PE20230495A1 - Vacunacion con el dominio alfa 3 de mica/b para el tratamiento del cancer - Google Patents

Vacunacion con el dominio alfa 3 de mica/b para el tratamiento del cancer

Info

Publication number
PE20230495A1
PE20230495A1 PE2022002801A PE2022002801A PE20230495A1 PE 20230495 A1 PE20230495 A1 PE 20230495A1 PE 2022002801 A PE2022002801 A PE 2022002801A PE 2022002801 A PE2022002801 A PE 2022002801A PE 20230495 A1 PE20230495 A1 PE 20230495A1
Authority
PE
Peru
Prior art keywords
alpha
domain
cancer
vaccination
mica
Prior art date
Application number
PE2022002801A
Other languages
English (en)
Spanish (es)
Inventor
Kai Wucherpfennig
Soumya Badrinath
Original Assignee
Dana Farber Cancer Inst Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dana Farber Cancer Inst Inc filed Critical Dana Farber Cancer Inst Inc
Publication of PE20230495A1 publication Critical patent/PE20230495A1/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/74Bacteria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/0005Vertebrate antigens
    • A61K39/0011Cancer antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/0005Vertebrate antigens
    • A61K39/0011Cancer antigens
    • A61K39/001136Cytokines
    • A61K39/001139Colony stimulating factors [CSF]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/105Delta proteobacteriales, e.g. Lawsonia; Epsilon proteobacteriales, e.g. campylobacter, helicobacter
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/205Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Campylobacter (G)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55522Cytokines; Lymphokines; Interferons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55555Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55561CpG containing adjuvants; Oligonucleotide containing adjuvants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/60Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031Proteins
    • A61K2039/6068Other bacterial proteins, e.g. OMP
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/64Medicinal preparations containing antigens or antibodies characterised by the architecture of the carrier-antigen complex, e.g. repetition of carrier-antigen units
    • A61K2039/645Dendrimers; Multiple antigen peptides
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Oncology (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
PE2022002801A 2015-12-04 2016-12-05 Vacunacion con el dominio alfa 3 de mica/b para el tratamiento del cancer PE20230495A1 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562263377P 2015-12-04 2015-12-04
US201662422454P 2016-11-15 2016-11-15
PCT/US2016/064969 WO2017096374A1 (fr) 2015-12-04 2016-12-05 Vaccination avec le domaine alpha 3 mica/b pour le traitement du cancer

Publications (1)

Publication Number Publication Date
PE20230495A1 true PE20230495A1 (es) 2023-03-23

Family

ID=57590885

Family Applications (2)

Application Number Title Priority Date Filing Date
PE2022002801A PE20230495A1 (es) 2015-12-04 2016-12-05 Vacunacion con el dominio alfa 3 de mica/b para el tratamiento del cancer
PE2018001072A PE20181158A1 (es) 2015-12-04 2016-12-05 Vacunacion con el dominio alfa 3 de mica/b para el tratamiento del cancer

Family Applications After (1)

Application Number Title Priority Date Filing Date
PE2018001072A PE20181158A1 (es) 2015-12-04 2016-12-05 Vacunacion con el dominio alfa 3 de mica/b para el tratamiento del cancer

Country Status (24)

Country Link
US (2) US10993971B2 (fr)
EP (1) EP3383426A1 (fr)
JP (2) JP7099956B2 (fr)
KR (1) KR20180088458A (fr)
CN (1) CN108770343A (fr)
AU (2) AU2016362597C1 (fr)
BR (1) BR112018010705A8 (fr)
CA (1) CA3005910A1 (fr)
CL (2) CL2018001470A1 (fr)
CO (1) CO2018006642A2 (fr)
CR (2) CR20230116A (fr)
CU (2) CU20210061A7 (fr)
EA (1) EA201891287A1 (fr)
IL (1) IL259490A (fr)
MX (2) MX2018006785A (fr)
MY (1) MY199248A (fr)
NZ (1) NZ742663A (fr)
PE (2) PE20230495A1 (fr)
PH (1) PH12018501170A1 (fr)
RU (2) RU2021109510A (fr)
SG (1) SG11201804597TA (fr)
TN (1) TN2018000187A1 (fr)
WO (1) WO2017096374A1 (fr)
ZA (1) ZA202204223B (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2021519599A (ja) 2018-04-03 2021-08-12 サノフイSanofi 抗原性ospaポリペプチド
EP3773698A1 (fr) 2018-04-03 2021-02-17 Sanofi Protéines de ferritine
CN116396398A (zh) * 2023-01-16 2023-07-07 四川大学 一种实现铁蛋白纳米颗粒可控自组装的方法以及基于该方法搭建的纳米颗粒抗原展示平台

Family Cites Families (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4709017A (en) 1985-06-07 1987-11-24 President And Fellows Of Harvard College Modified toxic vaccines
US4950740A (en) 1987-03-17 1990-08-21 Cetus Corporation Recombinant diphtheria vaccines
DE3841091A1 (de) 1988-12-07 1990-06-13 Behringwerke Ag Synthetische antigene, verfahren zu ihrer herstellung und ihre verwendung
DE68907045T2 (de) 1989-01-17 1993-12-02 Eniricerche Spa Synthetische Peptide und deren Verwendung als allgemeine Träger für die Herstellung von immunogenischen Konjugaten, die für die Entwicklung von synthetischen Impfstoffen geeignet sind.
CA2063271A1 (fr) 1989-07-14 1991-01-15 Subramonia Pillai Vecteurs de cytokine et d'hormones pour vaccins conjugues
US5073627A (en) 1989-08-22 1991-12-17 Immunex Corporation Fusion proteins comprising GM-CSF and IL-3
IT1237764B (it) 1989-11-10 1993-06-17 Eniricerche Spa Peptidi sintetici utili come carriers universali per la preparazione di coniugati immunogenici e loro impiego per lo sviluppo di vaccini sintetici.
SE466259B (sv) 1990-05-31 1992-01-20 Arne Forsgren Protein d - ett igd-bindande protein fraan haemophilus influenzae, samt anvaendning av detta foer analys, vacciner och uppreningsaendamaal
DE69113564T2 (de) 1990-08-13 1996-05-30 American Cyanamid Co Faser-Hemagglutinin von Bordetella pertussis als Träger für konjugierten Impfstoff.
IT1262896B (it) 1992-03-06 1996-07-22 Composti coniugati formati da proteine heat shock (hsp) e oligo-poli- saccaridi, loro uso per la produzione di vaccini.
DE69324487T2 (de) 1992-05-06 1999-08-12 Harvard College Rezeptorbindende region des diphtherietoxius
IL102687A (en) 1992-07-30 1997-06-10 Yeda Res & Dev Conjugates of poorly immunogenic antigens and synthetic pepide carriers and vaccines comprising them
US5917017A (en) 1994-06-08 1999-06-29 President And Fellows Of Harvard College Diphtheria toxin vaccines bearing a mutated R domain
US6455673B1 (en) 1994-06-08 2002-09-24 President And Fellows Of Harvard College Multi-mutant diphtheria toxin vaccines
WO1998018931A2 (fr) 1996-10-31 1998-05-07 Human Genome Sciences, Inc. Polynucleotides et sequences de streptococcus pneumoniae
GB9713156D0 (en) 1997-06-20 1997-08-27 Microbiological Res Authority Vaccines
JP4846906B2 (ja) 1999-03-19 2011-12-28 グラクソスミスクライン バイオロジカルズ ソシエテ アノニム ワクチン
CA2365914A1 (fr) 1999-04-09 2000-10-19 Techlab, Inc. Support proteique recombinant de la toxine a du clostridium recombinant pour vaccins conjugues polysaccharides
GB0007432D0 (en) 2000-03-27 2000-05-17 Microbiological Res Authority Proteins for use as carriers in conjugate vaccines
AU2002309706A1 (en) 2001-05-11 2002-11-25 Aventis Pasteur, Inc. Novel meningitis conjugate vaccine
DE60226911D1 (de) 2001-10-01 2008-07-10 Us Health Entwicklung einer Vakzine zur Prävention von Infektionen mit Filovirus bei Primaten
US6706305B2 (en) 2001-10-31 2004-03-16 Conagra Foods Inc. Low glycemic index bread
ATE453669T1 (de) * 2002-05-10 2010-01-15 New Century Pharmaceuticals Ferritinfusionsproteine zur verwendung für impfstoffe und andere anwendungen
EP1809738B1 (fr) 2004-11-02 2014-03-05 THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by the Secretary, Department of Health and Human Services Compositions et procedes pour traiter des etats hyperproliferatifs
GB0428394D0 (en) 2004-12-24 2005-02-02 Chiron Srl Saccharide conjugate vaccines
US8110196B2 (en) 2005-04-29 2012-02-07 Polytopas LLC Methods and compositions for polytopic vaccination
US20070104689A1 (en) * 2005-09-27 2007-05-10 Merck Patent Gmbh Compositions and methods for treating tumors presenting survivin antigens
WO2008036981A1 (fr) 2006-09-22 2008-03-27 Dana-Farber Cancer Research, Inc. Procédés pour traiter des troubles en rapport avec le mica
WO2011046842A1 (fr) 2009-10-12 2011-04-21 The Regents Of The University Of California Nano-amas ciblés et méthodes d'utilisation
US8889044B2 (en) 2009-12-18 2014-11-18 Kao Corporation Method for producing mesoporous silica particles
JP5603063B2 (ja) 2009-12-21 2014-10-08 花王株式会社 複合シリカ粒子の製造方法
RU2489169C2 (ru) * 2010-10-12 2013-08-10 Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Новосибирский национальный исследовательский государственный университет" (Новосибирский государственный университет, НГУ) Способ лечения онкологических заболеваний
CN104136039A (zh) * 2011-09-23 2014-11-05 奥斯陆大学 靶向交叉呈递的树突状细胞的疫苗体
NZ721184A (en) 2011-09-30 2018-08-31 Dana Farber Cancer Inst Inc Therapeutic peptides
JP6405242B2 (ja) * 2012-02-07 2018-10-17 イナート・ファルマ・ソシエテ・アノニムInnate Pharma Pharma S.A. Mica結合剤
LT2838515T (lt) 2012-04-16 2020-03-10 President And Fellows Of Harvard College Mezoporinės silico dioksido kompozicijos, skirtos imuninio atsako moduliavimui
EP2970490A4 (fr) * 2013-03-15 2017-04-26 Novelogics Biotechnology, Inc. Anticorps pour protéines mica et micb
EA201591559A1 (ru) 2013-03-15 2016-03-31 Дана-Фарбер Кэнсер Инститьют, Инк. Терапевтические пептиды
EP3116903A2 (fr) * 2014-03-14 2017-01-18 Dana-Farber Cancer Institute, Inc. Compositions vaccinales et méthodes pour rétablir la fonction de la voie nkg2d contre les cancers

Also Published As

Publication number Publication date
RU2018123307A3 (fr) 2020-04-20
US20180353581A1 (en) 2018-12-13
KR20180088458A (ko) 2018-08-03
BR112018010705A8 (pt) 2019-02-26
AU2022201940A1 (en) 2022-04-14
CR20180350A (es) 2018-10-02
EA201891287A1 (ru) 2018-11-30
TN2018000187A1 (en) 2019-10-04
MX2018006785A (es) 2018-11-09
JP2022130623A (ja) 2022-09-06
AU2016362597B2 (en) 2022-02-17
CU24609B1 (es) 2022-06-06
US10993971B2 (en) 2021-05-04
CL2021001256A1 (es) 2021-12-31
PH12018501170A1 (en) 2019-01-21
JP2018536002A (ja) 2018-12-06
RU2021109510A (ru) 2021-04-16
RU2747296C2 (ru) 2021-05-04
CA3005910A1 (fr) 2017-06-08
MX2022010194A (es) 2022-09-19
AU2016362597A1 (en) 2018-06-07
IL259490A (en) 2018-07-31
MY199248A (en) 2023-10-23
WO2017096374A1 (fr) 2017-06-08
SG11201804597TA (en) 2018-06-28
AU2016362597C1 (en) 2022-05-26
RU2018123307A (ru) 2020-01-13
CR20230116A (es) 2023-05-05
CO2018006642A2 (es) 2018-07-10
JP7099956B2 (ja) 2022-07-12
US20210299186A1 (en) 2021-09-30
CU20180050A7 (es) 2018-11-06
CL2018001470A1 (es) 2018-12-21
PE20181158A1 (es) 2018-07-19
EP3383426A1 (fr) 2018-10-10
ZA202204223B (en) 2023-12-20
CU20210061A7 (es) 2022-02-04
BR112018010705A2 (pt) 2018-11-21
NZ742663A (en) 2023-02-24
CN108770343A (zh) 2018-11-06

Similar Documents

Publication Publication Date Title
CL2018001358A1 (es) Composiciones que comprenden cepas bacterianas
CY1122329T1 (el) Anti-siglec-8 αντισωματα και μeθοδοι χρhσεως αυτων
MD3209381T2 (ro) Compoziții care conțin tulpini bacteriene
MX2021013837A (es) Enfoque de inmunoterapias de combinacion para el tratamiento del cancer.
PE20180673A1 (es) Tratamiento contra el cancer por manipulacion de la microflora comensal
MD4733C1 (ro) Anticorpi anti-TIGIT
MX2017001406A (es) Agentes a base de flagelina y usos de los mismos, incluyendo vacunación efectiva.
MX360041B (es) Composiciones y metodos para el cuidado personal.
CL2021001256A1 (es) Vacunación con el dominio alfa 3 de mica/b para el tratamiento del cáncer (divisional sol 201801470)
EA201692552A1 (ru) МОДИФИЦИРОВАННЫЕ МЕНИНГОКОККОВЫЕ ПОЛИПЕПТИДЫ fHbp
BR112016017112A2 (pt) Composições de apilimod e métodos de uso das mesmas
BR112017009000A2 (pt) apilimod para uso no tratamento de melanoma
BR112018070255A2 (pt) reprogramação cardíaca direta melhorada.
BR112016019389A8 (pt) Vacina, e, peptídeo
PH12016501838A1 (en) Compounds and their methods of use
JO3541B1 (ar) علاجات طبية قائمة على اناموريلين
BR112019004102A2 (pt) imunoterapia para poliomavírus
BR112016019395A2 (pt) composição
AU355238S (en) Dental appliance