PH12016500749A1 - A method for preparing an intermediate of iopromide - Google Patents

A method for preparing an intermediate of iopromide

Info

Publication number
PH12016500749A1
PH12016500749A1 PH12016500749A PH12016500749A PH12016500749A1 PH 12016500749 A1 PH12016500749 A1 PH 12016500749A1 PH 12016500749 A PH12016500749 A PH 12016500749A PH 12016500749 A PH12016500749 A PH 12016500749A PH 12016500749 A1 PH12016500749 A1 PH 12016500749A1
Authority
PH
Philippines
Prior art keywords
iopromide
preparing
solvent
dioxane
reaction
Prior art date
Application number
PH12016500749A
Other languages
English (en)
Other versions
PH12016500749B1 (en
Inventor
Jin Yong Suk
Kim Wol Young
Lee Joon Hwan
Kim Seung Tae
Kim Sang Hyun
Yoon Hee Kyoon
Original Assignee
Daewong Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Daewong Pharmaceutical Co Ltd filed Critical Daewong Pharmaceutical Co Ltd
Publication of PH12016500749B1 publication Critical patent/PH12016500749B1/en
Publication of PH12016500749A1 publication Critical patent/PH12016500749A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/02—Preparation of carboxylic acid amides from carboxylic acids or from esters, anhydrides, or halides thereof by reaction with ammonia or amines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B43/00—Formation or introduction of functional groups containing nitrogen
    • C07B43/06—Formation or introduction of functional groups containing nitrogen of amide groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/12—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by halogen atoms or by nitro or nitroso groups
    • C07C233/15—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by halogen atoms or by nitro or nitroso groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
PH12016500749A 2013-10-25 2016-04-21 A method for preparing an intermediate of iopromide PH12016500749A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR1020130128154A KR101520187B1 (ko) 2013-10-25 2013-10-25 이오프로마이드의 중간체의 제조방법
PCT/KR2014/009991 WO2015060657A1 (en) 2013-10-25 2014-10-23 A method for preparing an intermediate of iopromide

Publications (2)

Publication Number Publication Date
PH12016500749B1 PH12016500749B1 (en) 2016-06-13
PH12016500749A1 true PH12016500749A1 (en) 2016-06-13

Family

ID=52993179

Family Applications (1)

Application Number Title Priority Date Filing Date
PH12016500749A PH12016500749A1 (en) 2013-10-25 2016-04-21 A method for preparing an intermediate of iopromide

Country Status (7)

Country Link
KR (1) KR101520187B1 (zh)
CN (1) CN105636933B (zh)
EA (1) EA031801B1 (zh)
PH (1) PH12016500749A1 (zh)
SA (1) SA516370977B1 (zh)
UA (1) UA114158C2 (zh)
WO (1) WO2015060657A1 (zh)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110078636B (zh) * 2019-05-23 2022-05-17 浙江海洲制药有限公司 一种制备碘普罗胺中间体的方法
CN114436880B (zh) * 2020-11-03 2023-04-28 成都倍特药业股份有限公司 碘普罗胺中间体的制备方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2909439A1 (de) * 1979-03-08 1980-09-18 Schering Ag Neue nichtionische roentgenkontrastmittel
DE3429949A1 (de) * 1984-08-10 1986-02-20 Schering AG, 1000 Berlin und 4709 Bergkamen Neue nicht -ionische 2,4,6-trijod-isophthalsaeure-bis-amide, verfahren zu ihrer herstellung und ihre verwendung als roentgenkontrastmittel
AU5093993A (en) * 1992-09-02 1994-03-29 Mallinckrodt Medical, Inc. Nonionic X-ray contrast agents compositions and methods
IT1286522B1 (it) 1996-12-04 1998-07-15 Dibra Spa Processo per la preparazione di derivati dell'acido 5-ammino-2,4,6- triiodo-1,3-benzenedicarbossilico
IT1292037B1 (it) 1997-05-30 1999-01-25 Bracco Spa Processo per la preparazione di 5-(acetil 62,3-diidrossipropil)- ammino)-n,n'-bis(2,3-diidrossipropil)-2,4,6-triiodo-1,3-benzen-
KR100286639B1 (ko) * 1999-03-31 2001-04-16 강재헌 이오프로마이드의 제조방법
EP2231200A1 (en) * 2007-12-05 2010-09-29 GE Healthcare AS Contrast agents
KR101098553B1 (ko) * 2008-04-30 2011-12-26 주식회사 엘지생명과학 이오프로마이드의 신규한 제조방법

Also Published As

Publication number Publication date
PH12016500749B1 (en) 2016-06-13
KR101520187B1 (ko) 2015-05-13
EA201690757A1 (ru) 2016-10-31
EA031801B1 (ru) 2019-02-28
CN105636933A (zh) 2016-06-01
SA516370977B1 (ar) 2017-08-21
CN105636933B (zh) 2017-12-15
KR20150047997A (ko) 2015-05-06
UA114158C2 (uk) 2017-04-25
WO2015060657A1 (en) 2015-04-30

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