987-10-27
NO870515L (no) 1987-08-12
ATE58734T1 (de) 1990-12-15
CA1303043C (en) 1992-06-09
EP0234400B1 (en) 1990-11-28
JPH0723374B2 (ja) 1995-03-15
IT8619371A0 (it) 1986-02-11
KR870007929A (ko) 1987-09-23
PH25652A (en) 1991-08-21

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Legal Events

Date Code Title Description
B1 Patent granted (law 1993)
PBP Patent lapsed