PH23645A - Pharmaceutically active pyrazolo 4,3-c) pyridines and method of use thereof - Google Patents

Pharmaceutically active pyrazolo 4,3-c) pyridines and method of use thereof

Info

Publication number
PH23645A
PH23645A PH28489A PH28489A PH23645A PH 23645 A PH23645 A PH 23645A PH 28489 A PH28489 A PH 28489A PH 28489 A PH28489 A PH 28489A PH 23645 A PH23645 A PH 23645A
Authority
PH
Philippines
Prior art keywords
pyridines
pharmaceutically active
pyrazolo
active pyrazolo
neuroleptic
Prior art date
Application number
PH28489A
Other languages
English (en)
Inventor
Giorgio Winters
Alberto Sala
Domenico Barone
Original Assignee
Lepetit Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lepetit Spa filed Critical Lepetit Spa
Publication of PH23645A publication Critical patent/PH23645A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/72—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D211/74—Oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Anesthesiology (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
PH28489A 1982-02-17 1983-02-08 Pharmaceutically active pyrazolo 4,3-c) pyridines and method of use thereof PH23645A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8204722 1982-02-17

Publications (1)

Publication Number Publication Date
PH23645A true PH23645A (en) 1989-09-27

Family

ID=10528419

Family Applications (1)

Application Number Title Priority Date Filing Date
PH28489A PH23645A (en) 1982-02-17 1983-02-08 Pharmaceutically active pyrazolo 4,3-c) pyridines and method of use thereof

Country Status (16)

Country Link
US (1) US4500525A (enExample)
EP (1) EP0086422B1 (enExample)
JP (1) JPS58152885A (enExample)
KR (1) KR900006853B1 (enExample)
AT (1) ATE30027T1 (enExample)
AU (1) AU563591B2 (enExample)
CA (1) CA1225646A (enExample)
DE (1) DE3373904D1 (enExample)
DK (1) DK27383A (enExample)
ES (3) ES8500273A1 (enExample)
GR (1) GR78080B (enExample)
IE (1) IE55156B1 (enExample)
IL (1) IL67785A0 (enExample)
NZ (1) NZ203302A (enExample)
PH (1) PH23645A (enExample)
ZA (1) ZA83628B (enExample)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5137890A (en) * 1990-02-14 1992-08-11 Ortho Pharmaceutical Corporation 4-phenyl tetrahydropyrido(4,3-d)pyrimidines
US5264576A (en) * 1992-10-22 1993-11-23 Hoechst-Roussel Pharmaceuticals Incorporated Pyrazolo[4,3-c]pyridines which are intermediates
DE19834044A1 (de) * 1998-07-29 2000-02-03 Bayer Ag Neue substituierte Pyrazolderivate
US20070105841A1 (en) * 2000-08-14 2007-05-10 Breitenbucher J G Method for treating allergies using substituted pyrazoles
DK1309591T3 (da) * 2000-08-14 2007-03-26 Ortho Mcneil Pharm Inc Substituerede pyrazoler
US20050101587A9 (en) * 2000-08-14 2005-05-12 Butler Christopher R. Method for treating allergies using substituted pyrazoles
US20070117785A1 (en) * 2000-08-14 2007-05-24 Butler Christopher R Substituted pyrazoles and methods of treatment with substituted pyrazoles
CA2419550A1 (en) 2000-08-14 2002-02-21 Ortho-Mcneil Pharmaceutical, Inc. Substituted pyrazoles
ES2261463T3 (es) 2000-08-14 2006-11-16 Ortho-Mcneil Pharmaceutical, Inc. Pirazoles sustituidos.
US7332494B2 (en) 2000-08-14 2008-02-19 Janssen Pharmaceutica, N.V. Method for treating allergies using substituted pyrazoles
HK1053129A1 (zh) 2000-09-06 2003-10-10 Ortho-Mcneil Pharmaceutical, Inc. 治疗变态反应的方法
CA2421505A1 (en) * 2000-09-06 2002-03-14 Ortho-Mcneil Pharmaceutical, Inc. Method for treating allergies using substituted pyrazoles
RU2286343C2 (ru) * 2001-08-10 2006-10-27 Орто-Макнейл Фармасьютикал, Инк. Замещенные пиразолы
EP1507779A1 (en) * 2002-05-30 2005-02-23 Vertex Pharmaceuticals Incorporated Inhibitors of jak and cdk2 protein kinases
US20060100233A1 (en) * 2002-07-25 2006-05-11 Manuela Villa Bicyclo-pyrazoles active as kinase inhibitors, process for their preparation and pharmaceutical compositions comprising them
EP2243781A1 (en) * 2003-05-30 2010-10-27 Vertex Pharmaceuticals, Inc. Pyrazolopyridine derivatives as inhibitors of JAK and CDK2 protein kinases
KR101151653B1 (ko) 2003-09-17 2012-06-28 얀센 파마슈티카 엔.브이. 융합된 헤테로사이클릭 화합물
WO2005030776A1 (en) 2003-09-23 2005-04-07 Vertex Pharmaceuticals Incorporated Pyrazolopyrrole derivatives as protein kinase inhibitors
KR100838692B1 (ko) 2007-07-11 2008-06-16 한국화학연구원 7-(3′,4′-디알콕시페닐)-4,5,6,7-테트라히드로피라졸로[1,5-ａ]피리미딘 화합물, 이의 제조방법 및 이를 포함하는천식 및 만성폐쇄성 폐질환을 포함한 염증관련 질환,관절염, 아토피 피부염, 암 및 뇌질환의 치료 및 예방을위한 약제학적 조성물
US9242981B2 (en) 2010-09-16 2016-01-26 Merck Sharp & Dohme Corp. Fused pyrazole derivatives as novel ERK inhibitors
EP2755972B1 (en) 2011-09-12 2015-10-28 Sanofi Indanyl-substituted 4,5,6,7-tetrahydro-1h-pyrazolo[4,3-c]pyridines, their use as medicament, and pharmaceutical preparations comprising them
MX2014002968A (es) 2011-09-12 2014-07-09 Sanofi Sa 4,5,6,7 - tetrahidro - 1h - pirazolo [4,3 -c] piridinas sustituidas con indanilo, su uso como medicamento, y preparaciones farmaceuticas que las comprenden.
PT2755973E (pt) 2011-09-16 2016-02-16 Sanofi Sa Piridinas 4,5,6,7-tetra-hidro-1h-pirazolo[4,3-c]substituídas e sua utilização como medicamentos e preparados farmacêuticos que as contenham
BR112014006180A2 (pt) 2011-09-16 2017-04-11 Sanofi Sa 4, 5, 6, 7-tetraidro-1h-pirazol [4, 3-c] piridinas substituídas, seu uso como medicamento e preparações farmacêuticas que compreendem as mesmas
CN107531691A (zh) 2014-12-30 2018-01-02 诺维拉治疗公司 治疗乙型肝炎感染的衍生物和方法
CN109476663B (zh) * 2016-05-24 2021-11-09 基因泰克公司 用于治疗癌症的吡唑并吡啶衍生物
TW201806956A (zh) 2016-06-29 2018-03-01 諾維拉治療公司 二氮呯酮衍生物及治療ｂ型肝炎感染之方法
US10975077B2 (en) 2016-06-29 2021-04-13 Novira Therapeutics, Inc. Diazepinone derivatives and their use in the treatment of hepatitis B infections
MX392259B (es) 2017-05-31 2025-03-24 Chemocentryx Inc ANILLOS 6-5 FUSIONADOS COMO INHIBIDORES C5a
US10828285B2 (en) * 2017-12-22 2020-11-10 Chemocentryx, Inc. Diaryl substituted 6,5-fused ring compounds as C5aR inhibitors

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3852279A (en) * 1973-03-12 1974-12-03 Squibb & Sons Inc 7-substituted -3,3a,4,5,6,7-hexahydro-3-substituted-2h- pyrazolo (4,3-c)pyridines

Also Published As

Publication number Publication date
KR840003636A (ko) 1984-09-15
IE55156B1 (en) 1990-06-20
ES8507546A1 (es) 1985-09-01
AU563591B2 (en) 1987-07-16
ATE30027T1 (de) 1987-10-15
DE3373904D1 (en) 1987-11-05
KR900006853B1 (ko) 1990-09-22
AU1130583A (en) 1983-08-25
ES531980A0 (es) 1985-09-01
ZA83628B (en) 1983-12-28
EP0086422B1 (en) 1987-09-30
EP0086422A2 (en) 1983-08-24
US4500525A (en) 1985-02-19
IL67785A0 (en) 1983-05-15
ES8507547A1 (es) 1985-09-01
JPS58152885A (ja) 1983-09-10
ES519832A0 (es) 1984-10-01
DK27383D0 (da) 1983-01-25
NZ203302A (en) 1986-08-08
IE830328L (en) 1983-08-17
JPH0412269B2 (enExample) 1992-03-04
DK27383A (da) 1983-08-18
CA1225646A (en) 1987-08-18
ES8500273A1 (es) 1984-10-01
ES531981A0 (es) 1985-09-01
EP0086422A3 (en) 1984-03-28
GR78080B (enExample) 1984-09-26

Similar Documents

Publication Publication Date Title
PH23645A (en) Pharmaceutically active pyrazolo 4,3-c) pyridines and method of use thereof
IL72120A (en) 2-pyrimidinyl-1-piperazine derivatives,their preparation and pharmaceutical compositions containing them
YU211087A (en) Process for obtaining new n-substituted benzimidazolic derivatives
HUT38897A (en) Process for producing pharmaceutically active substituted benzamides and pharmaceutical compositions containing them as active agents
PT77370A (en) Process for preparing new pyrazolo <3,4-b> piridine derivatives and pharmaceutical preparations containing the same
MX9403088A (es) Composiciones farmaceuticas que contienen deriva- dos de indol y metodos de uso.
JO1406B1 (en) Chemical compounds
ZA848140B (en) New benzenesulfonyl-lactams,process for their preparation and their use as active substances of pharmaceutical compositions
ES8305684A1 (es) Procedimiento para la obtencion de derivados aminopropanolicos de 2-hidroxi b-fenil-propiofenonas.
ZA848141B (en) New cyclic benzensulfonamides,process for their preparation and their use as active substance of pharmaceutical compositions
AU573899B2 (en) Pyrazolo(3,4-b)-pyridine amided
HUT39437A (en) Process for producing new morpholinol derivatives and pharmaceutical compositions containing them as active agents
ES8800217A1 (es) Procedimiento para la preparacion de acidos 4-(isoxazolil)-tiazol-2-oxamicos y sus derivados
ES8802612A1 (es) Procedimiento para preparar derivados de benzisoselenazolilo
PT76734A (en) Process for preparing therapeutically active dihydropyridines of intermediates for the process and of pharmaceutical compositions containing the same
ES8407021A1 (es) Un procedimiento para la preparacion de derivados de acido 5-oxo-2-pirrolidinpropanoico.
IL68194A0 (en) Pharmaceutical preparation containing indolizino indole derivatives,novel compounds of this type and process for their preparation
ES8502868A1 (es) Procedimiento para preparar 2-alquiltio-1-aminoalquil-2-pirrolin-3-carbonitrilos