PH18803A - 1-cyclopropyl 6 fluoro 1,4 dihydro 4-oxo piperazino quinoline 3 carboxylic acids and antibacterial agent containing these compounds - Google Patents

1-cyclopropyl 6 fluoro 1,4 dihydro 4-oxo piperazino quinoline 3 carboxylic acids and antibacterial agent containing these compounds

Info

Publication number
PH18803A
PH18803A PH28052A PH28052A PH18803A PH 18803 A PH18803 A PH 18803A PH 28052 A PH28052 A PH 28052A PH 28052 A PH28052 A PH 28052A PH 18803 A PH18803 A PH 18803A
Authority
PH
Philippines
Prior art keywords
quinoline
cyclopropyl
dihydro
oxo
fluoro
Prior art date
Application number
PH28052A
Inventor
Klaus Grohe
Hans-Joachim Zeiler
Karl Georg Metzger
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=6145081&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PH18803(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of PH18803A publication Critical patent/PH18803A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Fodder In General (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

1. Claims (for the Contracting States : AT, BE, CH, DE, FR, GB, IT, LI, NL, SE) Cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-piperazino- quinoline-3-carboxylic acids of the formula I see diagramm : EP0078362,P10,F3 in which R denotes hydrogen, methyl, ethyl or beta-hydroxyethyl, and their pharmaceutically usable acid addition salts, alkali metal salts and hydrates, except 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-piperazino- quinoline-3-carboxylic acid and its hydrochloride, 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7- (4-methylpiperazino)-quinoline-3-carboxylic acid and 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7- (4-ethylpiperazino)-quinoline-3-carboxylic acid hydroiodide. 1. Claims (for the Contracting State LU) 1-Cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-piperazino- quinoline-3-carboxylic acids of the formula I see diagramm : EP0078362,P11,F3 in which R denotes hydrogen, methyl, ethyl or beta-hydroxyethyl, and their pharmaceutically usable acid addition salts and hydrates.
PH28052A 1981-10-29 1982-10-28 1-cyclopropyl 6 fluoro 1,4 dihydro 4-oxo piperazino quinoline 3 carboxylic acids and antibacterial agent containing these compounds PH18803A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19813142854 DE3142854A1 (en) 1981-10-29 1981-10-29 1-CYCLOPROPYL-6-FLUOR-1,4-DIHYDRO-4-OXO-7-PIPERAZINO-CHINOLINE-3-CARBONIC ACIDS, METHOD FOR THE PRODUCTION THEREOF AND THEIR CONTAINING ANTIBACTERIAL AGENTS

Publications (1)

Publication Number Publication Date
PH18803A true PH18803A (en) 1985-09-27

Family

ID=6145081

Family Applications (1)

Application Number Title Priority Date Filing Date
PH28052A PH18803A (en) 1981-10-29 1982-10-28 1-cyclopropyl 6 fluoro 1,4 dihydro 4-oxo piperazino quinoline 3 carboxylic acids and antibacterial agent containing these compounds

Country Status (20)

Country Link
EP (1) EP0078362B1 (en)
JP (5) JPS5874667A (en)
KR (1) KR870000895B1 (en)
AT (1) ATE23040T1 (en)
AU (3) AU561103B2 (en)
CA (1) CA1218067A (en)
DD (1) DD202560A5 (en)
DE (2) DE3142854A1 (en)
DK (2) DK160491C (en)
ES (1) ES8307787A1 (en)
FI (1) FI78689C (en)
GR (1) GR77707B (en)
HU (1) HU187580B (en)
IE (1) IE53709B1 (en)
IL (1) IL66243A (en)
LU (1) LU88325I2 (en)
NO (2) NO158018C (en)
NZ (1) NZ202278A (en)
PH (1) PH18803A (en)
ZA (1) ZA824829B (en)

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Also Published As

Publication number Publication date
FI78689C (en) 1989-09-11
IE53709B1 (en) 1989-01-18
DK306082A (en) 1983-04-30
ATE23040T1 (en) 1986-11-15
DD202560A5 (en) 1983-09-21
JPS6322075A (en) 1988-01-29
ZA824829B (en) 1983-05-25
JPS6322076A (en) 1988-01-29
FI822442L (en) 1983-04-30
JPH0457674B2 (en) 1992-09-14
ES516921A0 (en) 1983-07-16
DK162637B (en) 1991-11-25
FI822442A0 (en) 1982-07-08
DK160491B (en) 1991-03-18
EP0078362A2 (en) 1983-05-11
NO822346L (en) 1983-05-02
AU573126B2 (en) 1988-05-26
AU561103B2 (en) 1987-04-30
AU8576882A (en) 1983-05-05
HU187580B (en) 1986-01-28
DK190890A (en) 1990-08-10
ES8307787A1 (en) 1983-07-16
NZ202278A (en) 1985-02-28
IL66243A (en) 1987-10-20
DK162637C (en) 1992-04-13
AU573125B2 (en) 1988-05-26
AU7140687A (en) 1987-07-30
JPH0824536B2 (en) 1996-03-13
DE3142854A1 (en) 1983-05-11
JPS5874667A (en) 1983-05-06
GR77707B (en) 1984-09-25
DK190890D0 (en) 1990-08-10
KR870000895B1 (en) 1987-05-02
IE821606L (en) 1983-04-29
JPS6362510B2 (en) 1988-12-02
JPH04253963A (en) 1992-09-09
DE3273892D1 (en) 1986-11-27
JPH0244827B2 (en) 1990-10-05
CA1218067A (en) 1987-02-17
NO158018C (en) 1988-06-29
KR840000525A (en) 1984-02-25
JPS6322057A (en) 1988-01-29
JPH0463067B2 (en) 1992-10-08
NO158018B (en) 1988-03-21
EP0078362A3 (en) 1984-08-22
FI78689B (en) 1989-05-31
DK160491C (en) 1991-08-26
NO1994030I1 (en) 1994-12-30
AU7140587A (en) 1987-08-06
EP0078362B1 (en) 1986-10-22
IL66243A0 (en) 1982-11-30
LU88325I2 (en) 1994-05-04

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