MX2022010129A - Composiciones inmunogenicas de streptococo del grupo a con conjugados de proteina de polisacaridos. - Google Patents

Composiciones inmunogenicas de streptococo del grupo a con conjugados de proteina de polisacaridos.

Info

Publication number
MX2022010129A
MX2022010129A MX2022010129A MX2022010129A MX2022010129A MX 2022010129 A MX2022010129 A MX 2022010129A MX 2022010129 A MX2022010129 A MX 2022010129A MX 2022010129 A MX2022010129 A MX 2022010129A MX 2022010129 A MX2022010129 A MX 2022010129A
Authority
MX
Mexico
Prior art keywords
group
immunogenic compositions
polysaccharide
protei
strep
Prior art date
Application number
MX2022010129A
Other languages
English (en)
Inventor
Neeraj Kapoor
Jeffery C Fairman
Peter T Davey
Angie A Sedra
Original Assignee
Vaxcyte Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vaxcyte Inc filed Critical Vaxcyte Inc
Publication of MX2022010129A publication Critical patent/MX2022010129A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
    • A61K39/092—Streptococcus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/025—Enterobacteriales, e.g. Enterobacter
    • A61K39/0283—Shigella
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/482—Serine endopeptidases (3.4.21)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/2111—C5a peptidase (3.4.21.110)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/58—Medicinal preparations containing antigens or antibodies raising an immune response against a target which is not the antigen used for immunisation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6087—Polysaccharides; Lipopolysaccharides [LPS]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/70—Multivalent vaccine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/116—Polyvalent bacterial antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)

Abstract

La presente descripción proporciona composiciones inmunogénicas que comprenden antígenos polipeptídicos de Streptococcus del grupo A (GAS) y al menos un conjugado de polipéptido-polisacárido; la presente descripción proporciona además métodos para usar dichas composiciones para inducir respuestas inmunitarias contra infecciones por GAS en sujetos.
MX2022010129A 2020-02-18 2021-02-17 Composiciones inmunogenicas de streptococo del grupo a con conjugados de proteina de polisacaridos. MX2022010129A (es)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US202062977886P 2020-02-18 2020-02-18
US202063013924P 2020-04-22 2020-04-22
US202063090069P 2020-10-09 2020-10-09
US202063123293P 2020-12-09 2020-12-09
PCT/US2021/018402 WO2021167996A1 (en) 2020-02-18 2021-02-17 Group a strep immunogenic compositions with polysaccharide-protein conjugates

Publications (1)

Publication Number Publication Date
MX2022010129A true MX2022010129A (es) 2022-09-05

Family

ID=74860575

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2022010129A MX2022010129A (es) 2020-02-18 2021-02-17 Composiciones inmunogenicas de streptococo del grupo a con conjugados de proteina de polisacaridos.

Country Status (12)

Country Link
US (1) US20230293658A1 (es)
EP (1) EP4106807A1 (es)
JP (1) JP2023514332A (es)
KR (1) KR20220143107A (es)
CN (1) CN115175697A (es)
AU (1) AU2021224585A1 (es)
BR (1) BR112022016268A2 (es)
CA (1) CA3168201A1 (es)
IL (1) IL295702A (es)
MX (1) MX2022010129A (es)
TW (1) TW202136285A (es)
WO (1) WO2021167996A1 (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW202227127A (zh) * 2020-08-19 2022-07-16 美商Ｖａｘｃｙｔｅ公司 載體-蛋白多醣之結合方法
IL305201A (en) * 2021-02-17 2023-10-01 Vaxcyte Inc Methods for the distillation of polysaccharides and their polypeptide conjugates

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2777837C (en) 2008-10-27 2017-07-11 Novartis Ag Purification method
US20140294930A1 (en) 2011-08-04 2014-10-02 The Regents Of The University Of California STREPTOCOCCAL GlcNAc-LACKING GLYCOPOLYPEPTIDES, CELL WALL CARBOHYDRATES, STREPTOCOCCUS VACCINES, AND METHODS FOR MAKING AND USING THEM
CA3048981A1 (en) 2016-12-30 2018-07-05 Sutrovax, Inc. Polypeptide-antigen conjugates with non-natural amino acids

Also Published As

Publication number Publication date
CN115175697A (zh) 2022-10-11
KR20220143107A (ko) 2022-10-24
JP2023514332A (ja) 2023-04-05
CA3168201A1 (en) 2021-08-26
TW202136285A (zh) 2021-10-01
AU2021224585A1 (en) 2022-10-13
BR112022016268A2 (pt) 2022-10-11
US20230293658A1 (en) 2023-09-21
EP4106807A1 (en) 2022-12-28
WO2021167996A1 (en) 2021-08-26
IL295702A (en) 2022-10-01

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