CA2820586A1 - Use of laquinimod for reducing fatigue, improving functional status, and improving quality of life in multiple sclerosis patients - Google Patents
Use of laquinimod for reducing fatigue, improving functional status, and improving quality of life in multiple sclerosis patients Download PDFInfo
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- CA2820586A1 CA2820586A1 CA2820586A CA2820586A CA2820586A1 CA 2820586 A1 CA2820586 A1 CA 2820586A1 CA 2820586 A CA2820586 A CA 2820586A CA 2820586 A CA2820586 A CA 2820586A CA 2820586 A1 CA2820586 A1 CA 2820586A1
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- laquinimod
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- multiple sclerosis
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- A—HUMAN NECESSITIES
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
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- A—HUMAN NECESSITIES
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- A61P25/00—Drugs for disorders of the nervous system
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Landscapes
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| EP2234485B1 (en) | 2007-12-20 | 2013-11-13 | Teva Pharmaceutical Industries, Ltd. | Stable laquinimod preparations |
| PL2458992T3 (pl) * | 2009-07-30 | 2016-07-29 | Teva Pharma | Leczenie choroby Leśniowskiego-Crohna z użyciem lakwinimodu |
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| DK2542079T3 (da) * | 2010-03-03 | 2014-08-25 | Teva Pharma | Behandling af reumatoid artritis med en kombination af laquinimod og methotrexat |
| SG183512A1 (en) * | 2010-03-03 | 2012-09-27 | Teva Pharma | Treatment of lupus nephritis using laquinimod |
| WO2012006538A1 (en) | 2010-07-09 | 2012-01-12 | Teva Pharmaceutical Industries Ltd. | Deuterated n-ethyl-n-phenyl-1,2-dihydro-4-hydroxy-5-chloro-1-methyl-2-oxoquinoline-3-carboxamide, salts and uses thereof |
| CA2851525A1 (en) | 2011-10-12 | 2013-04-18 | Teva Pharmaceutical Industries Ltd. | Treatment of multiple sclerosis with combination of laquinimod and fingolimod |
| CN104093310A (zh) | 2012-02-03 | 2014-10-08 | 泰华制药工业有限公司 | 拉喹莫德用于治疗一线抗TNFα疗法失败的克罗恩氏病患者的用途 |
| JP6215238B2 (ja) | 2012-02-16 | 2017-10-18 | テバ ファーマシューティカル インダストリーズ リミティド | Ｎ−エチル−ｎ−フェニル−１，２−ジヒドロ−４，５−ジ−ヒドロキシ−１−メチル−２−オキソ−３−キノリンカルボキサミド、その製剤、および使用 |
| TW201350467A (zh) | 2012-05-08 | 2013-12-16 | Teva Pharma | Ｎ－乙基－４－羥基－１－甲基－５－（甲基（２，３，４，５，６－五羥基己基）胺基）－２－側氧－ｎ－苯基－１，２－二氫喹啉－３－甲醯胺 |
| TW201400117A (zh) | 2012-06-05 | 2014-01-01 | Teva Pharma | 使用拉喹莫德治療眼發炎疾病 |
| TW201410244A (zh) | 2012-08-13 | 2014-03-16 | Teva Pharma | 用於治療ｇａｂａ媒介之疾病之拉喹莫德（ｌａｑｕｉｎｉｍｏｄ） |
| MX2015003608A (es) * | 2012-09-27 | 2015-06-05 | Teva Pharma | Combinacion de laquinimod y pridopidina para tratar trastornos neurodegenerativos. |
| BR112015007782A2 (pt) * | 2012-10-12 | 2017-07-04 | Teva Pharma | laquinimod para reduzir danos talâmicos na esclerose múltipla |
| EP2916915A4 (en) | 2012-11-07 | 2016-06-22 | Teva Pharma | LAQUINIMOD AMINE SALTS |
| BR112015019564A2 (pt) * | 2013-02-15 | 2017-07-18 | Teva Pharma | tratamento de esclerose múltipla com laquinimod |
| US20160046582A1 (en) | 2013-03-14 | 2016-02-18 | Teva Pharmaceutical Industries Ltd. | Crystals of laquinimod sodium and improved process for the manufacture thereof |
| US20160038435A1 (en) | 2013-03-14 | 2016-02-11 | Teva Pharmaceutical Industries Ltd. | Transdermal formulations of laquinimod |
| CA2933380A1 (en) * | 2013-12-20 | 2015-06-25 | Esther Lukasiewicz Hagai | Use of laquinimod to delay huntington's disease progression |
| HK1225969A1 (zh) * | 2014-01-17 | 2017-09-22 | Teva Pharmaceutical Industries Ltd | 利用低剂量的拉喹莫德治疗克隆氏病 |
| WO2015168103A1 (en) * | 2014-04-29 | 2015-11-05 | Teva Pharmaceutical Industries Ltd. | Laquinimod for the treatment of relapsing-remitting multiple sclerosis (rrms) patients with a high disability status |
| CN114699409A (zh) * | 2014-10-16 | 2022-07-05 | 诺华股份有限公司 | 包含辛波莫德和拉喹莫德的用于治疗多发性硬化症的组合 |
| MX2017008136A (es) | 2014-12-22 | 2018-03-06 | Teva Pharmaceuticals Int Gmbh | Sal de l-tartrato de pridopidina. |
| WO2020076809A1 (en) * | 2018-10-09 | 2020-04-16 | Medicinova, Inc. | Combination of ibudilast and interferon-beta and methods of using same |
| BR112022001138A2 (pt) * | 2019-07-22 | 2022-03-15 | Actelion Pharmaceuticals Ltd | Métodos de tratamento de esclerose múltipla |
| CN110688373A (zh) * | 2019-09-17 | 2020-01-14 | 杭州绿度信息技术有限公司 | 一种基于逻辑回归的offset方法 |
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| US20060205822A1 (en) * | 2004-12-22 | 2006-09-14 | Forest Laboratories, Inc. | 1-Aminocyclohexane derivatives for the treatment of multiple sclerosis, emotional lability and pseudobulbar affect |
| US9168286B2 (en) * | 2005-10-13 | 2015-10-27 | Human Genome Sciences, Inc. | Methods and compositions for use in treatment of patients with autoantibody positive disease |
| KR20150065951A (ko) * | 2006-06-12 | 2015-06-15 | 테바 파마슈티컬 인더스트리즈 리미티드 | 안정한 라퀴니모드 제제 |
| EP2680010A1 (en) * | 2007-02-08 | 2014-01-01 | Biogen Idec MA Inc. | Nrf2 screening assays and related methods and compositions |
| JP2012530701A (ja) * | 2009-06-19 | 2012-12-06 | テバ ファーマシューティカル インダストリーズ リミティド | 多発性硬化症のラキニモドでの治療 |
-
2011
- 2011-12-06 AU AU2011338647A patent/AU2011338647A1/en not_active Abandoned
- 2011-12-06 NZ NZ611628A patent/NZ611628A/en not_active IP Right Cessation
- 2011-12-06 EA EA201390827A patent/EA201390827A1/ru unknown
- 2011-12-06 EP EP11846599.6A patent/EP2648732A4/en not_active Withdrawn
- 2011-12-06 UA UAA201308448A patent/UA111959C2/uk unknown
- 2011-12-06 US US13/312,284 patent/US20120142730A1/en not_active Abandoned
- 2011-12-06 CA CA2820586A patent/CA2820586A1/en not_active Abandoned
- 2011-12-06 PH PH1/2013/501193A patent/PH12013501193A1/en unknown
- 2011-12-06 PE PE2013001357A patent/PE20140872A1/es not_active Application Discontinuation
- 2011-12-06 MX MX2013006464A patent/MX2013006464A/es unknown
- 2011-12-06 SG SG10201509831XA patent/SG10201509831XA/en unknown
- 2011-12-06 KR KR1020137017362A patent/KR20130124518A/ko not_active Ceased
- 2011-12-06 WO PCT/US2011/063460 patent/WO2012078591A1/en not_active Ceased
- 2011-12-06 SG SG2013042403A patent/SG190449A1/en unknown
- 2011-12-06 CN CN201180060414.8A patent/CN103260624B/zh not_active Expired - Fee Related
- 2011-12-06 BR BR112013014061A patent/BR112013014061A2/pt not_active Application Discontinuation
- 2011-12-06 JP JP2013543255A patent/JP2013544887A/ja active Pending
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2013
- 2013-06-05 CL CL2013001602A patent/CL2013001602A1/es unknown
- 2013-06-10 ZA ZA2013/04237A patent/ZA201304237B/en unknown
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2016
- 2016-12-26 JP JP2016251360A patent/JP2017095476A/ja active Pending
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2017
- 2017-02-22 IL IL250726A patent/IL250726A0/en unknown
- 2017-03-28 AU AU2017202055A patent/AU2017202055A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP2648732A4 (en) | 2014-04-30 |
| EA201390827A1 (ru) | 2013-12-30 |
| WO2012078591A1 (en) | 2012-06-14 |
| CN103260624A (zh) | 2013-08-21 |
| ZA201304237B (en) | 2014-08-27 |
| SG10201509831XA (en) | 2015-12-30 |
| CN103260624B (zh) | 2015-06-03 |
| NZ611628A (en) | 2015-06-26 |
| AU2011338647A8 (en) | 2013-09-05 |
| EP2648732A1 (en) | 2013-10-16 |
| KR20130124518A (ko) | 2013-11-14 |
| PH12013501193A1 (en) | 2013-07-15 |
| BR112013014061A2 (pt) | 2016-09-13 |
| WO2012078591A8 (en) | 2012-08-02 |
| UA111959C2 (uk) | 2016-07-11 |
| MX2013006464A (es) | 2013-07-29 |
| SG190449A1 (en) | 2013-07-31 |
| IL250726A0 (en) | 2017-04-30 |
| JP2013544887A (ja) | 2013-12-19 |
| CL2013001602A1 (es) | 2013-10-25 |
| AU2017202055A1 (en) | 2017-04-20 |
| JP2017095476A (ja) | 2017-06-01 |
| US20120142730A1 (en) | 2012-06-07 |
| AU2011338647A1 (en) | 2013-07-04 |
| PE20140872A1 (es) | 2014-08-09 |
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| FZDE | Discontinued |
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