PH12021551047A1 - Anti-ptk7 immune cell cancer therapy - Google Patents

Anti-ptk7 immune cell cancer therapy

Info

Publication number
PH12021551047A1
PH12021551047A1 PH12021551047A PH12021551047A PH12021551047A1 PH 12021551047 A1 PH12021551047 A1 PH 12021551047A1 PH 12021551047 A PH12021551047 A PH 12021551047A PH 12021551047 A PH12021551047 A PH 12021551047A PH 12021551047 A1 PH12021551047 A1 PH 12021551047A1
Authority
PH
Philippines
Prior art keywords
ptk7
cancer therapy
immune cell
cell cancer
compositions
Prior art date
Application number
PH12021551047A
Other languages
English (en)
Inventor
Jonathan Alexander Terrett
Jason Sagert
Original Assignee
Crispr Therapeutics Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Crispr Therapeutics Ag filed Critical Crispr Therapeutics Ag
Publication of PH12021551047A1 publication Critical patent/PH12021551047A1/en

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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0636—T lymphocytes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/70521—CD28, CD152
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/17—Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytes
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/10—Cellular immunotherapy characterised by the cell type used
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K40/30—Cellular immunotherapy characterised by the recombinant expression of specific molecules in the cells of the immune system
    • A61K40/31—Chimeric antigen receptors [CAR]
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    • A61K40/41—Vertebrate antigens
    • A61K40/42—Cancer antigens
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    • A61K40/4251—Kinases, e.g. Raf or Src
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
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    • C—CHEMISTRY; METALLURGY
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    • C—CHEMISTRY; METALLURGY
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    • C—CHEMISTRY; METALLURGY
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    • C07K—PEPTIDES
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    • C07K16/40—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against enzymes
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
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    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K2039/80—Vaccine for a specifically defined cancer
    • A61K2039/852—Pancreas
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    • A—HUMAN NECESSITIES
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    • A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K40/00
    • A61K2239/38—Indexing codes associated with cellular immunotherapy of group A61K40/00 characterised by the dose, timing or administration schedule
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    • A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K40/00
    • A61K2239/46—Indexing codes associated with cellular immunotherapy of group A61K40/00 characterised by the cancer treated
    • A61K2239/54—Pancreas
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A—HUMAN NECESSITIES
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    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
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    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
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    • C07K2317/00—Immunoglobulins specific features
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    • C07K2317/565—Complementarity determining region [CDR]
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    • C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
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    • C12N2750/14011—Parvoviridae
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    • C12N2750/14141—Use of virus, viral particle or viral elements as a vector
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  • Proteomics, Peptides & Aminoacids (AREA)
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Virology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
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PH12021551047A 2018-11-07 2021-05-06 Anti-ptk7 immune cell cancer therapy PH12021551047A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862756638P 2018-11-07 2018-11-07
US201962910586P 2019-10-04 2019-10-04
PCT/IB2019/059585 WO2020095248A1 (en) 2018-11-07 2019-11-07 Anti-ptk7 immune cell cancer therapy

Publications (1)

Publication Number Publication Date
PH12021551047A1 true PH12021551047A1 (en) 2021-12-13

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PH12021551047A PH12021551047A1 (en) 2018-11-07 2021-05-06 Anti-ptk7 immune cell cancer therapy

Country Status (15)

Country Link
US (3) US12146157B2 (OSRAM)
EP (1) EP3877421A1 (OSRAM)
JP (2) JP2022509017A (OSRAM)
KR (1) KR20210092236A (OSRAM)
CN (1) CN112955472A (OSRAM)
AU (1) AU2019374523A1 (OSRAM)
BR (1) BR112021008083A2 (OSRAM)
CA (1) CA3118830A1 (OSRAM)
CO (1) CO2021005471A2 (OSRAM)
IL (1) IL282532A (OSRAM)
MX (1) MX2021005400A (OSRAM)
PH (1) PH12021551047A1 (OSRAM)
SG (1) SG11202104631SA (OSRAM)
WO (1) WO2020095248A1 (OSRAM)
ZA (1) ZA202102745B (OSRAM)

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JP2026510870A (ja) * 2023-03-22 2026-04-10 アジレント・テクノロジーズ・インク 免疫組織化学的（ｉｈｃ）ｐｔｋ７スコア化プロトコル及び癌処置を補助する方法
CN117085134A (zh) * 2023-07-19 2023-11-21 浙江大学 Ptk7抑制剂在制备预防或治疗肝癌的药物中的用途
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WO2020095248A1 (en) 2020-05-14
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SG11202104631SA (en) 2021-06-29
US20200140815A1 (en) 2020-05-07
KR20210092236A (ko) 2021-07-23
US12146157B2 (en) 2024-11-19
IL282532A (en) 2021-06-30
EP3877421A1 (en) 2021-09-15
ZA202102745B (en) 2022-10-26
CN112955472A (zh) 2021-06-11
CA3118830A1 (en) 2020-05-14
BR112021008083A2 (pt) 2021-08-10
US20250074965A1 (en) 2025-03-06
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MX2021005400A (es) 2021-07-06
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