ZA856227B - New tryptamine derivatives,a process for their preparation,and their use - Google Patents
New tryptamine derivatives,a process for their preparation,and their useInfo
- Publication number
- ZA856227B ZA856227B ZA856227A ZA856227A ZA856227B ZA 856227 B ZA856227 B ZA 856227B ZA 856227 A ZA856227 A ZA 856227A ZA 856227 A ZA856227 A ZA 856227A ZA 856227 B ZA856227 B ZA 856227B
- Authority
- ZA
- South Africa
- Prior art keywords
- lower alkyl
- phenyl
- hydrogen
- preparation
- amino
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
- C07D209/16—Tryptamines
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Biomedical Technology (AREA)
- Anesthesiology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Saccharide Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Indole Compounds (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19843430284 DE3430284A1 (de) | 1984-08-17 | 1984-08-17 | Neue tryptamin-derivate, ein verfahren zu ihrer herstellung und ihre verwendung |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA856227B true ZA856227B (en) | 1986-04-30 |
Family
ID=6243280
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA856227A ZA856227B (en) | 1984-08-17 | 1985-08-16 | New tryptamine derivatives,a process for their preparation,and their use |
Country Status (19)
Country | Link |
---|---|
US (1) | US4870085A (da) |
EP (1) | EP0171728B1 (da) |
JP (1) | JPS6169774A (da) |
KR (1) | KR910006637B1 (da) |
CN (1) | CN85101761A (da) |
AT (1) | ATE41930T1 (da) |
AU (1) | AU580321B2 (da) |
DE (2) | DE3430284A1 (da) |
DK (1) | DK374085A (da) |
ES (1) | ES8801824A1 (da) |
FI (1) | FI853134L (da) |
GR (1) | GR851986B (da) |
HU (1) | HU195208B (da) |
IL (1) | IL76088A (da) |
NO (1) | NO165343C (da) |
NZ (1) | NZ213104A (da) |
PH (1) | PH21048A (da) |
PT (1) | PT80954B (da) |
ZA (1) | ZA856227B (da) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4808581A (en) * | 1986-03-17 | 1989-02-28 | Glaxo Group Limited | Imidazolyl- indolylpropanones as 5-HT3 receptor antagonists |
DK134687A (da) * | 1986-03-17 | 1987-09-18 | Glaxo Group Ltd | Indolderivater |
US5162375A (en) * | 1988-05-06 | 1992-11-10 | Beecham Group P.L.C. | Treatment of neuronal degeneration with 5HT1A agonists |
GB8810748D0 (en) * | 1988-05-06 | 1988-06-08 | Beecham Wuelfing Gmbh & Co Kg | Novel treatment |
GB8819024D0 (en) * | 1988-08-10 | 1988-09-14 | Glaxo Group Ltd | Chemical compounds |
MC2210A1 (fr) * | 1990-06-07 | 1992-11-26 | Wellcome Found | Composes heterocycliques therapeutiques,leur utilisation et procede pour les preparer |
US5317103A (en) * | 1991-01-15 | 1994-05-31 | Merck Sharp & Dohme Limited | Indole-substituted five-membered heteroaromatic compounds as 5-HT1 agonists |
CZ283018B6 (cs) * | 1991-02-01 | 1997-12-17 | Merck Sharp And Dohme Limited | Deriváty imidazolu, triazolu a tetrazolu a farmaceutické přípravky na jejich bázi |
IL106445A (en) * | 1992-07-30 | 1998-01-04 | Merck Sharp & Dohme | History of 1,2,4-Trans-Triazole 4-Transform, Preparation and Pharmaceutical Preparations Containing Them |
DK139593D0 (da) * | 1993-12-16 | 1993-12-16 | Lundbeck & Co As H | Compounds |
CA2195107A1 (en) * | 1994-08-02 | 1996-02-15 | Richard Alexander Jelley | Azetidine, pyrrolidine and piperidine derivatives |
FR2733984B1 (fr) * | 1995-05-10 | 1997-07-04 | Rhone Poulenc Rorer Sa | Derives de tryptamine, leur preparation et les medicaments les contenant |
US5998462A (en) * | 1996-12-16 | 1999-12-07 | Allelix Biopharmaceuticals Inc. | 5-alkyl indole compounds |
US5856510A (en) * | 1996-12-16 | 1999-01-05 | Allelix Biopharmaceuticals Inc. | 5-alkenyl and 5-alkynyl indole compounds |
US6100291A (en) * | 1998-03-16 | 2000-08-08 | Allelix Biopharmaceuticals Inc. | Pyrrolidine-indole compounds having 5-HT6 affinity |
US6133287A (en) * | 1998-03-24 | 2000-10-17 | Allelix Biopharmaceuticals Inc. | Piperidine-indole compounds having 5-HT6 affinity |
EP1140074A1 (en) * | 1998-12-23 | 2001-10-10 | NPS Allelix Corp. | Indole and indolizidine derivatives for the treatment of migraine |
ES2238437T3 (es) * | 2000-04-28 | 2005-09-01 | Acadia Pharmaceuticals Inc. | Agonistas muscarinicos. |
CN103183629A (zh) * | 2013-03-15 | 2013-07-03 | 张家港威胜生物医药有限公司 | 一种重要医药化工中间体5-溴吲哚高效合成工艺 |
CN104292145A (zh) * | 2014-10-12 | 2015-01-21 | 湖南华腾制药有限公司 | 一种6-溴吲哚衍生物的制备方法 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3183235A (en) * | 1961-06-27 | 1965-05-11 | Sterling Drug Inc | 1-[3-, 2-, and 1-indolyl-lower-alkanoyl] piperidines |
US3821387A (en) * | 1965-10-23 | 1974-06-28 | Robins Co Inc A H | The treatment of parkinsonism with 3-(omega-substituted alkyl)-indoles |
US3907812A (en) * | 1969-07-16 | 1975-09-23 | Sumitomo Chemical Co | Butyrophenone derivatives |
US3732248A (en) * | 1969-12-15 | 1973-05-08 | Pfizer | 3-substituted-1-phenyl indolinones |
BE795457A (fr) * | 1972-02-16 | 1973-08-16 | Clin Midy | Amines indoliques, leur preparation et leur application en therapeutiques |
FR2506310A1 (fr) * | 1981-05-22 | 1982-11-26 | Pharmindustrie | ((alkyl- et alcenyl-3 piperidyl-4)-2 ethyl)-3 indoles et leur utilisation comme medicaments |
FR2506309A1 (fr) * | 1981-05-22 | 1982-11-26 | Pharmindustrie | ((tetra- et hexahydro pyridyl-4)-2 ethyl)-3 indoles et leur utilisation comme medicaments |
-
1984
- 1984-08-17 DE DE19843430284 patent/DE3430284A1/de not_active Withdrawn
-
1985
- 1985-04-01 CN CN198585101761A patent/CN85101761A/zh active Pending
- 1985-07-31 NO NO853036A patent/NO165343C/no unknown
- 1985-08-05 DE DE8585109808T patent/DE3569242D1/de not_active Expired
- 1985-08-05 AT AT85109808T patent/ATE41930T1/de not_active IP Right Cessation
- 1985-08-05 EP EP85109808A patent/EP0171728B1/de not_active Expired
- 1985-08-09 AU AU45971/85A patent/AU580321B2/en not_active Ceased
- 1985-08-12 ES ES546091A patent/ES8801824A1/es not_active Expired
- 1985-08-14 PT PT80954A patent/PT80954B/pt not_active IP Right Cessation
- 1985-08-14 IL IL76088A patent/IL76088A/xx unknown
- 1985-08-14 NZ NZ213104A patent/NZ213104A/xx unknown
- 1985-08-14 GR GR851986A patent/GR851986B/el unknown
- 1985-08-15 FI FI853134A patent/FI853134L/fi not_active Application Discontinuation
- 1985-08-16 JP JP60179515A patent/JPS6169774A/ja active Pending
- 1985-08-16 ZA ZA856227A patent/ZA856227B/xx unknown
- 1985-08-16 HU HU853174A patent/HU195208B/hu not_active IP Right Cessation
- 1985-08-16 PH PH32653A patent/PH21048A/en unknown
- 1985-08-16 DK DK374085A patent/DK374085A/da not_active Application Discontinuation
- 1985-08-16 KR KR1019850005903A patent/KR910006637B1/ko active IP Right Grant
-
1988
- 1988-03-30 US US07/175,066 patent/US4870085A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
ATE41930T1 (de) | 1989-04-15 |
CN85101761A (zh) | 1987-02-04 |
AU4597185A (en) | 1986-02-20 |
KR910006637B1 (ko) | 1991-08-29 |
US4870085A (en) | 1989-09-26 |
JPS6169774A (ja) | 1986-04-10 |
FI853134L (fi) | 1986-02-18 |
ES546091A0 (es) | 1988-02-16 |
AU580321B2 (en) | 1989-01-12 |
PT80954A (de) | 1985-09-01 |
NO165343B (no) | 1990-10-22 |
DE3569242D1 (en) | 1989-05-11 |
NZ213104A (en) | 1988-07-28 |
PT80954B (pt) | 1987-12-30 |
GR851986B (da) | 1985-12-10 |
ES8801824A1 (es) | 1988-02-16 |
HU195208B (en) | 1988-04-28 |
PH21048A (en) | 1987-07-03 |
DK374085D0 (da) | 1985-08-16 |
DE3430284A1 (de) | 1986-02-27 |
EP0171728A1 (de) | 1986-02-19 |
DK374085A (da) | 1986-02-18 |
EP0171728B1 (de) | 1989-04-05 |
IL76088A0 (en) | 1985-12-31 |
IL76088A (en) | 1990-03-19 |
FI853134A0 (fi) | 1985-08-15 |
HUT39443A (en) | 1986-09-29 |
KR870002124A (ko) | 1987-03-30 |
NO853036L (no) | 1986-02-18 |
NO165343C (no) | 1991-01-30 |
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