DK151033C - Analogifremgangsmaade til fremstilling af lrf-analoge nona- eller decapeptidamider eller ikke-toksiske salte deraf - Google Patents

Analogifremgangsmaade til fremstilling af lrf-analoge nona- eller decapeptidamider eller ikke-toksiske salte deraf

Info

Publication number
DK151033C
DK151033C DK173082A DK173082A DK151033C DK 151033 C DK151033 C DK 151033C DK 173082 A DK173082 A DK 173082A DK 173082 A DK173082 A DK 173082A DK 151033 C DK151033 C DK 151033C
Authority
DK
Denmark
Prior art keywords
phe
analogue
nal
pro
decapeptidamides
Prior art date
Application number
DK173082A
Other languages
English (en)
Other versions
DK173082A (da
DK151033B (da
Inventor
Jean Edouard Frederic Rivier
Jr Wylie Walker Vale
Original Assignee
Salk Inst For Biological Studi
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Salk Inst For Biological Studi filed Critical Salk Inst For Biological Studi
Publication of DK173082A publication Critical patent/DK173082A/da
Publication of DK151033B publication Critical patent/DK151033B/da
Application granted granted Critical
Publication of DK151033C publication Critical patent/DK151033C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/16—Oxytocins; Vasopressins; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/23—Luteinising hormone-releasing hormone [LHRH]; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/13—Luteinizing hormone-releasing hormone; related peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Endocrinology (AREA)
  • Analytical Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK173082A 1981-04-21 1982-04-19 Analogifremgangsmaade til fremstilling af lrf-analoge nona- eller decapeptidamider eller ikke-toksiske salte deraf DK151033C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US25606381 1981-04-21
US06/256,063 US4409208A (en) 1980-04-15 1981-04-21 GnRH antagonists

Publications (3)

Publication Number Publication Date
DK173082A DK173082A (da) 1982-10-22
DK151033B DK151033B (da) 1987-10-12
DK151033C true DK151033C (da) 1988-03-14

Family

ID=22970967

Family Applications (1)

Application Number Title Priority Date Filing Date
DK173082A DK151033C (da) 1981-04-21 1982-04-19 Analogifremgangsmaade til fremstilling af lrf-analoge nona- eller decapeptidamider eller ikke-toksiske salte deraf

Country Status (20)

Country Link
US (1) US4409208A (da)
EP (1) EP0063423B1 (da)
JP (1) JPS57181047A (da)
KR (1) KR830010052A (da)
AT (1) ATE14886T1 (da)
AU (1) AU551892B2 (da)
CA (1) CA1241950A (da)
CS (1) CS228924B2 (da)
DD (1) DD202694A5 (da)
DE (1) DE3265349D1 (da)
DK (1) DK151033C (da)
ES (1) ES511525A0 (da)
GR (1) GR75542B (da)
HU (1) HU186007B (da)
IE (1) IE52442B1 (da)
IL (1) IL65371A (da)
NO (1) NO821274L (da)
NZ (1) NZ200125A (da)
PH (1) PH18965A (da)
ZA (1) ZA822053B (da)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58162562A (ja) * 1982-03-05 1983-09-27 シンテツクス・（ユ−・エス・エイ）・インコ−ポレ−テツド Ｌｈｒｈのノナペプチド及びデカペプチドアナロ−グ
IL70888A0 (en) * 1983-03-10 1984-05-31 Salk Inst For Biological Studi Gn rh antagonist peptides and pharmaceutical compositions containing them
US4547370A (en) * 1983-11-29 1985-10-15 The Salk Institute For Biological Studies GnRH Antagonists
IL74827A (en) * 1984-05-21 1989-06-30 Salk Inst For Biological Studi Peptides active as gnrh antagonists and pharmaceutical compositions containing them
DE3634435A1 (de) * 1986-10-09 1988-04-14 Hoechst Ag Analoga von gonadoliberin mit verbesserter loeslichkeit, verfahren zu deren herstellung, diese enthaltende mittel und ihre verwendung
WO1988007056A1 (en) * 1987-03-10 1988-09-22 Eastern Virginia Medical Authority METHOD AND KIT FOR CONTRACEPTION WITH GnRH-ANTAGONIST AND PROGESTIN
US5068221A (en) * 1989-05-09 1991-11-26 Mathias John R Treatment of motility disorders with a gnrh analog
US5434136A (en) * 1990-12-14 1995-07-18 Mathias; John R. Treatment of motility disorders with a GNRH analog
US5502035A (en) * 1993-08-06 1996-03-26 Tap Holdings Inc. N-terminus modified analogs of LHRH
US5843901A (en) * 1995-06-07 1998-12-01 Advanced Research & Technology Institute LHRH antagonist peptides
PL3263112T3 (pl) 2006-10-24 2021-01-11 Allergan Pharmaceuticals International Limited Kompozycje i sposoby tłumienia przerostów endometrium
US20220257695A1 (en) 2017-03-31 2022-08-18 Institut National De La Sante Et De La Recherche Medicale (Inserm) A gnrh antagonist for use in the treatment of a women affected with polycystic ovary syndrome

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PH11571A (en) * 1973-10-03 1978-03-31 American Home Prod P-gui-d-phe-trp-ser-tyr-d-ala-leu-arg-pro-gly-nh2,its non-toxic salts and method of use thereof
US3933782A (en) * 1974-11-14 1976-01-20 American Home Products Corporation (N-Acetyl)-Pro-D-Phe-Trp-Ser-Tyr-D-Ala-Leu-Arg-Pro-NHEt and intermediates
NZ188987A (en) * 1977-11-30 1982-02-23 Salk Inst For Biological Studi Peptide analogues of luteinizing hormone releasing factor
US4234571A (en) * 1979-06-11 1980-11-18 Syntex (U.S.A.) Inc. Nonapeptide and decapeptide derivatives of luteinizing hormone releasing hormone
GB2053229B (en) * 1979-06-13 1983-03-02 Schally Andrew Victor Lh-rh antagonists
US4253997A (en) * 1979-12-17 1981-03-03 American Home Products Corporation Anti-ovulatory decapeptides
NZ196558A (en) * 1980-04-15 1984-10-19 Salk Inst For Biological Studi Lrf antagonists and pharmaceutical compositions

Also Published As

Publication number Publication date
IE820819L (en) 1982-10-21
DK173082A (da) 1982-10-22
EP0063423B1 (en) 1985-08-14
HU186007B (en) 1985-05-28
IL65371A0 (en) 1982-05-31
CA1241950A (en) 1988-09-13
ZA822053B (en) 1983-02-23
IL65371A (en) 1985-12-31
NZ200125A (en) 1984-10-19
DE3265349D1 (en) 1985-09-19
AU8283882A (en) 1982-10-28
PH18965A (en) 1985-11-26
US4409208A (en) 1983-10-11
JPS57181047A (en) 1982-11-08
ES8307720A1 (es) 1983-07-16
EP0063423A1 (en) 1982-10-27
GR75542B (da) 1984-07-27
KR830010052A (ko) 1983-12-24
ES511525A0 (es) 1983-07-16
ATE14886T1 (de) 1985-08-15
CS228924B2 (en) 1984-05-14
IE52442B1 (en) 1987-10-28
AU551892B2 (en) 1986-05-15
DK151033B (da) 1987-10-12
NO821274L (no) 1982-10-22
DD202694A5 (de) 1983-09-28

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Publication Publication Date Title
PT77067A (en) Method for making a peptide or a non-toxic salt thereof
IL73364A0 (en) Peptides which inhibit the secretion of gonadotropins and steroids and pharmaceutical compositions containing them
DE19975052I2 (de) LHRH Antagonisten, deren Herstellung und entsprechende pharmazeutische Zubereitungen.
DK151033C (da) Analogifremgangsmaade til fremstilling af lrf-analoge nona- eller decapeptidamider eller ikke-toksiske salte deraf
ES8207510A1 (es) Un metodo de preparacion de un peptido inhibidor de la liberacion de gonadotropinas por la glandula pituitaria en mamiferos.
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Legal Events

Date Code Title Description
PBP Patent lapsed
B1 Patent granted (law 1993)