PE20160184A1 - Comprimidos tragables de n-acetilcisteina - Google Patents

Comprimidos tragables de n-acetilcisteina

Info

Publication number
PE20160184A1
PE20160184A1 PE2015002421A PE2015002421A PE20160184A1 PE 20160184 A1 PE20160184 A1 PE 20160184A1 PE 2015002421 A PE2015002421 A PE 2015002421A PE 2015002421 A PE2015002421 A PE 2015002421A PE 20160184 A1 PE20160184 A1 PE 20160184A1
Authority
PE
Peru
Prior art keywords
acetyl cysteine
swallowable tablets
tablets
prepared
swallowable
Prior art date
Application number
PE2015002421A
Other languages
English (en)
Inventor
Alberto Moretto
Lazzari Alessandra De
Original Assignee
Zambon Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=48748383&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PE20160184(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Zambon Spa filed Critical Zambon Spa
Publication of PE20160184A1 publication Critical patent/PE20160184A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/12—Mucolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1688—Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pulmonology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Inorganic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

La presente invencion se refiere a comprimidos tragables que contienen por lo menos 80% en peso de N-acetilcisteina (NAC) y por lo menos un excipiente farmaceuticamente aceptable, en particular comprimidos, en los que el olor sulfuroso se encuentra ausente, caracterizado porque dicho comprimido se prepara utilizando un granulado preparado mediante un procedimiento de granulacion por via seca del principio activo solo, con el que se mezclan los excipientes antes de la compresion
PE2015002421A 2013-05-29 2014-05-27 Comprimidos tragables de n-acetilcisteina PE20160184A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT000874A ITMI20130874A1 (it) 2013-05-29 2013-05-29 Compresse deglutibili di n-acetilcisteina

Publications (1)

Publication Number Publication Date
PE20160184A1 true PE20160184A1 (es) 2016-04-27

Family

ID=48748383

Family Applications (1)

Application Number Title Priority Date Filing Date
PE2015002421A PE20160184A1 (es) 2013-05-29 2014-05-27 Comprimidos tragables de n-acetilcisteina

Country Status (30)

Country Link
US (1) US9808427B2 (es)
EP (1) EP3003278B1 (es)
JP (1) JP6438013B2 (es)
CN (1) CN105228595B (es)
AU (1) AU2014273148B2 (es)
BR (1) BR112015029038B1 (es)
CA (1) CA2911474C (es)
CY (1) CY1122114T1 (es)
DK (1) DK3003278T3 (es)
EA (1) EA031856B1 (es)
ES (1) ES2721649T3 (es)
HR (1) HRP20190687T1 (es)
HU (1) HUE044880T2 (es)
IL (1) IL242439B (es)
IT (1) ITMI20130874A1 (es)
LT (1) LT3003278T (es)
MX (1) MX366917B (es)
MY (1) MY174005A (es)
PE (1) PE20160184A1 (es)
PH (1) PH12015502608B1 (es)
PL (1) PL3003278T3 (es)
PT (1) PT3003278T (es)
RS (1) RS58653B1 (es)
SG (2) SG11201509177VA (es)
SI (1) SI3003278T1 (es)
SM (1) SMT201900234T1 (es)
TR (1) TR201906101T4 (es)
UA (1) UA117829C2 (es)
WO (1) WO2014191410A1 (es)
ZA (1) ZA201508411B (es)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI3554491T3 (fi) 2016-12-15 2023-04-26 Zambon Spa N-asetyylikysteiini käytettäväksi antibakteerisena aineena
US20250235416A1 (en) * 2017-09-20 2025-07-24 Nacuity Pharmaceuticals, Inc. Method for preparation of n-acetyl cysteine amide, derivatives and tablets thereof
IT201700109080A1 (it) * 2017-09-28 2019-03-28 Neilos S R L Composizione per la prevenzione e/o il trattamento delle affezioni delle vie respiratorie
WO2019086408A1 (en) * 2017-11-02 2019-05-09 Zambon S.P.A. Pharmaceutical compositions comprising safinamide
US10288629B1 (en) * 2017-12-19 2019-05-14 Aeterna Zentaris, Inc. Method of assessing growth hormone deficiency in humans by a macimorelin containing composition
CA3103324A1 (en) * 2018-06-14 2019-12-19 Poxel Film-coated tablet comprising a triazine derivative for use in the treatment of diabetes
IT201800007928A1 (it) * 2018-08-07 2020-02-07 Sofar Spa Composizione contenente un agente mucolitico per il trattamento di ipersecrezione di muco e dispositivo per il suo dosaggio
CA3132400A1 (en) * 2019-03-18 2020-09-24 Cedars-Sinai Medical Center Compositions and methods to treat gastrointestinal diseases and disorders
CN112843008A (zh) * 2021-02-07 2021-05-28 广东赛康制药厂有限公司 一种乙酰半胱氨酸片及其制备方法
CN114886860B (zh) * 2022-06-28 2023-04-25 山东达因海洋生物制药股份有限公司 一种乙酰半胱氨酸药物组合物及其制剂和制备工艺
CN119792224B (zh) * 2025-01-21 2025-08-08 江苏安必生制药有限公司 一种乙酰半胱氨酸泡腾片及其制备工艺

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0481294T4 (da) * 1990-10-19 2001-06-18 Spirig Ag Fast, hurtigt-opløseligt lægemiddelpræparat indeholdende N-acetylcystein
GB9305058D0 (en) * 1993-03-12 1993-04-28 Penn Pharm Ltd Pharmaceutical compositions
IT1311907B1 (it) * 1999-04-06 2002-03-20 Zambon Spa Compresse deglutibili ad alto contenuto di n-acetilcisteina.
US6623754B2 (en) * 2001-05-21 2003-09-23 Noveon Ip Holdings Corp. Dosage form of N-acetyl cysteine
JP2003155232A (ja) * 2001-09-07 2003-05-27 Takeda Chem Ind Ltd 不快な臭いが低減されたｌ−システイン配合固形製剤およびその製造方法
US20080139654A1 (en) * 2006-12-09 2008-06-12 Eric Mott Soderling Acetaminophen compositions having minimized side effects including reduced hepatotoxicity
IT1399492B1 (it) * 2010-04-13 2013-04-19 Alpex Pharma Sa Composizioni farmaceutiche effervescenti contenenti n-acetilcisteina.
EP2574333B1 (en) * 2011-09-27 2017-01-11 Friulchem SpA N-acetylcysteine effervescent tablet and its therapeutical applications

Also Published As

Publication number Publication date
EP3003278A1 (en) 2016-04-13
PL3003278T3 (pl) 2019-07-31
BR112015029038B1 (pt) 2022-12-06
SMT201900234T1 (it) 2019-05-10
MX366917B (es) 2019-07-30
AU2014273148A1 (en) 2015-11-26
AU2014273148B2 (en) 2019-02-28
ITMI20130874A1 (it) 2014-11-30
EP3003278B1 (en) 2019-02-27
CA2911474A1 (en) 2014-12-04
US9808427B2 (en) 2017-11-07
ZA201508411B (en) 2022-03-30
HUE044880T2 (hu) 2019-11-28
PH12015502608A1 (en) 2016-02-29
PT3003278T (pt) 2019-05-14
DK3003278T3 (da) 2019-05-06
WO2014191410A1 (en) 2014-12-04
MX2015016130A (es) 2016-08-08
LT3003278T (lt) 2019-05-10
HRP20190687T1 (hr) 2019-06-14
SG10201709861YA (en) 2018-01-30
CN105228595A (zh) 2016-01-06
IL242439B (en) 2020-01-30
UA117829C2 (uk) 2018-10-10
US20160113876A1 (en) 2016-04-28
BR112015029038A2 (pt) 2017-07-25
SG11201509177VA (en) 2015-12-30
EA031856B1 (ru) 2019-03-29
TR201906101T4 (tr) 2019-05-21
JP6438013B2 (ja) 2018-12-12
CN105228595B (zh) 2019-01-04
RS58653B1 (sr) 2019-05-31
SI3003278T1 (sl) 2019-08-30
PH12015502608B1 (en) 2016-02-29
MY174005A (en) 2020-03-03
CY1122114T1 (el) 2020-07-31
ES2721649T3 (es) 2019-08-02
EA201592172A1 (ru) 2016-05-31
JP2016520108A (ja) 2016-07-11
CA2911474C (en) 2021-04-13

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