PE20160184A1 - Comprimidos tragables de n-acetilcisteina - Google Patents
Comprimidos tragables de n-acetilcisteinaInfo
- Publication number
- PE20160184A1 PE20160184A1 PE2015002421A PE2015002421A PE20160184A1 PE 20160184 A1 PE20160184 A1 PE 20160184A1 PE 2015002421 A PE2015002421 A PE 2015002421A PE 2015002421 A PE2015002421 A PE 2015002421A PE 20160184 A1 PE20160184 A1 PE 20160184A1
- Authority
- PE
- Peru
- Prior art keywords
- acetyl cysteine
- swallowable tablets
- tablets
- prepared
- swallowable
- Prior art date
Links
- PWKSKIMOESPYIA-BYPYZUCNSA-N L-N-acetyl-Cysteine Chemical compound CC(=O)N[C@@H](CS)C(O)=O PWKSKIMOESPYIA-BYPYZUCNSA-N 0.000 title abstract 3
- 229960004308 acetylcysteine Drugs 0.000 title abstract 3
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 2
- 239000004480 active ingredient Substances 0.000 abstract 1
- 238000007906 compression Methods 0.000 abstract 1
- 230000006835 compression Effects 0.000 abstract 1
- 238000007908 dry granulation Methods 0.000 abstract 1
- 239000008187 granular material Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2009—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/12—Mucolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
- A61K9/1688—Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Inorganic Chemistry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
La presente invencion se refiere a comprimidos tragables que contienen por lo menos 80% en peso de N-acetilcisteina (NAC) y por lo menos un excipiente farmaceuticamente aceptable, en particular comprimidos, en los que el olor sulfuroso se encuentra ausente, caracterizado porque dicho comprimido se prepara utilizando un granulado preparado mediante un procedimiento de granulacion por via seca del principio activo solo, con el que se mezclan los excipientes antes de la compresion
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT000874A ITMI20130874A1 (it) | 2013-05-29 | 2013-05-29 | Compresse deglutibili di n-acetilcisteina |
Publications (1)
Publication Number | Publication Date |
---|---|
PE20160184A1 true PE20160184A1 (es) | 2016-04-27 |
Family
ID=48748383
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PE2015002421A PE20160184A1 (es) | 2013-05-29 | 2014-05-27 | Comprimidos tragables de n-acetilcisteina |
Country Status (29)
Country | Link |
---|---|
US (1) | US9808427B2 (es) |
EP (1) | EP3003278B1 (es) |
JP (1) | JP6438013B2 (es) |
CN (1) | CN105228595B (es) |
AU (1) | AU2014273148B2 (es) |
BR (1) | BR112015029038B1 (es) |
CA (1) | CA2911474C (es) |
CY (1) | CY1122114T1 (es) |
DK (1) | DK3003278T3 (es) |
EA (1) | EA031856B1 (es) |
ES (1) | ES2721649T3 (es) |
HR (1) | HRP20190687T1 (es) |
HU (1) | HUE044880T2 (es) |
IL (1) | IL242439B (es) |
IT (1) | ITMI20130874A1 (es) |
LT (1) | LT3003278T (es) |
MX (1) | MX366917B (es) |
MY (1) | MY174005A (es) |
PE (1) | PE20160184A1 (es) |
PH (1) | PH12015502608B1 (es) |
PL (1) | PL3003278T3 (es) |
PT (1) | PT3003278T (es) |
RS (1) | RS58653B1 (es) |
SG (2) | SG10201709861YA (es) |
SI (1) | SI3003278T1 (es) |
TR (1) | TR201906101T4 (es) |
UA (1) | UA117829C2 (es) |
WO (1) | WO2014191410A1 (es) |
ZA (1) | ZA201508411B (es) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EA201991331A1 (ru) | 2016-12-15 | 2019-11-29 | N-ацетилцистеин для применения в качестве антибактериального агента | |
IT201700109080A1 (it) * | 2017-09-28 | 2019-03-28 | Neilos S R L | Composizione per la prevenzione e/o il trattamento delle affezioni delle vie respiratorie |
WO2019086408A1 (en) * | 2017-11-02 | 2019-05-09 | Zambon S.P.A. | Pharmaceutical compositions comprising safinamide |
US10288629B1 (en) * | 2017-12-19 | 2019-05-14 | Aeterna Zentaris, Inc. | Method of assessing growth hormone deficiency in humans by a macimorelin containing composition |
WO2019238647A1 (en) * | 2018-06-14 | 2019-12-19 | Poxel | Film-coated tablet comprising a triazine derivative for use in the treatment of diabetes |
IT201800007928A1 (it) * | 2018-08-07 | 2020-02-07 | Sofar Spa | Composizione contenente un agente mucolitico per il trattamento di ipersecrezione di muco e dispositivo per il suo dosaggio |
CN112843008A (zh) * | 2021-02-07 | 2021-05-28 | 广东赛康制药厂有限公司 | 一种乙酰半胱氨酸片及其制备方法 |
CN114886860B (zh) * | 2022-06-28 | 2023-04-25 | 山东达因海洋生物制药股份有限公司 | 一种乙酰半胱氨酸药物组合物及其制剂和制备工艺 |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0481294B2 (de) * | 1990-10-19 | 2001-04-11 | Spirig Ag Pharmazeutische Präparate | Feste, schnell-lösliche Arzneimittelzubereitung enthaltend N-Acetylcystein |
GB9305058D0 (en) * | 1993-03-12 | 1993-04-28 | Penn Pharm Ltd | Pharmaceutical compositions |
IT1311907B1 (it) | 1999-04-06 | 2002-03-20 | Zambon Spa | Compresse deglutibili ad alto contenuto di n-acetilcisteina. |
US6623754B2 (en) * | 2001-05-21 | 2003-09-23 | Noveon Ip Holdings Corp. | Dosage form of N-acetyl cysteine |
JP2003155232A (ja) * | 2001-09-07 | 2003-05-27 | Takeda Chem Ind Ltd | 不快な臭いが低減されたl−システイン配合固形製剤およびその製造方法 |
US20080139654A1 (en) * | 2006-12-09 | 2008-06-12 | Eric Mott Soderling | Acetaminophen compositions having minimized side effects including reduced hepatotoxicity |
IT1399492B1 (it) * | 2010-04-13 | 2013-04-19 | Alpex Pharma Sa | Composizioni farmaceutiche effervescenti contenenti n-acetilcisteina. |
EP2574333B1 (en) * | 2011-09-27 | 2017-01-11 | Friulchem SpA | N-acetylcysteine effervescent tablet and its therapeutical applications |
-
2013
- 2013-05-29 IT IT000874A patent/ITMI20130874A1/it unknown
-
2014
- 2014-05-27 EP EP14728495.4A patent/EP3003278B1/en active Active
- 2014-05-27 EA EA201592172A patent/EA031856B1/ru unknown
- 2014-05-27 RS RS20190507A patent/RS58653B1/sr unknown
- 2014-05-27 ES ES14728495T patent/ES2721649T3/es active Active
- 2014-05-27 DK DK14728495.4T patent/DK3003278T3/da active
- 2014-05-27 SI SI201431172T patent/SI3003278T1/sl unknown
- 2014-05-27 PL PL14728495T patent/PL3003278T3/pl unknown
- 2014-05-27 MX MX2015016130A patent/MX366917B/es active IP Right Grant
- 2014-05-27 AU AU2014273148A patent/AU2014273148B2/en active Active
- 2014-05-27 HU HUE14728495 patent/HUE044880T2/hu unknown
- 2014-05-27 JP JP2016516129A patent/JP6438013B2/ja active Active
- 2014-05-27 TR TR2019/06101T patent/TR201906101T4/tr unknown
- 2014-05-27 SG SG10201709861YA patent/SG10201709861YA/en unknown
- 2014-05-27 WO PCT/EP2014/060950 patent/WO2014191410A1/en active Application Filing
- 2014-05-27 BR BR112015029038-8A patent/BR112015029038B1/pt active IP Right Grant
- 2014-05-27 LT LTEP14728495.4T patent/LT3003278T/lt unknown
- 2014-05-27 SG SG11201509177VA patent/SG11201509177VA/en unknown
- 2014-05-27 UA UAA201512351A patent/UA117829C2/uk unknown
- 2014-05-27 PT PT14728495T patent/PT3003278T/pt unknown
- 2014-05-27 US US14/893,100 patent/US9808427B2/en active Active
- 2014-05-27 PE PE2015002421A patent/PE20160184A1/es active IP Right Grant
- 2014-05-27 MY MYPI2015704193A patent/MY174005A/en unknown
- 2014-05-27 CA CA2911474A patent/CA2911474C/en active Active
- 2014-05-27 CN CN201480029563.1A patent/CN105228595B/zh active Active
-
2015
- 2015-11-04 IL IL242439A patent/IL242439B/en active IP Right Grant
- 2015-11-13 ZA ZA2015/08411A patent/ZA201508411B/en unknown
- 2015-11-23 PH PH12015502608A patent/PH12015502608B1/en unknown
-
2019
- 2019-04-11 CY CY20191100404T patent/CY1122114T1/el unknown
- 2019-04-11 HR HRP20190687TT patent/HRP20190687T1/hr unknown
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Legal Events
Date | Code | Title | Description |
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FG | Grant, registration |