HU187258B - Process for preparing compopunds with hypotensive activity - Google Patents
Process for preparing compopunds with hypotensive activityInfo
- Publication number
- HU187258B HU187258B HU79MI656A HUMI000656A HU187258B HU 187258 B HU187258 B HU 187258B HU 79MI656 A HU79MI656 A HU 79MI656A HU MI000656 A HUMI000656 A HU MI000656A HU 187258 B HU187258 B HU 187258B
- Authority
- HU
- Hungary
- Prior art keywords
- compopunds
- preparing
- hypotensive activity
- hypotensive
- activity
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06139—Dipeptides with the first amino acid being heterocyclic
- C07K5/06173—Dipeptides with the first amino acid being heterocyclic and Glp-amino acid; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/46—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with hetero atoms directly attached to the ring nitrogen atom
- C07D207/50—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06086—Dipeptides with the first amino acid being basic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US94128978A | 1978-09-11 | 1978-09-11 | |
| US95818078A | 1978-11-06 | 1978-11-06 | |
| US06/064,897 US4690937A (en) | 1979-08-14 | 1979-08-14 | Anti-hypertensive agents |
| US06/064,898 US4690938A (en) | 1979-08-14 | 1979-08-14 | Anti-hypertensive agents |
| US06/064,902 US4690940A (en) | 1979-08-14 | 1979-08-14 | Anti-hypertensive agents |
| US06/064,900 US4690939A (en) | 1979-08-14 | 1979-08-14 | Anti-hypertensive agents |
| US06/064,903 US4698355A (en) | 1979-08-14 | 1979-08-14 | Anti-hypertensive agents |
| US06/064,899 US4698356A (en) | 1979-08-14 | 1979-08-14 | Anti-hypertensive agents |
| US06/064,901 US4695577A (en) | 1979-08-14 | 1979-08-14 | Anti-hypertensive agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HU187258B true HU187258B (en) | 1985-12-28 |
Family
ID=27578299
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU79MI656A HU187258B (en) | 1978-09-11 | 1979-09-10 | Process for preparing compopunds with hypotensive activity |
Country Status (15)
| Country | Link |
|---|---|
| EP (1) | EP0009898B1 (hu) |
| AT (1) | AT390795B (hu) |
| AU (1) | AU532424B2 (hu) |
| BG (1) | BG34463A3 (hu) |
| CS (1) | CS242857B2 (hu) |
| DE (1) | DE2965443D1 (hu) |
| DK (1) | DK376179A (hu) |
| FI (1) | FI71749C (hu) |
| GR (1) | GR73585B (hu) |
| HU (1) | HU187258B (hu) |
| IL (1) | IL58223A (hu) |
| IT (1) | IT1193214B (hu) |
| NZ (1) | NZ191524A (hu) |
| PH (1) | PH19104A (hu) |
| PT (1) | PT70158A (hu) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ZA794723B (en) * | 1978-09-11 | 1980-08-27 | Univ Miami | Anti-hypertensive agents |
| ZA802420B (en) * | 1979-05-18 | 1981-04-29 | Squibb & Sons Inc | Aminoacyl derivatives of mercaptoacyl amino acids |
| PT70158A1 (en) * | 1980-03-03 | 1982-03-01 | Univ Miami | Process for preparing anti-hypertensive agents |
| US4734420A (en) * | 1980-03-05 | 1988-03-29 | University Of Miami | Anti-hypertensive agents |
| US4690936A (en) * | 1980-03-05 | 1987-09-01 | University Of Miami | Anti-hypertensive agents |
| DE3161915D1 (en) * | 1980-03-05 | 1984-02-23 | Univ Miami | Angiotensin converting enzyme inhibitors |
| FR2480747A1 (fr) * | 1980-04-17 | 1981-10-23 | Roques Bernard | Derives d'acides amines et leur application therapeutique |
| US4512979A (en) * | 1981-03-23 | 1985-04-23 | Merck & Co., Inc. | Dipeptides containing thialysine and related amino acids as antihypertensives |
| JPS57209270A (en) * | 1981-06-19 | 1982-12-22 | Chugai Pharmaceut Co Ltd | Proline derivative |
| AT386603B (de) * | 1981-06-19 | 1988-09-26 | Chugai Pharmaceutical Co Ltd | Verfahren zur herstellung von neuen prolinderivaten |
| HUT46044A (en) * | 1986-11-21 | 1988-09-28 | Richter Gedeon Vegyeszet | Process for producing immunstimulant peptides inhibiting multiplication of leukaemic cells and pharmaceutics comprising same |
| CN1081650C (zh) * | 1995-12-27 | 2002-03-27 | 罗纳-普朗克·维斯科苏希公司 | 缩聚物,尤其是聚酰胺6,6后冷凝的方法 |
| WO2009151407A2 (en) | 2008-06-14 | 2009-12-17 | Veredus Laboratories Pte Ltd | Influenza sequences |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU509899B2 (en) * | 1976-02-13 | 1980-05-29 | E.R. Squibb & Sons, Inc. | Proline derivatives and related compounds |
| US4053651A (en) * | 1976-05-10 | 1977-10-11 | E. R. Squibb & Sons, Inc. | Compounds and method for alleviating angiotensin related hypertension |
| US4116962A (en) * | 1976-12-03 | 1978-09-26 | E. R. Squibb & Sons, Inc. | Pyrrolidine and piperidine-2-carboxylic acid derivatives |
| US4091024A (en) * | 1976-12-03 | 1978-05-23 | E. R. Squibb & Sons, Inc. | Pyrrolidine and piperidine-2-carboxylic acid derivatives |
| AU518147B2 (en) * | 1976-12-03 | 1981-09-17 | E.R. Squibb & Sons, Inc. | Derivatives of thiazolidine, thiazine and morpholine carboxylic acids |
| US4113715A (en) * | 1977-01-17 | 1978-09-12 | E. R. Squibb & Sons, Inc. | Amino acid derivatives |
| US4108886A (en) * | 1977-03-11 | 1978-08-22 | E. R. Squibb & Sons, Inc. | Thiopropanoylamino acid derivatives |
-
1979
- 1979-09-04 GR GR59962A patent/GR73585B/el unknown
- 1979-09-10 PT PT197970158A patent/PT70158A/pt unknown
- 1979-09-10 DK DK376179A patent/DK376179A/da not_active Application Discontinuation
- 1979-09-10 AT AT0596279A patent/AT390795B/de not_active IP Right Cessation
- 1979-09-10 EP EP79301854A patent/EP0009898B1/en not_active Expired
- 1979-09-10 AU AU50705/79A patent/AU532424B2/en not_active Ceased
- 1979-09-10 DE DE7979301854T patent/DE2965443D1/de not_active Expired
- 1979-09-10 NZ NZ191524A patent/NZ191524A/xx unknown
- 1979-09-10 HU HU79MI656A patent/HU187258B/hu not_active IP Right Cessation
- 1979-09-10 FI FI792806A patent/FI71749C/fi not_active IP Right Cessation
- 1979-09-11 BG BG044830A patent/BG34463A3/xx unknown
- 1979-09-11 CS CS796150A patent/CS242857B2/cs unknown
- 1979-09-11 IT IT25612/79A patent/IT1193214B/it active
- 1979-09-11 IL IL58223A patent/IL58223A/xx unknown
-
1981
- 1981-03-23 PH PH25401A patent/PH19104A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| PT70158A (en) | 1979-09-30 |
| IT7925612A0 (it) | 1979-09-11 |
| FI71749C (fi) | 1987-02-09 |
| IL58223A (en) | 1984-01-31 |
| DK376179A (da) | 1980-03-12 |
| GR73585B (hu) | 1984-03-26 |
| CS615079A2 (en) | 1985-08-15 |
| AU5070579A (en) | 1980-03-20 |
| EP0009898B1 (en) | 1983-05-18 |
| IT1193214B (it) | 1988-06-15 |
| AU532424B2 (en) | 1983-09-29 |
| NZ191524A (en) | 1982-12-07 |
| BG34463A3 (en) | 1983-09-15 |
| CS242857B2 (en) | 1986-05-15 |
| DE2965443D1 (en) | 1983-07-07 |
| AT390795B (de) | 1990-06-25 |
| ATA596279A (de) | 1989-12-15 |
| FI792806A (fi) | 1980-03-12 |
| PH19104A (en) | 1986-01-02 |
| FI71749B (fi) | 1986-10-31 |
| EP0009898A1 (en) | 1980-04-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| HU90 | Patent valid on 900628 | ||
| HMM4 | Cancellation of final prot. due to non-payment of fee |