PH12022552118A1 - Group a strep immunogenic compositions with polysaccharide-protein conjugates - Google Patents

Group a strep immunogenic compositions with polysaccharide-protein conjugates

Info

Publication number
PH12022552118A1
PH12022552118A1 PH1/2022/552118A PH12022552118A PH12022552118A1 PH 12022552118 A1 PH12022552118 A1 PH 12022552118A1 PH 12022552118 A PH12022552118 A PH 12022552118A PH 12022552118 A1 PH12022552118 A1 PH 12022552118A1
Authority
PH
Philippines
Prior art keywords
group
polysaccharide
immunogenic compositions
strep
protein conjugates
Prior art date
Application number
PH1/2022/552118A
Other languages
English (en)
Inventor
Peter T Davey
Jeffery C Fairman
Neeraj Kapoor
Angie A Sedra
Original Assignee
Vaxcyte Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vaxcyte Inc filed Critical Vaxcyte Inc
Publication of PH12022552118A1 publication Critical patent/PH12022552118A1/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46Hydrolases (3)
    • A61K38/48Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/482Serine endopeptidases (3.4.21)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/025Enterobacteriales, e.g. Enterobacter
    • A61K39/0283Shigella
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/09Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
    • A61K39/092Streptococcus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/116Polyvalent bacterial antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y304/00Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21Serine endopeptidases (3.4.21)
    • C12Y304/2111C5a peptidase (3.4.21.110)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/58Medicinal preparations containing antigens or antibodies raising an immune response against a target which is not the antigen used for immunisation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/60Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6087Polysaccharides; Lipopolysaccharides [LPS]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/70Multivalent vaccine
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
PH1/2022/552118A 2020-02-18 2021-02-17 Group a strep immunogenic compositions with polysaccharide-protein conjugates PH12022552118A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US202062977886P 2020-02-18 2020-02-18
US202063013924P 2020-04-22 2020-04-22
US202063090069P 2020-10-09 2020-10-09
US202063123293P 2020-12-09 2020-12-09
PCT/US2021/018402 WO2021167996A1 (en) 2020-02-18 2021-02-17 Group a strep immunogenic compositions with polysaccharide-protein conjugates

Publications (1)

Publication Number Publication Date
PH12022552118A1 true PH12022552118A1 (en) 2024-01-29

Family

ID=74860575

Family Applications (1)

Application Number Title Priority Date Filing Date
PH1/2022/552118A PH12022552118A1 (en) 2020-02-18 2021-02-17 Group a strep immunogenic compositions with polysaccharide-protein conjugates

Country Status (13)

Country Link
US (1) US20230293658A1 (enExample)
EP (1) EP4106807A1 (enExample)
JP (1) JP2023514332A (enExample)
KR (1) KR20220143107A (enExample)
CN (1) CN115175697A (enExample)
AU (1) AU2021224585A1 (enExample)
BR (1) BR112022016268A2 (enExample)
CA (1) CA3168201A1 (enExample)
IL (1) IL295702A (enExample)
MX (1) MX2022010129A (enExample)
PH (1) PH12022552118A1 (enExample)
TW (1) TW202136285A (enExample)
WO (1) WO2021167996A1 (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20230052958A (ko) 2020-08-19 2023-04-20 박사이트, 인코포레이티드 운반-단백질 폴리삭카라이드 접합 방법
EP4294452A4 (en) * 2021-02-17 2025-09-24 Vaxcyte Inc METHODS FOR PURIFYING POLYSACCHARIDES AND CORRESPONDING POLYPEPTIDE CONJUGATES

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6355255B1 (en) * 1998-12-07 2002-03-12 Regents Of The University Of Minnesota Streptococcal C5a peptidase vaccine
BRPI0821240B8 (pt) * 2007-12-21 2022-10-04 Novartis Ag formas mutantes de estreptolisina o
CN102264444B (zh) 2008-10-27 2015-08-05 诺华股份有限公司 纯化方法
US20140294930A1 (en) 2011-08-04 2014-10-02 The Regents Of The University Of California STREPTOCOCCAL GlcNAc-LACKING GLYCOPOLYPEPTIDES, CELL WALL CARBOHYDRATES, STREPTOCOCCUS VACCINES, AND METHODS FOR MAKING AND USING THEM
RU2662970C2 (ru) * 2012-09-18 2018-07-31 Новартис Аг Везикулы наружной мембраны
MX2019007910A (es) 2016-12-30 2019-12-05 Sutrovax Inc Conjugados de polipeptido-antigeno con aminoacidos no naturales.

Also Published As

Publication number Publication date
AU2021224585A1 (en) 2022-10-13
WO2021167996A1 (en) 2021-08-26
TW202136285A (zh) 2021-10-01
JP2023514332A (ja) 2023-04-05
BR112022016268A2 (pt) 2022-10-11
CN115175697A (zh) 2022-10-11
EP4106807A1 (en) 2022-12-28
CA3168201A1 (en) 2021-08-26
KR20220143107A (ko) 2022-10-24
MX2022010129A (es) 2022-09-05
US20230293658A1 (en) 2023-09-21
IL295702A (en) 2022-10-01

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