PE20141676A1 - Composiciones de yodo-povidona estable - Google Patents

Composiciones de yodo-povidona estable

Info

Publication number
PE20141676A1
PE20141676A1 PE2014000281A PE2014000281A PE20141676A1 PE 20141676 A1 PE20141676 A1 PE 20141676A1 PE 2014000281 A PE2014000281 A PE 2014000281A PE 2014000281 A PE2014000281 A PE 2014000281A PE 20141676 A1 PE20141676 A1 PE 20141676A1
Authority
PE
Peru
Prior art keywords
povidone
composition
iodine
stable iodine
alcohol
Prior art date
Application number
PE2014000281A
Other languages
English (en)
Inventor
Joseph Capriotti
Bo Liang
Michael C Samson
Jason Stein
Michael Weiser
Original Assignee
Foresigth Biotherapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=47883771&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PE20141676(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Foresigth Biotherapeutics Inc filed Critical Foresigth Biotherapeutics Inc
Publication of PE20141676A1 publication Critical patent/PE20141676A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/785—Polymers containing nitrogen
    • A61K31/787—Polymers containing nitrogen containing heterocyclic rings having nitrogen as a ring hetero atom
    • A61K31/79—Polymers of vinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N59/00—Biocides, pest repellants or attractants, or plant growth regulators containing elements or inorganic compounds
    • A01N59/12—Iodine, e.g. iodophors; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/196—Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
    • A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4535—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a heterocyclic ring having sulfur as a ring hetero atom, e.g. pizotifen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/18—Iodine; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0046—Ear
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Abstract

SE REFIERE A UNA COMPOSICION QUE COMPRENDE: a) YODO-POVIDONA (PVP-I) A UNA CONCENTRACION DE 0,4% Y 12,5% EN PESO; Y b) UN SEGUNDO COMPONENTE SELECCIONADO DE: (i) UN ANTIINFLAMATORIO NO ESTEROIDE (NSAID) TAL COMO FUMARATO DE KETOTIFEN, DICLOFENAC SODICO, KETOROLAC, TROMETAMINA, SUPROFENO, ENTRE OTROS, Y (ii) UN ESTEROIDE TAL COMO MEDRISONA, DEXAMETASONA, ALCOHOL DE DEXAMETASONA, ACETATO DE PREDNISOLONA, HIDROCORTISONA, ENTRE OTROS. DICHA COMPOSICION ES UTIL PARA EL TRATAMIENTO DE UNA INFECCION OTICA
PE2014000281A 2011-09-16 2012-09-14 Composiciones de yodo-povidona estable PE20141676A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201161535667P 2011-09-16 2011-09-16

Publications (1)

Publication Number Publication Date
PE20141676A1 true PE20141676A1 (es) 2014-11-06

Family

ID=47883771

Family Applications (1)

Application Number Title Priority Date Filing Date
PE2014000281A PE20141676A1 (es) 2011-09-16 2012-09-14 Composiciones de yodo-povidona estable

Country Status (16)

Country Link
US (1) US20150164939A1 (es)
EP (2) EP2755477A4 (es)
JP (3) JP6539444B2 (es)
KR (2) KR20190099084A (es)
CN (2) CN107595879A (es)
AR (1) AR087857A1 (es)
AU (2) AU2012308424B2 (es)
BR (1) BR112014005487A2 (es)
CA (1) CA2847364C (es)
CL (2) CL2014000592A1 (es)
CO (1) CO6930368A2 (es)
EC (1) ECSP14013302A (es)
MX (1) MX2014002679A (es)
PE (1) PE20141676A1 (es)
TW (4) TW201808311A (es)
WO (1) WO2013040347A1 (es)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101967938B1 (ko) * 2011-05-12 2019-04-10 포어사이트 바이오쎄라퓨틱스, 인코퍼레이티드 스테로이드 또는 비-스테로이드성 소염제를 갖는 안정한 포비돈-요오드 조성물
US11596599B2 (en) 2012-05-03 2023-03-07 The Johns Hopkins University Compositions and methods for ophthalmic and/or other applications
CA2871745C (en) 2012-05-03 2023-01-24 Kala Pharmaceuticals, Inc. Pharmaceutical nanoparticles showing improved mucosal transport
US9827191B2 (en) 2012-05-03 2017-11-28 The Johns Hopkins University Compositions and methods for ophthalmic and/or other applications
KR102140989B1 (ko) 2012-05-03 2020-08-04 칼라 파마슈티컬스, 인크. 개선된 점막 수송을 나타내는 제약 나노입자
JP6669499B2 (ja) 2013-02-15 2020-03-18 カラ ファーマシューティカルズ インコーポレイテッド 治療用化合物
JP2016510000A (ja) 2013-02-20 2016-04-04 カラ ファーマシューティカルズ インコーポレイテッド 治療用化合物およびその使用
US9688688B2 (en) 2013-02-20 2017-06-27 Kala Pharmaceuticals, Inc. Crystalline forms of 4-((4-((4-fluoro-2-methyl-1H-indol-5-yl)oxy)-6-methoxyquinazolin-7-yl)oxy)-1-(2-oxa-7-azaspiro[3.5]nonan-7-yl)butan-1-one and uses thereof
US9890173B2 (en) 2013-11-01 2018-02-13 Kala Pharmaceuticals, Inc. Crystalline forms of therapeutic compounds and uses thereof
KR20160099084A (ko) 2013-11-01 2016-08-19 칼라 파마슈티컬스, 인크. 치료 화합물의 결정질 형태 및 그의 용도
EP3365022A4 (en) * 2015-10-25 2019-07-24 IVIEW Therapeutics, Inc. PHARMACEUTICAL FORMULATIONS THAT FORM A GEL IN SITU
CA3036340A1 (en) 2016-09-08 2018-03-15 Kala Pharmaceuticals, Inc. Crystalline forms of therapeutic compounds and uses thereof
AU2017324251A1 (en) 2016-09-08 2019-03-21 Kala Pharmaceuticals, Inc. Crystalline forms of therapeutic compounds and uses thereof
US10253036B2 (en) 2016-09-08 2019-04-09 Kala Pharmaceuticals, Inc. Crystalline forms of therapeutic compounds and uses thereof
JP6255134B1 (ja) * 2016-11-02 2017-12-27 ヴェローチェ・バイオファーマ・エルエルシー 耳炎の治療のための組成物および方法
EP3612228B1 (en) * 2017-04-21 2023-08-23 Dermaliq Therapeutics, Inc. Iodine compositions
CN110559175A (zh) * 2019-08-27 2019-12-13 陈文龙 一种结膜囊消毒溶液及其使用方法和装置
US20230181625A1 (en) * 2021-12-14 2023-06-15 Harrow Ip, Llc Method and composition for treating infectious conjunctivitis

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3886268A (en) 1972-05-30 1975-05-27 Synergistics Iodophor-steroid compound pharmaceutical compositions
US4113857A (en) 1977-05-16 1978-09-12 The Purdue Frederick Company Process for the preparation of iodophor compounds and methods for stabilizing iodophor pharmaceutical compositions containing the same
US4954351A (en) * 1983-03-02 1990-09-04 Euroceltique S.A. Method of producing standardized povidone iodine preparations and such preparations
US4996048A (en) 1988-11-30 1991-02-26 Euroceltique, S.A. Stabilizing packaged iodophor and minimizing leaching of iodine through packaging
US5232692A (en) * 1989-04-28 1993-08-03 Research And Education Institute, Inc. Povidone-iodine neonatal ophthalmic antimicrobial prophylactic agent
US5126127A (en) 1991-07-16 1992-06-30 Euroceltique, S.A. Stabilized PVP-I solutions
IL135222A (en) * 2000-03-22 2005-06-19 Univ Ben Gurion Compositions containing molecular iodine
WO2003092669A2 (en) * 2002-05-03 2003-11-13 Alcon, Inc. Method of treating vascular endothelial growth factor mediated vascular disorders using amfenac or nepafenac
US20060280809A1 (en) * 2005-06-14 2006-12-14 Leshchiner Adele K Anti-infective iodine based compositions for otic and nasal use
US7767217B2 (en) * 2006-03-14 2010-08-03 Foresight Biotherapeutics Ophthalmic compositions comprising povidone-iodine
US20090092574A1 (en) * 2006-12-29 2009-04-09 Scott Richard W Ophthalmic And Otic Compositions Of Facially Amphiphilic Polymers And Oligomers And Uses Thereof
WO2009071594A1 (en) * 2007-12-04 2009-06-11 Novagali Pharma Sa Compositions comprising corticosteroid prodrug such as dexamethasone palmitate for the treatment of eye disorders
US20090263345A1 (en) * 2008-01-28 2009-10-22 Foresight Biotherapeutics, Inc. Otic compositions for the treatment of infections of the internal and external ear in mammals
CN101965183A (zh) * 2008-02-21 2011-02-02 伊斯塔药品公司 作为佐剂的眼用nsaid
AU2009258145A1 (en) * 2008-06-12 2009-12-17 Foresight Biotherapeutics, Inc. Povidone iodine, a novel alternative preservative for ophthalmic compositions
JP2010059058A (ja) * 2008-09-01 2010-03-18 Kowa Co 鎮痛・抗炎症剤含有外用剤
JP5410071B2 (ja) * 2008-10-07 2014-02-05 久光製薬株式会社 エステル化抑制剤及びエステル化抑制方法
TWI618539B (zh) * 2009-12-15 2018-03-21 遠景生物製藥股份有限公司 無刺激性眼用聚乙烯吡咯啶酮-碘組成物
KR101967938B1 (ko) * 2011-05-12 2019-04-10 포어사이트 바이오쎄라퓨틱스, 인코퍼레이티드 스테로이드 또는 비-스테로이드성 소염제를 갖는 안정한 포비돈-요오드 조성물

Also Published As

Publication number Publication date
MX2014002679A (es) 2014-04-25
JP2018024689A (ja) 2018-02-15
EP2755477A4 (en) 2015-05-06
CA2847364A1 (en) 2013-03-21
TW201325601A (zh) 2013-07-01
AR087857A1 (es) 2014-04-23
KR20190099084A (ko) 2019-08-23
US20150164939A1 (en) 2015-06-18
JP2020007324A (ja) 2020-01-16
CO6930368A2 (es) 2014-04-28
CL2014000592A1 (es) 2014-11-03
CN103889218A (zh) 2014-06-25
CA2847364C (en) 2020-08-25
TW202126313A (zh) 2021-07-16
EP2755477A1 (en) 2014-07-23
TW201808311A (zh) 2018-03-16
JP2014526514A (ja) 2014-10-06
ECSP14013302A (es) 2014-05-31
BR112014005487A2 (pt) 2017-03-21
AU2012308424A1 (en) 2013-05-02
KR20140077900A (ko) 2014-06-24
CL2017001952A1 (es) 2018-03-16
EP3556372A1 (en) 2019-10-23
TW202023575A (zh) 2020-07-01
CN107595879A (zh) 2018-01-19
WO2013040347A1 (en) 2013-03-21
AU2016204700B2 (en) 2018-03-22
JP6539444B2 (ja) 2019-07-03
AU2016204700A1 (en) 2016-07-21
AU2012308424B2 (en) 2016-08-04

Similar Documents

Publication Publication Date Title
PE20141676A1 (es) Composiciones de yodo-povidona estable
CO7180221A2 (es) Composiciones fungicidas
CR20140305A (es) Novedosas dihidropirimidinoisoquinolinonas y composiciones farmacéuticas de las mismas para el tratamiento de transtornos inflamatorios
GT201400111A (es) Triazolopiridinas sustituidas
EA201400537A1 (ru) 18-МЕТИЛ-6,7-МЕТИЛЕН-3-ОКСО-17-ПРЕГН-4-ЕН-21,17β-КАРБОЛАКТОНЫ, ФАРМАЦЕВТИЧЕСКИЕ КОМПОЗИЦИИ, СОДЕРЖАЩИЕ УКАЗАННЫЕ СОЕДИНЕНИЯ, И ИХ ПРИМЕНЕНИЕ В ЛЕЧЕНИИ ЭНДОМЕТРИОЗА
EA201590053A1 (ru) Модуляторы пути системы комплемента и их применение
PE20150092A1 (es) Composiciones farmaceuticas que contienen fumarato de dimetilo
ECSP14013231A (es) Imidazopiridazinas sustituidas con amino
CL2012002067A1 (es) Composición herbicida que contiene una cantidad efectiva de una mezcla herbicida que contiene aminopyralid y 2,4-diclorofenoxiacético; dicha mezcla herbicida; y método para controlar vegetación no deseada, por ejemplo, en el arroz.
PE20141152A1 (es) Triterpenoides c-17 y c-3 modificados con actividad inhibidora de la maduracion del virus de inmunodeficiencia humana
ECSP099552A (es) Compuestos triciclicos, composiciones y procedimientos
NI201300068A (es) Moduladores del receptor de glucagón
CR20130569A (es) Análogos del ácido epoxieicosatrienoicos y métodos de toma y uso del mismo
CO6741223A2 (es) Derivados de azetidina útiles para el tratamiento de enfermedades metabólicas e inflamatorias
UA113620C2 (xx) Композиція, що містить аморфну (5-фтор-2-метил-3-хінолін-2-ілметиліндол-1-іл)оцтову кислоту
AR089269A1 (es) Composiciones para el cuidado oral
UY34166A (es) Composición farmacéutica oftalmológica tópica que contiene regorafenib
MX367926B (es) Composicion farmaceutica para liberacion sostenida de lanreotida.
AR084832A1 (es) Derivado cristalino de oxazina
EA201490573A1 (ru) Соединение бензотиазолона
FR2980709B1 (fr) Compositions contenant de la spermine et compositions pharmaceutiques les contenant
CU20130004A7 (es) Agentes terapéuticos 976
BR112012029565A2 (pt) composição farmacêutica de liberação controlada de losartana.
EA201690236A1 (ru) Производные индол-3-карбинола
PH12016501098A1 (en) Polymorphic and amorphous forms of cortisol 17-alpha-benzoate and methods for the preparation and use thereof

Legal Events

Date Code Title Description
FC Refusal