PE20140872A1 - Uso de laquinimod para reducir la fatiga, mejorar el estado funcional y mejorar la calidad de vida en pacientes con esclerosis multiple - Google Patents
Uso de laquinimod para reducir la fatiga, mejorar el estado funcional y mejorar la calidad de vida en pacientes con esclerosis multipleInfo
- Publication number
- PE20140872A1 PE20140872A1 PE2013001357A PE2013001357A PE20140872A1 PE 20140872 A1 PE20140872 A1 PE 20140872A1 PE 2013001357 A PE2013001357 A PE 2013001357A PE 2013001357 A PE2013001357 A PE 2013001357A PE 20140872 A1 PE20140872 A1 PE 20140872A1
- Authority
- PE
- Peru
- Prior art keywords
- laquinimod
- improve
- patients
- life
- multiple sclerosis
- Prior art date
Links
- GKWPCEFFIHSJOE-UHFFFAOYSA-N laquinimod Chemical compound OC=1C2=C(Cl)C=CC=C2N(C)C(=O)C=1C(=O)N(CC)C1=CC=CC=C1 GKWPCEFFIHSJOE-UHFFFAOYSA-N 0.000 title abstract 4
- 229960004577 laquinimod Drugs 0.000 title abstract 4
- 201000006417 multiple sclerosis Diseases 0.000 title 1
- 150000003839 salts Chemical class 0.000 abstract 2
- 208000034189 Sclerosis Diseases 0.000 abstract 1
- 230000006735 deficit Effects 0.000 abstract 1
- 230000004112 neuroprotection Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4704—2-Quinolinones, e.g. carbostyril
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Epidemiology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Hospice & Palliative Care (AREA)
- Nutrition Science (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US42074210P | 2010-12-07 | 2010-12-07 | |
| US201161542996P | 2011-10-04 | 2011-10-04 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PE20140872A1 true PE20140872A1 (es) | 2014-08-09 |
Family
ID=46162796
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PE2013001357A PE20140872A1 (es) | 2010-12-07 | 2011-12-06 | Uso de laquinimod para reducir la fatiga, mejorar el estado funcional y mejorar la calidad de vida en pacientes con esclerosis multiple |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US20120142730A1 (enExample) |
| EP (1) | EP2648732A4 (enExample) |
| JP (2) | JP2013544887A (enExample) |
| KR (1) | KR20130124518A (enExample) |
| CN (1) | CN103260624B (enExample) |
| AU (2) | AU2011338647A1 (enExample) |
| BR (1) | BR112013014061A2 (enExample) |
| CA (1) | CA2820586A1 (enExample) |
| CL (1) | CL2013001602A1 (enExample) |
| EA (1) | EA201390827A1 (enExample) |
| IL (1) | IL250726A0 (enExample) |
| MX (1) | MX2013006464A (enExample) |
| NZ (1) | NZ611628A (enExample) |
| PE (1) | PE20140872A1 (enExample) |
| PH (1) | PH12013501193A1 (enExample) |
| SG (2) | SG190449A1 (enExample) |
| UA (1) | UA111959C2 (enExample) |
| WO (1) | WO2012078591A1 (enExample) |
| ZA (1) | ZA201304237B (enExample) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1937642B1 (en) * | 2005-10-19 | 2014-09-10 | Teva Pharmaceutical Industries Ltd | Crystals of laquinimod sodium, and process for the manufacture thereof |
| EP2977049A1 (en) | 2007-12-20 | 2016-01-27 | Teva Pharmaceutical Industries, Ltd. | Stable laquinimod preparations |
| RS54707B1 (sr) * | 2009-07-30 | 2016-08-31 | Teva Pharmaceutical Industries Ltd. | Tretman kronove bolesti lakvinimodom |
| PL3064206T3 (pl) | 2009-08-10 | 2020-02-28 | Active Biotech Ab | Leczenie choroby Huntingtona z zastosowaniem lakwinimodu |
| NZ602510A (en) * | 2010-03-03 | 2014-11-28 | Teva Pharma | Treatment of lupus nephritis using laquinimod |
| SG183513A1 (en) * | 2010-03-03 | 2012-09-27 | Teva Pharma | Treatment of rheumatoid arthritis with a combination of laquinimod and methotrexate |
| MX2013000333A (es) | 2010-07-09 | 2013-02-26 | Teva Pharma | N-etil-n-fenil-1,2-dihidro-4-hidroxi-5-cloro-1-metil-2-oxoquinoli na-3-carboxamida deuterada, sales y usos de la misma. |
| SG11201401330YA (en) | 2011-10-12 | 2014-05-29 | Teva Pharma | Treatment of multiple sclerosis with combination of laquinimod and fingolimod |
| CN106063787A (zh) | 2012-02-03 | 2016-11-02 | 泰华制药工业有限公司 | 拉喹莫德用于治疗一线抗TNFα疗法失败的克罗恩氏病患者的用途 |
| KR20140138725A (ko) | 2012-02-16 | 2014-12-04 | 테바 파마슈티컬 인더스트리즈 리미티드 | N-에틸-n-페닐-1,2-디하이드로-4,5-디-하이드록시-1-메틸-2-옥소-3-퀴놀린카복사미드, 그의 제조 및 용도 |
| TW201350467A (zh) | 2012-05-08 | 2013-12-16 | Teva Pharma | N-乙基-4-羥基-1-甲基-5-(甲基(2,3,4,5,6-五羥基己基)胺基)-2-側氧-n-苯基-1,2-二氫喹啉-3-甲醯胺 |
| TW201400117A (zh) | 2012-06-05 | 2014-01-01 | Teva Pharma | 使用拉喹莫德治療眼發炎疾病 |
| TW201410244A (zh) | 2012-08-13 | 2014-03-16 | Teva Pharma | 用於治療gaba媒介之疾病之拉喹莫德(laquinimod) |
| IN2015DN03219A (enExample) * | 2012-09-27 | 2015-10-02 | Teva Pharma | |
| EA201590726A1 (ru) * | 2012-10-12 | 2015-10-30 | Тева Фармасьютикал Индастриз Лтд. | Лахинимод для уменьшения таламического поражения при рассеянном склерозе |
| HK1212936A1 (zh) | 2012-11-07 | 2016-06-24 | Teva Pharmaceutical Industries Ltd. | 拉喹莫德胺盐 |
| SG11201505818WA (en) * | 2013-02-15 | 2015-08-28 | Teva Pharma | Treatment of multiple sclerosis with laquinimod |
| HK1220125A1 (zh) | 2013-03-14 | 2017-04-28 | Teva Pharmaceutical Industries Ltd. | 拉喹莫德的透皮配方 |
| NZ630427A (en) | 2013-03-14 | 2017-06-30 | Teva Pharma | Crystals of laquinimod sodium and improved process for the manufacture thereof |
| AU2014364447A1 (en) * | 2013-12-20 | 2016-08-04 | Teva Pharmaceutical Industries Ltd. | Use of laquinimod to delay Huntington's disease progression |
| US20160331742A1 (en) * | 2014-01-17 | 2016-11-17 | Teva Pharmaceutical Industries, Ltd. | Treatment of crohn's disease using low doses of laquinimod |
| UY36099A (es) | 2014-04-29 | 2016-02-29 | Teva Pharma | Laquinimod para el tratamiento de pacientes con esclerosis múltiple remitente recurrente (rrms) con un alto grado de discapacidad |
| US10537566B2 (en) | 2014-10-16 | 2020-01-21 | Novartis Ag | Combinations comprising siponimod and laquinimod for the treatment of multiple sclerosis |
| MX2017008136A (es) | 2014-12-22 | 2018-03-06 | Teva Pharmaceuticals Int Gmbh | Sal de l-tartrato de pridopidina. |
| CN112770748A (zh) * | 2018-10-09 | 2021-05-07 | 美迪诺亚公司 | 异丁司特和干扰素-β的组合及其使用方法 |
| CA3145269A1 (en) * | 2019-07-22 | 2021-01-28 | Michel BURCKLEN | Use of ponesimod for the treatment of multiple sclerosis |
| CN110688373A (zh) * | 2019-09-17 | 2020-01-14 | 杭州绿度信息技术有限公司 | 一种基于逻辑回归的offset方法 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7560100B2 (en) * | 2004-09-09 | 2009-07-14 | Yeda Research And Development Co., Ltd. | Mixtures of polypeptides, compositions containing and processes for preparing same, for treating neurodegenerative diseases |
| US20060205822A1 (en) * | 2004-12-22 | 2006-09-14 | Forest Laboratories, Inc. | 1-Aminocyclohexane derivatives for the treatment of multiple sclerosis, emotional lability and pseudobulbar affect |
| US9168286B2 (en) * | 2005-10-13 | 2015-10-27 | Human Genome Sciences, Inc. | Methods and compositions for use in treatment of patients with autoantibody positive disease |
| BRPI0713694A2 (pt) * | 2006-06-12 | 2012-10-30 | Teva Pharma | composição farmacêutica, processo para preparar composição farmacêutica, embalagens vedada, métodos para tratar um indivìduo afligido com uma forma de esclerose múltipla, e para aliviar um sintoma de esclerose múltipla em um indivìduo afligido com uma forma de esclerose múltipla, e, uso da composição farmacêutica |
| PT2653873T (pt) * | 2007-02-08 | 2022-07-26 | Biogen Ma Inc | Composições e utilizações para o tratamento de esclerose múltipla |
| CN107308162A (zh) * | 2009-06-19 | 2017-11-03 | 泰华制药工业有限公司 | 利用拉喹莫德治疗多发性硬化 |
-
2011
- 2011-12-06 UA UAA201308448A patent/UA111959C2/uk unknown
- 2011-12-06 EA EA201390827A patent/EA201390827A1/ru unknown
- 2011-12-06 NZ NZ611628A patent/NZ611628A/en not_active IP Right Cessation
- 2011-12-06 MX MX2013006464A patent/MX2013006464A/es unknown
- 2011-12-06 WO PCT/US2011/063460 patent/WO2012078591A1/en not_active Ceased
- 2011-12-06 AU AU2011338647A patent/AU2011338647A1/en not_active Abandoned
- 2011-12-06 PH PH1/2013/501193A patent/PH12013501193A1/en unknown
- 2011-12-06 SG SG2013042403A patent/SG190449A1/en unknown
- 2011-12-06 JP JP2013543255A patent/JP2013544887A/ja active Pending
- 2011-12-06 PE PE2013001357A patent/PE20140872A1/es not_active Application Discontinuation
- 2011-12-06 BR BR112013014061A patent/BR112013014061A2/pt not_active Application Discontinuation
- 2011-12-06 CA CA2820586A patent/CA2820586A1/en not_active Abandoned
- 2011-12-06 EP EP11846599.6A patent/EP2648732A4/en not_active Withdrawn
- 2011-12-06 CN CN201180060414.8A patent/CN103260624B/zh not_active Expired - Fee Related
- 2011-12-06 KR KR1020137017362A patent/KR20130124518A/ko not_active Ceased
- 2011-12-06 SG SG10201509831XA patent/SG10201509831XA/en unknown
- 2011-12-06 US US13/312,284 patent/US20120142730A1/en not_active Abandoned
-
2013
- 2013-06-05 CL CL2013001602A patent/CL2013001602A1/es unknown
- 2013-06-10 ZA ZA2013/04237A patent/ZA201304237B/en unknown
-
2016
- 2016-12-26 JP JP2016251360A patent/JP2017095476A/ja active Pending
-
2017
- 2017-02-22 IL IL250726A patent/IL250726A0/en unknown
- 2017-03-28 AU AU2017202055A patent/AU2017202055A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| UA111959C2 (uk) | 2016-07-11 |
| CN103260624B (zh) | 2015-06-03 |
| WO2012078591A8 (en) | 2012-08-02 |
| CN103260624A (zh) | 2013-08-21 |
| CA2820586A1 (en) | 2012-06-14 |
| PH12013501193A1 (en) | 2013-07-15 |
| JP2013544887A (ja) | 2013-12-19 |
| US20120142730A1 (en) | 2012-06-07 |
| EP2648732A1 (en) | 2013-10-16 |
| CL2013001602A1 (es) | 2013-10-25 |
| NZ611628A (en) | 2015-06-26 |
| AU2011338647A8 (en) | 2013-09-05 |
| AU2017202055A1 (en) | 2017-04-20 |
| AU2011338647A1 (en) | 2013-07-04 |
| EA201390827A1 (ru) | 2013-12-30 |
| SG190449A1 (en) | 2013-07-31 |
| SG10201509831XA (en) | 2015-12-30 |
| BR112013014061A2 (pt) | 2016-09-13 |
| ZA201304237B (en) | 2014-08-27 |
| JP2017095476A (ja) | 2017-06-01 |
| KR20130124518A (ko) | 2013-11-14 |
| WO2012078591A1 (en) | 2012-06-14 |
| EP2648732A4 (en) | 2014-04-30 |
| MX2013006464A (es) | 2013-07-29 |
| IL250726A0 (en) | 2017-04-30 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| PE20140872A1 (es) | Uso de laquinimod para reducir la fatiga, mejorar el estado funcional y mejorar la calidad de vida en pacientes con esclerosis multiple | |
| CY1124135T1 (el) | Δοσολογικα σχηματα για την αγωγη της νοσου ρομρε | |
| PH12015502691A1 (en) | Use of high dose pridopidine for treating huntington's disease | |
| RU2014109074A (ru) | ИНГИБИТОРЫ ФАННИ-ТОКА (If), ПРЕДНАЗНАЧЕННЫЕ ДЛЯ ПРИМЕНЕНИЯ В СПОСОБЕ ЛЕЧЕНИЯ И ПРЕДУПРЕЖДЕНИЯ СЕРДЕЧНОЙ НЕДОСТАТОЧНОСТИ У КОШАЧЬИХ | |
| MX2011013902A (es) | Tratamiento de esclerosis multiple con laquinimod. | |
| PE20142319A1 (es) | Tratamiento de esclerosis multiple con combinacion de laquinimod y acetato de glatiramero | |
| AR086356A1 (es) | Combinacion farmaceutica para usar en el tratamiento de pacientes que padecen diabetes de tipo 2 | |
| NZ589445A (en) | Rasagiline for parkinson's disease modification | |
| AR089862A1 (es) | USO DE LAQUINIMOD PARA EL TRATAMIENTO DE PACIENTES CON ENFERMEDAD DE CROHN EN QUIENES FRACASO UNA TERAPIA ANTI-FACTOR DE NECROSIS TUMORAL a (ANTI-TNFa) DE PRIMERA LINEA | |
| NZ594056A (en) | New stable formulations of recombinant human albumin-human granulocyte colony stimulating factor fusion protein | |
| PH12014500386A1 (en) | Combination treatment for hepatitis c | |
| MX2014013039A (es) | Uso de laquinimod de dosis alta para el tratamiento de esclerosis multiple. | |
| NZ600544A (en) | Compositions and methods for the treatment of angiogenesis-related eye diseases | |
| FI3439660T3 (fi) | Pimobendaanin käyttö sydämen koon pienentämiseen ja kliinisten oireiden alkamisen hidastamiseen potilaissa, joilla on hiippaläppäsairaudesta johtuva oireeton sydämen vajaatoiminta | |
| MX344303B (es) | Metodos para proveer terapia de perdida de peso en pacientes con depresion mayor. | |
| CL2020000491A1 (es) | Métodos para aumentar y/o estabilizar la función cardiaca en pacientes con enfermedad de fabry. | |
| NZ700924A (en) | Dosage regimen for a pi-3 kinase inhibitor | |
| MX341660B (es) | Agonista del receptor de ghrelina para el tratamiento de caquexia. | |
| MX2015014939A (es) | Nuevo uso de clorhidrato de landiolol en el tratamiento a largo plazo de taquiarritmias e hipertension. | |
| NZ597675A (en) | Medicament for the long term nsaid use | |
| AR047154A1 (es) | Tratamiento del insomnio en pacientes humanos administrandoles una cantidad diaria de gaboxadol | |
| MX2021007324A (es) | Terapia oral con acido 6,8-bis-benciltio-octanoico. | |
| AR080380A1 (es) | Tratamiento de la demencia tipo alzheimer con masitinib | |
| NZ599227A (en) | Therapeutic agent for chronic pain | |
| NZ726034A (en) | Methods for treating an impairment in gait and/or balance in patients with multiple sclerosis using an aminopyridine |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC | Refusal |