PE20091022A1 - Anticuerpos anti-factor b y sus usos - Google Patents
Anticuerpos anti-factor b y sus usosInfo
- Publication number
- PE20091022A1 PE20091022A1 PE2008001904A PE2008001904A PE20091022A1 PE 20091022 A1 PE20091022 A1 PE 20091022A1 PE 2008001904 A PE2008001904 A PE 2008001904A PE 2008001904 A PE2008001904 A PE 2008001904A PE 20091022 A1 PE20091022 A1 PE 20091022A1
- Authority
- PE
- Peru
- Prior art keywords
- factor
- antibody
- humanized
- diabetic
- life chain
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Ophthalmology & Optometry (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
REFERIDO A UN ANTICUERPO O FRAGMENTO DE ANTICUERPO 1F7 ANTI-FACTOR B, MONOCLONAL QUIMERICO O HUMANIZADO, EL CUAL SE UNE A UN EPITOPE QUE INCLUYE RESIDUOS DE SITIOS ACTIVOS DEL FACTOR B, Y QUE COMPRENDE LAS SECUENCIAS DE REGION HIPERVARIABLE DE CADENA LIVIANA Y/O PESADA SEGUN SEC ID N°: 1 Y 2 RESPECTIVAMENTE. DICHO ANTICUERPO ES UTIL PARA EL TRATAMIENTO DE AFECCIONES OCULARES ASOCIADAS CON EL COMPLEMENTO, TALES COMO NEOVASCULARIZACION COROIDAL, DEGENERACION MACULAR RELACIONADA CON LA EDAD, RETINOPATIAS DIABETICAS, EDEMA MACULAR DIABETICO, MIOPIA PATOLOGICA
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US264807P | 2007-11-08 | 2007-11-08 |
Publications (1)
Publication Number | Publication Date |
---|---|
PE20091022A1 true PE20091022A1 (es) | 2009-07-16 |
Family
ID=40344464
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PE2008001904A PE20091022A1 (es) | 2007-11-08 | 2008-11-07 | Anticuerpos anti-factor b y sus usos |
Country Status (15)
Country | Link |
---|---|
US (4) | US8158762B2 (es) |
EP (1) | EP2209807A1 (es) |
JP (1) | JP2011503094A (es) |
KR (1) | KR20100105587A (es) |
CN (1) | CN101918444A (es) |
AR (1) | AR069233A1 (es) |
AU (1) | AU2008323939A1 (es) |
BR (1) | BRPI0820343A2 (es) |
CA (1) | CA2704973A1 (es) |
CL (1) | CL2008003313A1 (es) |
IL (1) | IL205577A0 (es) |
MX (1) | MX2010005115A (es) |
PE (1) | PE20091022A1 (es) |
TW (1) | TW200927170A (es) |
WO (1) | WO2009061910A1 (es) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
RS20120461A1 (en) | 2009-07-02 | 2013-06-28 | Musc Foundation For Research Development | METHODS FOR STIMULATION OF LIVER REGENERATION |
TWI407953B (zh) * | 2011-03-24 | 2013-09-11 | Univ Kaohsiung Medical | 用於調節補體因子b(cfb)表現的醫藥組合物 |
EP2855529A4 (en) * | 2012-05-24 | 2015-12-09 | Alexion Pharma Inc | HUMANIZED ANTI-FACTOR B ANTIBODIES |
KR102495018B1 (ko) | 2013-11-15 | 2023-02-06 | 아케비아 테라퓨틱스 인코포레이티드 | {[5-(3-클로로페닐)-3-하이드록시피리딘-2-카보닐]아미노}아세트산의 고체형, 이의 조성물 및 용도 |
KR20190003951A (ko) * | 2016-04-04 | 2019-01-10 | 바이오버라티브 유에스에이 인코포레이티드 | 항-보체 인자 bb 항체 및 이의 용도 |
US11524939B2 (en) | 2019-11-13 | 2022-12-13 | Akebia Therapeutics, Inc. | Solid forms of {[5-(3-chlorophenyl)-3-hydroxypyridine-2-carbonyl]amino} acetic acid |
Family Cites Families (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3773919A (en) | 1969-10-23 | 1973-11-20 | Du Pont | Polylactide-drug mixtures |
US4873191A (en) | 1981-06-12 | 1989-10-10 | Ohio University | Genetic transformation of zygotes |
NZ201705A (en) | 1981-08-31 | 1986-03-14 | Genentech Inc | Recombinant dna method for production of hepatitis b surface antigen in yeast |
DD266710A3 (de) | 1983-06-06 | 1989-04-12 | Ve Forschungszentrum Biotechnologie | Verfahren zur biotechnischen Herstellung van alkalischer Phosphatase |
US4736866A (en) | 1984-06-22 | 1988-04-12 | President And Fellows Of Harvard College | Transgenic non-human mammals |
US4879231A (en) | 1984-10-30 | 1989-11-07 | Phillips Petroleum Company | Transformation of yeasts of the genus pichia |
GB8516415D0 (en) | 1985-06-28 | 1985-07-31 | Celltech Ltd | Culture of animal cells |
GB8607679D0 (en) | 1986-03-27 | 1986-04-30 | Winter G P | Recombinant dna product |
GB8610600D0 (en) | 1986-04-30 | 1986-06-04 | Novo Industri As | Transformation of trichoderma |
JP3040121B2 (ja) | 1988-01-12 | 2000-05-08 | ジェネンテク,インコーポレイテッド | 増殖因子レセプターの機能を阻害することにより腫瘍細胞を処置する方法 |
ATE135397T1 (de) | 1988-09-23 | 1996-03-15 | Cetus Oncology Corp | Zellenzuchtmedium für erhöhtes zellenwachstum, zur erhöhung der langlebigkeit und expression der produkte |
FR2646437B1 (fr) | 1989-04-28 | 1991-08-30 | Transgene Sa | Nouvelles sequences d'adn, leur application en tant que sequence codant pour un peptide signal pour la secretion de proteines matures par des levures recombinantes, cassettes d'expression, levures transformees et procede de preparation de proteines correspondant |
EP0402226A1 (en) | 1989-06-06 | 1990-12-12 | Institut National De La Recherche Agronomique | Transformation vectors for yeast yarrowia |
DE3920358A1 (de) | 1989-06-22 | 1991-01-17 | Behringwerke Ag | Bispezifische und oligospezifische, mono- und oligovalente antikoerperkonstrukte, ihre herstellung und verwendung |
ATE297465T1 (de) | 1991-11-25 | 2005-06-15 | Enzon Inc | Verfahren zur herstellung von multivalenten antigenbindenden proteinen |
EP0752248B1 (en) | 1992-11-13 | 2000-09-27 | Idec Pharmaceuticals Corporation | Therapeutic application of chimeric and radiolabeled antibodies to human B lymphocyte restricted differentiation antigen for treatment of B cell lymphoma |
JP4753578B2 (ja) | 2002-06-03 | 2011-08-24 | ジェネンテック, インコーポレイテッド | 合成抗体ファージライブラリー |
WO2004103288A2 (en) * | 2003-05-13 | 2004-12-02 | New York Society For The Ruptured And Crippled Maintaining The Hospital For Special Surgery | Method of preventing recurrent miscarriages |
US7999082B2 (en) * | 2004-02-10 | 2011-08-16 | National Jewish Medical And Research Center | Anti-factor B antibodies |
KR20180002911A (ko) * | 2005-11-04 | 2018-01-08 | 제넨테크, 인크. | 안질환 치료를 위한 보체 경로 억제제의 용도 |
CA3148917A1 (en) | 2006-03-08 | 2007-09-13 | Archemix Llc | Complement binding aptamers and anti-c5 agents useful in the treatment of ocular disorders |
KR20090122465A (ko) * | 2007-03-01 | 2009-11-30 | 어드벤스드 비젼 테라피스, 인코포레이티드 | 염증성 질환의 치료 |
-
2008
- 2008-11-06 CN CN2008801243361A patent/CN101918444A/zh active Pending
- 2008-11-06 US US12/291,222 patent/US8158762B2/en not_active Expired - Fee Related
- 2008-11-06 CA CA2704973A patent/CA2704973A1/en not_active Abandoned
- 2008-11-06 MX MX2010005115A patent/MX2010005115A/es unknown
- 2008-11-06 AU AU2008323939A patent/AU2008323939A1/en not_active Abandoned
- 2008-11-06 JP JP2010533241A patent/JP2011503094A/ja active Pending
- 2008-11-06 WO PCT/US2008/082621 patent/WO2009061910A1/en active Application Filing
- 2008-11-06 EP EP08848036A patent/EP2209807A1/en not_active Withdrawn
- 2008-11-06 KR KR1020107012466A patent/KR20100105587A/ko not_active Application Discontinuation
- 2008-11-06 BR BRPI0820343A patent/BRPI0820343A2/pt not_active IP Right Cessation
- 2008-11-07 AR ARP080104888A patent/AR069233A1/es not_active Application Discontinuation
- 2008-11-07 TW TW097143224A patent/TW200927170A/zh unknown
- 2008-11-07 PE PE2008001904A patent/PE20091022A1/es not_active Application Discontinuation
- 2008-11-07 CL CL2008003313A patent/CL2008003313A1/es unknown
-
2010
- 2010-05-06 IL IL205577A patent/IL205577A0/en unknown
-
2012
- 2012-01-31 US US13/385,057 patent/US20120230997A1/en not_active Abandoned
-
2015
- 2015-10-06 US US14/876,655 patent/US20160024224A1/en not_active Abandoned
-
2017
- 2017-10-23 US US15/791,064 patent/US20180037667A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
AR069233A1 (es) | 2010-01-06 |
US20090123469A1 (en) | 2009-05-14 |
MX2010005115A (es) | 2010-05-27 |
CL2008003313A1 (es) | 2010-02-05 |
BRPI0820343A2 (pt) | 2017-08-22 |
US20120230997A1 (en) | 2012-09-13 |
US20180037667A1 (en) | 2018-02-08 |
CA2704973A1 (en) | 2009-05-14 |
US20160024224A1 (en) | 2016-01-28 |
CN101918444A (zh) | 2010-12-15 |
IL205577A0 (en) | 2010-11-30 |
KR20100105587A (ko) | 2010-09-29 |
TW200927170A (en) | 2009-07-01 |
WO2009061910A1 (en) | 2009-05-14 |
EP2209807A1 (en) | 2010-07-28 |
JP2011503094A (ja) | 2011-01-27 |
US8158762B2 (en) | 2012-04-17 |
AU2008323939A1 (en) | 2009-05-14 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG | Grant, registration | ||
FD | Application declared void or lapsed |