PH12974A - 6,7-benzomorphan derivatives and their pharmaceutical composition - Google Patents

6,7-benzomorphan derivatives and their pharmaceutical composition

Info

Publication number
PH12974A
PH12974A PH18131A PH18131A PH12974A PH 12974 A PH12974 A PH 12974A PH 18131 A PH18131 A PH 18131A PH 18131 A PH18131 A PH 18131A PH 12974 A PH12974 A PH 12974A
Authority
PH
Philippines
Prior art keywords
pharmaceutical composition
benzomorphan derivatives
benzomorphan
derivatives
pharmaceutical
Prior art date
Application number
PH18131A
Other languages
English (en)
Inventor
G Leeuwen
A Akkerman
Original Assignee
Acf Chemiefarma Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Acf Chemiefarma Nv filed Critical Acf Chemiefarma Nv
Publication of PH12974A publication Critical patent/PH12974A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/10—Oxygen atoms
    • C07D309/12—Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/22—Bridged ring systems
    • C07D221/26—Benzomorphans

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • One-Way And Automatic Clutches, And Combinations Of Different Clutches (AREA)
PH18131A 1975-02-25 1976-02-23 6,7-benzomorphan derivatives and their pharmaceutical composition PH12974A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB7891/75A GB1513961A (en) 1975-02-25 1975-02-25 6,7-benzomorphans method for their preparation and intermediates

Publications (1)

Publication Number Publication Date
PH12974A true PH12974A (en) 1979-10-24

Family

ID=9841801

Family Applications (1)

Application Number Title Priority Date Filing Date
PH18131A PH12974A (en) 1975-02-25 1976-02-23 6,7-benzomorphan derivatives and their pharmaceutical composition

Country Status (20)

Country Link
US (2) US4128548A (ja)
JP (2) JPS51111550A (ja)
AT (1) AT360663B (ja)
AU (1) AU505939B2 (ja)
BE (1) BE838708A (ja)
CA (1) CA1080704A (ja)
CH (2) CH621115A5 (ja)
DE (1) DE2606267A1 (ja)
DK (1) DK76176A (ja)
ES (1) ES445494A1 (ja)
FR (1) FR2302092A1 (ja)
GB (1) GB1513961A (ja)
HU (1) HU173571B (ja)
IE (1) IE43450B1 (ja)
IL (1) IL48990A (ja)
IT (1) IT1057250B (ja)
LU (1) LU74431A1 (ja)
NL (1) NL7601924A (ja)
PH (1) PH12974A (ja)
SE (1) SE7602235L (ja)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5381778A (en) * 1976-12-27 1978-07-19 Toshiharu Nakao Cloth loop forming apparatus in steaming apparatus
NL7804509A (nl) * 1978-04-26 1979-10-30 Acf Chemiefarma Nv Nieuwe 6,7-benzomorfanderivaten en zuuradditiezouten daarvan.
DE2828039A1 (de) * 1978-06-26 1980-01-10 Boehringer Sohn Ingelheim 2-(2-alkoxyethyl)-2'-hydroxy-6,7-benzomorphane deren saeureadditionssalze diese enthaltende arzneimittel und verfahren zu deren herstellung
US4208523A (en) * 1978-11-30 1980-06-17 Sterling Drug Inc. 11-Lower-alkyl-, 11-phenyl-lower-alkyl- and 11-cyclo-lower-alkyl-lower-alkyl-hexahydro-2,6-methano-3-benzazocines
NL7907800A (nl) * 1979-10-23 1981-04-27 Acf Chemiefarma Nv Nieuwe 6,7-benzomorfanderivaten en zuuradditiezouten daarvan, farmaceutische preparaten die een dergelijke verbinding bevatten, alsmede werkwijze voor het bereiden van deze verbindingen en de farmaceutische preparaten.
US5490436A (en) * 1994-03-17 1996-02-13 At&T Corp. Liquid-chamber apparatus for active, dynamic balancing of rotating machinery
US7501433B2 (en) * 2002-05-17 2009-03-10 Jenken Biosciences, Inc. Opioid and opioid-like compounds and uses thereof
US7923454B2 (en) * 2002-05-17 2011-04-12 Jenken Biosciences, Inc. Opioid and opioid-like compounds and uses thereof
EP2987788A1 (en) 2002-05-17 2016-02-24 Taiwanj Pharmaceuticals Co., Ltd. Opioid and opioid-like compounds and uses thereof
US8017622B2 (en) * 2003-05-16 2011-09-13 Jenken Biosciences, Inc. Opioid and opioid-like compounds and uses thereof
JP5470557B2 (ja) * 2007-07-26 2014-04-16 ヴァイティー ファーマシューティカルズ，インコーポレイテッド １１β−ヒドロキシステロイドデヒドロゲナーゼ１型の阻害剤の合成
AR069207A1 (es) * 2007-11-07 2010-01-06 Vitae Pharmaceuticals Inc Ureas ciclicas como inhibidores de la 11 beta - hidroxi-esteroide deshidrogenasa 1
CL2008003407A1 (es) * 2007-11-16 2010-01-11 Boehringer Ingelheim Int Compuestos derivados de aril- y heteroarilcarbonilo de heterobiciclo sustituido; composicion farmaceutica; procedimiento de preparacion; y su uso en el tratamiento y/o prevencion de trastornos metabolicos, mediado por la inhibicion de la enzima hsd-1.
JP5490014B2 (ja) 2007-12-11 2014-05-14 ヴァイティー ファーマシューティカルズ，インコーポレイテッド １１β−ヒドロキシステロイドデヒドロゲナーゼ１型の環状尿素阻害剤
TW200934490A (en) * 2008-01-07 2009-08-16 Vitae Pharmaceuticals Inc Lactam inhibitors of 11 &abgr;-hydroxysteroid dehydrogenase 1
US20110028445A1 (en) * 2008-02-12 2011-02-03 Boehringer Ingelheim International Gmbh Urea derivatives of benzomorphanes and related scaffolds, medicaments containing such compounds and their use
US8138178B2 (en) 2008-05-01 2012-03-20 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
AR071719A1 (es) 2008-05-13 2010-07-07 Boehringer Ingelheim Int Derivados aliciclicos de acido carboxilico de benzomorfanos y estructuras relacionadas, medicamentos que contienen dichos compuestos y su uso.procesos de obtencion
TW201016691A (en) 2008-07-25 2010-05-01 Boehringer Ingelheim Int Inhibitors of 11beta-hydroxysteroid dehydrogenase 1
NZ590495A (en) 2008-07-25 2012-10-26 Vitae Pharmaceuticals Inc Dihydropyridin-phenyl-3-oxazinan-2-ones as inhibitors of 11beta-hydroxysteroid dehydrogenase 1
US8680093B2 (en) 2009-04-30 2014-03-25 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
WO2010139673A1 (en) 2009-06-02 2010-12-09 Boehringer Ingelheim International Gmbh Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
US8927539B2 (en) 2009-06-11 2015-01-06 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11β-hydroxysteroid dehydrogenase 1 based on the 1,3-oxazinan-2-one structure
JP5456555B2 (ja) 2010-04-23 2014-04-02 株式会社マキタ 電動工具
US8933072B2 (en) 2010-06-16 2015-01-13 Vitae Pharmaceuticals, Inc. Substituted 5-,6- and 7-membered heterocycles, medicaments containing such compounds, and their use
WO2011161128A1 (en) 2010-06-25 2011-12-29 Boehringer Ingelheim International Gmbh Azaspirohexanones as inhibitors of 11-beta-hsd1 for the treatment of metabolic disorders
EA201300522A1 (ru) 2010-11-02 2013-11-29 Бёрингер Ингельхайм Интернациональ Гмбх Фармацевтические комбинации для лечения метаболических нарушений
WO2013025664A1 (en) 2011-08-17 2013-02-21 Boehringer Ingelheim International Gmbh Indenopyridine derivatives

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3138603A (en) * 1958-10-31 1964-06-23 Everette L May New benzomorphans (methanobenzazocines) and preparation thereof
US3372165A (en) * 1960-12-01 1968-03-05 Sterling Drug Inc 1, 2, 3, 4, 5, 6-hexahydro-8-hydroxy-2, 6-methano-3-benzazocine derivatives
IE34235B1 (en) * 1969-06-04 1975-03-19 Acf Chemiefarma Nv 6,7-benzomorphans and their preparation
NL156047B (nl) * 1969-06-04 1978-03-15 Acf Chemiefarma Nv Werkwijze voor de bereiding van farmaceutische preparaten met analgetische en/of morfine-antagonistische werking, gevormde preparaten, alsmede werkwijze voor de bereiding van daartoe geschikte nieuwe 6,7-benzomorfanen.
CA1010031A (en) * 1972-10-31 1977-05-10 Kentaro Tamaki 6,7-benzomorphan derivatives
US4010164A (en) * 1973-03-28 1977-03-01 Boehringer Ingelheim Gmbh N-(furyl-methyl)-2-hydroxy-5,9,9-trimethyl-benzomorphans and salts thereof
SU510999A3 (ru) * 1973-10-27 1976-04-15 К.Х.Берингер Зон, (Фирма) Способ получени (метоксиметил-фурилметил)6,7-бензоморфанов илиморфинанов
US4087532A (en) * 1974-03-09 1978-05-02 Boehringer Ingelheim Gmbh Analgesically useful 2-tetrahydrofurfuryl-5-lower alkyl-2-oxy-6,7-benzomorphans and salts thereof
US4032529A (en) * 1974-09-20 1977-06-28 Sterling Drug Inc. Aminomethanobenzazocine intermediates

Also Published As

Publication number Publication date
BE838708A (fr) 1976-08-19
AT360663B (de) 1981-01-26
AU1085676A (en) 1977-08-11
NL7601924A (nl) 1976-08-27
IE43450B1 (en) 1981-02-25
CH623572A5 (ja) 1981-06-15
US4268673A (en) 1981-05-19
LU74431A1 (ja) 1976-08-13
ATA137276A (de) 1980-06-15
AU505939B2 (en) 1979-12-06
GB1513961A (en) 1978-06-14
DE2606267A1 (de) 1976-09-30
JPS51118767A (en) 1976-10-18
FR2302092A1 (fr) 1976-09-24
HU173571B (hu) 1979-06-28
ES445494A1 (es) 1977-11-01
DK76176A (da) 1976-08-26
JPS51111550A (en) 1976-10-01
CA1080704A (en) 1980-07-01
SE7602235L (sv) 1976-08-26
IE43450L (en) 1976-08-25
US4128548A (en) 1978-12-05
CH621115A5 (ja) 1981-01-15
FR2302092B1 (ja) 1978-11-10
IL48990A0 (en) 1976-04-30
IL48990A (en) 1980-01-31
IT1057250B (it) 1982-03-10

Similar Documents

Publication Publication Date Title
PH12974A (en) 6,7-benzomorphan derivatives and their pharmaceutical composition
GB1552911A (en) 1,4 dihydropyridine derivatives and the preparation thereof
NZ181444A (en) -phenyl benzylidene derivatives and pharmaceutical compositions
NZ180529A (en) Erythromyc-9-yl-amine derivatives and pharmaceutical compositions
IL49911A0 (en) New 5-aroylpyrrole derivatives,their preparation and pharmaceutical compositions containing them
GB1520447A (en) Benzisoquinoline derivatives and pharmaceutical uses thereof
NZ179835A (en) Aminoalkynoic acids,derivatives and pharmaceutical compositions
PH13918A (en) Benzisothiazolone,antithrombotics and their pharmaceutical composition
IL50869A (en) Heterocyclylthio-ethylimidazole derivatives,their preparation and pharmaceutical compositions containing them
NZ182555A (en) Spiro(1,3-dioxalane-4,3)-quinuclidine derivatives and pharmaceutical compositions
IL49424A0 (en) 1,1,1-triaryl-alkylamines,their preparation and pharmaceutical compositions containing them
NZ180379A (en) Benzophenone derivatives and pharmaceutical composition
NZ181503A (en) Substituted diphenyls-ulphides and pharmaceutical compositions
NZ182591A (en) 14-substituted-daunorubicins and pharmaceutical compositions
NZ182161A (en) Alkoxy-pyridine-carobxamide derivatives and pharmaceutical compositions
IL50335A (en) Diphenylalkylpolyamine derivatives,their preparation and pharmaceutical compositions containing them
NZ181972A (en) N-aryl-n-(4-piperidyl)-arylacetamide derivatives and pharmaceutical compositions
NZ182581A (en) -amino-ketones and pharmaceutical compositions
NZ181864A (en) Noroxymorphones and pharmaceutical compositions
IL58505A0 (en) 16,16-disubstituted androst-5-ene derivatives and their preparation
NZ182502A (en) 1,4-dihydro-2,6-dimethyl-3-methoxycarbonyl-5-isobut-oxycarbonyl-4-(21-nitrophenyl)-pyridine and pharmaceutical compositions
IL50156A0 (en) New homophthalimide derivatives,their preparation and pharmaceutical compositions containing them
NZ181727A (en) Pyrroline-2-one derivatives and pharmaceutical compositions
NZ181401A (en) 2-benzopyranone derivatives and pharmaceutical compositions
NZ180657A (en) 3-aminoalkyl-2-phenyl-bicyclo (2.2.2)-octane or-oct-2-ene derivatives,and pharmaceutical compositions