PH21048A - Tryptamine derivatives, pharmaceutical composition containing said compounds and method of use thereof - Google Patents

Tryptamine derivatives, pharmaceutical composition containing said compounds and method of use thereof

Info

Publication number
PH21048A
PH21048A PH32653A PH32653A PH21048A PH 21048 A PH21048 A PH 21048A PH 32653 A PH32653 A PH 32653A PH 32653 A PH32653 A PH 32653A PH 21048 A PH21048 A PH 21048A
Authority
PH
Philippines
Prior art keywords
lower alkyl
phenyl
compounds
hydrogen
pharmaceutical composition
Prior art date
Application number
PH32653A
Other languages
English (en)
Inventor
Glaser Thomas
Raddatz Siegfried
Traber Joerg
George Allen
Original Assignee
Troponwerke Gmbh & Co Kg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Troponwerke Gmbh & Co Kg filed Critical Troponwerke Gmbh & Co Kg
Publication of PH21048A publication Critical patent/PH21048A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/10Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • C07D209/16Tryptamines

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Saccharide Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Indole Compounds (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
PH32653A 1984-08-17 1985-08-16 Tryptamine derivatives, pharmaceutical composition containing said compounds and method of use thereof PH21048A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19843430284 DE3430284A1 (de) 1984-08-17 1984-08-17 Neue tryptamin-derivate, ein verfahren zu ihrer herstellung und ihre verwendung

Publications (1)

Publication Number Publication Date
PH21048A true PH21048A (en) 1987-07-03

Family

ID=6243280

Family Applications (1)

Application Number Title Priority Date Filing Date
PH32653A PH21048A (en) 1984-08-17 1985-08-16 Tryptamine derivatives, pharmaceutical composition containing said compounds and method of use thereof

Country Status (19)

Country Link
US (1) US4870085A (da)
EP (1) EP0171728B1 (da)
JP (1) JPS6169774A (da)
KR (1) KR910006637B1 (da)
CN (1) CN85101761A (da)
AT (1) ATE41930T1 (da)
AU (1) AU580321B2 (da)
DE (2) DE3430284A1 (da)
DK (1) DK374085A (da)
ES (1) ES8801824A1 (da)
FI (1) FI853134L (da)
GR (1) GR851986B (da)
HU (1) HU195208B (da)
IL (1) IL76088A (da)
NO (1) NO165343C (da)
NZ (1) NZ213104A (da)
PH (1) PH21048A (da)
PT (1) PT80954B (da)
ZA (1) ZA856227B (da)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4808581A (en) * 1986-03-17 1989-02-28 Glaxo Group Limited Imidazolyl- indolylpropanones as 5-HT3 receptor antagonists
DE3771376D1 (de) * 1986-03-17 1991-08-22 Glaxo Group Ltd Indol-derivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zusammensetzungen.
US5162375A (en) * 1988-05-06 1992-11-10 Beecham Group P.L.C. Treatment of neuronal degeneration with 5HT1A agonists
GB8810748D0 (en) * 1988-05-06 1988-06-08 Beecham Wuelfing Gmbh & Co Kg Novel treatment
GB8819024D0 (en) * 1988-08-10 1988-09-14 Glaxo Group Ltd Chemical compounds
IL114690A (en) * 1990-06-07 1997-02-18 Wellcome Found Antimigraine oxazolidinone substituted indole derivatives
US5317103A (en) * 1991-01-15 1994-05-31 Merck Sharp & Dohme Limited Indole-substituted five-membered heteroaromatic compounds as 5-HT1 agonists
CZ283018B6 (cs) * 1991-02-01 1997-12-17 Merck Sharp And Dohme Limited Deriváty imidazolu, triazolu a tetrazolu a farmaceutické přípravky na jejich bázi
IL106445A (en) * 1992-07-30 1998-01-04 Merck Sharp & Dohme History of 1,2,4-Trans-Triazole 4-Transform, Preparation and Pharmaceutical Preparations Containing Them
DK139593D0 (da) * 1993-12-16 1993-12-16 Lundbeck & Co As H Compounds
US5854268A (en) * 1994-08-02 1998-12-29 Merck Sharp & Dohme, Ltd. Azetidine, pyrrolidine and piperidine derivatives
FR2733984B1 (fr) * 1995-05-10 1997-07-04 Rhone Poulenc Rorer Sa Derives de tryptamine, leur preparation et les medicaments les contenant
US5998462A (en) * 1996-12-16 1999-12-07 Allelix Biopharmaceuticals Inc. 5-alkyl indole compounds
US5856510A (en) * 1996-12-16 1999-01-05 Allelix Biopharmaceuticals Inc. 5-alkenyl and 5-alkynyl indole compounds
US6100291A (en) * 1998-03-16 2000-08-08 Allelix Biopharmaceuticals Inc. Pyrrolidine-indole compounds having 5-HT6 affinity
US6133287A (en) * 1998-03-24 2000-10-17 Allelix Biopharmaceuticals Inc. Piperidine-indole compounds having 5-HT6 affinity
AU779073B2 (en) * 1998-12-23 2005-01-06 Nps Allelix Corp. Indole and indolizidine derivatives for the treatment of migraine
TW200505900A (en) * 2000-04-28 2005-02-16 Acadia Pharm Inc Muscarinic agonists
CN103183629A (zh) * 2013-03-15 2013-07-03 张家港威胜生物医药有限公司 一种重要医药化工中间体5-溴吲哚高效合成工艺
CN104292145A (zh) * 2014-10-12 2015-01-21 湖南华腾制药有限公司 一种6-溴吲哚衍生物的制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3183235A (en) * 1961-06-27 1965-05-11 Sterling Drug Inc 1-[3-, 2-, and 1-indolyl-lower-alkanoyl] piperidines
US3821387A (en) * 1965-10-23 1974-06-28 Robins Co Inc A H The treatment of parkinsonism with 3-(omega-substituted alkyl)-indoles
US3907812A (en) * 1969-07-16 1975-09-23 Sumitomo Chemical Co Butyrophenone derivatives
US3732248A (en) * 1969-12-15 1973-05-08 Pfizer 3-substituted-1-phenyl indolinones
BE795457A (fr) * 1972-02-16 1973-08-16 Clin Midy Amines indoliques, leur preparation et leur application en therapeutiques
FR2506310A1 (fr) * 1981-05-22 1982-11-26 Pharmindustrie ((alkyl- et alcenyl-3 piperidyl-4)-2 ethyl)-3 indoles et leur utilisation comme medicaments
FR2506309A1 (fr) * 1981-05-22 1982-11-26 Pharmindustrie ((tetra- et hexahydro pyridyl-4)-2 ethyl)-3 indoles et leur utilisation comme medicaments

Also Published As

Publication number Publication date
CN85101761A (zh) 1987-02-04
US4870085A (en) 1989-09-26
FI853134A0 (fi) 1985-08-15
DE3569242D1 (en) 1989-05-11
PT80954A (de) 1985-09-01
KR870002124A (ko) 1987-03-30
IL76088A0 (en) 1985-12-31
HUT39443A (en) 1986-09-29
AU580321B2 (en) 1989-01-12
IL76088A (en) 1990-03-19
NZ213104A (en) 1988-07-28
ATE41930T1 (de) 1989-04-15
DK374085A (da) 1986-02-18
PT80954B (pt) 1987-12-30
AU4597185A (en) 1986-02-20
FI853134L (fi) 1986-02-18
NO165343C (no) 1991-01-30
ES8801824A1 (es) 1988-02-16
GR851986B (da) 1985-12-10
EP0171728B1 (de) 1989-04-05
NO853036L (no) 1986-02-18
EP0171728A1 (de) 1986-02-19
NO165343B (no) 1990-10-22
DE3430284A1 (de) 1986-02-27
ES546091A0 (es) 1988-02-16
DK374085D0 (da) 1985-08-16
KR910006637B1 (ko) 1991-08-29
ZA856227B (en) 1986-04-30
HU195208B (en) 1988-04-28
JPS6169774A (ja) 1986-04-10

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