PH18965A - Gnrh antagonists,pharmaceutical compositions containing the same and method of use thereof - Google Patents

Gnrh antagonists,pharmaceutical compositions containing the same and method of use thereof

Info

Publication number
PH18965A
PH18965A PH27170A PH27170A PH18965A PH 18965 A PH18965 A PH 18965A PH 27170 A PH27170 A PH 27170A PH 27170 A PH27170 A PH 27170A PH 18965 A PH18965 A PH 18965A
Authority
PH
Philippines
Prior art keywords
phe
nal
pro
same
pharmaceutical compositions
Prior art date
Application number
PH27170A
Other languages
English (en)
Inventor
Jean Eduard Frederic Rivier
Wylie Walker Vale Jr
Original Assignee
Salt Inst For Biolog Studi
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Salt Inst For Biolog Studi filed Critical Salt Inst For Biolog Studi
Publication of PH18965A publication Critical patent/PH18965A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/04General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/16Oxytocins; Vasopressins; Related peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/23Luteinising hormone-releasing hormone [LHRH]; Related peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00Peptide or protein sequence
    • Y10S930/01Peptide or protein sequence
    • Y10S930/13Luteinizing hormone-releasing hormone; related peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Endocrinology (AREA)
  • Analytical Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PH27170A 1981-04-21 1982-04-21 Gnrh antagonists,pharmaceutical compositions containing the same and method of use thereof PH18965A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/256,063 US4409208A (en) 1980-04-15 1981-04-21 GnRH antagonists

Publications (1)

Publication Number Publication Date
PH18965A true PH18965A (en) 1985-11-26

Family

ID=22970967

Family Applications (1)

Application Number Title Priority Date Filing Date
PH27170A PH18965A (en) 1981-04-21 1982-04-21 Gnrh antagonists,pharmaceutical compositions containing the same and method of use thereof

Country Status (20)

Country Link
US (1) US4409208A (fr)
EP (1) EP0063423B1 (fr)
JP (1) JPS57181047A (fr)
KR (1) KR830010052A (fr)
AT (1) ATE14886T1 (fr)
AU (1) AU551892B2 (fr)
CA (1) CA1241950A (fr)
CS (1) CS228924B2 (fr)
DD (1) DD202694A5 (fr)
DE (1) DE3265349D1 (fr)
DK (1) DK151033C (fr)
ES (1) ES511525A0 (fr)
GR (1) GR75542B (fr)
HU (1) HU186007B (fr)
IE (1) IE52442B1 (fr)
IL (1) IL65371A (fr)
NO (1) NO821274L (fr)
NZ (1) NZ200125A (fr)
PH (1) PH18965A (fr)
ZA (1) ZA822053B (fr)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58162562A (ja) * 1982-03-05 1983-09-27 シンテツクス・(ユ−・エス・エイ)・インコ−ポレ−テツド Lhrhのノナペプチド及びデカペプチドアナロ−グ
IL70888A0 (en) * 1983-03-10 1984-05-31 Salk Inst For Biological Studi Gn rh antagonist peptides and pharmaceutical compositions containing them
US4547370A (en) * 1983-11-29 1985-10-15 The Salk Institute For Biological Studies GnRH Antagonists
IL74827A (en) * 1984-05-21 1989-06-30 Salk Inst For Biological Studi Peptides active as gnrh antagonists and pharmaceutical compositions containing them
DE3634435A1 (de) * 1986-10-09 1988-04-14 Hoechst Ag Analoga von gonadoliberin mit verbesserter loeslichkeit, verfahren zu deren herstellung, diese enthaltende mittel und ihre verwendung
WO1988007056A1 (fr) * 1987-03-10 1988-09-22 Eastern Virginia Medical Authority PROCEDE ET KIT CONTRACEPTION AVEC UN ANTAGONISTE DE GnRH ET DE LA PROGESTINE
US5068221A (en) * 1989-05-09 1991-11-26 Mathias John R Treatment of motility disorders with a gnrh analog
US5434136A (en) * 1990-12-14 1995-07-18 Mathias; John R. Treatment of motility disorders with a GNRH analog
US5502035A (en) * 1993-08-06 1996-03-26 Tap Holdings Inc. N-terminus modified analogs of LHRH
US5843901A (en) * 1995-06-07 1998-12-01 Advanced Research & Technology Institute LHRH antagonist peptides
MY150763A (en) 2006-10-24 2014-02-28 Repros Therapeutics Inc Compositions and methods for suppressing endometrial proliferation
US20220257695A1 (en) 2017-03-31 2022-08-18 Institut National De La Sante Et De La Recherche Medicale (Inserm) A gnrh antagonist for use in the treatment of a women affected with polycystic ovary syndrome

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PH11571A (en) * 1973-10-03 1978-03-31 American Home Prod P-gui-d-phe-trp-ser-tyr-d-ala-leu-arg-pro-gly-nh2,its non-toxic salts and method of use thereof
US3933782A (en) * 1974-11-14 1976-01-20 American Home Products Corporation (N-Acetyl)-Pro-D-Phe-Trp-Ser-Tyr-D-Ala-Leu-Arg-Pro-NHEt and intermediates
NZ188987A (en) * 1977-11-30 1982-02-23 Salk Inst For Biological Studi Peptide analogues of luteinizing hormone releasing factor
US4234571A (en) * 1979-06-11 1980-11-18 Syntex (U.S.A.) Inc. Nonapeptide and decapeptide derivatives of luteinizing hormone releasing hormone
GB2053229B (en) * 1979-06-13 1983-03-02 Schally Andrew Victor Lh-rh antagonists
US4253997A (en) * 1979-12-17 1981-03-03 American Home Products Corporation Anti-ovulatory decapeptides
NZ196558A (en) * 1980-04-15 1984-10-19 Salk Inst For Biological Studi Lrf antagonists and pharmaceutical compositions

Also Published As

Publication number Publication date
ATE14886T1 (de) 1985-08-15
ES8307720A1 (es) 1983-07-16
AU551892B2 (en) 1986-05-15
IE820819L (en) 1982-10-21
IE52442B1 (en) 1987-10-28
HU186007B (en) 1985-05-28
NO821274L (no) 1982-10-22
IL65371A0 (en) 1982-05-31
KR830010052A (ko) 1983-12-24
AU8283882A (en) 1982-10-28
NZ200125A (en) 1984-10-19
DK173082A (da) 1982-10-22
DK151033C (da) 1988-03-14
DD202694A5 (de) 1983-09-28
US4409208A (en) 1983-10-11
GR75542B (fr) 1984-07-27
DE3265349D1 (en) 1985-09-19
CA1241950A (fr) 1988-09-13
ES511525A0 (es) 1983-07-16
CS228924B2 (en) 1984-05-14
JPS57181047A (en) 1982-11-08
EP0063423A1 (fr) 1982-10-27
DK151033B (da) 1987-10-12
EP0063423B1 (fr) 1985-08-14
ZA822053B (en) 1983-02-23
IL65371A (en) 1985-12-31

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