PH19104A - Salts of l-proline derivatives and a method for inhibiting angiotension converting enzyme - Google Patents
Salts of l-proline derivatives and a method for inhibiting angiotension converting enzymeInfo
- Publication number
- PH19104A PH19104A PH25401A PH25401A PH19104A PH 19104 A PH19104 A PH 19104A PH 25401 A PH25401 A PH 25401A PH 25401 A PH25401 A PH 25401A PH 19104 A PH19104 A PH 19104A
- Authority
- PH
- Philippines
- Prior art keywords
- inhibiting
- salts
- converting enzyme
- proline derivatives
- angiotension converting
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06139—Dipeptides with the first amino acid being heterocyclic
- C07K5/06173—Dipeptides with the first amino acid being heterocyclic and Glp-amino acid; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/46—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with hetero atoms directly attached to the ring nitrogen atom
- C07D207/50—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06086—Dipeptides with the first amino acid being basic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (10)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US94128978A | 1978-09-11 | 1978-09-11 | |
| US95818078A | 1978-11-06 | 1978-11-06 | |
| US06/064,898 US4690938A (en) | 1979-08-14 | 1979-08-14 | Anti-hypertensive agents |
| US06/064,902 US4690940A (en) | 1979-08-14 | 1979-08-14 | Anti-hypertensive agents |
| US06/064,901 US4695577A (en) | 1979-08-14 | 1979-08-14 | Anti-hypertensive agents |
| US06/064,900 US4690939A (en) | 1979-08-14 | 1979-08-14 | Anti-hypertensive agents |
| US06/064,903 US4698355A (en) | 1979-08-14 | 1979-08-14 | Anti-hypertensive agents |
| US06/064,897 US4690937A (en) | 1979-08-14 | 1979-08-14 | Anti-hypertensive agents |
| US06/064,899 US4698356A (en) | 1979-08-14 | 1979-08-14 | Anti-hypertensive agents |
| US06/156,749 US4692437A (en) | 1978-09-11 | 1980-06-05 | Anti-hypertensive agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PH19104A true PH19104A (en) | 1986-01-02 |
Family
ID=27578299
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PH25401A PH19104A (en) | 1978-09-11 | 1981-03-23 | Salts of l-proline derivatives and a method for inhibiting angiotension converting enzyme |
Country Status (15)
| Country | Link |
|---|---|
| EP (1) | EP0009898B1 (xx) |
| AT (1) | AT390795B (xx) |
| AU (1) | AU532424B2 (xx) |
| BG (1) | BG34463A3 (xx) |
| CS (1) | CS242857B2 (xx) |
| DE (1) | DE2965443D1 (xx) |
| DK (1) | DK376179A (xx) |
| FI (1) | FI71749C (xx) |
| GR (1) | GR73585B (xx) |
| HU (1) | HU187258B (xx) |
| IL (1) | IL58223A (xx) |
| IT (1) | IT1193214B (xx) |
| NZ (1) | NZ191524A (xx) |
| PH (1) | PH19104A (xx) |
| PT (1) | PT70158A (xx) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ZA794723B (en) * | 1978-09-11 | 1980-08-27 | Univ Miami | Anti-hypertensive agents |
| ZA802420B (en) * | 1979-05-18 | 1981-04-29 | Squibb & Sons Inc | Aminoacyl derivatives of mercaptoacyl amino acids |
| PT70158A1 (en) * | 1980-03-03 | 1982-03-01 | Univ Miami | Process for preparing anti-hypertensive agents |
| US4734420A (en) * | 1980-03-05 | 1988-03-29 | University Of Miami | Anti-hypertensive agents |
| US4690936A (en) * | 1980-03-05 | 1987-09-01 | University Of Miami | Anti-hypertensive agents |
| EP0036713B1 (en) * | 1980-03-05 | 1984-01-18 | University Of Miami | Angiotensin converting enzyme inhibitors |
| FR2480747A1 (fr) * | 1980-04-17 | 1981-10-23 | Roques Bernard | Derives d'acides amines et leur application therapeutique |
| US4512979A (en) * | 1981-03-23 | 1985-04-23 | Merck & Co., Inc. | Dipeptides containing thialysine and related amino acids as antihypertensives |
| JPS57209270A (en) * | 1981-06-19 | 1982-12-22 | Chugai Pharmaceut Co Ltd | Proline derivative |
| AT386603B (de) * | 1981-06-19 | 1988-09-26 | Chugai Pharmaceutical Co Ltd | Verfahren zur herstellung von neuen prolinderivaten |
| HUT46044A (en) * | 1986-11-21 | 1988-09-28 | Richter Gedeon Vegyeszet | Process for producing immunstimulant peptides inhibiting multiplication of leukaemic cells and pharmaceutics comprising same |
| CN1081650C (zh) * | 1995-12-27 | 2002-03-27 | 罗纳-普朗克·维斯科苏希公司 | 缩聚物,尤其是聚酰胺6,6后冷凝的方法 |
| ES2424332T3 (es) | 2008-06-14 | 2013-10-01 | Veredus Laboratories Pte Ltd | Secuencias de la gripe |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU509899B2 (en) * | 1976-02-13 | 1980-05-29 | E.R. Squibb & Sons, Inc. | Proline derivatives and related compounds |
| US4053651A (en) * | 1976-05-10 | 1977-10-11 | E. R. Squibb & Sons, Inc. | Compounds and method for alleviating angiotensin related hypertension |
| US4116962A (en) * | 1976-12-03 | 1978-09-26 | E. R. Squibb & Sons, Inc. | Pyrrolidine and piperidine-2-carboxylic acid derivatives |
| US4091024A (en) * | 1976-12-03 | 1978-05-23 | E. R. Squibb & Sons, Inc. | Pyrrolidine and piperidine-2-carboxylic acid derivatives |
| AU518147B2 (en) * | 1976-12-03 | 1981-09-17 | E.R. Squibb & Sons, Inc. | Derivatives of thiazolidine, thiazine and morpholine carboxylic acids |
| US4113715A (en) * | 1977-01-17 | 1978-09-12 | E. R. Squibb & Sons, Inc. | Amino acid derivatives |
| US4108886A (en) * | 1977-03-11 | 1978-08-22 | E. R. Squibb & Sons, Inc. | Thiopropanoylamino acid derivatives |
-
1979
- 1979-09-04 GR GR59962A patent/GR73585B/el unknown
- 1979-09-10 FI FI792806A patent/FI71749C/fi not_active IP Right Cessation
- 1979-09-10 HU HU79MI656A patent/HU187258B/hu not_active IP Right Cessation
- 1979-09-10 NZ NZ191524A patent/NZ191524A/xx unknown
- 1979-09-10 DE DE7979301854T patent/DE2965443D1/de not_active Expired
- 1979-09-10 AU AU50705/79A patent/AU532424B2/en not_active Ceased
- 1979-09-10 DK DK376179A patent/DK376179A/da not_active Application Discontinuation
- 1979-09-10 AT AT0596279A patent/AT390795B/de not_active IP Right Cessation
- 1979-09-10 EP EP79301854A patent/EP0009898B1/en not_active Expired
- 1979-09-10 PT PT197970158A patent/PT70158A/pt unknown
- 1979-09-11 IL IL58223A patent/IL58223A/xx unknown
- 1979-09-11 BG BG044830A patent/BG34463A3/xx unknown
- 1979-09-11 CS CS796150A patent/CS242857B2/cs unknown
- 1979-09-11 IT IT25612/79A patent/IT1193214B/it active
-
1981
- 1981-03-23 PH PH25401A patent/PH19104A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP0009898A1 (en) | 1980-04-16 |
| FI71749B (fi) | 1986-10-31 |
| GR73585B (xx) | 1984-03-26 |
| NZ191524A (en) | 1982-12-07 |
| IL58223A (en) | 1984-01-31 |
| DE2965443D1 (en) | 1983-07-07 |
| CS615079A2 (en) | 1985-08-15 |
| IT1193214B (it) | 1988-06-15 |
| IT7925612A0 (it) | 1979-09-11 |
| ATA596279A (de) | 1989-12-15 |
| CS242857B2 (en) | 1986-05-15 |
| BG34463A3 (en) | 1983-09-15 |
| AU5070579A (en) | 1980-03-20 |
| AU532424B2 (en) | 1983-09-29 |
| FI792806A (fi) | 1980-03-12 |
| EP0009898B1 (en) | 1983-05-18 |
| AT390795B (de) | 1990-06-25 |
| DK376179A (da) | 1980-03-12 |
| HU187258B (en) | 1985-12-28 |
| PT70158A (en) | 1979-09-30 |
| FI71749C (fi) | 1987-02-09 |
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